#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5HYK7 uniprotkb:O43184 intact:EBI-2563437|uniprotkb:Q8N5E7|uniprotkb:Q9UFC8|uniprotkb:Q86XB3|uniprotkb:Q08EK1|uniprotkb:B7Z296|uniprotkb:Q5U3B8|uniprotkb:Q32N10|intact:EBI-28974104|ensembl:ENSP00000302913|ensembl:ENSP00000386848 intact:EBI-2625825|uniprotkb:O60470|uniprotkb:Q5JRP0|uniprotkb:Q5JRP1|uniprotkb:Q6P9E3|uniprotkb:Q6UWB0|ensembl:ENSP00000357668 psi-mi:sh319_human(display_long)|uniprotkb:ADAM-binding protein Eve-1(gene name synonym)|uniprotkb:EEN-binding protein(gene name synonym)|uniprotkb:SH3D19(gene name)|psi-mi:SH3D19(display_short) psi-mi:ada12_human(display_long)|uniprotkb:ADAM12(gene name)|psi-mi:ADAM12(display_short)|uniprotkb:MLTN(gene name synonym)|uniprotkb:Meltrin-alpha(gene name synonym)|uniprotkb:UNQ346/PRO545(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tanaka et al. (2004) pubmed:15280379|mint:MINT-5217133 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7280467|mint:MINT-56611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009555.3|refseq:NP_001122395.1|refseq:NP_001122396.1|refseq:NP_001230278.1|ensembl:ENSP00000302913|ensembl:ENSP00000386848|ensembl:ENST00000409598|ensembl:ENSP00000387030|ensembl:ENST00000427414|ensembl:ENSP00000415694|ensembl:ENST00000514152|ensembl:ENSP00000423449|refseq:XP_011529948.1|refseq:XP_011529951.1|ensembl:ENSG00000109686(gene)|ensembl:ENST00000304527(transcript)|ensembl:ENST00000409252(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR001452(Src homology-3)|interpro:IPR035834|interpro:IPR035835|interpro:IPR036028|reactome:R-HSA-432722|refseq:XP_005262824.1|refseq:XP_016863268.1|refseq:XP_016863270.1|refseq:XP_016863271.1|refseq:XP_016863272.1|mint:MINT-1203613(identity) refseq:NP_003465.3|refseq:NP_067673.2|refseq:NP_001275903.1|refseq:NP_001275904.1|ensembl:ENSG00000148848(gene)|ensembl:ENST00000368679(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|mint:O43184|reactome:R-HSA-177929|reactome:R-HSA-8941237|mint:MINT-1203609(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3B|comment:homomint|comment:mint taxid:9606(human)|taxid:9606(Homo sapiens) - 2005/03/14 2014/10/16 rogid:FHHjKjFAjdTiMJVEUVD9geriCn09606 rogid:BxY61EDGsWcXVsb7i8+zzf7Q12c9606 intact-crc:07367F39B93AC064|rigid:b7r6lbydw5FTbcmU9Y544J18t4g false tag:?-?(MINT-1203614) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5HYK7 uniprotkb:O43184 intact:EBI-2563437|uniprotkb:Q8N5E7|uniprotkb:Q9UFC8|uniprotkb:Q86XB3|uniprotkb:Q08EK1|uniprotkb:B7Z296|uniprotkb:Q5U3B8|uniprotkb:Q32N10|intact:EBI-28974104|ensembl:ENSP00000302913|ensembl:ENSP00000386848 intact:EBI-2625825|uniprotkb:O60470|uniprotkb:Q5JRP0|uniprotkb:Q5JRP1|uniprotkb:Q6P9E3|uniprotkb:Q6UWB0|ensembl:ENSP00000357668 psi-mi:sh319_human(display_long)|uniprotkb:ADAM-binding protein Eve-1(gene name synonym)|uniprotkb:EEN-binding protein(gene name synonym)|uniprotkb:SH3D19(gene name)|psi-mi:SH3D19(display_short) psi-mi:ada12_human(display_long)|uniprotkb:ADAM12(gene name)|psi-mi:ADAM12(display_short)|uniprotkb:MLTN(gene name synonym)|uniprotkb:Meltrin-alpha(gene name synonym)|uniprotkb:UNQ346/PRO545(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tanaka et al. (2004) pubmed:15280379|mint:MINT-5217133 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7280481|mint:MINT-56612 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009555.3|refseq:NP_001122395.1|refseq:NP_001122396.1|refseq:NP_001230278.1|ensembl:ENSP00000302913|ensembl:ENSP00000386848|ensembl:ENST00000409598|ensembl:ENSP00000387030|ensembl:ENST00000427414|ensembl:ENSP00000415694|ensembl:ENST00000514152|ensembl:ENSP00000423449|refseq:XP_011529948.1|refseq:XP_011529951.1|ensembl:ENSG00000109686(gene)|ensembl:ENST00000304527(transcript)|ensembl:ENST00000409252(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR001452(Src homology-3)|interpro:IPR035834|interpro:IPR035835|interpro:IPR036028|reactome:R-HSA-432722|refseq:XP_005262824.1|refseq:XP_016863268.1|refseq:XP_016863270.1|refseq:XP_016863271.1|refseq:XP_016863272.1|mint:MINT-1203602(identity) refseq:NP_003465.3|refseq:NP_067673.2|refseq:NP_001275903.1|refseq:NP_001275904.1|ensembl:ENSG00000148848(gene)|ensembl:ENST00000368679(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|mint:O43184|reactome:R-HSA-177929|reactome:R-HSA-8941237|mint:MINT-1203596(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:homomint|comment:mint taxid:9606(human)|taxid:9606(Homo sapiens) - 2005/03/14 2014/10/16 rogid:FHHjKjFAjdTiMJVEUVD9geriCn09606 rogid:BxY61EDGsWcXVsb7i8+zzf7Q12c9606 intact-crc:4037497790A84156|rigid:b7r6lbydw5FTbcmU9Y544J18t4g false - tag:?-?(MINT-1203597) - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43184 uniprotkb:Q5HYK7 intact:EBI-2625825|uniprotkb:O60470|uniprotkb:Q5JRP0|uniprotkb:Q5JRP1|uniprotkb:Q6P9E3|uniprotkb:Q6UWB0|ensembl:ENSP00000357668 intact:EBI-2563437|uniprotkb:Q8N5E7|uniprotkb:Q9UFC8|uniprotkb:Q86XB3|uniprotkb:Q08EK1|uniprotkb:B7Z296|uniprotkb:Q5U3B8|uniprotkb:Q32N10|intact:EBI-28974104|ensembl:ENSP00000302913|ensembl:ENSP00000386848 psi-mi:ada12_human(display_long)|uniprotkb:ADAM12(gene name)|psi-mi:ADAM12(display_short)|uniprotkb:MLTN(gene name synonym)|uniprotkb:Meltrin-alpha(gene name synonym)|uniprotkb:UNQ346/PRO545(orf name) psi-mi:sh319_human(display_long)|uniprotkb:ADAM-binding protein Eve-1(gene name synonym)|uniprotkb:EEN-binding protein(gene name synonym)|uniprotkb:SH3D19(gene name)|psi-mi:SH3D19(display_short) psi-mi:"MI:0428"(imaging technique) Tanaka et al. (2004) pubmed:15280379|mint:MINT-5217133 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7280523|mint:MINT-56614 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003465.3|refseq:NP_067673.2|refseq:NP_001275903.1|refseq:NP_001275904.1|ensembl:ENSG00000148848(gene)|ensembl:ENST00000368679(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|mint:O43184|reactome:R-HSA-177929|reactome:R-HSA-8941237|mint:MINT-1203624(identity) refseq:NP_001009555.3|refseq:NP_001122395.1|refseq:NP_001122396.1|refseq:NP_001230278.1|ensembl:ENSP00000302913|ensembl:ENSP00000386848|ensembl:ENST00000409598|ensembl:ENSP00000387030|ensembl:ENST00000427414|ensembl:ENSP00000415694|ensembl:ENST00000514152|ensembl:ENSP00000423449|refseq:XP_011529948.1|refseq:XP_011529951.1|ensembl:ENSG00000109686(gene)|ensembl:ENST00000304527(transcript)|ensembl:ENST00000409252(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR001452(Src homology-3)|interpro:IPR035834|interpro:IPR035835|interpro:IPR036028|reactome:R-HSA-432722|refseq:XP_005262824.1|refseq:XP_016863268.1|refseq:XP_016863270.1|refseq:XP_016863271.1|refseq:XP_016863272.1|mint:MINT-1203631(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6|comment:homomint|comment:mint taxid:9606(human)|taxid:9606(Homo sapiens) - 2005/03/14 2014/10/16 rogid:BxY61EDGsWcXVsb7i8+zzf7Q12c9606 rogid:FHHjKjFAjdTiMJVEUVD9geriCn09606 intact-crc:9371349A5280AA47|rigid:b7r6lbydw5FTbcmU9Y544J18t4g false tag:?-?(MINT-1203625) tag:?-?(MINT-1203632) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O43184 uniprotkb:Q5HYK7 intact:EBI-2625825|uniprotkb:O60470|uniprotkb:Q5JRP0|uniprotkb:Q5JRP1|uniprotkb:Q6P9E3|uniprotkb:Q6UWB0|ensembl:ENSP00000357668 intact:EBI-2563437|uniprotkb:Q8N5E7|uniprotkb:Q9UFC8|uniprotkb:Q86XB3|uniprotkb:Q08EK1|uniprotkb:B7Z296|uniprotkb:Q5U3B8|uniprotkb:Q32N10|intact:EBI-28974104|ensembl:ENSP00000302913|ensembl:ENSP00000386848 psi-mi:ada12_human(display_long)|uniprotkb:ADAM12(gene name)|psi-mi:ADAM12(display_short)|uniprotkb:MLTN(gene name synonym)|uniprotkb:Meltrin-alpha(gene name synonym)|uniprotkb:UNQ346/PRO545(orf name) psi-mi:sh319_human(display_long)|uniprotkb:ADAM-binding protein Eve-1(gene name synonym)|uniprotkb:EEN-binding protein(gene name synonym)|uniprotkb:SH3D19(gene name)|psi-mi:SH3D19(display_short) psi-mi:"MI:0096"(pull down) Tanaka et al. (2004) pubmed:15280379|mint:MINT-5217133 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7280595|mint:MINT-56613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003465.3|refseq:NP_067673.2|refseq:NP_001275903.1|refseq:NP_001275904.1|ensembl:ENSG00000148848(gene)|ensembl:ENST00000368679(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|mint:O43184|reactome:R-HSA-177929|reactome:R-HSA-8941237|mint:MINT-1203643(identity) refseq:NP_001009555.3|refseq:NP_001122395.1|refseq:NP_001122396.1|refseq:NP_001230278.1|ensembl:ENSP00000302913|ensembl:ENSP00000386848|ensembl:ENST00000409598|ensembl:ENSP00000387030|ensembl:ENST00000427414|ensembl:ENSP00000415694|ensembl:ENST00000514152|ensembl:ENSP00000423449|refseq:XP_011529948.1|refseq:XP_011529951.1|ensembl:ENSG00000109686(gene)|ensembl:ENST00000304527(transcript)|ensembl:ENST00000409252(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR001452(Src homology-3)|interpro:IPR035834|interpro:IPR035835|interpro:IPR036028|reactome:R-HSA-432722|refseq:XP_005262824.1|refseq:XP_016863268.1|refseq:XP_016863270.1|refseq:XP_016863271.1|refseq:XP_016863272.1|mint:MINT-1203651(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4B|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/14 2014/10/16 rogid:BxY61EDGsWcXVsb7i8+zzf7Q12c9606 rogid:FHHjKjFAjdTiMJVEUVD9geriCn09606 intact-crc:08CFF5F033DD3D52|rigid:b7r6lbydw5FTbcmU9Y544J18t4g false binding-associated region:829-840(MINT-1203644)|tag:?-?(MINT-1203646) tag:?-?(MINT-1203652) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)