#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B
uniprotkb:Q01112 uniprotkb:P40996 intact:EBI-767502|ensemblfungi:"SPAC110.03.1:pep" intact:EBI-767302|ensemblfungi:"SPAC22H10.07.1:pep" psi-mi:cdc42_schpo(display_long)|uniprotkb:CDC42Sp(gene name synonym)|uniprotkb:cdc42(gene name)|psi-mi:cdc42(display_short)|uniprotkb:SPAC110.03(orf name) psi-mi:scd2_schpo(display_long)|uniprotkb:ral3(gene name synonym)|uniprotkb:SPAC22H10.07(orf name)|uniprotkb:scd2(gene name)|psi-mi:scd2(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Wheatley et al. (2005) pubmed:15631622|mint:MINT-5217443 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7442158|mint:MINT-68614 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593536.1|dip:DIP-275N|mint:Q01112|ensemblfungi:SPAC110.03(gene)|ensemblfungi:SPAC110.03.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032951"(regulation of beta-glucan biosynthetic process)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5626467|reactome:R-SPO-5627123|reactome:R-SPO-5687128|reactome:R-SPO-9013148|reactome:R-SPO-9013406|reactome:R-SPO-9013409|go:"GO:0006897"(endocytosis)|mint:MINT-1215008(identity) refseq:NP_593744.1|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR030507|interpro:IPR036028|interpro:IPR036871|reactome:R-SPO-5668599|ensemblfungi:SPAC22H10.07(gene)|ensemblfungi:SPAC22H10.07.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051286"(cell tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR018247|reactome:R-SPO-1236973|reactome:R-SPO-3299685|reactome:R-SPO-9013148|mint:MINT-1215000(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2 T1|comment:"Interaction with active form of Cdc42 (Q61L)"|kd:28 nanomolar|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/25 2014/10/16 rogid:Hm+T2A2V+AZYh2VtuqATJiUDgUI284812 rogid:8pVLuwhCoDW2nQTMcFKfAOqJ72s284812 intact-crc:A8396BE8A90A8367|rigid:QN9JkJ8j0LESFXfTO6bXGpqQvaM false mutation:61-61(MINT-1215009) binding-associated region:1-266(MINT-1215001) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01112 uniprotkb:P40996 intact:EBI-767502|ensemblfungi:"SPAC110.03.1:pep" intact:EBI-767302|ensemblfungi:"SPAC22H10.07.1:pep" psi-mi:cdc42_schpo(display_long)|uniprotkb:CDC42Sp(gene name synonym)|uniprotkb:cdc42(gene name)|psi-mi:cdc42(display_short)|uniprotkb:SPAC110.03(orf name) psi-mi:scd2_schpo(display_long)|uniprotkb:ral3(gene name synonym)|uniprotkb:SPAC22H10.07(orf name)|uniprotkb:scd2(gene name)|psi-mi:scd2(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Wheatley et al. (2005) pubmed:15631622|mint:MINT-5217443 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7442221|mint:MINT-68617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593536.1|dip:DIP-275N|mint:Q01112|ensemblfungi:SPAC110.03(gene)|ensemblfungi:SPAC110.03.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032951"(regulation of beta-glucan biosynthetic process)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5626467|reactome:R-SPO-5627123|reactome:R-SPO-5687128|reactome:R-SPO-9013148|reactome:R-SPO-9013406|reactome:R-SPO-9013409|go:"GO:0006897"(endocytosis)|mint:MINT-1214968(identity) refseq:NP_593744.1|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR030507|interpro:IPR036028|interpro:IPR036871|reactome:R-SPO-5668599|ensemblfungi:SPAC22H10.07(gene)|ensemblfungi:SPAC22H10.07.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051286"(cell tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR018247|reactome:R-SPO-1236973|reactome:R-SPO-3299685|reactome:R-SPO-9013148|mint:MINT-1214960(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T3|comment:"Interaction with active form of Cdc42 (Q61L)
"|kd:1.71 micromolar|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/25 2014/10/16 rogid:Hm+T2A2V+AZYh2VtuqATJiUDgUI284812 rogid:8pVLuwhCoDW2nQTMcFKfAOqJ72s284812 intact-crc:2FD171F41F7A59CC|rigid:QN9JkJ8j0LESFXfTO6bXGpqQvaM false mutation:61-61(MINT-1214969) binding-associated region:110-220(MINT-1214961) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01112 uniprotkb:P40996 intact:EBI-767502|ensemblfungi:"SPAC110.03.1:pep" intact:EBI-767302|ensemblfungi:"SPAC22H10.07.1:pep" psi-mi:cdc42_schpo(display_long)|uniprotkb:CDC42Sp(gene name synonym)|uniprotkb:cdc42(gene name)|psi-mi:cdc42(display_short)|uniprotkb:SPAC110.03(orf name) psi-mi:scd2_schpo(display_long)|uniprotkb:ral3(gene name synonym)|uniprotkb:SPAC22H10.07(orf name)|uniprotkb:scd2(gene name)|psi-mi:scd2(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Wheatley et al. (2005) pubmed:15631622|mint:MINT-5217443 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7442183|mint:MINT-68615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593536.1|dip:DIP-275N|mint:Q01112|ensemblfungi:SPAC110.03(gene)|ensemblfungi:SPAC110.03.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032951"(regulation of beta-glucan biosynthetic process)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5626467|reactome:R-SPO-5627123|reactome:R-SPO-5687128|reactome:R-SPO-9013148|reactome:R-SPO-9013406|reactome:R-SPO-9013409|go:"GO:0006897"(endocytosis)|mint:MINT-1215030(identity) refseq:NP_593744.1|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR030507|interpro:IPR036028|interpro:IPR036871|reactome:R-SPO-5668599|ensemblfungi:SPAC22H10.07(gene)|ensemblfungi:SPAC22H10.07.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051286"(cell tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR018247|reactome:R-SPO-1236973|reactome:R-SPO-3299685|reactome:R-SPO-9013148|mint:MINT-1215020(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Interaction with active form of Cdc42 (Q61L)
"|kd:3 micromolar|figure legend:T2 T3|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/25 2014/10/16 rogid:Hm+T2A2V+AZYh2VtuqATJiUDgUI284812 rogid:8pVLuwhCoDW2nQTMcFKfAOqJ72s284812 intact-crc:DB0764F24524C098|rigid:QN9JkJ8j0LESFXfTO6bXGpqQvaM false mutation:61-61(MINT-1215031) mutation decreasing interaction:62-62(MINT-1215024)|binding-associated region:1-86(MINT-1215021) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01112 uniprotkb:P40996 intact:EBI-767502|ensemblfungi:"SPAC110.03.1:pep" intact:EBI-767302|ensemblfungi:"SPAC22H10.07.1:pep" psi-mi:cdc42_schpo(display_long)|uniprotkb:CDC42Sp(gene name synonym)|uniprotkb:cdc42(gene name)|psi-mi:cdc42(display_short)|uniprotkb:SPAC110.03(orf name) psi-mi:scd2_schpo(display_long)|uniprotkb:ral3(gene name synonym)|uniprotkb:SPAC22H10.07(orf name)|uniprotkb:scd2(gene name)|psi-mi:scd2(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Wheatley et al. (2005) pubmed:15631622|mint:MINT-5217443 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7442250|mint:MINT-68618 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593536.1|dip:DIP-275N|mint:Q01112|ensemblfungi:SPAC110.03(gene)|ensemblfungi:SPAC110.03.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032951"(regulation of beta-glucan biosynthetic process)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5626467|reactome:R-SPO-5627123|reactome:R-SPO-5687128|reactome:R-SPO-9013148|reactome:R-SPO-9013406|reactome:R-SPO-9013409|go:"GO:0006897"(endocytosis)|mint:MINT-1214989(identity) refseq:NP_593744.1|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR030507|interpro:IPR036028|interpro:IPR036871|reactome:R-SPO-5668599|ensemblfungi:SPAC22H10.07(gene)|ensemblfungi:SPAC22H10.07.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051286"(cell tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR018247|reactome:R-SPO-1236973|reactome:R-SPO-3299685|reactome:R-SPO-9013148|mint:MINT-1214982(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:"Interaction with active form of Cdc42 (Q61L)
"|kd:7 micromolar|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/25 2014/10/16 rogid:Hm+T2A2V+AZYh2VtuqATJiUDgUI284812 rogid:8pVLuwhCoDW2nQTMcFKfAOqJ72s284812 intact-crc:158B576C0526A988|rigid:QN9JkJ8j0LESFXfTO6bXGpqQvaM false mutation:61-61(MINT-1214990) binding-associated region:110-220(MINT-1214983) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40996 uniprotkb:Q01112 intact:EBI-767302|ensemblfungi:"SPAC22H10.07.1:pep" intact:EBI-767502|ensemblfungi:"SPAC110.03.1:pep" psi-mi:scd2_schpo(display_long)|uniprotkb:ral3(gene name synonym)|uniprotkb:SPAC22H10.07(orf name)|uniprotkb:scd2(gene name)|psi-mi:scd2(display_short) psi-mi:cdc42_schpo(display_long)|uniprotkb:CDC42Sp(gene name synonym)|uniprotkb:cdc42(gene name)|psi-mi:cdc42(display_short)|uniprotkb:SPAC110.03(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Wheatley et al. (2005) pubmed:15631622|mint:MINT-5217443 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7442280|mint:MINT-68616 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593744.1|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR030507|interpro:IPR036028|interpro:IPR036871|reactome:R-SPO-5668599|ensemblfungi:SPAC22H10.07(gene)|ensemblfungi:SPAC22H10.07.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051286"(cell tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR018247|reactome:R-SPO-1236973|reactome:R-SPO-3299685|reactome:R-SPO-9013148|mint:MINT-1215044(identity) refseq:NP_593536.1|dip:DIP-275N|mint:Q01112|ensemblfungi:SPAC110.03(gene)|ensemblfungi:SPAC110.03.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032951"(regulation of beta-glucan biosynthetic process)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5626467|reactome:R-SPO-5627123|reactome:R-SPO-5687128|reactome:R-SPO-9013148|reactome:R-SPO-9013406|reactome:R-SPO-9013409|go:"GO:0006897"(endocytosis)|mint:MINT-1215049(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:"Interaction with active form of Cdc42 (Q61L)
"|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/25 2014/10/16 rogid:8pVLuwhCoDW2nQTMcFKfAOqJ72s284812 rogid:Hm+T2A2V+AZYh2VtuqATJiUDgUI284812 intact-crc:48852060A7C07027|rigid:QN9JkJ8j0LESFXfTO6bXGpqQvaM false - mutation:61-61(MINT-1215050) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)