#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P52188 uniprotkb:Q62915 intact:EBI-704583 intact:EBI-704635 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:cskp_rat(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:62004|refseq:NP_071520.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|rcsb pdb:1RSO|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|reactome:R-RNO-6794361|rcsb pdb:6LNM|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis) - - - comment:"rat Pals2 (Vam-1) and actin-binding LIM protein-1 (ab-LIM) were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:S7T42QMExgUKMZpBQEJNjQeR9ZE10116 intact-crc:ADD0C6F9B00BED31|rigid:bcBiPyQKorqoCrb8suAzhfJ18EA false glutathione s tranferase tag:?-?|sufficient binding region:?-?|necessary binding region:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q792I0 intact:EBI-704583 intact:EBI-704626|ensembl:ENSRNOP00000065941 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:lin7c_rat(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:Lin7c(gene name)|psi-mi:Lin7c(display_short)|uniprotkb:Mals3(gene name synonym)|uniprotkb:Veli3(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:621164|refseq:NP_068623.1|ensembl:ENSRNOG00000045698(gene)|ensembl:ENSRNOT00000073258(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676 - - - comment:"rat Pals2 (Vam-1) and actin-binding LIM protein-1 (ab-LIM) were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:F2rasaJ64Olc9qScN79LJRqsUEE10116 intact-crc:ADD0C6F9B00BED31|rigid:bcBiPyQKorqoCrb8suAzhfJ18EA false glutathione s tranferase tag:?-?|sufficient binding region:?-?|necessary binding region:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q9Z250 intact:EBI-704583 intact:EBI-704603|uniprotkb:Q9Z251 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:lin7a_rat(display_long)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Lin7a(gene name)|psi-mi:Lin7a(display_short)|uniprotkb:Mals1(gene name synonym)|uniprotkb:Veli1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:621256|refseq:NP_445966.1|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0097016"(L27 domain binding) - - - comment:"rat Pals2 (Vam-1) and actin-binding LIM protein-1 (ab-LIM) were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:idN6PywIN4UCisrRHcL+IWuH56M10116 intact-crc:ADD0C6F9B00BED31|rigid:bcBiPyQKorqoCrb8suAzhfJ18EA false glutathione s tranferase tag:?-?|sufficient binding region:?-?|necessary binding region:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q63622 intact:EBI-704583 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034 - - - comment:"rat Pals2 (Vam-1) and actin-binding LIM protein-1 (ab-LIM) were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:ADD0C6F9B00BED31|rigid:bcBiPyQKorqoCrb8suAzhfJ18EA false glutathione s tranferase tag:?-?|sufficient binding region:?-?|necessary binding region:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q62936 intact:EBI-704583 intact:EBI-349596|uniprotkb:P70547|ensembl:ENSRNOP00000003741 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg3_rat(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)|uniprotkb:PSD-95/SAP90-related protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:68423|refseq:NP_113827.1|ensembl:ENSRNOG00000002767(gene)|ensembl:ENSRNOT00000003741(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|mint:Q62936|rcsb pdb:3JXT|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-6794361|reactome:R-RNO-8849932|refseq:XP_006257144.1 - - - comment:"rat Pals2 (Vam-1) and actin-binding LIM protein-1 (ab-LIM) were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:SE5z/dJFoJsSa0HYyz7KOlFDHio10116 intact-crc:ADD0C6F9B00BED31|rigid:bcBiPyQKorqoCrb8suAzhfJ18EA false glutathione s tranferase tag:?-?|sufficient binding region:?-?|necessary binding region:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:P31016 intact:EBI-704583 intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N - - - comment:"rat Pals2 (Vam-1) and actin-binding LIM protein-1 (ab-LIM) were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116 intact-crc:ADD0C6F9B00BED31|rigid:bcBiPyQKorqoCrb8suAzhfJ18EA false glutathione s tranferase tag:?-?|sufficient binding region:?-?|necessary binding region:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q62696 intact:EBI-704583 intact:EBI-389325 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N - - - comment:"rat Pals2 (Vam-1) and actin-binding LIM protein-1 (ab-LIM) were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:ADD0C6F9B00BED31|rigid:bcBiPyQKorqoCrb8suAzhfJ18EA false glutathione s tranferase tag:?-?|sufficient binding region:?-?|necessary binding region:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:O35430 intact:EBI-704583 intact:EBI-704760 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:apba1_rat(display_long)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Apba1(gene name)|psi-mi:Apba1(display_short)|uniprotkb:Mint1(gene name synonym)|uniprotkb:X11(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704679 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:620844|refseq:NP_113967.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR030530|mint:O35430|interpro:IPR036034|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:4DBB|rcsb pdb:6KMH|reactome:R-RNO-212676 - - - comment:"rat Pals2 (Vam-1), actin-binding LIM protein-1 (ab-LIM), alpha dystrobrevin-1, alpha-dystrobrevin-2 and dystrophins proteins were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:ybffWeGU/EFTeYx031rgcwPB2w410116 intact-crc:B48355CAE93E15FD|rigid:UysEUfzWRWvrPtEGV1900VinSWU false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:Q62936 intact:EBI-704583 intact:EBI-349596|uniprotkb:P70547|ensembl:ENSRNOP00000003741 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg3_rat(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)|uniprotkb:PSD-95/SAP90-related protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704679 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:68423|refseq:NP_113827.1|ensembl:ENSRNOG00000002767(gene)|ensembl:ENSRNOT00000003741(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|mint:Q62936|rcsb pdb:3JXT|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-6794361|reactome:R-RNO-8849932|refseq:XP_006257144.1 - - - comment:"rat Pals2 (Vam-1), actin-binding LIM protein-1 (ab-LIM), alpha dystrobrevin-1, alpha-dystrobrevin-2 and dystrophins proteins were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:SE5z/dJFoJsSa0HYyz7KOlFDHio10116 intact-crc:B48355CAE93E15FD|rigid:UysEUfzWRWvrPtEGV1900VinSWU false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:Q62915 intact:EBI-704583 intact:EBI-704635 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:cskp_rat(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704679 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:62004|refseq:NP_071520.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|rcsb pdb:1RSO|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|reactome:R-RNO-6794361|rcsb pdb:6LNM|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis) - - - comment:"rat Pals2 (Vam-1), actin-binding LIM protein-1 (ab-LIM), alpha dystrobrevin-1, alpha-dystrobrevin-2 and dystrophins proteins were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:S7T42QMExgUKMZpBQEJNjQeR9ZE10116 intact-crc:B48355CAE93E15FD|rigid:UysEUfzWRWvrPtEGV1900VinSWU false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:Q792I0 intact:EBI-704583 intact:EBI-704626|ensembl:ENSRNOP00000065941 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:lin7c_rat(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:Lin7c(gene name)|psi-mi:Lin7c(display_short)|uniprotkb:Mals3(gene name synonym)|uniprotkb:Veli3(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704679 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:621164|refseq:NP_068623.1|ensembl:ENSRNOG00000045698(gene)|ensembl:ENSRNOT00000073258(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676 - - - comment:"rat Pals2 (Vam-1), actin-binding LIM protein-1 (ab-LIM), alpha dystrobrevin-1, alpha-dystrobrevin-2 and dystrophins proteins were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:F2rasaJ64Olc9qScN79LJRqsUEE10116 intact-crc:B48355CAE93E15FD|rigid:UysEUfzWRWvrPtEGV1900VinSWU false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:Q9Z250 intact:EBI-704583 intact:EBI-704603|uniprotkb:Q9Z251 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:lin7a_rat(display_long)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Lin7a(gene name)|psi-mi:Lin7a(display_short)|uniprotkb:Mals1(gene name synonym)|uniprotkb:Veli1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704679 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:621256|refseq:NP_445966.1|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0097016"(L27 domain binding) - - - comment:"rat Pals2 (Vam-1), actin-binding LIM protein-1 (ab-LIM), alpha dystrobrevin-1, alpha-dystrobrevin-2 and dystrophins proteins were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:idN6PywIN4UCisrRHcL+IWuH56M10116 intact-crc:B48355CAE93E15FD|rigid:UysEUfzWRWvrPtEGV1900VinSWU false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:Q63622 intact:EBI-704583 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704679 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034 - - - comment:"rat Pals2 (Vam-1), actin-binding LIM protein-1 (ab-LIM), alpha dystrobrevin-1, alpha-dystrobrevin-2 and dystrophins proteins were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:B48355CAE93E15FD|rigid:UysEUfzWRWvrPtEGV1900VinSWU false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:P31016 intact:EBI-704583 intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704679 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N - - - comment:"rat Pals2 (Vam-1), actin-binding LIM protein-1 (ab-LIM), alpha dystrobrevin-1, alpha-dystrobrevin-2 and dystrophins proteins were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116 intact-crc:B48355CAE93E15FD|rigid:UysEUfzWRWvrPtEGV1900VinSWU false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:Q62696 intact:EBI-704583 intact:EBI-389325 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704679 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N - - - comment:"rat Pals2 (Vam-1), actin-binding LIM protein-1 (ab-LIM), alpha dystrobrevin-1, alpha-dystrobrevin-2 and dystrophins proteins were also identified"|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:B48355CAE93E15FD|rigid:UysEUfzWRWvrPtEGV1900VinSWU false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:O35430 intact:EBI-704583 intact:EBI-704760 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:apba1_rat(display_long)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Apba1(gene name)|psi-mi:Apba1(display_short)|uniprotkb:Mint1(gene name synonym)|uniprotkb:X11(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704775 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:620844|refseq:NP_113967.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR030530|mint:O35430|interpro:IPR036034|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:4DBB|rcsb pdb:6KMH|reactome:R-RNO-212676 - - - comment:rat alpha1-syntrophin and beta1-syntrophin were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:ybffWeGU/EFTeYx031rgcwPB2w410116 intact-crc:7987B02FF3CA2296|rigid:k5ewd7OUB9YH0cYstSSr2I5pFs8 false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q62915 intact:EBI-704583 intact:EBI-704635 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:cskp_rat(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704775 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:62004|refseq:NP_071520.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|rcsb pdb:1RSO|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|reactome:R-RNO-6794361|rcsb pdb:6LNM|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis) - - - comment:rat alpha1-syntrophin and beta1-syntrophin were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:S7T42QMExgUKMZpBQEJNjQeR9ZE10116 intact-crc:7987B02FF3CA2296|rigid:k5ewd7OUB9YH0cYstSSr2I5pFs8 false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q792I0 intact:EBI-704583 intact:EBI-704626|ensembl:ENSRNOP00000065941 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:lin7c_rat(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:Lin7c(gene name)|psi-mi:Lin7c(display_short)|uniprotkb:Mals3(gene name synonym)|uniprotkb:Veli3(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704775 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:621164|refseq:NP_068623.1|ensembl:ENSRNOG00000045698(gene)|ensembl:ENSRNOT00000073258(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676 - - - comment:rat alpha1-syntrophin and beta1-syntrophin were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:F2rasaJ64Olc9qScN79LJRqsUEE10116 intact-crc:7987B02FF3CA2296|rigid:k5ewd7OUB9YH0cYstSSr2I5pFs8 false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q9Z250 intact:EBI-704583 intact:EBI-704603|uniprotkb:Q9Z251 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:lin7a_rat(display_long)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Lin7a(gene name)|psi-mi:Lin7a(display_short)|uniprotkb:Mals1(gene name synonym)|uniprotkb:Veli1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704775 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:621256|refseq:NP_445966.1|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0097016"(L27 domain binding) - - - comment:rat alpha1-syntrophin and beta1-syntrophin were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:idN6PywIN4UCisrRHcL+IWuH56M10116 intact-crc:7987B02FF3CA2296|rigid:k5ewd7OUB9YH0cYstSSr2I5pFs8 false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q62696 intact:EBI-704583 intact:EBI-389325 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704775 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N - - - comment:rat alpha1-syntrophin and beta1-syntrophin were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:7987B02FF3CA2296|rigid:k5ewd7OUB9YH0cYstSSr2I5pFs8 false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q62696 intact:EBI-704583 intact:EBI-389325 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704879 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N - - - comment:rat dystrobrevin alpha2, dystrophin Dp427 and beta-syntrophin were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:161C1F475658D4E0|rigid:E69LTT2vT2Gzhz/CoSP/F8ELYYA false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q62915 intact:EBI-704583 intact:EBI-704635 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:cskp_rat(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704879 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:62004|refseq:NP_071520.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|rcsb pdb:1RSO|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|reactome:R-RNO-6794361|rcsb pdb:6LNM|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis) - - - comment:rat dystrobrevin alpha2, dystrophin Dp427 and beta-syntrophin were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:S7T42QMExgUKMZpBQEJNjQeR9ZE10116 intact-crc:161C1F475658D4E0|rigid:E69LTT2vT2Gzhz/CoSP/F8ELYYA false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q792I0 intact:EBI-704583 intact:EBI-704626|ensembl:ENSRNOP00000065941 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:lin7c_rat(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:Lin7c(gene name)|psi-mi:Lin7c(display_short)|uniprotkb:Mals3(gene name synonym)|uniprotkb:Veli3(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-704879 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:621164|refseq:NP_068623.1|ensembl:ENSRNOG00000045698(gene)|ensembl:ENSRNOT00000073258(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676 - - - comment:rat dystrobrevin alpha2, dystrophin Dp427 and beta-syntrophin were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:F2rasaJ64Olc9qScN79LJRqsUEE10116 intact-crc:161C1F475658D4E0|rigid:E69LTT2vT2Gzhz/CoSP/F8ELYYA false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P52188 uniprotkb:Q62915 intact:EBI-704583 intact:EBI-704635 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:cskp_rat(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706091 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:62004|refseq:NP_071520.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|rcsb pdb:1RSO|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|reactome:R-RNO-6794361|rcsb pdb:6LNM|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis) - - - comment:rat dystrophins dp71, alpha-dystrobrevin-2 and synthrophins proteins were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:S7T42QMExgUKMZpBQEJNjQeR9ZE10116 intact-crc:A8C3F72136AD780E|rigid:E69LTT2vT2Gzhz/CoSP/F8ELYYA false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:Q792I0 intact:EBI-704583 intact:EBI-704626|ensembl:ENSRNOP00000065941 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:lin7c_rat(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:Lin7c(gene name)|psi-mi:Lin7c(display_short)|uniprotkb:Mals3(gene name synonym)|uniprotkb:Veli3(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706091 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:621164|refseq:NP_068623.1|ensembl:ENSRNOG00000045698(gene)|ensembl:ENSRNOT00000073258(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676 - - - comment:rat dystrophins dp71, alpha-dystrobrevin-2 and synthrophins proteins were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:F2rasaJ64Olc9qScN79LJRqsUEE10116 intact-crc:A8C3F72136AD780E|rigid:E69LTT2vT2Gzhz/CoSP/F8ELYYA false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P52188 uniprotkb:Q62696 intact:EBI-704583 intact:EBI-389325 psi-mi:kcj12_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 12(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.2"(gene name synonym)|uniprotkb:Kcnj12(gene name)|psi-mi:Kcnj12(display_short)|uniprotkb:Irk2(gene name synonym) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706091 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621660|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003272(Potassium channel, inwardly rectifying, Kir2.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296053|reactome:R-RNO-5576886|reactome:R-RNO-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990573"(potassium ion import across plasma membrane) rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N - - - comment:rat dystrophins dp71, alpha-dystrobrevin-2 and synthrophins proteins were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:KS3Ch7qr0BEoAeyriaVDAQ142J410116 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:A8C3F72136AD780E|rigid:E69LTT2vT2Gzhz/CoSP/F8ELYYA false sufficient binding region:?-?|necessary binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35561 uniprotkb:Q62915 intact:EBI-703793|ensembl:ENSMUSP00000037192 intact:EBI-704635 psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym) psi-mi:cskp_rat(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272 rgd:62004|refseq:NP_071520.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|rcsb pdb:1RSO|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|reactome:R-RNO-6794361|rcsb pdb:6LNM|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis) - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090 rogid:S7T42QMExgUKMZpBQEJNjQeR9ZE10116 intact-crc:627B7738EF498964|rigid:iazYx+YQysXTBCKplpDbOXWAbmE false sufficient binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35561 uniprotkb:Q792I0 intact:EBI-703793|ensembl:ENSMUSP00000037192 intact:EBI-704626|ensembl:ENSRNOP00000065941 psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym) psi-mi:lin7c_rat(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:Lin7c(gene name)|psi-mi:Lin7c(display_short)|uniprotkb:Mals3(gene name synonym)|uniprotkb:Veli3(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272 rgd:621164|refseq:NP_068623.1|ensembl:ENSRNOG00000045698(gene)|ensembl:ENSRNOT00000073258(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090 rogid:F2rasaJ64Olc9qScN79LJRqsUEE10116 intact-crc:627B7738EF498964|rigid:iazYx+YQysXTBCKplpDbOXWAbmE false sufficient binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35561 uniprotkb:Q62696 intact:EBI-703793|ensembl:ENSMUSP00000037192 intact:EBI-389325 psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272 rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:627B7738EF498964|rigid:iazYx+YQysXTBCKplpDbOXWAbmE false sufficient binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48050 uniprotkb:Q62915 intact:EBI-706117|ensembl:ENSP00000306497|uniprotkb:Q14D44 intact:EBI-704635 psi-mi:kcnj4_human(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 4(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.3"(gene name synonym)|uniprotkb:Hippocampal inward rectifier(gene name synonym)|uniprotkb:HIRK2(gene name synonym)|uniprotkb:HRK1(gene name synonym)|uniprotkb:IRK3(gene name synonym)|uniprotkb:KCNJ4(gene name)|psi-mi:KCNJ4(display_short) psi-mi:cskp_rat(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168135(gene)|ensembl:ENST00000303592(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003273(Potassium channel, inwardly rectifying, Kir2.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|rcsb pdb:3GJ9|reactome:R-HSA-1296041|reactome:R-HSA-1296053|reactome:R-HSA-5576886|reactome:R-HSA-997272|refseq:NP_004972.1|refseq:NP_690607.1 rgd:62004|refseq:NP_071520.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|rcsb pdb:1RSO|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676|reactome:R-RNO-6794361|rcsb pdb:6LNM|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis) - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:uHnUjkbaX0skIbR8UuCQgRgzGI89606 rogid:S7T42QMExgUKMZpBQEJNjQeR9ZE10116 intact-crc:79F445A3E54CA4B9|rigid:XP+FMUz3HBUNcwRtUsXhw92GF5M false glutathione s tranferase tag:?-?|sufficient binding region:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48050 uniprotkb:Q62696 intact:EBI-706117|ensembl:ENSP00000306497|uniprotkb:Q14D44 intact:EBI-389325 psi-mi:kcnj4_human(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 4(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.3"(gene name synonym)|uniprotkb:Hippocampal inward rectifier(gene name synonym)|uniprotkb:HIRK2(gene name synonym)|uniprotkb:HRK1(gene name synonym)|uniprotkb:IRK3(gene name synonym)|uniprotkb:KCNJ4(gene name)|psi-mi:KCNJ4(display_short) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168135(gene)|ensembl:ENST00000303592(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003273(Potassium channel, inwardly rectifying, Kir2.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|rcsb pdb:3GJ9|reactome:R-HSA-1296041|reactome:R-HSA-1296053|reactome:R-HSA-5576886|reactome:R-HSA-997272|refseq:NP_004972.1|refseq:NP_690607.1 rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:uHnUjkbaX0skIbR8UuCQgRgzGI89606 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:79F445A3E54CA4B9|rigid:XP+FMUz3HBUNcwRtUsXhw92GF5M false glutathione s tranferase tag:?-?|sufficient binding region:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48050 uniprotkb:Q792I0 intact:EBI-706117|ensembl:ENSP00000306497|uniprotkb:Q14D44 intact:EBI-704626|ensembl:ENSRNOP00000065941 psi-mi:kcnj4_human(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 4(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.3"(gene name synonym)|uniprotkb:Hippocampal inward rectifier(gene name synonym)|uniprotkb:HIRK2(gene name synonym)|uniprotkb:HRK1(gene name synonym)|uniprotkb:IRK3(gene name synonym)|uniprotkb:KCNJ4(gene name)|psi-mi:KCNJ4(display_short) psi-mi:lin7c_rat(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:Lin7c(gene name)|psi-mi:Lin7c(display_short)|uniprotkb:Mals3(gene name synonym)|uniprotkb:Veli3(gene name synonym) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-706129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168135(gene)|ensembl:ENST00000303592(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003273(Potassium channel, inwardly rectifying, Kir2.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|rcsb pdb:3GJ9|reactome:R-HSA-1296041|reactome:R-HSA-1296053|reactome:R-HSA-5576886|reactome:R-HSA-997272|refseq:NP_004972.1|refseq:NP_690607.1 rgd:621164|refseq:NP_068623.1|ensembl:ENSRNOG00000045698(gene)|ensembl:ENSRNOT00000073258(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|reactome:R-RNO-212676 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2014/10/16 rogid:uHnUjkbaX0skIbR8UuCQgRgzGI89606 rogid:F2rasaJ64Olc9qScN79LJRqsUEE10116 intact-crc:79F445A3E54CA4B9|rigid:XP+FMUz3HBUNcwRtUsXhw92GF5M false glutathione s tranferase tag:?-?|sufficient binding region:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49655 uniprotkb:P11530 intact:EBI-706185|uniprotkb:Q62790 intact:EBI-706166|ensembl:ENSRNOP00000029969|uniprotkb:F1M705 psi-mi:kcj10_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 10(gene name synonym)|uniprotkb:ATP-sensitive inward rectifier potassium channel KAB-2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.1"(gene name synonym)|uniprotkb:BIR10(gene name synonym)|uniprotkb:"Brain-specific inwardly rectifying K(+) channel 1"(gene name synonym)|uniprotkb:Kcnj10(gene name)|psi-mi:Kcnj10(display_short)|uniprotkb:Kab-2(gene name synonym) psi-mi:dmd_rat(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short) psi-mi:"MI:0096"(pull down) Leonoudakis et al. (2004) pubmed:15024025 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-706172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113790.2|refseq:XP_008767959.1|rgd:61822|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003269(Potassium channel, inwardly rectifying, Kir1.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|refseq:XP_017454263.1|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296067|reactome:R-RNO-997272|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007601"(visual perception)|go:"GO:0007628"(adult walking behavior)|go:"GO:0009637"(response to blue light)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051935"(glutamate reuptake)|go:"GO:0051938"(L-glutamate import)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane) ensembl:ENSRNOG00000046366(gene)|ensembl:ENSRNOT00000035692(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|rgd:2507|refseq:XP_017457399.1|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014904"(myotube cell development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|reactome:R-RNO-390522 - - - comment:Rat dystrophin dp71, alpha-dystrobrevin-2 and synthrophins proteins were also identified|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/03 2016/01/15 rogid:ri6d3VbUvSLj12uMiqruQGL09sE10116 rogid:+tB82I1CIAu/nuaXmqNoSWqLp0o10116 intact-crc:8899C6702EF311D7|rigid:t6QoYvupi4UyXwbPn8fVgICWgNs false sufficient binding region:?-?|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)