#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NYB0	uniprotkb:Q14676	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764884	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473	-	-	-	complex-properties:"From text \"The same RAP1 complex was able to form even in the presence of ethidium bromide, suggesting that the interactions between the various components were not mediated through DNA (data not shown).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606	intact-crc:9CA801E10C6C513E|rigid:+7eUj8Hvkmlewl0VYeJXDXPYdqU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NYB0	uniprotkb:Q92878-3	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-495527	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:q92878-3(display_long)|uniprotkb:RAD50-3(isoform synonym)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764884	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	intact:EBI-495494(rad50_human)	-	-	-	complex-properties:"From text \"The same RAP1 complex was able to form even in the presence of ethidium bromide, suggesting that the interactions between the various components were not mediated through DNA (data not shown).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:Hk1AsC/INqeqrGtNXxGJE0Fxqak9606	intact-crc:9CA801E10C6C513E|rigid:+7eUj8Hvkmlewl0VYeJXDXPYdqU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NYB0	uniprotkb:P08107	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764884	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487	-	-	-	complex-properties:"From text \"The same RAP1 complex was able to form even in the presence of ethidium bromide, suggesting that the interactions between the various components were not mediated through DNA (data not shown).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	intact-crc:9CA801E10C6C513E|rigid:+7eUj8Hvkmlewl0VYeJXDXPYdqU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NYB0	uniprotkb:P12956	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764884	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	-	-	-	complex-properties:"From text \"The same RAP1 complex was able to form even in the presence of ethidium bromide, suggesting that the interactions between the various components were not mediated through DNA (data not shown).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	intact-crc:9CA801E10C6C513E|rigid:+7eUj8Hvkmlewl0VYeJXDXPYdqU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NYB0	uniprotkb:Q15554	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764884	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	-	-	-	complex-properties:"From text \"The same RAP1 complex was able to form even in the presence of ethidium bromide, suggesting that the interactions between the various components were not mediated through DNA (data not shown).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	intact-crc:9CA801E10C6C513E|rigid:+7eUj8Hvkmlewl0VYeJXDXPYdqU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NYB0	uniprotkb:P13010	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764884	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695	-	-	-	complex-properties:"From text \"The same RAP1 complex was able to form even in the presence of ethidium bromide, suggesting that the interactions between the various components were not mediated through DNA (data not shown).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	intact-crc:9CA801E10C6C513E|rigid:+7eUj8Hvkmlewl0VYeJXDXPYdqU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NYB0	uniprotkb:Q9BSI4	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-717399|uniprotkb:Q9H904|uniprotkb:Q9UHC2|uniprotkb:B3W5Q7|ensembl:ENSP00000267415|ensembl:ENSP00000495019	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:tinf2_human(display_long)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764884	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	refseq:NP_001092744.1|refseq:NP_036593.2|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|ensembl:ENSG00000284915(gene)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:1904356"(regulation of telomere maintenance via telomere lengthening)|ensembl:ENST00000267415(transcript)|interpro:IPR029400|interpro:IPR039098|mint:Q9BSI4|rcsb pdb:3BQO|rcsb pdb:3BU8|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|ensembl:ENST00000646576(transcript)|go:"GO:0000781"(chromosome, telomeric region)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|go:"GO:0000783"(nuclear telomere cap complex)|reactome:R-HSA-171319|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0010370"(perinucleolar chromocenter)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0016233"(telomere capping)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0032202"(telomere assembly)|ensembl:ENSG00000092330(gene)|dip:DIP-29413N	-	-	-	complex-properties:"From text \"The same RAP1 complex was able to form even in the presence of ethidium bromide, suggesting that the interactions between the various components were not mediated through DNA (data not shown).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:l/sNYfQWtGUBmGDKBRAluwdaiag9606	intact-crc:9CA801E10C6C513E|rigid:+7eUj8Hvkmlewl0VYeJXDXPYdqU	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NUX5	uniprotkb:Q9BSI4-3	intact:EBI-752420|uniprotkb:O95018|uniprotkb:Q9H662|uniprotkb:Q9NW19|uniprotkb:Q9UG95|uniprotkb:Q5MJ36|ensembl:ENSP00000350249|ensembl:ENSP00000499290|ensembl:ENSP00000499476|ensembl:ENSP00000499546|ensembl:ENSP00000499635	intact:EBI-717418	psi-mi:pote1_human(display_long)|uniprotkb:POT1-like telomere end-binding protein(gene name synonym)|uniprotkb:POT1(gene name)|psi-mi:POT1(display_short)	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764923	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001036059.1|refseq:NP_056265.2|refseq:XP_006715980.1|dip:DIP-29610N|ensembl:ENSG00000128513(gene)|ensembl:ENST00000357628(transcript)|ensembl:ENST00000653241(transcript)|ensembl:ENST00000655761(transcript)|ensembl:ENST00000664366(transcript)|ensembl:ENST00000668382(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0032202"(telomere assembly)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060383"(positive regulation of DNA strand elongation)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1905774"(regulation of DNA helicase activity)|go:"GO:1905776"(positive regulation of DNA helicase activity)|go:"GO:1990955"(G-rich single-stranded DNA binding)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR032042|rcsb pdb:1XJV|rcsb pdb:3KJO|rcsb pdb:3KJP|rcsb pdb:5H65|rcsb pdb:5UN7|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	intact:EBI-717399(tinf2_human)	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:h/UEb6TNSNHVB4S0YRgS2oA4ydQ9606	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	intact-crc:A630B973E4267104|rigid:2xIZOKUS3NfllMGiFvV3hPtNvms	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NUX5	uniprotkb:Q15554	intact:EBI-752420|uniprotkb:O95018|uniprotkb:Q9H662|uniprotkb:Q9NW19|uniprotkb:Q9UG95|uniprotkb:Q5MJ36|ensembl:ENSP00000350249|ensembl:ENSP00000499290|ensembl:ENSP00000499476|ensembl:ENSP00000499546|ensembl:ENSP00000499635	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	psi-mi:pote1_human(display_long)|uniprotkb:POT1-like telomere end-binding protein(gene name synonym)|uniprotkb:POT1(gene name)|psi-mi:POT1(display_short)	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764923	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001036059.1|refseq:NP_056265.2|refseq:XP_006715980.1|dip:DIP-29610N|ensembl:ENSG00000128513(gene)|ensembl:ENST00000357628(transcript)|ensembl:ENST00000653241(transcript)|ensembl:ENST00000655761(transcript)|ensembl:ENST00000664366(transcript)|ensembl:ENST00000668382(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0032202"(telomere assembly)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060383"(positive regulation of DNA strand elongation)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1905774"(regulation of DNA helicase activity)|go:"GO:1905776"(positive regulation of DNA helicase activity)|go:"GO:1990955"(G-rich single-stranded DNA binding)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR032042|rcsb pdb:1XJV|rcsb pdb:3KJO|rcsb pdb:3KJP|rcsb pdb:5H65|rcsb pdb:5UN7|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:h/UEb6TNSNHVB4S0YRgS2oA4ydQ9606	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	intact-crc:A630B973E4267104|rigid:2xIZOKUS3NfllMGiFvV3hPtNvms	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96AP0	uniprotkb:Q9NUX5	intact:EBI-717666|uniprotkb:Q562H5|uniprotkb:Q9H8F9|uniprotkb:A0A0C4DGT6|ensembl:ENSP00000478084	intact:EBI-752420|uniprotkb:O95018|uniprotkb:Q9H662|uniprotkb:Q9NW19|uniprotkb:Q9UG95|uniprotkb:Q5MJ36|ensembl:ENSP00000350249|ensembl:ENSP00000499290|ensembl:ENSP00000499476|ensembl:ENSP00000499546|ensembl:ENSP00000499635	psi-mi:acd_human(display_long)|uniprotkb:POT1 and TIN2-interacting protein(gene name synonym)|uniprotkb:ACD(gene name)|psi-mi:ACD(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:PTOP(gene name synonym)|uniprotkb:TINT1(gene name synonym)|uniprotkb:TPP1(gene name synonym)	psi-mi:pote1_human(display_long)|uniprotkb:POT1-like telomere end-binding protein(gene name synonym)|uniprotkb:POT1(gene name)|psi-mi:POT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764927	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075955.1|refseq:NP_001075956.1|refseq:NP_075065.2|go:"GO:0035282"(segmentation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060381"(positive regulation of single-stranded telomeric DNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070200"(establishment of protein localization to telomere)|interpro:IPR019437|interpro:IPR028631|rcsb pdb:2I46|rcsb pdb:5H65|rcsb pdb:5I2X|rcsb pdb:5I2Y|rcsb pdb:5UN7|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|ensembl:ENSG00000102977(gene)|ensembl:ENST00000620761(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0001655"(urogenital system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032202"(telomere assembly)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|dip:DIP-29611N	refseq:NP_001036059.1|refseq:NP_056265.2|refseq:XP_006715980.1|dip:DIP-29610N|ensembl:ENSG00000128513(gene)|ensembl:ENST00000357628(transcript)|ensembl:ENST00000653241(transcript)|ensembl:ENST00000655761(transcript)|ensembl:ENST00000664366(transcript)|ensembl:ENST00000668382(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0032202"(telomere assembly)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060383"(positive regulation of DNA strand elongation)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1905774"(regulation of DNA helicase activity)|go:"GO:1905776"(positive regulation of DNA helicase activity)|go:"GO:1990955"(G-rich single-stranded DNA binding)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR032042|rcsb pdb:1XJV|rcsb pdb:3KJO|rcsb pdb:3KJP|rcsb pdb:5H65|rcsb pdb:5UN7|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2019/09/20	rogid:Z073GMd5V0shLNtElKVeCwr5fCA9606	rogid:h/UEb6TNSNHVB4S0YRgS2oA4ydQ9606	intact-crc:270CF3180BAD7C87|rigid:nKb17XcZe0SfLNVWG20h8+5ZLsI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96AP0	uniprotkb:Q9BSI4-3	intact:EBI-717666|uniprotkb:Q562H5|uniprotkb:Q9H8F9|uniprotkb:A0A0C4DGT6|ensembl:ENSP00000478084	intact:EBI-717418	psi-mi:acd_human(display_long)|uniprotkb:POT1 and TIN2-interacting protein(gene name synonym)|uniprotkb:ACD(gene name)|psi-mi:ACD(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:PTOP(gene name synonym)|uniprotkb:TINT1(gene name synonym)|uniprotkb:TPP1(gene name synonym)	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764927	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075955.1|refseq:NP_001075956.1|refseq:NP_075065.2|go:"GO:0035282"(segmentation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060381"(positive regulation of single-stranded telomeric DNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070200"(establishment of protein localization to telomere)|interpro:IPR019437|interpro:IPR028631|rcsb pdb:2I46|rcsb pdb:5H65|rcsb pdb:5I2X|rcsb pdb:5I2Y|rcsb pdb:5UN7|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|ensembl:ENSG00000102977(gene)|ensembl:ENST00000620761(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0001655"(urogenital system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032202"(telomere assembly)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|dip:DIP-29611N	intact:EBI-717399(tinf2_human)	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2019/09/20	rogid:Z073GMd5V0shLNtElKVeCwr5fCA9606	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	intact-crc:270CF3180BAD7C87|rigid:nKb17XcZe0SfLNVWG20h8+5ZLsI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96AP0	uniprotkb:Q15554	intact:EBI-717666|uniprotkb:Q562H5|uniprotkb:Q9H8F9|uniprotkb:A0A0C4DGT6|ensembl:ENSP00000478084	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	psi-mi:acd_human(display_long)|uniprotkb:POT1 and TIN2-interacting protein(gene name synonym)|uniprotkb:ACD(gene name)|psi-mi:ACD(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:PTOP(gene name synonym)|uniprotkb:TINT1(gene name synonym)|uniprotkb:TPP1(gene name synonym)	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764927	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075955.1|refseq:NP_001075956.1|refseq:NP_075065.2|go:"GO:0035282"(segmentation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060381"(positive regulation of single-stranded telomeric DNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070200"(establishment of protein localization to telomere)|interpro:IPR019437|interpro:IPR028631|rcsb pdb:2I46|rcsb pdb:5H65|rcsb pdb:5I2X|rcsb pdb:5I2Y|rcsb pdb:5UN7|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|ensembl:ENSG00000102977(gene)|ensembl:ENST00000620761(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0001655"(urogenital system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032202"(telomere assembly)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|dip:DIP-29611N	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2019/09/20	rogid:Z073GMd5V0shLNtElKVeCwr5fCA9606	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	intact-crc:270CF3180BAD7C87|rigid:nKb17XcZe0SfLNVWG20h8+5ZLsI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BSI4-3	uniprotkb:Q15554	intact:EBI-717418	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764957	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-717399(tinf2_human)	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	intact-crc:FE94D3F326E1887E|rigid:2xIZOKUS3NfllMGiFvV3hPtNvms	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BSI4-3	uniprotkb:Q9NUX5	intact:EBI-717418	intact:EBI-752420|uniprotkb:O95018|uniprotkb:Q9H662|uniprotkb:Q9NW19|uniprotkb:Q9UG95|uniprotkb:Q5MJ36|ensembl:ENSP00000350249|ensembl:ENSP00000499290|ensembl:ENSP00000499476|ensembl:ENSP00000499546|ensembl:ENSP00000499635	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:pote1_human(display_long)|uniprotkb:POT1-like telomere end-binding protein(gene name synonym)|uniprotkb:POT1(gene name)|psi-mi:POT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764957	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-717399(tinf2_human)	refseq:NP_001036059.1|refseq:NP_056265.2|refseq:XP_006715980.1|dip:DIP-29610N|ensembl:ENSG00000128513(gene)|ensembl:ENST00000357628(transcript)|ensembl:ENST00000653241(transcript)|ensembl:ENST00000655761(transcript)|ensembl:ENST00000664366(transcript)|ensembl:ENST00000668382(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0032202"(telomere assembly)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060383"(positive regulation of DNA strand elongation)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1905774"(regulation of DNA helicase activity)|go:"GO:1905776"(positive regulation of DNA helicase activity)|go:"GO:1990955"(G-rich single-stranded DNA binding)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR032042|rcsb pdb:1XJV|rcsb pdb:3KJO|rcsb pdb:3KJP|rcsb pdb:5H65|rcsb pdb:5UN7|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	rogid:h/UEb6TNSNHVB4S0YRgS2oA4ydQ9606	intact-crc:FE94D3F326E1887E|rigid:2xIZOKUS3NfllMGiFvV3hPtNvms	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NYB0	uniprotkb:Q9BSI4-3	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-717418	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764961	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	intact:EBI-717399(tinf2_human)	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	intact-crc:9B54D36098A625B8|rigid:kxJZ+TYYXsD+Ta2bFgVo6+gDuFY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NYB0	uniprotkb:Q15554	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764961	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	intact-crc:9B54D36098A625B8|rigid:kxJZ+TYYXsD+Ta2bFgVo6+gDuFY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NYB0	uniprotkb:Q9NUX5	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-752420|uniprotkb:O95018|uniprotkb:Q9H662|uniprotkb:Q9NW19|uniprotkb:Q9UG95|uniprotkb:Q5MJ36|ensembl:ENSP00000350249|ensembl:ENSP00000499290|ensembl:ENSP00000499476|ensembl:ENSP00000499546|ensembl:ENSP00000499635	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:pote1_human(display_long)|uniprotkb:POT1-like telomere end-binding protein(gene name synonym)|uniprotkb:POT1(gene name)|psi-mi:POT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764961	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	refseq:NP_001036059.1|refseq:NP_056265.2|refseq:XP_006715980.1|dip:DIP-29610N|ensembl:ENSG00000128513(gene)|ensembl:ENST00000357628(transcript)|ensembl:ENST00000653241(transcript)|ensembl:ENST00000655761(transcript)|ensembl:ENST00000664366(transcript)|ensembl:ENST00000668382(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0032202"(telomere assembly)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060383"(positive regulation of DNA strand elongation)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1905774"(regulation of DNA helicase activity)|go:"GO:1905776"(positive regulation of DNA helicase activity)|go:"GO:1990955"(G-rich single-stranded DNA binding)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR032042|rcsb pdb:1XJV|rcsb pdb:3KJO|rcsb pdb:3KJP|rcsb pdb:5H65|rcsb pdb:5UN7|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:h/UEb6TNSNHVB4S0YRgS2oA4ydQ9606	intact-crc:9B54D36098A625B8|rigid:kxJZ+TYYXsD+Ta2bFgVo6+gDuFY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15554	uniprotkb:Q9BSI4-3	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	intact:EBI-717418	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764966	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	intact:EBI-717399(tinf2_human)	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	intact-crc:8CBBFF868B19629D|rigid:2xIZOKUS3NfllMGiFvV3hPtNvms	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15554	uniprotkb:Q9NUX5	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	intact:EBI-752420|uniprotkb:O95018|uniprotkb:Q9H662|uniprotkb:Q9NW19|uniprotkb:Q9UG95|uniprotkb:Q5MJ36|ensembl:ENSP00000350249|ensembl:ENSP00000499290|ensembl:ENSP00000499476|ensembl:ENSP00000499546|ensembl:ENSP00000499635	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:pote1_human(display_long)|uniprotkb:POT1-like telomere end-binding protein(gene name synonym)|uniprotkb:POT1(gene name)|psi-mi:POT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-764966	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	refseq:NP_001036059.1|refseq:NP_056265.2|refseq:XP_006715980.1|dip:DIP-29610N|ensembl:ENSG00000128513(gene)|ensembl:ENST00000357628(transcript)|ensembl:ENST00000653241(transcript)|ensembl:ENST00000655761(transcript)|ensembl:ENST00000664366(transcript)|ensembl:ENST00000668382(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0032202"(telomere assembly)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060383"(positive regulation of DNA strand elongation)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1905774"(regulation of DNA helicase activity)|go:"GO:1905776"(positive regulation of DNA helicase activity)|go:"GO:1990955"(G-rich single-stranded DNA binding)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR032042|rcsb pdb:1XJV|rcsb pdb:3KJO|rcsb pdb:3KJP|rcsb pdb:5H65|rcsb pdb:5UN7|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	rogid:h/UEb6TNSNHVB4S0YRgS2oA4ydQ9606	intact-crc:8CBBFF868B19629D|rigid:2xIZOKUS3NfllMGiFvV3hPtNvms	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NYB0	uniprotkb:Q15554	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765072	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	intact-crc:212314A21E2DAAC9|rigid:K8yijdKH43Vy4CMlL1tzGxOJMPk	false	flag tag:?-?|binding-associated region:1-290	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NYB0	uniprotkb:Q9BSI4-3	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	intact:EBI-717418	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765072	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	intact:EBI-717399(tinf2_human)	-	-	-	-	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	intact-crc:212314A21E2DAAC9|rigid:K8yijdKH43Vy4CMlL1tzGxOJMPk	false	flag tag:?-?|binding-associated region:1-290	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96AP0	uniprotkb:Q9NUX5	intact:EBI-717666|uniprotkb:Q562H5|uniprotkb:Q9H8F9|uniprotkb:A0A0C4DGT6|ensembl:ENSP00000478084	intact:EBI-752420|uniprotkb:O95018|uniprotkb:Q9H662|uniprotkb:Q9NW19|uniprotkb:Q9UG95|uniprotkb:Q5MJ36|ensembl:ENSP00000350249|ensembl:ENSP00000499290|ensembl:ENSP00000499476|ensembl:ENSP00000499546|ensembl:ENSP00000499635	psi-mi:acd_human(display_long)|uniprotkb:POT1 and TIN2-interacting protein(gene name synonym)|uniprotkb:ACD(gene name)|psi-mi:ACD(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:PTOP(gene name synonym)|uniprotkb:TINT1(gene name synonym)|uniprotkb:TPP1(gene name synonym)	psi-mi:pote1_human(display_long)|uniprotkb:POT1-like telomere end-binding protein(gene name synonym)|uniprotkb:POT1(gene name)|psi-mi:POT1(display_short)	psi-mi:"MI:0071"(molecular sieving)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765004	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075955.1|refseq:NP_001075956.1|refseq:NP_075065.2|go:"GO:0035282"(segmentation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060381"(positive regulation of single-stranded telomeric DNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070200"(establishment of protein localization to telomere)|interpro:IPR019437|interpro:IPR028631|rcsb pdb:2I46|rcsb pdb:5H65|rcsb pdb:5I2X|rcsb pdb:5I2Y|rcsb pdb:5UN7|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|ensembl:ENSG00000102977(gene)|ensembl:ENST00000620761(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0001655"(urogenital system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032202"(telomere assembly)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|dip:DIP-29611N	refseq:NP_001036059.1|refseq:NP_056265.2|refseq:XP_006715980.1|dip:DIP-29610N|ensembl:ENSG00000128513(gene)|ensembl:ENST00000357628(transcript)|ensembl:ENST00000653241(transcript)|ensembl:ENST00000655761(transcript)|ensembl:ENST00000664366(transcript)|ensembl:ENST00000668382(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0032202"(telomere assembly)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060383"(positive regulation of DNA strand elongation)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1905774"(regulation of DNA helicase activity)|go:"GO:1905776"(positive regulation of DNA helicase activity)|go:"GO:1990955"(G-rich single-stranded DNA binding)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR032042|rcsb pdb:1XJV|rcsb pdb:3KJO|rcsb pdb:3KJP|rcsb pdb:5H65|rcsb pdb:5UN7|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	-	-	-	caution:"Authors note that \"It should be noted that some of the telomeric proteins (e.g. RAP1 and TRF2) were also co-eluted at lower molecular weight fractions. Therefore, there may be other telomere complexes in addition to the telosome (i.e. the protein complex detected by gel filtration desciribed here).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2019/09/20	rogid:Z073GMd5V0shLNtElKVeCwr5fCA9606	rogid:h/UEb6TNSNHVB4S0YRgS2oA4ydQ9606	intact-crc:6A7C8A8494F89E91|rigid:fbeKYUFqHcp3czCKbEzzv4HGoww	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96AP0	uniprotkb:Q9BSI4-3	intact:EBI-717666|uniprotkb:Q562H5|uniprotkb:Q9H8F9|uniprotkb:A0A0C4DGT6|ensembl:ENSP00000478084	intact:EBI-717418	psi-mi:acd_human(display_long)|uniprotkb:POT1 and TIN2-interacting protein(gene name synonym)|uniprotkb:ACD(gene name)|psi-mi:ACD(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:PTOP(gene name synonym)|uniprotkb:TINT1(gene name synonym)|uniprotkb:TPP1(gene name synonym)	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765004	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075955.1|refseq:NP_001075956.1|refseq:NP_075065.2|go:"GO:0035282"(segmentation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060381"(positive regulation of single-stranded telomeric DNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070200"(establishment of protein localization to telomere)|interpro:IPR019437|interpro:IPR028631|rcsb pdb:2I46|rcsb pdb:5H65|rcsb pdb:5I2X|rcsb pdb:5I2Y|rcsb pdb:5UN7|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|ensembl:ENSG00000102977(gene)|ensembl:ENST00000620761(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0001655"(urogenital system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032202"(telomere assembly)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|dip:DIP-29611N	intact:EBI-717399(tinf2_human)	-	-	-	caution:"Authors note that \"It should be noted that some of the telomeric proteins (e.g. RAP1 and TRF2) were also co-eluted at lower molecular weight fractions. Therefore, there may be other telomere complexes in addition to the telosome (i.e. the protein complex detected by gel filtration desciribed here).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2019/09/20	rogid:Z073GMd5V0shLNtElKVeCwr5fCA9606	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	intact-crc:6A7C8A8494F89E91|rigid:fbeKYUFqHcp3czCKbEzzv4HGoww	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96AP0	uniprotkb:Q9NYB0	intact:EBI-717666|uniprotkb:Q562H5|uniprotkb:Q9H8F9|uniprotkb:A0A0C4DGT6|ensembl:ENSP00000478084	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	psi-mi:acd_human(display_long)|uniprotkb:POT1 and TIN2-interacting protein(gene name synonym)|uniprotkb:ACD(gene name)|psi-mi:ACD(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:PTOP(gene name synonym)|uniprotkb:TINT1(gene name synonym)|uniprotkb:TPP1(gene name synonym)	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765004	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075955.1|refseq:NP_001075956.1|refseq:NP_075065.2|go:"GO:0035282"(segmentation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060381"(positive regulation of single-stranded telomeric DNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070200"(establishment of protein localization to telomere)|interpro:IPR019437|interpro:IPR028631|rcsb pdb:2I46|rcsb pdb:5H65|rcsb pdb:5I2X|rcsb pdb:5I2Y|rcsb pdb:5UN7|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|ensembl:ENSG00000102977(gene)|ensembl:ENST00000620761(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0001655"(urogenital system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032202"(telomere assembly)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|dip:DIP-29611N	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	-	-	-	caution:"Authors note that \"It should be noted that some of the telomeric proteins (e.g. RAP1 and TRF2) were also co-eluted at lower molecular weight fractions. Therefore, there may be other telomere complexes in addition to the telosome (i.e. the protein complex detected by gel filtration desciribed here).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2019/09/20	rogid:Z073GMd5V0shLNtElKVeCwr5fCA9606	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	intact-crc:6A7C8A8494F89E91|rigid:fbeKYUFqHcp3czCKbEzzv4HGoww	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96AP0	uniprotkb:P54274	intact:EBI-717666|uniprotkb:Q562H5|uniprotkb:Q9H8F9|uniprotkb:A0A0C4DGT6|ensembl:ENSP00000478084	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	psi-mi:acd_human(display_long)|uniprotkb:POT1 and TIN2-interacting protein(gene name synonym)|uniprotkb:ACD(gene name)|psi-mi:ACD(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:PTOP(gene name synonym)|uniprotkb:TINT1(gene name synonym)|uniprotkb:TPP1(gene name synonym)	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765004	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075955.1|refseq:NP_001075956.1|refseq:NP_075065.2|go:"GO:0035282"(segmentation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060381"(positive regulation of single-stranded telomeric DNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070200"(establishment of protein localization to telomere)|interpro:IPR019437|interpro:IPR028631|rcsb pdb:2I46|rcsb pdb:5H65|rcsb pdb:5I2X|rcsb pdb:5I2Y|rcsb pdb:5UN7|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|ensembl:ENSG00000102977(gene)|ensembl:ENST00000620761(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0001655"(urogenital system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032202"(telomere assembly)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|dip:DIP-29611N	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	-	-	-	caution:"Authors note that \"It should be noted that some of the telomeric proteins (e.g. RAP1 and TRF2) were also co-eluted at lower molecular weight fractions. Therefore, there may be other telomere complexes in addition to the telosome (i.e. the protein complex detected by gel filtration desciribed here).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2019/09/20	rogid:Z073GMd5V0shLNtElKVeCwr5fCA9606	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	intact-crc:6A7C8A8494F89E91|rigid:fbeKYUFqHcp3czCKbEzzv4HGoww	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96AP0	uniprotkb:Q15554	intact:EBI-717666|uniprotkb:Q562H5|uniprotkb:Q9H8F9|uniprotkb:A0A0C4DGT6|ensembl:ENSP00000478084	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	psi-mi:acd_human(display_long)|uniprotkb:POT1 and TIN2-interacting protein(gene name synonym)|uniprotkb:ACD(gene name)|psi-mi:ACD(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:PTOP(gene name synonym)|uniprotkb:TINT1(gene name synonym)|uniprotkb:TPP1(gene name synonym)	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765004	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075955.1|refseq:NP_001075956.1|refseq:NP_075065.2|go:"GO:0035282"(segmentation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060381"(positive regulation of single-stranded telomeric DNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070200"(establishment of protein localization to telomere)|interpro:IPR019437|interpro:IPR028631|rcsb pdb:2I46|rcsb pdb:5H65|rcsb pdb:5I2X|rcsb pdb:5I2Y|rcsb pdb:5UN7|rcsb pdb:5XYF|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|ensembl:ENSG00000102977(gene)|ensembl:ENST00000620761(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0001655"(urogenital system development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032202"(telomere assembly)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|dip:DIP-29611N	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	-	-	-	caution:"Authors note that \"It should be noted that some of the telomeric proteins (e.g. RAP1 and TRF2) were also co-eluted at lower molecular weight fractions. Therefore, there may be other telomere complexes in addition to the telosome (i.e. the protein complex detected by gel filtration desciribed here).\""	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/07	2019/09/20	rogid:Z073GMd5V0shLNtElKVeCwr5fCA9606	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	intact-crc:6A7C8A8494F89E91|rigid:fbeKYUFqHcp3czCKbEzzv4HGoww	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54274	uniprotkb:Q9BSI4-3	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	intact:EBI-717418	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	intact:EBI-717399(tinf2_human)	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/07	2014/10/16	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	intact-crc:38228480A9E874ED|rigid:kLiFcUJZ9uhZOYPbKI4CBJmkNRk	false	glutathione s tranferase tag:?-?	radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15554	uniprotkb:Q9BSI4-3	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	intact:EBI-717418	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	intact:EBI-717399(tinf2_human)	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/07	2014/10/16	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	intact-crc:EDF69DF1118027EF|rigid:+SSlv/e4nDYTSf4Md9HNVVcx83Y	false	glutathione s tranferase tag:?-?	radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BSI4-3	uniprotkb:Q9NYB0	intact:EBI-717418	intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-717399(tinf2_human)	ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/07	2014/10/16	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606	intact-crc:14B8A7BDC3F662FD|rigid:6DT1Oz55UE3zd81lXDOEGORpSio	false	radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BSI4-3	uniprotkb:P54274	intact:EBI-717418	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-717399(tinf2_human)	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	-	-	-	complex-properties:Endogenous TRF1, TRF2, and TIN2 exhibited punctate staining patterns,  characteristic of telomeric proteins	taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line)	-	2005/12/07	2014/10/16	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	intact-crc:BDBD9E67E8F4A9BA|rigid:XuzBCbj1KLKjOObWPh0eSsBNYLQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BSI4-3	uniprotkb:Q15554	intact:EBI-717418	intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651	psi-mi:q9bsi4-3(display_long)|uniprotkb:TINF2(gene name)|psi-mi:TINF2(display_short)|uniprotkb:TIN2(gene name synonym)|uniprotkb:TRF1-interacting nuclear protein 2(gene name synonym)	psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2004)	pubmed:15383534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-765157	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-717399(tinf2_human)	go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N	-	-	-	complex-properties:Endogenous TRF1, TRF2, and TIN2 exhibited punctate staining patterns,  characteristic of telomeric proteins	taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line)	-	2005/12/07	2014/10/16	rogid:Qx0Yh/0XT6GCmLshOBizhmR6mfo9606	rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606	intact-crc:BDBD9E67E8F4A9BA|rigid:XuzBCbj1KLKjOObWPh0eSsBNYLQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)