#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P14174	uniprotkb:Q92905	intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym)	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Burger-Kentischer et al. (2005)	pubmed:15757663|imex:IM-10830|mint:MINT-5217586	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7522890|mint:MINT-58209|imex:IM-10830-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N|mint:MINT-1339841(identity)	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|mint:MINT-1339832(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/04/05	2014/10/16	rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	intact-crc:21E8F717EB65842B|rigid:CPuNB3FD5i6aFbsKMGRbvA/53CM	false	tag:?-?(MINT-1339842)	tag:?-?(MINT-1339836)|binding-associated region:53-142(MINT-1339833)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92905	uniprotkb:P14174	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym)	psi-mi:"MI:0069"(mass spectrometry studies of complexes)	Burger-Kentischer et al. (2005)	pubmed:15757663|imex:IM-10830|mint:MINT-5217586	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7522940|mint:MINT-58211|imex:IM-10830-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|mint:MINT-1339853(identity)	refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N|mint:MINT-1339861(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/04/05	2014/10/16	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606	intact-crc:CDBC16E7DE19B1DE|rigid:CPuNB3FD5i6aFbsKMGRbvA/53CM	false	binding-associated region:53-142(MINT-1339854)	binding-associated region:50-65(MINT-1339862)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92905	uniprotkb:P14174	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Burger-Kentischer et al. (2005)	pubmed:15757663|imex:IM-10830|mint:MINT-5217586	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7522988|mint:MINT-58210|imex:IM-10830-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|mint:MINT-1339874(identity)	refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N|mint:MINT-1339881(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/04/05	2014/10/16	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606	intact-crc:1E0D8D2921F6827D|rigid:CPuNB3FD5i6aFbsKMGRbvA/53CM	false	binding-associated region:53-142(MINT-1339875)	tag:?-?(MINT-1339882)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7L5N1	uniprotkb:P14174	intact:EBI-486838|uniprotkb:O15387|uniprotkb:A4D2A3|ensembl:ENSP00000304102	intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779	psi-mi:csn6_human(display_long)|uniprotkb:COPS6(gene name)|psi-mi:COPS6(display_short)|uniprotkb:CSN6(gene name synonym)|uniprotkb:HVIP(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 6(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)|uniprotkb:MOV34 homolog(gene name synonym)	psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Burger-Kentischer et al. (2005)	pubmed:15757663|imex:IM-10830|mint:MINT-5217586	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7523063|mint:MINT-58212|imex:IM-10830-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006824.2|ensembl:ENSG00000168090(gene)|ensembl:ENST00000303904(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR033859|interpro:IPR024969|interpro:IPR037518|mint:Q7L5N1|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4QFT|rcsb pdb:4R14|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|dip:DIP-32655N|mint:MINT-1339893(identity)	refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N|mint:MINT-1339897(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/04/05	2014/10/16	rogid:hyuYyAujJCJtbfS2tJ+UgH7jWP89606	rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606	intact-crc:9A3D1CCC03AB5273|rigid:PXvbFpuwXcYfpWZEPrj3cG9ST0s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)