#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11274 uniprotkb:Q5T2W1 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|ensembl:ENSP00000342143|ensembl:ENSP00000394485|uniprotkb:B4DPB9|uniprotkb:E7EU02 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358079|mint:MINT-69529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207421(identity) refseq:NP_001188254.1|refseq:NP_002605.2|ensembl:ENSG00000174827(gene)|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|ensembl:ENST00000344770(transcript)|ensembl:ENST00000417171(transcript)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|refseq:NP_001188255.1|refseq:XP_016856953.1|mint:MINT-1207426(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/14 2014/10/16 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606 intact-crc:33F0693AA29554A9|rigid:/VDPS8OJftQmp9AFhJSJ7wb7A7w false - binding-associated region:9-87(MINT-1207427)|glutathione s tranferase tag:?-?(MINT-1207430) - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T2W1 uniprotkb:P11274 intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|ensembl:ENSP00000342143|ensembl:ENSP00000394485|uniprotkb:B4DPB9|uniprotkb:E7EU02 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0096"(pull down) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358145|mint:MINT-69533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001188254.1|refseq:NP_002605.2|ensembl:ENSG00000174827(gene)|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|ensembl:ENST00000344770(transcript)|ensembl:ENST00000417171(transcript)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|refseq:NP_001188255.1|refseq:XP_016856953.1|mint:MINT-1207303(identity) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207294(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2F|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/14 2014/10/16 rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 intact-crc:4BF7F1B84B5BBCF9|rigid:/VDPS8OJftQmp9AFhJSJ7wb7A7w false glutathione s tranferase tag:?-?(MINT-1207307)|binding-associated region:9-87(MINT-1207304) tag:?-?(MINT-1207297)|mutation decreasing interaction:1269-1271(MINT-1207295) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P11274 uniprotkb:Q5T2W1 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|ensembl:ENSP00000342143|ensembl:ENSP00000394485|uniprotkb:B4DPB9|uniprotkb:E7EU02 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358126|mint:MINT-69531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207458(identity) refseq:NP_001188254.1|refseq:NP_002605.2|ensembl:ENSG00000174827(gene)|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|ensembl:ENST00000344770(transcript)|ensembl:ENST00000417171(transcript)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|refseq:NP_001188255.1|refseq:XP_016856953.1|mint:MINT-1207463(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/14 2014/10/16 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606 intact-crc:FA1F72DEFE3943F1|rigid:/VDPS8OJftQmp9AFhJSJ7wb7A7w false - binding-associated region:9-87(MINT-1207464)|glutathione s tranferase tag:?-?(MINT-1207467) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11274 uniprotkb:P13569 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-349854|uniprotkb:Q20BG8|uniprotkb:Q20BH2|uniprotkb:Q2I0A1|uniprotkb:Q2I102|ensembl:ENSP00000003084 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:cftr_human(display_long)|uniprotkb:CFTR(gene name)|psi-mi:CFTR(display_short)|uniprotkb:ABCC7(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7358194|mint:MINT-69537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207628(identity) refseq:NP_000483.3|reactome:R-HSA-8856828|reactome:R-HSA-9013406|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|ensembl:ENSG00000001626(gene)|ensembl:ENST00000003084(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|rcsb pdb:6O1V|rcsb pdb:6O2P|rcsb pdb:6UK1|rcsb pdb:6WBS|reactome:R-HSA-382556|reactome:R-HSA-5627083|reactome:R-HSA-5678895|reactome:R-HSA-5689880|mint:P13569|rcsb pdb:1NBD|rcsb pdb:1XMI|rcsb pdb:1XMJ|rcsb pdb:2BBO|rcsb pdb:2BBS|rcsb pdb:2BBT|rcsb pdb:2LOB|rcsb pdb:2PZE|rcsb pdb:2PZF|rcsb pdb:2PZG|rcsb pdb:3GD7|rcsb pdb:3ISW|rcsb pdb:4WZ6|rcsb pdb:5D2D|rcsb pdb:5D3E|rcsb pdb:5D3F|rcsb pdb:5TF7|rcsb pdb:5TF8|rcsb pdb:5TFA|rcsb pdb:5TFB|rcsb pdb:5TFC|rcsb pdb:5TFD|rcsb pdb:5TFF|rcsb pdb:5TFG|rcsb pdb:5TFI|rcsb pdb:5TFJ|rcsb pdb:5TGK|rcsb pdb:5UAK|rcsb pdb:6GJQ|rcsb pdb:6GJS|rcsb pdb:6GJU|rcsb pdb:6GK4|rcsb pdb:6GKD|rcsb pdb:6HEP|rcsb pdb:6MSM|reactome:R-HSA-8856825|dip:DIP-32788N|mint:MINT-1207633(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/11/14 2014/10/16 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:iuEu3sctRkxQlQYP4BVxV/u4DaA9606 intact-crc:D965E63BCA403FE4|rigid:9qPvjWpkTkTjvaw3ESYYxhcTEIs false - - - - psi-mi:"MI:0709"(polyclonal antibody immunostaining) psi-mi:"MI:0708"(monoclonal antibody immunostaining) uniprotkb:O96018 uniprotkb:P11274 intact:EBI-6115839|uniprotkb:O60483|uniprotkb:Q9UPZ2|intact:EBI-28977865|ensembl:ENSP00000315136 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:apba3_human(display_long)|uniprotkb:APBA3(gene name)|psi-mi:APBA3(display_short)|uniprotkb:MINT3(gene name synonym)|uniprotkb:X11L2(gene name synonym)|uniprotkb:Adapter protein X11gamma(gene name synonym)|uniprotkb:Neuron-specific X11L2 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 3(gene name synonym) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7358205|mint:MINT-69544 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000315136|refseq:NP_004877.1|ensembl:ENSG00000011132(gene)|ensembl:ENST00000316757(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030531|interpro:IPR036034|rcsb pdb:2YT7|rcsb pdb:2YT8|rcsb pdb:5UWS|reactome:R-HSA-6794361|mint:MINT-1207342(identity) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207337(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/11/14 2014/10/16 rogid:9XKJCGIewG6Lx84WB+IkWXcDj3E9606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 intact-crc:5E85205D8C220578|rigid:CZ1+zTV4nBVgczRYWq0dKGxZizs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P11274 uniprotkb:Q00610 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7358332|mint:MINT-69536 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207353(identity) ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424|mint:MINT-1207358(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/11/14 2014/10/16 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:043F6CC9CEE8A35A|rigid:53EDAE+X/5oOAM4KtmplZvKDMOA false - - - - psi-mi:"MI:0709"(polyclonal antibody immunostaining) psi-mi:"MI:0708"(monoclonal antibody immunostaining) uniprotkb:P53618 uniprotkb:P11274 intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7358320|mint:MINT-69535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N|mint:MINT-1207498(identity) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207493(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/11/14 2014/10/16 rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 intact-crc:AA93B5714B308767|rigid:UYpo1Uo2BJFUPk5ztWOfGRpiWsQ false - - - - psi-mi:"MI:0708"(monoclonal antibody immunostaining) psi-mi:"MI:0709"(polyclonal antibody immunostaining) uniprotkb:P11274 uniprotkb:O96018 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-6115839|uniprotkb:O60483|uniprotkb:Q9UPZ2|intact:EBI-28977865|ensembl:ENSP00000315136 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:apba3_human(display_long)|uniprotkb:APBA3(gene name)|psi-mi:APBA3(display_short)|uniprotkb:MINT3(gene name synonym)|uniprotkb:X11L2(gene name synonym)|uniprotkb:Adapter protein X11gamma(gene name synonym)|uniprotkb:Neuron-specific X11L2 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7358359|mint:MINT-69545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207404(identity) ensembl:ENSP00000315136|refseq:NP_004877.1|ensembl:ENSG00000011132(gene)|ensembl:ENST00000316757(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030531|interpro:IPR036034|rcsb pdb:2YT7|rcsb pdb:2YT8|rcsb pdb:5UWS|reactome:R-HSA-6794361|mint:MINT-1207411(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/11/14 2014/10/16 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:9XKJCGIewG6Lx84WB+IkWXcDj3E9606 intact-crc:BDB1091AE0B080D8|rigid:CZ1+zTV4nBVgczRYWq0dKGxZizs false tag:?-?(MINT-1207405) tag:?-?(MINT-1207412) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P11274 uniprotkb:Q5T2W1 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|ensembl:ENSP00000342143|ensembl:ENSP00000394485|uniprotkb:B4DPB9|uniprotkb:E7EU02 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358384|mint:MINT-69532 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207369(identity) refseq:NP_001188254.1|refseq:NP_002605.2|ensembl:ENSG00000174827(gene)|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|ensembl:ENST00000344770(transcript)|ensembl:ENST00000417171(transcript)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|refseq:NP_001188255.1|refseq:XP_016856953.1|mint:MINT-1207374(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21) - 2005/11/14 2014/10/16 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606 intact-crc:4710F54B42796C42|rigid:/VDPS8OJftQmp9AFhJSJ7wb7A7w false - flag tag:?-?(MINT-1207375) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O96018 uniprotkb:P11274 intact:EBI-6115839|uniprotkb:O60483|uniprotkb:Q9UPZ2|intact:EBI-28977865|ensembl:ENSP00000315136 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:apba3_human(display_long)|uniprotkb:APBA3(gene name)|psi-mi:APBA3(display_short)|uniprotkb:MINT3(gene name synonym)|uniprotkb:X11L2(gene name synonym)|uniprotkb:Adapter protein X11gamma(gene name synonym)|uniprotkb:Neuron-specific X11L2 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 3(gene name synonym) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0049"(filter binding) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358406|mint:MINT-69538 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000315136|refseq:NP_004877.1|ensembl:ENSG00000011132(gene)|ensembl:ENST00000316757(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030531|interpro:IPR036034|rcsb pdb:2YT7|rcsb pdb:2YT8|rcsb pdb:5UWS|reactome:R-HSA-6794361|mint:MINT-1207386(identity) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207394(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/14 2014/10/16 rogid:9XKJCGIewG6Lx84WB+IkWXcDj3E9606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 intact-crc:F7D5C13690397500|rigid:CZ1+zTV4nBVgczRYWq0dKGxZizs false binding-associated region:394-478(MINT-1207387) tag:?-?(MINT-1207395) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9UDY2 uniprotkb:P11274 intact:EBI-1042602|uniprotkb:Q15883|uniprotkb:Q5VXL0|uniprotkb:Q8N756|uniprotkb:Q8NI14|uniprotkb:Q99839|uniprotkb:Q9UDY0|uniprotkb:Q9UDY1|uniprotkb:A2A3H9|uniprotkb:Q5VXL1|intact:EBI-10989219|ensembl:ENSP00000366453|uniprotkb:B7Z2R8|uniprotkb:B7Z7T6|uniprotkb:F5H301|uniprotkb:F5H886 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:zo2_human(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:X104(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)|uniprotkb:ZO2(gene name synonym) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0049"(filter binding) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358479|mint:MINT-69540 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163886.1|refseq:NP_001163887.1|refseq:NP_004808.2|refseq:XP_011517508.1|refseq:XP_011517509.1|refseq:XP_011517510.1|refseq:XP_011517511.1|ensembl:ENSG00000119139(gene)|ensembl:ENST00000377245(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035598|interpro:IPR036028|interpro:IPR036034|mint:Q9UDY2|rcsb pdb:2OSG|rcsb pdb:3E17|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:MINT-1207613(identity) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207618(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/14 2014/10/16 rogid:iN/EF8QWKtekoj5eON764eKAdpg9606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 intact-crc:983EE56F393C38AA|rigid:M884BJYYrAmLCDu6UDwM4XcP4lc false - tag:?-?(MINT-1207619) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O14908 uniprotkb:P11274 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0049"(filter binding) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358464|mint:MINT-69539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N|mint:MINT-1207506(identity) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207511(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/14 2014/10/16 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 intact-crc:26166309D311B9D1|rigid:jaWgHJCMn22BIyaIaPRjHqSBsPo false - tag:?-?(MINT-1207512) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O14924 uniprotkb:P11274 intact:EBI-7358493|intact:MINT-154790|uniprotkb:B1AQ31|uniprotkb:O14923|uniprotkb:B1AQ32|uniprotkb:O14922|uniprotkb:O75338|uniprotkb:O43510|uniprotkb:B1AQ30|uniprotkb:E7EMN9|uniprotkb:Q147X0|uniprotkb:Q8WX95|ensembl:ENSP00000338509|ensembl:ENSP00000339381|uniprotkb:B7Z764 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:rgs12_human(display_long)|uniprotkb:RGS12(gene name)|psi-mi:RGS12(display_short) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0049"(filter binding) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358534|mint:MINT-69542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011511845.1|refseq:NP_002917.1|refseq:NP_937872.1|refseq:NP_937870.1|refseq:XP_016864018.1|refseq:XP_016864020.1|refseq:XP_016864021.1|refseq:XP_016864022.1|ensembl:ENSG00000159788(gene)|ensembl:ENST00000336727(transcript)|ensembl:ENST00000344733(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003109(GoLoco)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066|interpro:IPR029071|interpro:IPR036034|interpro:IPR036305|interpro:IPR037880|rcsb pdb:2EBZ|rcsb pdb:2KV8|reactome:R-HSA-418594|refseq:XP_006713968.1|refseq:XP_006713969.1|refseq:XP_006713970.1|mint:MINT-1207521(identity) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207526(identity) - function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/14 2014/10/16 rogid:86ann2gpd8ZhURj5bP5EhPwz9Fo9606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 intact-crc:97988599ADB47A47|rigid:zJiqXGhd1bsL6hfca8uLcxl+oJs false - tag:?-?(MINT-1207527) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P11274 uniprotkb:Q5T2W1 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|ensembl:ENSP00000342143|ensembl:ENSP00000394485|uniprotkb:B4DPB9|uniprotkb:E7EU02 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358558|mint:MINT-69530 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207441(identity) refseq:NP_001188254.1|refseq:NP_002605.2|ensembl:ENSG00000174827(gene)|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|ensembl:ENST00000344770(transcript)|ensembl:ENST00000417171(transcript)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|refseq:NP_001188255.1|refseq:XP_016856953.1|mint:MINT-1207448(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21) - 2005/11/14 2014/10/16 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606 intact-crc:ABF8B81400403EA9|rigid:/VDPS8OJftQmp9AFhJSJ7wb7A7w false glutathione s tranferase tag:?-?(MINT-1207442) flag tag:?-?(MINT-1207449) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11274 uniprotkb:O96018 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-6115839|uniprotkb:O60483|uniprotkb:Q9UPZ2|intact:EBI-28977865|ensembl:ENSP00000315136 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:apba3_human(display_long)|uniprotkb:APBA3(gene name)|psi-mi:APBA3(display_short)|uniprotkb:MINT3(gene name synonym)|uniprotkb:X11L2(gene name synonym)|uniprotkb:Adapter protein X11gamma(gene name synonym)|uniprotkb:Neuron-specific X11L2 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358588|mint:MINT-69541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207725(identity) ensembl:ENSP00000315136|refseq:NP_004877.1|ensembl:ENSG00000011132(gene)|ensembl:ENST00000316757(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030531|interpro:IPR036034|rcsb pdb:2YT7|rcsb pdb:2YT8|rcsb pdb:5UWS|reactome:R-HSA-6794361|mint:MINT-1207734(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21) - 2005/11/14 2014/10/16 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:9XKJCGIewG6Lx84WB+IkWXcDj3E9606 intact-crc:5174EF17160B7CB6|rigid:CZ1+zTV4nBVgczRYWq0dKGxZizs false mutation decreasing interaction:1269-1271(MINT-1207726)|glutathione s tranferase tag:?-?(MINT-1207728) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:O96018 uniprotkb:P11274 intact:EBI-6115839|uniprotkb:O60483|uniprotkb:Q9UPZ2|intact:EBI-28977865|ensembl:ENSP00000315136 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:apba3_human(display_long)|uniprotkb:APBA3(gene name)|psi-mi:APBA3(display_short)|uniprotkb:MINT3(gene name synonym)|uniprotkb:X11L2(gene name synonym)|uniprotkb:Adapter protein X11gamma(gene name synonym)|uniprotkb:Neuron-specific X11L2 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 3(gene name synonym) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7358688|mint:MINT-69543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000315136|refseq:NP_004877.1|ensembl:ENSG00000011132(gene)|ensembl:ENST00000316757(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030531|interpro:IPR036034|rcsb pdb:2YT7|rcsb pdb:2YT8|rcsb pdb:5UWS|reactome:R-HSA-6794361|mint:MINT-1207485(identity) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207478(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/11/14 2014/10/16 rogid:9XKJCGIewG6Lx84WB+IkWXcDj3E9606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 intact-crc:8FD4D08BA75B5A34|rigid:CZ1+zTV4nBVgczRYWq0dKGxZizs false - glutathione s tranferase tag:?-?(MINT-1207479) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11274 uniprotkb:P20020 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043 psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Malmberg et al. (2004) pubmed:15494376|mint:MINT-5217253 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7358710|mint:MINT-69534 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2|mint:MINT-1207710(identity) refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|mint:MINT-1207717(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21) - 2005/11/14 2018/09/18 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:kCpUNLYDF38hciXj32D8rXbXULg9606 intact-crc:33E990EC2D4D575C|rigid:X9Rmk2tChVnQQBxw8hN9J7M6XOc false tag:?-?(MINT-1207711) - - - psi-mi:"MI:0709"(polyclonal antibody immunostaining) psi-mi:"MI:0708"(monoclonal antibody immunostaining)