#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P30305-2 uniprotkb:P31946 intact:EBI-7202104|intact:MINT-124441|ensembl:ENSP00000405972 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:p30305-2(display_long)|uniprotkb:CDC25B(gene name)|psi-mi:CDC25B(display_short)|uniprotkb:CDC25HU2(gene name synonym)|uniprotkb:Dual specificity phosphatase Cdc25B(gene name synonym)|uniprotkb:CDC25B1(isoform synonym) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Uchida et al. (2004) pubmed:15173315|mint:MINT-5217050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7202098|mint:MINT-51064 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1051746(isoform-parent)|ensembl:ENSG00000101224(gene)|ensembl:ENST00000439880(transcript)|mint:MINT-1177643(identity) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-1177649(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/10 2014/10/16 rogid:XqFDJgvkMoF8qT7pt8CUbkh/49g9606 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:7C7FC9168FEF71A8|rigid:T8z3Kq3MyruE4FXARQe9vvb6GhA false tag:?-?(MINT-1177644) tag:?-?(MINT-1177653)|binding-associated region:1-245(MINT-1177650) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30305-2 uniprotkb:P31946 intact:EBI-7202104|intact:MINT-124441|ensembl:ENSP00000405972 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:p30305-2(display_long)|uniprotkb:CDC25B(gene name)|psi-mi:CDC25B(display_short)|uniprotkb:CDC25HU2(gene name synonym)|uniprotkb:Dual specificity phosphatase Cdc25B(gene name synonym)|uniprotkb:CDC25B1(isoform synonym) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Uchida et al. (2004) pubmed:15173315|mint:MINT-5217050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7202131|mint:MINT-51065 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1051746(isoform-parent)|ensembl:ENSG00000101224(gene)|ensembl:ENST00000439880(transcript)|mint:MINT-1177625(identity) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-1177631(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/10 2014/10/16 rogid:XqFDJgvkMoF8qT7pt8CUbkh/49g9606 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:C9DCFB586F1DA37C|rigid:T8z3Kq3MyruE4FXARQe9vvb6GhA false tag:?-?(MINT-1177626) tag:?-?(MINT-1177635)|binding-associated region:1-245(MINT-1177632) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30305-2 uniprotkb:P62258 intact:EBI-7202104|intact:MINT-124441|ensembl:ENSP00000405972 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:p30305-2(display_long)|uniprotkb:CDC25B(gene name)|psi-mi:CDC25B(display_short)|uniprotkb:CDC25HU2(gene name synonym)|uniprotkb:Dual specificity phosphatase Cdc25B(gene name synonym)|uniprotkb:CDC25B1(isoform synonym) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Uchida et al. (2004) pubmed:15173315|mint:MINT-5217050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7202176|mint:MINT-51067 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1051746(isoform-parent)|ensembl:ENSG00000101224(gene)|ensembl:ENST00000439880(transcript)|mint:MINT-1177616(identity) refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447|mint:MINT-1177608(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/10 2014/10/16 rogid:XqFDJgvkMoF8qT7pt8CUbkh/49g9606 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:84612DBBDFCB78B2|rigid:w/yyajd69IoTW/P7e+Uth72Ml+M false tag:?-?(MINT-1177617) tag:?-?(MINT-1177611)|binding-associated region:1-255(MINT-1177609) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30305-2 uniprotkb:P62258 intact:EBI-7202104|intact:MINT-124441|ensembl:ENSP00000405972 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:p30305-2(display_long)|uniprotkb:CDC25B(gene name)|psi-mi:CDC25B(display_short)|uniprotkb:CDC25HU2(gene name synonym)|uniprotkb:Dual specificity phosphatase Cdc25B(gene name synonym)|uniprotkb:CDC25B1(isoform synonym) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Uchida et al. (2004) pubmed:15173315|mint:MINT-5217050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7202154|mint:MINT-51066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1051746(isoform-parent)|ensembl:ENSG00000101224(gene)|ensembl:ENST00000439880(transcript)|mint:MINT-1177669(identity) refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447|mint:MINT-1177661(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/10 2014/10/16 rogid:XqFDJgvkMoF8qT7pt8CUbkh/49g9606 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:120B46DD63AAB5F1|rigid:w/yyajd69IoTW/P7e+Uth72Ml+M false tag:?-?(MINT-1177670) tag:?-?(MINT-1177664)|binding-associated region:1-255(MINT-1177662) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30305-2 uniprotkb:P31947 intact:EBI-7202104|intact:MINT-124441|ensembl:ENSP00000405972 intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316 psi-mi:p30305-2(display_long)|uniprotkb:CDC25B(gene name)|psi-mi:CDC25B(display_short)|uniprotkb:CDC25HU2(gene name synonym)|uniprotkb:Dual specificity phosphatase Cdc25B(gene name synonym)|uniprotkb:CDC25B1(isoform synonym) psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Uchida et al. (2004) pubmed:15173315|mint:MINT-5217050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7202307|mint:MINT-51068 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1051746(isoform-parent)|ensembl:ENSG00000101224(gene)|ensembl:ENST00000439880(transcript)|mint:MINT-1177686(identity) ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N|mint:MINT-1177678(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/10 2014/10/16 rogid:XqFDJgvkMoF8qT7pt8CUbkh/49g9606 rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606 intact-crc:D2A4CBA826A55CAA|rigid:BpwRol8OcQc2TZO1TH7k5X6nm8M false tag:?-?(MINT-1177687) binding-associated region:1-248(MINT-1177679)|tag:?-?(MINT-1177681) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30305-2 uniprotkb:P31947 intact:EBI-7202104|intact:MINT-124441|ensembl:ENSP00000405972 intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316 psi-mi:p30305-2(display_long)|uniprotkb:CDC25B(gene name)|psi-mi:CDC25B(display_short)|uniprotkb:CDC25HU2(gene name synonym)|uniprotkb:Dual specificity phosphatase Cdc25B(gene name synonym)|uniprotkb:CDC25B1(isoform synonym) psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Uchida et al. (2004) pubmed:15173315|mint:MINT-5217050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7202371|mint:MINT-51070 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1051746(isoform-parent)|ensembl:ENSG00000101224(gene)|ensembl:ENST00000439880(transcript)|mint:MINT-1177712(identity) ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N|mint:MINT-1177718(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/10 2014/10/16 rogid:XqFDJgvkMoF8qT7pt8CUbkh/49g9606 rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606 intact-crc:047C2BA826A55E08|rigid:BpwRol8OcQc2TZO1TH7k5X6nm8M false tag:?-?(MINT-1177713) tag:?-?(MINT-1177722)|binding-associated region:1-248(MINT-1177719) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30305 uniprotkb:P31947 intact:EBI-1051746|uniprotkb:O43551|uniprotkb:Q13971|uniprotkb:Q5JX77|uniprotkb:Q6RSS1|uniprotkb:Q9BRA6|uniprotkb:D3DVY1|uniprotkb:D3DVY2|uniprotkb:D3DVY3|uniprotkb:D3DVY4|ensembl:ENSP00000245960 intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316 psi-mi:mpip2_human(display_long)|uniprotkb:Dual specificity phosphatase Cdc25B(gene name synonym)|uniprotkb:CDC25B(gene name)|psi-mi:CDC25B(display_short)|uniprotkb:CDC25HU2(gene name synonym) psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Uchida et al. (2004) pubmed:15173315|mint:MINT-5217050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7202349|mint:MINT-51069 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004349.1|refseq:NP_068658.1|refseq:NP_068659.1|refseq:NP_001274448.1|refseq:NP_001274453.1|ensembl:ENSG00000101224(gene)|ensembl:ENST00000245960(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001556"(oocyte maturation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007144"(female meiosis I)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|mint:P30305|rcsb pdb:1CWR|rcsb pdb:1CWS|rcsb pdb:1CWT|rcsb pdb:1QB0|rcsb pdb:1YM9|rcsb pdb:1YMD|rcsb pdb:1YMK|rcsb pdb:1YML|rcsb pdb:1YS0|rcsb pdb:2A2K|rcsb pdb:2IFD|rcsb pdb:2IFV|rcsb pdb:2UZQ|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:4WH7|rcsb pdb:4WH9|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-8862803|dip:DIP-323N|mint:MINT-1177703(identity) ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N|mint:MINT-1177695(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/10 2014/10/16 rogid:okfbcXrQ0dh/TRk/iKOEf6KDNU49606 rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606 intact-crc:E964363FBF635CCF|rigid:tV5EqESQ80btHo0b+UwpSdhhUsU false tag:?-?(MINT-1177704) tag:?-?(MINT-1177698)|binding-associated region:1-248(MINT-1177696) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30305 uniprotkb:P31946 intact:EBI-1051746|uniprotkb:O43551|uniprotkb:Q13971|uniprotkb:Q5JX77|uniprotkb:Q6RSS1|uniprotkb:Q9BRA6|uniprotkb:D3DVY1|uniprotkb:D3DVY2|uniprotkb:D3DVY3|uniprotkb:D3DVY4|ensembl:ENSP00000245960 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:mpip2_human(display_long)|uniprotkb:Dual specificity phosphatase Cdc25B(gene name synonym)|uniprotkb:CDC25B(gene name)|psi-mi:CDC25B(display_short)|uniprotkb:CDC25HU2(gene name synonym) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Uchida et al. (2004) pubmed:15173315|mint:MINT-5217050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7202403|mint:MINT-8006726 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004349.1|refseq:NP_068658.1|refseq:NP_068659.1|refseq:NP_001274448.1|refseq:NP_001274453.1|ensembl:ENSG00000101224(gene)|ensembl:ENST00000245960(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001556"(oocyte maturation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007144"(female meiosis I)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|mint:P30305|rcsb pdb:1CWR|rcsb pdb:1CWS|rcsb pdb:1CWT|rcsb pdb:1QB0|rcsb pdb:1YM9|rcsb pdb:1YMD|rcsb pdb:1YMK|rcsb pdb:1YML|rcsb pdb:1YS0|rcsb pdb:2A2K|rcsb pdb:2IFD|rcsb pdb:2IFV|rcsb pdb:2UZQ|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:4WH7|rcsb pdb:4WH9|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-8862803|dip:DIP-323N|mint:MINT-8006730(identity)|uniprotkb:P30305(original identifier) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-8006727(identity)|uniprotkb:P31946(original identifier) - - - comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2005/01/10 2014/10/16 rogid:okfbcXrQ0dh/TRk/iKOEf6KDNU49606 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:C7DB1B8CC544F8DB|rigid:q3c84H7VizfWK4J5iQb5C8OweGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)