#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O14512 uniprotkb:O60504 intact:EBI-1539606|uniprotkb:A2VCU2|uniprotkb:Q0IJ63|ensembl:ENSP00000480736|ensembl:ENSP00000499750 intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4 psi-mi:socs7_human(display_long)|uniprotkb:SOCS7(gene name)|psi-mi:SOCS7(display_short)|uniprotkb:NAP4(gene name synonym)|uniprotkb:SOCS6(gene name synonym)|uniprotkb:Nck, Ash and phospholipase C gamma-binding protein(gene name synonym)|uniprotkb:Nck-associated protein 4(gene name synonym) psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martens et al. (2004) pubmed:15242778|mint:MINT-5217101 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271375|mint:MINT-56620 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055413.1|ensembl:ENSG00000274211(gene)|ensembl:ENSG00000274229(gene)|ensembl:ENST00000615473(transcript)|ensembl:ENST00000665913(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028423|interpro:IPR035866|interpro:IPR036036|interpro:IPR036860|interpro:IPR037346|mint:MINT-1202535(identity) ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|mint:MINT-1202541(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:Splicing variant betha of SCAM did not co-precipitated with SOCS-7|comment:homomint|comment:mint taxid:10090(mouse-nih 3t3-l1)|taxid:10090(Mus musculus) - 2005/03/15 2014/10/16 rogid:MbBKOLby106g9tDOvy4FhIG6lgY9606 rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606 intact-crc:E3FDED2C861B136F|rigid:eBAqKD6bImqgr+qHoKmFLO9FsOM false tag:?-?(MINT-1202536) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:O60504-1 uniprotkb:O14512 intact:EBI-1222953|ensembl:ENSP00000240123|intact:EBI-8565375|intact:MINT-262503|intact:EBI-7905024|intact:EBI-7271420 intact:EBI-1539606|uniprotkb:A2VCU2|uniprotkb:Q0IJ63|ensembl:ENSP00000480736|ensembl:ENSP00000499750 psi-mi:o60504-1(display_long)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym) psi-mi:socs7_human(display_long)|uniprotkb:SOCS7(gene name)|psi-mi:SOCS7(display_short)|uniprotkb:NAP4(gene name synonym)|uniprotkb:SOCS6(gene name synonym)|uniprotkb:Nck, Ash and phospholipase C gamma-binding protein(gene name synonym)|uniprotkb:Nck-associated protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Martens et al. (2004) pubmed:15242778|mint:MINT-5217101 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7271430|mint:MINT-56615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|intact:EBI-741237(vinex_human)|mint:MINT-1202557(identity) refseq:NP_055413.1|ensembl:ENSG00000274211(gene)|ensembl:ENSG00000274229(gene)|ensembl:ENST00000615473(transcript)|ensembl:ENST00000665913(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028423|interpro:IPR035866|interpro:IPR036036|interpro:IPR036860|interpro:IPR037346|mint:MINT-1202551(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/03/15 2014/10/16 rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606 rogid:MbBKOLby106g9tDOvy4FhIG6lgY9606 intact-crc:38540DFB7A4C6A80|rigid:eBAqKD6bImqgr+qHoKmFLO9FsOM false tag:?-?(MINT-1202558) tag:?-?(MINT-1202552) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14512 uniprotkb:O60504 intact:EBI-1539606|uniprotkb:A2VCU2|uniprotkb:Q0IJ63|ensembl:ENSP00000480736|ensembl:ENSP00000499750 intact:EBI-741237|ensembl:ENSP00000240123|uniprotkb:Q5BJE4|uniprotkb:Q6NX54|uniprotkb:Q9UQE4|intact:EBI-1222937|uniprotkb:Q96FY4 psi-mi:socs7_human(display_long)|uniprotkb:SOCS7(gene name)|psi-mi:SOCS7(display_short)|uniprotkb:NAP4(gene name synonym)|uniprotkb:SOCS6(gene name synonym)|uniprotkb:Nck, Ash and phospholipase C gamma-binding protein(gene name synonym)|uniprotkb:Nck-associated protein 4(gene name synonym) psi-mi:vinex_human(display_long)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Martens et al. (2004) pubmed:15242778|mint:MINT-5217101 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7271472|mint:MINT-56622 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055413.1|ensembl:ENSG00000274211(gene)|ensembl:ENSG00000274229(gene)|ensembl:ENST00000615473(transcript)|ensembl:ENST00000665913(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028423|interpro:IPR035866|interpro:IPR036036|interpro:IPR036860|interpro:IPR037346|mint:MINT-1202568(identity) ensembl:ENSG00000120896(gene)|ensembl:ENST00000240123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR028510|interpro:IPR035607|interpro:IPR035608|interpro:IPR035609|interpro:IPR036028|mint:O60504|rcsb pdb:2CT3|rcsb pdb:2DLM|rcsb pdb:2NWM|rcsb pdb:2YUP|reactome:R-HSA-445355|refseq:NP_001018003.1|refseq:NP_005766.3|refseq:XP_005273428.1|refseq:XP_016868433.1|refseq:XP_016868434.1|refseq:XP_016868435.1|mint:MINT-1202575(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2005/03/15 2014/10/16 rogid:MbBKOLby106g9tDOvy4FhIG6lgY9606 rogid:Mq3VXduU/1gqfUwliO9sBBOb/Vc9606 intact-crc:495DD6290FBB0D71|rigid:eBAqKD6bImqgr+qHoKmFLO9FsOM false tag:?-?(MINT-1202569) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot)