#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9WVK0 uniprotkb:P29754 intact:EBI-645964|uniprotkb:Q9D8Z8|uniprotkb:Q9D940|uniprotkb:B2KFL8|uniprotkb:Q3U7X6|ensembl:ENSMUSP00000030865 intact:EBI-765178|ensembl:ENSMUSP00000070958 psi-mi:atrap_mouse(display_long)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:Agtrap(gene name)|psi-mi:Agtrap(display_short)|uniprotkb:Atrap(gene name synonym) psi-mi:agtra_mouse(display_long)|uniprotkb:Angiotensin II type-1A receptor(gene name synonym)|uniprotkb:Agtr1a(gene name)|psi-mi:Agtr1a(display_short)|uniprotkb:Agtr1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tanaka et al. (2005) pubmed:15757644|imex:IM-11360|mint:MINT-5217577 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7514663|mint:MINT-58239|imex:IM-11360-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033772.2|ensembl:ENSMUSG00000029007(gene)|ensembl:ENSMUST00000030865(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009436(Angiotensin II, type I receptor-associated)|mint:MINT-1339617(identity) refseq:NP_796296.1|refseq:XP_011242566.1|refseq:XP_006516597.1|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031968"(organelle outer membrane)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042756"(drinking behavior)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1905665"(positive regulation of calcium ion import across plasma membrane)|interpro:IPR000190(AT1 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-MMU-375276|reactome:R-MMU-416476|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0030425"(dendrite)|ensembl:ENSMUSG00000049115(gene)|ensembl:ENSMUST00000066412(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001596"(angiotensin type I receptor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002001"(renin secretion into blood stream)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006885"(regulation of pH)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0012505"(endomembrane system)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0002035"(brain renin-angiotensin system)|mint:MINT-1339611(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2005/04/06 2014/10/16 rogid:lsUO0uebiZ/LA9e3ug/HJOlpYSI10090 rogid:ryDNlkCRdPZjShpDK2rs1BHaOks10090 intact-crc:81B032E69188191F|rigid:DcfDusONsOQHYyJYFba3tL9UlNA false tag:?-?(MINT-1339618) tag:?-?(MINT-1339612) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29754 uniprotkb:Q9WVK0 intact:EBI-765178|ensembl:ENSMUSP00000070958 intact:EBI-645964|uniprotkb:Q9D8Z8|uniprotkb:Q9D940|uniprotkb:B2KFL8|uniprotkb:Q3U7X6|ensembl:ENSMUSP00000030865 psi-mi:agtra_mouse(display_long)|uniprotkb:Angiotensin II type-1A receptor(gene name synonym)|uniprotkb:Agtr1a(gene name)|psi-mi:Agtr1a(display_short)|uniprotkb:Agtr1(gene name synonym) psi-mi:atrap_mouse(display_long)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:Agtrap(gene name)|psi-mi:Agtrap(display_short)|uniprotkb:Atrap(gene name synonym) psi-mi:"MI:0428"(imaging technique) Tanaka et al. (2005) pubmed:15757644|imex:IM-11360|mint:MINT-5217577 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7514714|mint:MINT-58240|imex:IM-11360-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796296.1|refseq:XP_011242566.1|refseq:XP_006516597.1|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031968"(organelle outer membrane)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042756"(drinking behavior)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1905665"(positive regulation of calcium ion import across plasma membrane)|interpro:IPR000190(AT1 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-MMU-375276|reactome:R-MMU-416476|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0030425"(dendrite)|ensembl:ENSMUSG00000049115(gene)|ensembl:ENSMUST00000066412(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001596"(angiotensin type I receptor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002001"(renin secretion into blood stream)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006885"(regulation of pH)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0012505"(endomembrane system)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0002035"(brain renin-angiotensin system)|mint:MINT-1339629(identity) refseq:NP_033772.2|ensembl:ENSMUSG00000029007(gene)|ensembl:ENSMUST00000030865(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009436(Angiotensin II, type I receptor-associated)|mint:MINT-1339636(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:Stimulation with AngII induces co-localization in intracellular compartments|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2005/04/06 2014/10/16 rogid:ryDNlkCRdPZjShpDK2rs1BHaOks10090 rogid:lsUO0uebiZ/LA9e3ug/HJOlpYSI10090 intact-crc:4664482A24F258CF|rigid:DcfDusONsOQHYyJYFba3tL9UlNA false tag:?-?(MINT-1339630) tag:?-?(MINT-1339637) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification)