#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13057 uniprotkb:P23443 intact:EBI-745967|uniprotkb:Q6GS23|uniprotkb:Q8NBM7|uniprotkb:Q8NEW1|uniprotkb:Q8WXD4|uniprotkb:Q9NRM3|uniprotkb:B2RA78|uniprotkb:B4DLU0|ensembl:ENSP00000377406|ensembl:ENSP00000393564 intact:EBI-1775921|uniprotkb:B2R779|uniprotkb:B4DTG1|uniprotkb:F6UYM1|intact:EBI-11107861|uniprotkb:B4DLT4|uniprotkb:E7ESB8|uniprotkb:Q7Z721|ensembl:ENSP00000225577 psi-mi:coasy_human(display_long)|uniprotkb:NBP(gene name synonym)|uniprotkb:POV-2(gene name synonym)|uniprotkb:COASY(gene name)|psi-mi:COASY(display_short)|uniprotkb:PSEC0106(orf name) psi-mi:ks6b1_human(display_long)|uniprotkb:RPS6KB1(gene name)|psi-mi:RPS6KB1(display_short)|uniprotkb:STK14A(gene name synonym)|uniprotkb:Ribosomal protein S6 kinase I(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase alpha(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14A(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Nemazanyy et al. (2004) pubmed:15589845|mint:MINT-5217396 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7416479|mint:MINT-51062 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035994.1|refseq:NP_001035997.2|refseq:NP_079509.5|refseq:XP_011523602.1|ensembl:ENSG00000068120(gene)|ensembl:ENST00000393818(transcript)|ensembl:ENST00000421097(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR027417|reactome:R-HSA-196783|refseq:XP_006722179.1|refseq:XP_016880657.1|mint:MINT-1212857(identity) refseq:NP_003152.1|refseq:NP_001258989.1|refseq:NP_001258971.1|refseq:NP_001258972.1|refseq:NP_001258973.1|dip:DIP-29986N|ensembl:ENSG00000108443(gene)|ensembl:ENST00000225577(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:P23443|rcsb pdb:3A60|rcsb pdb:3A61|rcsb pdb:3A62|rcsb pdb:3WE4|rcsb pdb:3WF5|rcsb pdb:3WF6|rcsb pdb:3WF7|rcsb pdb:3WF8|rcsb pdb:3WF9|rcsb pdb:4L3J|rcsb pdb:4L3L|rcsb pdb:4L42|rcsb pdb:4L43|rcsb pdb:4L44|rcsb pdb:4L45|rcsb pdb:4L46|rcsb pdb:4RLO|rcsb pdb:4RLP|rcsb pdb:5WBH|rcsb pdb:5WBK|reactome:R-HSA-166208|mint:MINT-1212851(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:homomint|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/08 2014/10/16 rogid:yMK1IODpj01+JZsNsayJCgEHpyo9606 rogid:rEFXLi6QTM8wdG7FNx1er6EzPFM9606 intact-crc:56A19F8F826A47B5|rigid:M+lYhpa7w0z28eH51dmaB6wDL40 false tag:?-?(MINT-1212858) tag:?-?(MINT-1212852) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23443 uniprotkb:Q13057 intact:EBI-1775921|uniprotkb:B2R779|uniprotkb:B4DTG1|uniprotkb:F6UYM1|intact:EBI-11107861|uniprotkb:B4DLT4|uniprotkb:E7ESB8|uniprotkb:Q7Z721|ensembl:ENSP00000225577 intact:EBI-745967|uniprotkb:Q6GS23|uniprotkb:Q8NBM7|uniprotkb:Q8NEW1|uniprotkb:Q8WXD4|uniprotkb:Q9NRM3|uniprotkb:B2RA78|uniprotkb:B4DLU0|ensembl:ENSP00000377406|ensembl:ENSP00000393564 psi-mi:ks6b1_human(display_long)|uniprotkb:RPS6KB1(gene name)|psi-mi:RPS6KB1(display_short)|uniprotkb:STK14A(gene name synonym)|uniprotkb:Ribosomal protein S6 kinase I(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase alpha(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14A(gene name synonym) psi-mi:coasy_human(display_long)|uniprotkb:NBP(gene name synonym)|uniprotkb:POV-2(gene name synonym)|uniprotkb:COASY(gene name)|psi-mi:COASY(display_short)|uniprotkb:PSEC0106(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Nemazanyy et al. (2004) pubmed:15589845|mint:MINT-5217396 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7416532|mint:MINT-51063 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003152.1|refseq:NP_001258989.1|refseq:NP_001258971.1|refseq:NP_001258972.1|refseq:NP_001258973.1|dip:DIP-29986N|ensembl:ENSG00000108443(gene)|ensembl:ENST00000225577(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:P23443|rcsb pdb:3A60|rcsb pdb:3A61|rcsb pdb:3A62|rcsb pdb:3WE4|rcsb pdb:3WF5|rcsb pdb:3WF6|rcsb pdb:3WF7|rcsb pdb:3WF8|rcsb pdb:3WF9|rcsb pdb:4L3J|rcsb pdb:4L3L|rcsb pdb:4L42|rcsb pdb:4L43|rcsb pdb:4L44|rcsb pdb:4L45|rcsb pdb:4L46|rcsb pdb:4RLO|rcsb pdb:4RLP|rcsb pdb:5WBH|rcsb pdb:5WBK|reactome:R-HSA-166208|mint:MINT-1212752(identity) refseq:NP_001035994.1|refseq:NP_001035997.2|refseq:NP_079509.5|refseq:XP_011523602.1|ensembl:ENSG00000068120(gene)|ensembl:ENST00000393818(transcript)|ensembl:ENST00000421097(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR027417|reactome:R-HSA-196783|refseq:XP_006722179.1|refseq:XP_016880657.1|mint:MINT-1212758(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:homomint|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/08 2014/10/16 rogid:rEFXLi6QTM8wdG7FNx1er6EzPFM9606 rogid:yMK1IODpj01+JZsNsayJCgEHpyo9606 intact-crc:B783AD7D6EEDB026|rigid:M+lYhpa7w0z28eH51dmaB6wDL40 false tag:?-?(MINT-1212753) tag:?-?(MINT-1212763)|binding-associated region:187-563(MINT-1212759) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBS0 uniprotkb:Q13057 intact:EBI-3905921|uniprotkb:B2RMZ9|uniprotkb:O94809|uniprotkb:Q9UEC1|ensembl:ENSP00000308413|uniprotkb:B4DML8 intact:EBI-745967|uniprotkb:Q6GS23|uniprotkb:Q8NBM7|uniprotkb:Q8NEW1|uniprotkb:Q8WXD4|uniprotkb:Q9NRM3|uniprotkb:B2RA78|uniprotkb:B4DLU0|ensembl:ENSP00000377406|ensembl:ENSP00000393564 psi-mi:ks6b2_human(display_long)|uniprotkb:RPS6KB2(gene name)|psi-mi:RPS6KB2(display_short)|uniprotkb:STK14B(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 2(gene name synonym)|uniprotkb:S6 kinase-related kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14B(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase beta(gene name synonym) psi-mi:coasy_human(display_long)|uniprotkb:NBP(gene name synonym)|uniprotkb:POV-2(gene name synonym)|uniprotkb:COASY(gene name)|psi-mi:COASY(display_short)|uniprotkb:PSEC0106(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Nemazanyy et al. (2004) pubmed:15589845|mint:MINT-5217396 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7416556|mint:MINT-51121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003943.2|ensembl:ENSG00000175634(gene)|ensembl:ENST00000312629(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031929"(TOR signaling)|go:"GO:0042277"(peptide binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q9UBS0|reactome:R-HSA-198693|reactome:R-HSA-5674400|mint:MINT-1212835(identity) refseq:NP_001035994.1|refseq:NP_001035997.2|refseq:NP_079509.5|refseq:XP_011523602.1|ensembl:ENSG00000068120(gene)|ensembl:ENST00000393818(transcript)|ensembl:ENST00000421097(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR027417|reactome:R-HSA-196783|refseq:XP_006722179.1|refseq:XP_016880657.1|mint:MINT-1212841(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:homomint|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/08 2014/10/16 rogid:5+kV2nr99KWLmrnfXt7Vr6L83xM9606 rogid:yMK1IODpj01+JZsNsayJCgEHpyo9606 intact-crc:58972307D65F7909|rigid:X3pwwf7fbjfS39Vtfm7SC2fjm5g false tag:?-?(MINT-1212836) tag:?-?(MINT-1212842) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23443 uniprotkb:Q13057 intact:EBI-1775921|uniprotkb:B2R779|uniprotkb:B4DTG1|uniprotkb:F6UYM1|intact:EBI-11107861|uniprotkb:B4DLT4|uniprotkb:E7ESB8|uniprotkb:Q7Z721|ensembl:ENSP00000225577 intact:EBI-745967|uniprotkb:Q6GS23|uniprotkb:Q8NBM7|uniprotkb:Q8NEW1|uniprotkb:Q8WXD4|uniprotkb:Q9NRM3|uniprotkb:B2RA78|uniprotkb:B4DLU0|ensembl:ENSP00000377406|ensembl:ENSP00000393564 psi-mi:ks6b1_human(display_long)|uniprotkb:RPS6KB1(gene name)|psi-mi:RPS6KB1(display_short)|uniprotkb:STK14A(gene name synonym)|uniprotkb:Ribosomal protein S6 kinase I(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase alpha(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14A(gene name synonym) psi-mi:coasy_human(display_long)|uniprotkb:NBP(gene name synonym)|uniprotkb:POV-2(gene name synonym)|uniprotkb:COASY(gene name)|psi-mi:COASY(display_short)|uniprotkb:PSEC0106(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Nemazanyy et al. (2004) pubmed:15589845|mint:MINT-5217396 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7416574|mint:MINT-51122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003152.1|refseq:NP_001258989.1|refseq:NP_001258971.1|refseq:NP_001258972.1|refseq:NP_001258973.1|dip:DIP-29986N|ensembl:ENSG00000108443(gene)|ensembl:ENST00000225577(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:P23443|rcsb pdb:3A60|rcsb pdb:3A61|rcsb pdb:3A62|rcsb pdb:3WE4|rcsb pdb:3WF5|rcsb pdb:3WF6|rcsb pdb:3WF7|rcsb pdb:3WF8|rcsb pdb:3WF9|rcsb pdb:4L3J|rcsb pdb:4L3L|rcsb pdb:4L42|rcsb pdb:4L43|rcsb pdb:4L44|rcsb pdb:4L45|rcsb pdb:4L46|rcsb pdb:4RLO|rcsb pdb:4RLP|rcsb pdb:5WBH|rcsb pdb:5WBK|reactome:R-HSA-166208|mint:MINT-1212811(identity) refseq:NP_001035994.1|refseq:NP_001035997.2|refseq:NP_079509.5|refseq:XP_011523602.1|ensembl:ENSG00000068120(gene)|ensembl:ENST00000393818(transcript)|ensembl:ENST00000421097(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR027417|reactome:R-HSA-196783|refseq:XP_006722179.1|refseq:XP_016880657.1|mint:MINT-1212821(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2D|comment:homomint|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/08 2014/10/16 rogid:rEFXLi6QTM8wdG7FNx1er6EzPFM9606 rogid:yMK1IODpj01+JZsNsayJCgEHpyo9606 intact-crc:95BF368BAB1C9943|rigid:M+lYhpa7w0z28eH51dmaB6wDL40 false tag:?-?(MINT-1212816)|binding-associated region:75-525(IPR000719) tag:?-?(MINT-1212826)|binding-associated region:187-563(MINT-1212822) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5XIA5 uniprotkb:P67999 intact:EBI-7416612|intact:MINT-1212787|ensembl:ENSRNOP00000027061 intact:EBI-2639458|uniprotkb:P21425|ensembl:ENSRNOP00000005226 psi-mi:q5xia5_rat(display_long)|uniprotkb:Coasy(gene name)|psi-mi:Coasy(display_short) psi-mi:ks6b1_rat(display_long)|uniprotkb:Rps6kb1(gene name)|psi-mi:Rps6kb1(display_short)|uniprotkb:Ribosomal protein S6 kinase I(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase alpha(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nemazanyy et al. (2004) pubmed:15589845|mint:MINT-5217396 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7416632|mint:MINT-51125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001006955.1|rgd:1549767|refseq:XP_006247338.1|ensembl:ENSRNOG00000019918(gene)|ensembl:ENSRNOT00000027061(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015937"(coenzyme A biosynthetic process)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-RNO-196783|interpro:IPR027417|mint:MINT-1212803(identity) rgd:620683|refseq:NP_114191.1|ensembl:ENSRNOG00000003919(gene)|ensembl:ENSRNOT00000005226(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007281"(germ cell development)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0009611"(response to wounding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009749"(response to glucose)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0033762"(response to glucagon)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043201"(response to leucine)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0106311"|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:P67999|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|reactome:R-RNO-166208|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0106310"(protein serine kinase activity)|mint:MINT-1212799(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/01/08 2014/10/16 rogid:dQRph35YRQSie7LGQdQ/poMduVU10116 rogid:hBuNefgCfqyO/LhEhClgcQrTjlM10116 intact-crc:5CC320CFB020E3E3|rigid:cp8rfz9vyM+k20Les+Li4cPrWg0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P23443 uniprotkb:Q13057 intact:EBI-1775921|uniprotkb:B2R779|uniprotkb:B4DTG1|uniprotkb:F6UYM1|intact:EBI-11107861|uniprotkb:B4DLT4|uniprotkb:E7ESB8|uniprotkb:Q7Z721|ensembl:ENSP00000225577 intact:EBI-745967|uniprotkb:Q6GS23|uniprotkb:Q8NBM7|uniprotkb:Q8NEW1|uniprotkb:Q8WXD4|uniprotkb:Q9NRM3|uniprotkb:B2RA78|uniprotkb:B4DLU0|ensembl:ENSP00000377406|ensembl:ENSP00000393564 psi-mi:ks6b1_human(display_long)|uniprotkb:RPS6KB1(gene name)|psi-mi:RPS6KB1(display_short)|uniprotkb:STK14A(gene name synonym)|uniprotkb:Ribosomal protein S6 kinase I(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase alpha(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14A(gene name synonym) psi-mi:coasy_human(display_long)|uniprotkb:NBP(gene name synonym)|uniprotkb:POV-2(gene name synonym)|uniprotkb:COASY(gene name)|psi-mi:COASY(display_short)|uniprotkb:PSEC0106(orf name) psi-mi:"MI:0107"(surface plasmon resonance) Nemazanyy et al. (2004) pubmed:15589845|mint:MINT-5217396 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7416672|mint:MINT-51123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003152.1|refseq:NP_001258989.1|refseq:NP_001258971.1|refseq:NP_001258972.1|refseq:NP_001258973.1|dip:DIP-29986N|ensembl:ENSG00000108443(gene)|ensembl:ENST00000225577(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:P23443|rcsb pdb:3A60|rcsb pdb:3A61|rcsb pdb:3A62|rcsb pdb:3WE4|rcsb pdb:3WF5|rcsb pdb:3WF6|rcsb pdb:3WF7|rcsb pdb:3WF8|rcsb pdb:3WF9|rcsb pdb:4L3J|rcsb pdb:4L3L|rcsb pdb:4L42|rcsb pdb:4L43|rcsb pdb:4L44|rcsb pdb:4L45|rcsb pdb:4L46|rcsb pdb:4RLO|rcsb pdb:4RLP|rcsb pdb:5WBH|rcsb pdb:5WBK|reactome:R-HSA-166208|mint:MINT-1212869(identity) refseq:NP_001035994.1|refseq:NP_001035997.2|refseq:NP_079509.5|refseq:XP_011523602.1|ensembl:ENSG00000068120(gene)|ensembl:ENST00000393818(transcript)|ensembl:ENST00000421097(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR027417|reactome:R-HSA-196783|refseq:XP_006722179.1|refseq:XP_016880657.1|mint:MINT-1212876(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|kd:184 nanomolar|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/01/08 2014/10/16 rogid:rEFXLi6QTM8wdG7FNx1er6EzPFM9606 rogid:yMK1IODpj01+JZsNsayJCgEHpyo9606 intact-crc:6AACBD39F6E1392B|rigid:M+lYhpa7w0z28eH51dmaB6wDL40 false tag:?-?(MINT-1212870) tag:?-?(MINT-1212877) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)