#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P81274 uniprotkb:P63096 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 - - - - taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 intact-crc:7326620D8BDFB2C7|rigid:pxd+qI7DOVU3Fu2J4bHxysDCeYQ false ha tag:n-n myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P63096 uniprotkb:Q14980 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618676 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - comment:Interaction between gnai1 and numa1 requires gpsm2. taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2005/07/13 2014/10/16 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:273FE9B347F9D51E|rigid:o36TQH4EJOzg811PZo1TNmsF3So false myc tag:c-c binding-associated region:1818-2001|ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P81274 uniprotkb:Q14980 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0096"(pull down) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618688 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - stimulant:interaction is stimulated by gnai1. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:830253E0457F3A81|rigid:TEm26hi2OIDot9VFNuwSn01IiMk false binding-associated region:8-380(IPR001440)|glutathione s tranferase tag:n-n tag:n-n|binding-associated region:1818-2001 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14980 uniprotkb:P63096 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0096"(pull down) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-618699 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 - - - comment:Interaction between numa1 and gnai1 requires gpsm2.|stimulant:Interaction between numa1 and gpsm2 stimulated by gnai1. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/13 2014/10/16 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 intact-crc:9B522071AB5EFCD0|rigid:SSNJ5yxwtDuPWuJiAYJ0U7YWZRY false tag:n-n|binding-associated region:1818-2001 his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14980 uniprotkb:P81274 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0096"(pull down) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-618699 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - comment:Interaction between numa1 and gnai1 requires gpsm2.|stimulant:Interaction between numa1 and gpsm2 stimulated by gnai1. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/13 2014/10/16 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:9B522071AB5EFCD0|rigid:SSNJ5yxwtDuPWuJiAYJ0U7YWZRY false tag:n-n|binding-associated region:1818-2001 his tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P63096 uniprotkb:P81274 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-618721 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - - taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/07/13 2014/10/16 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:084E77B01A649BD8|rigid:SSNJ5yxwtDuPWuJiAYJ0U7YWZRY false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P63096 uniprotkb:Q14980 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-618721 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - - taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/07/13 2014/10/16 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:084E77B01A649BD8|rigid:SSNJ5yxwtDuPWuJiAYJ0U7YWZRY false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P63096 uniprotkb:P81274 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618729 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - - taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2005/07/13 2014/10/16 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:131402B87C28A3BE|rigid:SSNJ5yxwtDuPWuJiAYJ0U7YWZRY false yellow fluorescent protein tag:c-c - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P63096 uniprotkb:Q14980 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618729 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - - taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2005/07/13 2014/10/16 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:131402B87C28A3BE|rigid:SSNJ5yxwtDuPWuJiAYJ0U7YWZRY false yellow fluorescent protein tag:c-c - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P81274 uniprotkb:Q14980 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - - taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:C5CF2273D3C177D3|rigid:TEm26hi2OIDot9VFNuwSn01IiMk false yellow fluorescent protein tag:n-n - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P81274 uniprotkb:P81274 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0018"(two hybrid) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:48ECC2A06A62DEFF|rigid:Cj2BJksszoXByruHgAedm3gru3o false binding-associated region:483-684(IPR003109)|tag:n-n binding-associated region:8-380(IPR011717)|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NH88 uniprotkb:Q14980 intact:EBI-618766 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:q9nh88_drome(display_long)|uniprotkb:pins(gene name)|psi-mi:pins(display_short)|uniprotkb:raps(gene name synonym)|uniprotkb:CG5692(orf name) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Du et al. (2004) pubmed:15537540 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|flybase:FBgn0040080 ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/13 2014/10/16 rogid:JhO052t41AYbFRYt2WKrHD99WJo7227 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:8F9659AADD4B59E7|rigid:6Ou9+ifwOzC6iSNl9uH1AWtDpE8 false binding-associated region:1-376(IPR011990)|tag:n-n binding-associated region:1818-1930|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81274 uniprotkb:Q14980 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2644177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:444E643880F15916|rigid:TEm26hi2OIDot9VFNuwSn01IiMk false binding-associated region:8-380(IPR011717)|tag:n-n binding-associated region:1818-1930|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NH88 uniprotkb:P81274 intact:EBI-618766 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:q9nh88_drome(display_long)|uniprotkb:pins(gene name)|psi-mi:pins(display_short)|uniprotkb:raps(gene name synonym)|uniprotkb:CG5692(orf name) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0018"(two hybrid) Du et al. (2004) pubmed:15537540 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2644191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|flybase:FBgn0040080 ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/13 2014/10/16 rogid:JhO052t41AYbFRYt2WKrHD99WJo7227 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:4AC829B59D6F9AB8|rigid:E+y8HkzlOMq+UELuxJKNZ0yevLQ false binding-associated region:462-658(IPR003109)|tag:n-n binding-associated region:8-380(IPR011717)|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NH88 uniprotkb:Q9NH88 intact:EBI-618766 intact:EBI-618766 psi-mi:q9nh88_drome(display_long)|uniprotkb:pins(gene name)|psi-mi:pins(display_short)|uniprotkb:raps(gene name synonym)|uniprotkb:CG5692(orf name) psi-mi:q9nh88_drome(display_long)|uniprotkb:pins(gene name)|psi-mi:pins(display_short)|uniprotkb:raps(gene name synonym)|uniprotkb:CG5692(orf name) psi-mi:"MI:0018"(two hybrid) Du et al. (2004) pubmed:15537540 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2644239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|flybase:FBgn0040080 go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0055059"(asymmetric neuroblast division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|flybase:FBgn0040080 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/13 2014/10/16 rogid:JhO052t41AYbFRYt2WKrHD99WJo7227 rogid:JhO052t41AYbFRYt2WKrHD99WJo7227 intact-crc:F99CE5D9D423705F|rigid:E8xM3Ff7+rGTXE3HzpTP7A1l2Vo false binding-associated region:1-376(IPR011990)|tag:n-n binding-associated region:462-658(IPR003109)|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81274 uniprotkb:P81274 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0096"(pull down) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - inhibition:"by numa1(1818-2001) and gnai1." taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:08A54126FE1FF42A|rigid:Cj2BJksszoXByruHgAedm3gru3o false binding-associated region:483-684(IPR003109)|tag:n-n glutathione s tranferase tag:n-n|binding-associated region:8-380(IPR011717) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P81274 uniprotkb:Q14980 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0096"(pull down) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-618880 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:57313673841B5690|rigid:TEm26hi2OIDot9VFNuwSn01IiMk false glutathione s tranferase tag:n-n|binding-associated region:8-380 tag:n-n|binding-associated region:1818-2001 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P81274 uniprotkb:P81274 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-618898 - - psi-mi:"MI:0503"(self) psi-mi:"MI:0503"(self) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - figure legend:Figs. 5A, 5B|inhibition:"by gst-numa1(1818-1985) and his-gnai1, and by proteinase k." taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/13 2021/07/12 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:8A6113245CE113EE|rigid:xRY1wfzFJFa6kc+Q4XsQwyVxFyk false tag:c-c|yellow fluorescent protein tag:n-n|binding-associated region:8-617 tag:c-c|yellow fluorescent protein tag:n-n|binding-associated region:8-617 - 0 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P81274 uniprotkb:P81274 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-618911 - - psi-mi:"MI:0503"(self) psi-mi:"MI:0503"(self) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - figure legend:Fig. 5C|inhibition:by HA-numa1 and myc-gnai1. taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2005/07/13 2021/07/12 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:DCD79B80967F4C92|rigid:xRY1wfzFJFa6kc+Q4XsQwyVxFyk false yellow fluorescent protein tag:n-n|binding-associated region:8-617|tag:c-c yellow fluorescent protein tag:n-n|binding-associated region:8-617|tag:c-c - 0 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P81274 uniprotkb:P81274 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0096"(pull down) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-621869 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:FC11241F2C018D75|rigid:Cj2BJksszoXByruHgAedm3gru3o false yellow fluorescent protein tag:n-n|binding-associated region:483-684|tag:?-? tag:n-n|binding-associated region:8-380 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81274 uniprotkb:P81274 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0096"(pull down) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-621885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:DFB2EABF4779C61E|rigid:Cj2BJksszoXByruHgAedm3gru3o false binding-associated region:361-684(IPR003109)|tag:n-n binding-associated region:483-684|yellow fluorescent protein tag:n-n|tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81274 uniprotkb:P81274 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:"MI:0018"(two hybrid) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-624047 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 intact-crc:AC084220BAAA369F|rigid:TEm26hi2OIDot9VFNuwSn01IiMk false binding-associated region:8-135|tag:n-n binding-associated region:483-684|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81274 uniprotkb:Q14980 intact:EBI-618655|uniprotkb:Q5T1N8|ensembl:ENSP00000264126|ensembl:ENSP00000385510|ensembl:ENSP00000392138|ensembl:ENSP00000496104|ensembl:ENSP00000496756|ensembl:ENSP00000502178|uniprotkb:Q8N0Z5|uniprotkb:Q6IBL7 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:gpsm2_human(display_long)|uniprotkb:GPSM2(gene name)|psi-mi:GPSM2(display_short)|uniprotkb:LGN(gene name synonym)|uniprotkb:Mosaic protein LGN(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Du et al. (2004) pubmed:15537540 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-624047 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121957(gene)|ensembl:ENST00000264126(transcript)|ensembl:ENST00000406462(transcript)|ensembl:ENST00000446797(transcript)|ensembl:ENST00000642355(transcript)|ensembl:ENST00000645164(transcript)|ensembl:ENST00000676184(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:P81274|rcsb pdb:3SF4|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:5A6C|rcsb pdb:6HC2|reactome:R-HSA-418594|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_037428.3|refseq:NP_001307967.1|refseq:NP_001307968.1|refseq:XP_011539603.1|refseq:XP_011539604.1|refseq:XP_016856586.1|refseq:XP_016856587.1|dip:DIP-399N ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/13 2014/10/16 rogid:qQOgAYWYhHlMg4d8HsqCxcNqnNg9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:AC084220BAAA369F|rigid:TEm26hi2OIDot9VFNuwSn01IiMk false binding-associated region:8-135|tag:n-n tag:n-n|binding-associated region:1818-1930 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)