#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-1108795	uniprotkb:P57075	-	intact:EBI-2105393|uniprotkb:Q6HA34|uniprotkb:Q6HA35|uniprotkb:Q6ISI6|uniprotkb:Q6ISK3|uniprotkb:Q6ISS9|uniprotkb:G5E9E4|ensembl:ENSP00000317327	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:ubs3a_human(display_long)|uniprotkb:UBASH3A(gene name)|psi-mi:UBASH3A(display_short)|uniprotkb:STS2(gene name synonym)|uniprotkb:Suppressor of T-cell receptor signaling 2(gene name synonym)|uniprotkb:Cbl-interacting protein 4(gene name synonym)|uniprotkb:T-cell ubiquitin ligand 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001001895.1|refseq:NP_061834.1|refseq:NP_001230396.1|ensembl:ENSG00000160185(gene)|ensembl:ENST00000319294(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR009060(UBA-like)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029033|interpro:IPR035634|interpro:IPR036028|mint:P57075|rcsb pdb:2CRN|rcsb pdb:5WDI	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:YL9PQwQzBcuWaZebBlx1WRrVJOQ9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O15524	-	intact:EBI-968198|ensembl:ENSP00000329418|ensembl:ENSP00000496577|uniprotkb:O15097|uniprotkb:Q9NSA7	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:socs1_human(display_long)|uniprotkb:SOCS1(gene name)|psi-mi:SOCS1(display_short)|uniprotkb:SSI1(gene name synonym)|uniprotkb:TIP3(gene name synonym)|uniprotkb:JAK-binding protein(gene name synonym)|uniprotkb:STAT-induced STAT inhibitor 1(gene name synonym)|uniprotkb:Tec-interacting protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010533"(regulation of activation of Janus kinase activity)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR028411|interpro:IPR035861|interpro:IPR036036|interpro:IPR036860|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|mint:O15524|reactome:R-HSA-1266695|reactome:R-HSA-1433559|reactome:R-HSA-166058|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983168|ensembl:ENSG00000185338(gene)|ensembl:ENST00000332029(transcript)|ensembl:ENST00000644787(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|refseq:NP_003736.1|dip:DIP-29662N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:Ybb6XvshFQp4GUNEiBZ41ff/H8I9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P05783	-	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q15262	-	intact:EBI-474052|uniprotkb:Q14763|uniprotkb:Q5TG10|uniprotkb:Q5TG11|uniprotkb:B2RTQ8|uniprotkb:B7ZMG0|ensembl:ENSP00000357198|ensembl:ENSP00000486442	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:ptprk_human(display_long)|uniprotkb:PTPRK(gene name)|psi-mi:PTPRK(display_short)|uniprotkb:PTPK(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001129120.1|refseq:NP_002835.2|refseq:NP_001278910.1|refseq:NP_001278913.1|ensembl:ENSG00000152894(gene)|ensembl:ENSG00000273993(gene)|ensembl:ENST00000368215(transcript)|ensembl:ENST00000628183(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031256"(leading edge membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048041"(focal adhesion assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|rcsb pdb:2C7S|reactome:R-HSA-182971|interpro:IPR000998(MAM)	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:40yQxlMyaqsPBoKB+vm75uweT9Y9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q13574	-	intact:EBI-715507|uniprotkb:B7Z6M3|uniprotkb:F6UCU9|uniprotkb:O00542|ensembl:ENSP00000395684|uniprotkb:Q6ZVG7|uniprotkb:B7Z2M9|uniprotkb:E9PPW4|uniprotkb:J3KNJ6|uniprotkb:G3V0F6|uniprotkb:Q8IVW9	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:dgkz_human(display_long)|uniprotkb:Diglyceride kinase zeta(gene name synonym)|uniprotkb:DGKZ(gene name)|psi-mi:DGKZ(display_short)|uniprotkb:DAGK6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001099010.1|refseq:NP_001186195.1|refseq:NP_001186196.1|refseq:NP_001186197.1|refseq:NP_003637.2|refseq:NP_963290.1|refseq:NP_963291.2|ensembl:ENSG00000149091(gene)|ensembl:ENST00000456247(transcript)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016301"(kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0030027"(lamellipodium)|go:"GO:0030168"(platelet activation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046486"(glycerolipid metabolic process)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090216"(positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR002110(Ankyrin)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037607|mint:Q13574|rcsb pdb:5ELQ|reactome:R-HSA-114508	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:EKgF3mjiIiVPErkqMVnYL+JHxwI9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O14654	-	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q14004	-	intact:EBI-968626|intact:EBI-28974753|ensembl:ENSP00000181839|uniprotkb:Q6DKQ9|uniprotkb:Q75MH4|uniprotkb:Q75MH5|uniprotkb:Q96JN4|uniprotkb:Q9H4A0|uniprotkb:Q9H4A1|uniprotkb:Q9UDR4|uniprotkb:Q53G78	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:cdk13_human(display_long)|uniprotkb:CDK13(gene name)|psi-mi:CDK13(display_short)|uniprotkb:CDC2L(gene name synonym)|uniprotkb:CHED(gene name synonym)|uniprotkb:KIAA1791(gene name synonym)|uniprotkb:CDC2-related protein kinase 5(gene name synonym)|uniprotkb:Cholinesterase-related cell division controller(gene name synonym)|uniprotkb:CDC2L5(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 5(gene name synonym)|uniprotkb:Cell division protein kinase 13(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019908"(nuclear cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030332"(cyclin binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5EFQ|rcsb pdb:7NXJ|reactome:R-HSA-6796648|reactome:R-HSA-6798695|go:"GO:0006468"(protein phosphorylation)|ensembl:ENSG00000065883(gene)|ensembl:ENST00000181839(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0002945"(cyclin K-CDK13 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|ensembl:ENSP00000181839|ensembl:ENST00000340829|ensembl:ENSP00000340557|refseq:NP_003709.3|refseq:NP_112557.2	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:kiNxSZsIO+CZ6ELhDpe1r2OooOs9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q7RTS7	-	intact:EBI-968660|ensembl:ENSP00000307240|uniprotkb:Q86Y45|uniprotkb:B5MD61	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:k2c74_human(display_long)|uniprotkb:Keratin-74(gene name synonym)|uniprotkb:KRT74(gene name)|psi-mi:KRT74(display_short)|uniprotkb:K6IRS4(gene name synonym)|uniprotkb:KB37(gene name synonym)|uniprotkb:KRT5C(gene name synonym)|uniprotkb:KRT6IRS4(gene name synonym)|uniprotkb:Cytokeratin-74(gene name synonym)|uniprotkb:Type-II keratin Kb37(gene name synonym)|uniprotkb:Type II inner root sheath-specific keratin-K6irs4(gene name synonym)|uniprotkb:Keratin-5c(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000170484(gene)|ensembl:ENST00000305620(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990254"(keratin filament binding)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_778223.2	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:T9fNg4NboHIB+rHX047sDa9EH9g9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q96SB8	-	intact:EBI-605415|ensembl:ENSP00000323439|ensembl:ENSP00000384539|ensembl:ENSP00000404092|uniprotkb:Q05BV4|uniprotkb:Q9H0X3|uniprotkb:Q9H6M0|intact:EBI-2557379|uniprotkb:A8K8Q6|uniprotkb:D6W518	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:smc6_human(display_long)|uniprotkb:SMC6(gene name)|psi-mi:SMC6(display_short)|uniprotkb:SMC6L1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000163029(gene)|ensembl:ENST00000351948(transcript)|ensembl:ENST00000402989(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000448223(transcript)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035061"(interchromatin granule)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0090398"(cellular senescence)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0000722"(telomere maintenance via recombination)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR027417|reactome:R-HSA-3108214|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000803"(sex chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|refseq:NP_001135758.1|refseq:NP_078900.1|refseq:XP_016860404.1|dip:DIP-34562N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:R9LrVYPHjbjxnSUVgDl8e8hqOtg9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P19174	-	intact:EBI-79387|uniprotkb:Q2V575|uniprotkb:B9EGH4|uniprotkb:B7ZLY7|uniprotkb:E1P5W4|intact:EBI-3959906|ensembl:ENSP00000362368	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:plcg1_human(display_long)|uniprotkb:PLC-148(gene name synonym)|uniprotkb:PLC1(gene name synonym)|uniprotkb:Phospholipase C-II(gene name synonym)|uniprotkb:PLCG1(gene name)|psi-mi:PLCG1(display_short)|uniprotkb:Phosphoinositide phospholipase C-gamma-1(gene name synonym)|uniprotkb:Phospholipase C-gamma-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_002651.2|refseq:NP_877963.1|dip:DIP-100N|ensembl:ENSG00000124181(gene)|ensembl:ENST00000373271(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0050429"(calcium-dependent phospholipase C activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028380|interpro:IPR035023|interpro:IPR035024|interpro:IPR035724|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|mint:P19174|rcsb pdb:1HSQ|rcsb pdb:2HSP|rcsb pdb:4EY0|rcsb pdb:4FBN|rcsb pdb:7NXE|reactome:R-HSA-1169408|reactome:R-HSA-1236382|reactome:R-HSA-1251932|reactome:R-HSA-1489509|reactome:R-HSA-167021|reactome:R-HSA-1855204|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029485|reactome:R-HSA-210990|reactome:R-HSA-212718|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-418890|reactome:R-HSA-5218921|reactome:R-HSA-5637810|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9026527|reactome:R-HSA-9027277|reactome:R-HSA-9034793|reactome:R-HSA-9664323|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:pJsNLrqg3cUj0SdjoyLf+/91yBo9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q9P0L2	-	intact:EBI-968587|uniprotkb:Q2HIY1|uniprotkb:Q5VTF9|uniprotkb:Q5VTG0|uniprotkb:Q96SW9|uniprotkb:Q9P251|uniprotkb:D3DTB0|uniprotkb:D3DTB1|ensembl:ENSP00000355884	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:mark1_human(display_long)|uniprotkb:MARK1(gene name)|psi-mi:MARK1(display_short)|uniprotkb:KIAA1477(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:MAP/microtubule affinity-regulating kinase 1(gene name synonym)|uniprotkb:PAR1 homolog c(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001273057.1|refseq:NP_061120.3|ensembl:ENSP00000355884|ensembl:ENST00000366918|ensembl:ENSP00000355885|dip:DIP-39777N|ensembl:ENSG00000116141(gene)|ensembl:ENST00000366917(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033627|mint:Q9P0L2|rcsb pdb:2HAK|rcsb pdb:3OSE|rcsb pdb:6C9D	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:/ydFAiGjuUcmwDHO4tEPSSMlVjY9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q14573	-	intact:EBI-351055|uniprotkb:Q14649|uniprotkb:Q5TAQ2|intact:EBI-28978202|ensembl:ENSP00000363435|ensembl:ENSP00000475177	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:itpr3_human(display_long)|uniprotkb:ITPR3(gene name)|psi-mi:ITPR3(display_short)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_002215.2|ensembl:ENSP00000363435|ensembl:ENSP00000475177|ensembl:ENSG00000096433(gene)|ensembl:ENST00000374316(transcript)|ensembl:ENST00000605930(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:Q14573|rcsb pdb:6DQJ|rcsb pdb:6DQN|rcsb pdb:6DQS|rcsb pdb:6DQV|rcsb pdb:6DQZ|rcsb pdb:6DR0|rcsb pdb:6DR2|rcsb pdb:6DRA|rcsb pdb:6DRC|rcsb pdb:6UQK|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|go:"GO:0007613"(memory)|reactome:R-HSA-983695	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:O+1OC4E0IrAOt+D672eXnhWHy3I9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q9Y581	-	intact:EBI-968571|ensembl:ENSP00000371054|uniprotkb:A0AVS0|uniprotkb:Q9NS16	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:insl6_human(display_long)|uniprotkb:INSL6(gene name)|psi-mi:INSL6(display_short)|uniprotkb:RIF1(gene name synonym)|uniprotkb:Relaxin/insulin-like factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000120210(gene)|ensembl:ENST00000381641(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|interpro:IPR016179(Insulin-like)|interpro:IPR017100(Insulin-like peptide 6)|interpro:IPR022353|interpro:IPR036438|refseq:NP_009110.2	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:kAAeQ0LdmaaCNja+KYlUaLEkp3Y9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q08881	-	intact:EBI-968552|intact:EBI-5773727|intact:EBI-28978067|ensembl:ENSP00000398655|uniprotkb:Q32ML7|uniprotkb:B2R752	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:itk_human(display_long)|uniprotkb:ITK(gene name)|psi-mi:ITK(display_short)|uniprotkb:EMT(gene name synonym)|uniprotkb:LYK(gene name synonym)|uniprotkb:T-cell-specific kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase Lyk(gene name synonym)|uniprotkb:Kinase EMT(gene name synonym)|uniprotkb:Interleukin-2-inducible T-cell kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000113263(gene)|ensembl:ENST00000422843(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042110"(T cell activation)|go:"GO:0046629"(gamma-delta T cell activation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR001562(Tec/Btk)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035583|interpro:IPR036028|interpro:IPR036860|interpro:IPR042785|mint:Q08881|rcsb pdb:1SM2|rcsb pdb:1SNU|rcsb pdb:1SNX|rcsb pdb:2E6I|rcsb pdb:2LMJ|rcsb pdb:2YUQ|rcsb pdb:3MIY|rcsb pdb:3MJ1|rcsb pdb:3MJ2|rcsb pdb:3QGW|rcsb pdb:3QGY|rcsb pdb:3T9T|interpro:IPR001849(Pleckstrin-like)|rcsb pdb:3V5J|rcsb pdb:3V5L|rcsb pdb:3V8T|rcsb pdb:3V8W|rcsb pdb:4HCT|rcsb pdb:4HCU|rcsb pdb:4HCV|rcsb pdb:4KIO|rcsb pdb:4L7S|rcsb pdb:4M0Y|rcsb pdb:4M0Z|rcsb pdb:4M12|rcsb pdb:4M13|rcsb pdb:4M14|rcsb pdb:4M15|rcsb pdb:4MF0|rcsb pdb:4MF1|rcsb pdb:4PP9|rcsb pdb:4PPA|rcsb pdb:4PPB|rcsb pdb:4PPC|rcsb pdb:4PQN|rcsb pdb:4QD6|rcsb pdb:4RFM|reactome:R-HSA-202433|reactome:R-HSA-2871809|refseq:NP_005537.3|ensembl:ENSP00000398655|dip:DIP-29974N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:DbmEoJ3gxf6xJrG1Qn4mAXASfw89606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q13233	-	intact:EBI-49776|ensembl:ENSP00000382423	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:m3k1_human(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:MAP3K1(gene name)|psi-mi:MAP3K1(display_short)|uniprotkb:MAPKKK1(gene name synonym)|uniprotkb:MEKK(gene name synonym)|uniprotkb:MEKK1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_005912.1|ensembl:ENSP00000382423|dip:DIP-27520N|ensembl:ENSG00000095015(gene)|ensembl:ENST00000399503(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13233|rcsb pdb:6WHB|reactome:R-HSA-166058|reactome:R-HSA-2871796|reactome:R-HSA-933542|reactome:R-HSA-975138|reactome:R-HSA-975871	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:kxdotY9M7Rd4Xr4IIlf7NVv7AC89606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q15746	-	intact:EBI-968482|intact:EBI-28987351|ensembl:ENSP00000353452|uniprotkb:O95796|uniprotkb:O95797|uniprotkb:O95798|uniprotkb:O95799|uniprotkb:Q14844|uniprotkb:Q16794|uniprotkb:Q5MY99|uniprotkb:Q5MYA0|intact:EBI-1758586|uniprotkb:B4DUE3|uniprotkb:D3DN97|uniprotkb:Q17S15|uniprotkb:Q6P2N0|uniprotkb:Q7Z4J0|uniprotkb:Q9C0L5|uniprotkb:Q9UBG5|uniprotkb:Q9UIT9|intact:EBI-1963605|uniprotkb:Q3ZCP9|uniprotkb:Q9UBY6	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:mylk_human(display_long)|uniprotkb:MYLK(gene name)|psi-mi:MYLK(display_short)|uniprotkb:MLCK(gene name synonym)|uniprotkb:Telokin(gene name synonym)|uniprotkb:Kinase-related protein(gene name synonym)|uniprotkb:MLCK1(gene name synonym)|uniprotkb:MYLK1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000065534(gene)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0014820"(tonic smooth muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046872"(metal ion binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015725(Myosin Light Chain Kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036116|ensembl:ENST00000360304(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004687"(myosin light chain kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|interpro:IPR036179|rcsb pdb:2K0F|rcsb pdb:2YR3|rcsb pdb:2CQV|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:6C6M|reactome:R-HSA-445355|reactome:R-HSA-5627123|refseq:NP_444253.3|refseq:NP_444254.3|refseq:NP_444255.3|refseq:NP_444256.3|refseq:NP_444259.1|refseq:NP_001308238.1|refseq:XP_011511162.1|ensembl:ENST00000346322|ensembl:ENSP00000320622|ensembl:ENSP00000354004|ensembl:ENST00000418370|ensembl:ENSP00000428967|ensembl:ENST00000578202|ensembl:ENSP00000463691|ensembl:ENST00000583087|ensembl:ENSP00000462118|ensembl:ENST00000360772|ensembl:ENSP00000353452|refseq:NP_444260.1|refseq:XP_016861958.1|refseq:XP_016861960.1|refseq:XP_016861961.1|refseq:XP_016861962.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:Wm0QbKY5KOVPytbFu5NCcT0Z1ek9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P21709	-	intact:EBI-968453|ensembl:ENSP00000275815|ensembl:ENSP00000494931|uniprotkb:B5A966|uniprotkb:B5A967|uniprotkb:Q15405|uniprotkb:A1L3V3	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:epha1_human(display_long)|uniprotkb:EPHA1(gene name)|psi-mi:EPHA1(display_short)|uniprotkb:EPH(gene name synonym)|uniprotkb:EPHT(gene name synonym)|uniprotkb:EPHT1(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH(gene name synonym)|uniprotkb:EPH tyrosine kinase(gene name synonym)|uniprotkb:EPH tyrosine kinase 1(gene name synonym)|uniprotkb:Erythropoietin-producing hepatoma receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000146904(gene)|ensembl:ENSG00000284816(gene)|ensembl:ENST00000275815(transcript)|ensembl:ENST00000645847(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034251|interpro:IPR036116|mint:P21709|rcsb pdb:2K1K|rcsb pdb:2K1L|rcsb pdb:3HIL|rcsb pdb:3KKA|reactome:R-HSA-2682334|reactome:R-HSA-2892247|reactome:R-HSA-3928663|reactome:R-HSA-3928665|refseq:NP_005223.4|dip:DIP-34886N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:TB6kRxNntZnW6eicjTb94922jDM9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P46199	-	intact:EBI-359432|ensembl:ENSP00000263629|ensembl:ENSP00000378099|ensembl:ENSP00000384481|uniprotkb:D6W5D0	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:if2m_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001307933.1|refseq:NP_001307934.1|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0070124"(mitochondrial translational initiation)|interpro:IPR000178(Initiation factor 2)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR036925|interpro:IPR044145|rcsb pdb:6GAW|rcsb pdb:6GAZ|rcsb pdb:6GB2|rcsb pdb:6RW5|reactome:R-HSA-5368286|ensembl:ENSG00000085760(gene)|ensembl:ENST00000263629(transcript)|ensembl:ENST00000394600(transcript)|ensembl:ENST00000403721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0032790"(ribosome disassembly)|refseq:NP_001005369.1|refseq:NP_002444.2|refseq:XP_011531173.1|refseq:NP_001307930.1|refseq:NP_001307931.1|refseq:NP_001307932.1|refseq:XP_005264392.1|refseq:XP_016859651.1|refseq:XP_016859652.1|dip:DIP-27596N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:ThigwWzs0gInoPjmmd8DYvyrWw49606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P52333	-	intact:EBI-518246|uniprotkb:Q13259|uniprotkb:Q13260|uniprotkb:Q13611|uniprotkb:Q9Y6S2|uniprotkb:Q99699|uniprotkb:Q8N1E8|ensembl:ENSP00000391676|ensembl:ENSP00000432511	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:jak3_human(display_long)|uniprotkb:Janus kinase 3(gene name synonym)|uniprotkb:Leukocyte janus kinase(gene name synonym)|uniprotkb:JAK3(gene name)|psi-mi:JAK3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_000206.2|dip:DIP-274N|ensembl:ENST00000458235(transcript)|ensembl:ENST00000527670(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002731"(negative regulation of dendritic cell cytokine production)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007167"(enzyme linked receptor protein signaling pathway)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070669"(response to interleukin-2)|go:"GO:0070670"(response to interleukin-4)|go:"GO:0070672"(response to interleukin-15)|go:"GO:0071104"(response to interleukin-9)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR020775|interpro:IPR036860|interpro:IPR041046|rcsb pdb:4HVI|rcsb pdb:4I6Q|rcsb pdb:4QPS|rcsb pdb:4QT1|rcsb pdb:4RIO|rcsb pdb:4V0G|rcsb pdb:4Z16|interpro:IPR041155|interpro:IPR041381|rcsb pdb:1YVJ|rcsb pdb:5LWM|rcsb pdb:5LWN|rcsb pdb:3LXK|rcsb pdb:3LXL|rcsb pdb:3PJC|rcsb pdb:3ZC6|rcsb pdb:3ZEP|rcsb pdb:4HVD|rcsb pdb:4HVG|rcsb pdb:4HVH|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0045087"(innate immune response)|go:"GO:0045221"(negative regulation of FasL production)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|ensembl:ENSG00000105639(gene)|reactome:R-HSA-9020958|reactome:R-HSA-912526|reactome:R-HSA-9679191|rcsb pdb:5TOZ|rcsb pdb:5TTS|rcsb pdb:5TTU|rcsb pdb:5TTV|rcsb pdb:5VO6|rcsb pdb:5W86|rcsb pdb:5WFJ|rcsb pdb:6AAK|rcsb pdb:6DA4|rcsb pdb:6DB3|rcsb pdb:6DB4|rcsb pdb:6DUD|rcsb pdb:6GL9|rcsb pdb:6GLA|rcsb pdb:6GLB|rcsb pdb:6HZV|rcsb pdb:6NY4|rcsb pdb:7APF|rcsb pdb:7APG|rcsb pdb:7C3N|reactome:R-HSA-1266695|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8985947|reactome:R-HSA-9020558	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:cHXRp+Xei7sembAUQyV46ooa+P49606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P40763	-	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	crc64:6C00632211C8012D	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q9H479	-	intact:EBI-968410|ensembl:ENSP00000300784	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:fn3k_human(display_long)|uniprotkb:FN3K(gene name)|psi-mi:FN3K(display_short)|uniprotkb:Protein-psicosamine 3-kinase FN3K(gene name synonym)|uniprotkb:Protein-ribulosamine 3-kinase FN3K(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000167363(gene)|ensembl:ENST00000300784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0030389"(fructosamine metabolic process)|go:"GO:0030393"(fructoselysine metabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036525"(protein deglycation)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0102193"(protein-ribulosamine 3-kinase activity)|go:"GO:0102194"(protein-fructosamine 3-kinase activity)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016477(Ketosamine-3-kinase)|reactome:R-HSA-163841|refseq:NP_071441.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:mRMfQGYb7f1tdgUDHp64Lyy04DI9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q00722	-	intact:EBI-968381|ensembl:ENSP00000260402|uniprotkb:A8K6J2|uniprotkb:B9EGH5	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:plcb2_human(display_long)|uniprotkb:PLCB2(gene name)|psi-mi:PLCB2(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-2(gene name synonym)|uniprotkb:Phospholipase C-beta-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001271226.1|ensembl:ENSG00000137841(gene)|ensembl:ENST00000260402(transcript)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050913"(sensory perception of bitter taste)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR028403|interpro:IPR035892|interpro:IPR037862|rcsb pdb:2FJU|rcsb pdb:2ZKM|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|go:"GO:0007202"(activation of phospholipase C activity)|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_004564.2|refseq:NP_001271227.1|dip:DIP-29259N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:Ef8OWTNQ9Mbw1r4NKGu6t29rTi09606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P52945	-	intact:EBI-968396|ensembl:ENSP00000370421|uniprotkb:O60594|uniprotkb:Q5VYW2	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:pdx1_human(display_long)|uniprotkb:PDX1(gene name)|psi-mi:PDX1(display_short)|uniprotkb:IPF1(gene name synonym)|uniprotkb:Insulin promoter factor 1(gene name synonym)|uniprotkb:Islet/duodenum homeobox-1(gene name synonym)|uniprotkb:Somatostatin-transactivating factor 1(gene name synonym)|uniprotkb:Insulin upstream factor 1(gene name synonym)|uniprotkb:Glucose-sensitive factor(gene name synonym)|uniprotkb:STF1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000139515(gene)|ensembl:ENST00000381033(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0035094"(response to nicotine)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0043201"(response to leucine)|go:"GO:0043279"(response to alkaloid)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010157"(response to chlorate)|go:"GO:0010260"(animal organ senescence)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0016607"(nuclear speck)|go:"GO:0051594"(detection of glucose)|go:"GO:0060290"(transdifferentiation)|go:"GO:0070542"(response to fatty acid)|go:"GO:0030073"(insulin secretion)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033273"(response to vitamin)|go:"GO:0034097"(response to cytokine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|rcsb pdb:6F8F|reactome:R-HSA-210745|reactome:R-HSA-210747|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|refseq:NP_000200.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:C770/atKjY7M4Yy3Q/cOHVfhySo9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O60674	-	intact:EBI-518647|uniprotkb:O14636|uniprotkb:O75297|intact:EBI-28977715|ensembl:ENSP00000371067	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:jak2_human(display_long)|uniprotkb:Janus kinase 2(gene name synonym)|uniprotkb:JAK2(gene name)|psi-mi:JAK2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001309133.1|ensembl:ENSG00000096968(gene)|ensembl:ENST00000381652(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000791"(euchromatin)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005143"(interleukin-12 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSP00000371067|refseq:NP_004963.1|refseq:NP_001309123.1|refseq:NP_001309124.1|refseq:NP_001309125.1|dip:DIP-33880N|go:"GO:0005730"(nucleolus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007167"(enzyme linked receptor protein signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031904"(endosome lumen)|go:"GO:0031959"(mineralocorticoid receptor signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035401"("histone kinase activity (H3-Y41 specific)")|go:"GO:0035409"(histone H3-Y41 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070671"(response to interleukin-12)|go:"GO:0070757"(interleukin-35-mediated signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901731"(positive regulation of platelet aggregation)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR020693|interpro:IPR035588|interpro:IPR035589|interpro:IPR035860|interpro:IPR035963|interpro:IPR036860|interpro:IPR037838|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:O60674|rcsb pdb:2B7A|rcsb pdb:2W1I|rcsb pdb:2XA4|rcsb pdb:3E62|rcsb pdb:3E63|rcsb pdb:3E64|rcsb pdb:3FUP|rcsb pdb:3IO7|rcsb pdb:3IOK|rcsb pdb:3JY9|rcsb pdb:3KCK|rcsb pdb:3KRR|rcsb pdb:3LPB|rcsb pdb:3Q32|rcsb pdb:3RVG|rcsb pdb:3TJC|rcsb pdb:3TJD|rcsb pdb:3UGC|rcsb pdb:3ZMM|rcsb pdb:4AQC|rcsb pdb:4BBE|rcsb pdb:4BBF|rcsb pdb:4C61|rcsb pdb:4C62|rcsb pdb:4D0W|rcsb pdb:4D0X|rcsb pdb:4D1S|rcsb pdb:4E4M|rcsb pdb:4E6D|rcsb pdb:4E6Q|rcsb pdb:4F08|rcsb pdb:4F09|rcsb pdb:4FVP|rcsb pdb:4FVQ|rcsb pdb:4FVR|rcsb pdb:4GFM|rcsb pdb:4GMY|rcsb pdb:4HGE|rcsb pdb:4IVA|rcsb pdb:4JI9|rcsb pdb:4JIA|rcsb pdb:4P7E|rcsb pdb:4YTC|rcsb pdb:4YTF|rcsb pdb:4YTH|rcsb pdb:4YTI|rcsb pdb:4Z32|rcsb pdb:4ZIM|rcsb pdb:5CF4|rcsb pdb:5CF5|rcsb pdb:5CF6|rcsb pdb:5CF8|rcsb pdb:5HEZ|rcsb pdb:5I4N|rcsb pdb:5L3A|rcsb pdb:5TQ3|rcsb pdb:5TQ4|rcsb pdb:5TQ5|rcsb pdb:5TQ6|rcsb pdb:5TQ7|rcsb pdb:5TQ8|rcsb pdb:5USY|rcsb pdb:5USZ|rcsb pdb:5UT0|rcsb pdb:5UT1|rcsb pdb:5UT2|rcsb pdb:5UT3|rcsb pdb:5UT4|rcsb pdb:5UT5|rcsb pdb:5UT6|rcsb pdb:5WEV|rcsb pdb:5WIJ|rcsb pdb:5WIK|rcsb pdb:5WIL|rcsb pdb:5WIM|rcsb pdb:5WIN|rcsb pdb:6AAJ|rcsb pdb:6BBV|rcsb pdb:6BRW|rcsb pdb:6BS0|rcsb pdb:6BSS|rcsb pdb:6D2I|rcsb pdb:6DRW|rcsb pdb:6E2P|rcsb pdb:6E2Q|rcsb pdb:6G3C|rcsb pdb:6M9H|rcsb pdb:6OAV|rcsb pdb:6OBB|rcsb pdb:6OBF|rcsb pdb:6OBL|rcsb pdb:6OCC|rcsb pdb:6TPD|rcsb pdb:6VGL|rcsb pdb:6VN8|rcsb pdb:6VNB|rcsb pdb:6VNC|rcsb pdb:6VNE|rcsb pdb:6VNF|rcsb pdb:6VNG|rcsb pdb:6VNH|rcsb pdb:6VNI|rcsb pdb:6VNJ|rcsb pdb:6VNK|rcsb pdb:6VNL|rcsb pdb:6VNM|rcsb pdb:6VS3|rcsb pdb:6VSN|rcsb pdb:6WTN|rcsb pdb:6WTO|rcsb pdb:6WTP|rcsb pdb:6WTQ|rcsb pdb:6X8E|rcsb pdb:6XJK|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1170546|reactome:R-HSA-1433557|reactome:R-HSA-2586552|reactome:R-HSA-3214858|reactome:R-HSA-512988|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-6802946|rcsb pdb:5AEP|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-69231|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9006335|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|reactome:R-HSA-912526|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9670439|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983231	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:s2LnvkFxriuFzkRSlP9PI0h/wYk9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P38811	-	intact:EBI-24638|uniprotkb:D3DL49|ensemblfungi:YHR099W	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:tra1_yeast(display_long)|uniprotkb:TRA1(gene name)|psi-mi:TRA1(display_short)|uniprotkb:p400 kDa component of SAGA(gene name synonym)|uniprotkb:YHR099W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_011967.1|sgd:S000001141|dip:DIP-805N|mint:P38811|ensemblfungi:YHR099W(gene)|ensemblfungi:YHR099W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016301"(kinase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070209"(ASTRA complex)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|interpro:IPR036940|rcsb pdb:5OJS|rcsb pdb:6IG9|rcsb pdb:6T9I|rcsb pdb:6T9J	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	crc64:AE3588676F5D5777	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:B/rkvJoIvK1Xi2SoNtFnFOdcp2c559292	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P49454	-	intact:EBI-968343|ensembl:ENSP00000355922|uniprotkb:Q13171|uniprotkb:Q13246|uniprotkb:Q5VVM7|intact:EBI-2563723|intact:EBI-21028103	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:cenpf_human(display_long)|uniprotkb:CENPF(gene name)|psi-mi:CENPF(display_short)|uniprotkb:Kinetochore protein CENPF(gene name synonym)|uniprotkb:Mitosin(gene name synonym)|uniprotkb:AH antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000117724(gene)|ensembl:ENST00000366955(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0001822"(kidney development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0042493"|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR018302|interpro:IPR018463|interpro:IPR019513|interpro:IPR043513|mint:P49454|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-156711|refseq:NP_057427.3|refseq:XP_016855575.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:gPlJiOCF1/MAVT80oKwlQlLgluo9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O14976	-	intact:EBI-714707|uniprotkb:Q9BVY6|uniprotkb:Q5U4P5|intact:EBI-28970318|ensembl:ENSP00000314499	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:gak_human(display_long)|uniprotkb:GAK(gene name)|psi-mi:GAK(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSP00000314499|ensembl:ENST00000511163|ensembl:ENSP00000421361|refseq:NP_005246.2|refseq:NP_001305063.1|ensembl:ENSG00000178950(gene)|ensembl:ENST00000314167(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0030276"(clathrin binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031982"(vesicle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905224"(clathrin-coated pit assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR035892|interpro:IPR036869|rcsb pdb:4C57|rcsb pdb:4C58|rcsb pdb:4C59|rcsb pdb:4O38|rcsb pdb:4Y8D|rcsb pdb:5Y7Z|rcsb pdb:5Y80|reactome:R-HSA-432722|reactome:R-HSA-8856828|go:"GO:0072318"(clathrin coat disassembly)	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:+CTVzAL9y1B3+JIg6PHsj8QXIjE9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q99683	-	intact:EBI-476263|uniprotkb:Q5THN3|uniprotkb:Q99461|uniprotkb:A6NIA0|uniprotkb:B4DGB2|ensembl:ENSP00000351908	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:m3k5_human(display_long)|uniprotkb:MAPK/ERK kinase kinase 5(gene name synonym)|uniprotkb:Apoptosis signal-regulating kinase 1(gene name synonym)|uniprotkb:MAP3K5(gene name)|psi-mi:MAP3K5(display_short)|uniprotkb:ASK1(gene name synonym)|uniprotkb:MAPKKK5(gene name synonym)|uniprotkb:MEKK5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_005914.1|dip:DIP-29516N|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|ensembl:ENSG00000197442(gene)|ensembl:ENST00000359015(transcript)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072577"(endothelial cell apoptotic process)|go:"GO:0090398"(cellular senescence)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902911"(protein kinase complex)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990604"(IRE1-TRAF2-ASK1 complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR025136|interpro:IPR043969|mint:Q99683|rcsb pdb:2CLQ|rcsb pdb:3VW6|rcsb pdb:4BF2|rcsb pdb:4BHN|rcsb pdb:4BIB|rcsb pdb:4BIC|rcsb pdb:4BID|rcsb pdb:4BIE|rcsb pdb:5ULM|rcsb pdb:5UOR|rcsb pdb:5UOX|rcsb pdb:5UP3|rcsb pdb:5V19|rcsb pdb:5V24|rcsb pdb:5VIL|rcsb pdb:5VIO|rcsb pdb:6E2M|rcsb pdb:6E2N|rcsb pdb:6E2O|rcsb pdb:6EJL|rcsb pdb:6OYT|rcsb pdb:6OYW|rcsb pdb:6VRE|rcsb pdb:6XIH|reactome:R-HSA-2559580	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:/txMHg7GSCpK8ij48YDHGARX3es9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q9BRR9	-	intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3)	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q16820	-	intact:EBI-968418|ensembl:ENSP00000269202|uniprotkb:Q670J1|uniprotkb:B7ZM35|uniprotkb:B9EGL6	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:mep1b_human(display_long)|uniprotkb:MEP1B(gene name)|psi-mi:MEP1B(display_short)|uniprotkb:Endopeptidase-2(gene name synonym)|uniprotkb:N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta(gene name synonym)|uniprotkb:PABA peptide hydrolase(gene name synonym)|uniprotkb:PPH beta(gene name synonym)|uniprotkb:Meprin B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000141434(gene)|ensembl:ENST00000269202(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017090"(meprin A complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1901998"(toxin transport)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000998(MAM)|interpro:IPR001506(Peptidase M12A, astacin)|interpro:IPR002083(MATH)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR008294(Peptidase M12A, meprin alpha subunit)|interpro:IPR008974(TRAF-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024079|interpro:IPR034038|interpro:IPR034302|rcsb pdb:4GWM|rcsb pdb:4GWN|rcsb pdb:7AQ1|rcsb pdb:7AUW|refseq:NP_005916.2|refseq:NP_001295100.1|dip:DIP-34900N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:nDkbvnrqRM45H231bQ8XUntenNM9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O14733	-	intact:EBI-492605|uniprotkb:O14648|uniprotkb:O14816|uniprotkb:O60452|uniprotkb:O60453|uniprotkb:Q1PG43|uniprotkb:Q8IY10|uniprotkb:B2R9S5|uniprotkb:D6W659|ensembl:ENSP00000381066	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:mp2k7_human(display_long)|uniprotkb:MAPK/ERK kinase 7(gene name synonym)|uniprotkb:JNK-activating kinase 2(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 2(gene name synonym)|uniprotkb:MAP2K7(gene name)|psi-mi:MAP2K7(display_short)|uniprotkb:JNKK2(gene name synonym)|uniprotkb:MKK7(gene name synonym)|uniprotkb:PRKMK7(gene name synonym)|uniprotkb:MEK7(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 4(gene name synonym)|uniprotkb:SKK4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_660186.1|ensembl:ENSG00000076984(gene)|ensembl:ENST00000397979(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0009411"(response to UV)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:O14733|rcsb pdb:2DYL|rcsb pdb:3WZU|rcsb pdb:4UX9|rcsb pdb:5B2K|rcsb pdb:5B2L|rcsb pdb:5B2M|rcsb pdb:5Y8U|rcsb pdb:5Y90|rcsb pdb:5Z1D|rcsb pdb:5Z1E|rcsb pdb:6IB0|rcsb pdb:6IB2|go:"GO:0000187"(obsolete activation of MAPK activity)|rcsb pdb:6QFL|rcsb pdb:6QFR|rcsb pdb:6QFT|rcsb pdb:6QG4|rcsb pdb:6QG7|rcsb pdb:6QHO|rcsb pdb:6QHR|rcsb pdb:6YFZ|rcsb pdb:6YG0|rcsb pdb:6YG1|rcsb pdb:6YG2|rcsb pdb:6YG3|rcsb pdb:6YG4|rcsb pdb:6YG5|rcsb pdb:6YG6|rcsb pdb:6YG7|rcsb pdb:6YZ4|rcsb pdb:7CBX|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-5210891|reactome:R-HSA-450321|refseq:NP_001284484.1|refseq:NP_001284485.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:fEJqQ+bmZXzL9rSHk/Z01SQJFKM9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q16537	-	intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P54753	-	intact:EBI-968308|ensembl:ENSP00000332118|uniprotkb:Q7Z740	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:ephb3_human(display_long)|uniprotkb:EPHB3(gene name)|psi-mi:EPHB3(display_short)|uniprotkb:ETK2(gene name synonym)|uniprotkb:HEK2(gene name synonym)|uniprotkb:EPH-like tyrosine kinase 2(gene name synonym)|uniprotkb:Tyrosine-protein kinase TYRO6(gene name synonym)|uniprotkb:TYRO6(gene name synonym)|uniprotkb:Embryonic kinase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034245|interpro:IPR036116|rcsb pdb:3P1I|rcsb pdb:3ZFY|rcsb pdb:5L6O|rcsb pdb:5L6P|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|ensembl:ENSG00000182580(gene)|ensembl:ENST00000330394(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001655"(urogenital system development)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0016477"(cell migration)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0005003"(ephrin receptor activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011641(GCC2 and GCC3)|refseq:NP_004434.2	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:oRkqmq4Kvbf5UvrNDLX+djq+E/I9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q99963	-	intact:EBI-473910|uniprotkb:O43553|uniprotkb:O43554|ensembl:ENSP00000391372	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:sh3g3_human(display_long)|uniprotkb:Endophilin-3(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 3(gene name synonym)|uniprotkb:SH3 domain protein 2C(gene name synonym)|uniprotkb:EEN-B2(gene name synonym)|uniprotkb:SH3GL3(gene name)|psi-mi:SH3GL3(display_short)|uniprotkb:CNSA3(gene name synonym)|uniprotkb:SH3D2C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001288037.1|refseq:NP_001288038.1|ensembl:ENSG00000140600(gene)|ensembl:ENST00000427482(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0006897"(endocytosis)|rcsb pdb:2Z0V|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9031628|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0098793"(presynapse)|go:"GO:0098845"(postsynaptic endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0031901"(early endosome membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR032469|interpro:IPR035824|interpro:IPR036028|mint:Q99963|rcsb pdb:2EW3|refseq:NP_003018.3|refseq:XP_011520191.1|refseq:NP_001311112.1|refseq:NP_001311114.1|refseq:NP_001311116.1|refseq:XP_016877975.1|dip:DIP-34766N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:0MBJt+lIGr7wul+tAItvkg4LqIQ9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q96HC4	-	intact:EBI-751267|uniprotkb:Q8WVK0|uniprotkb:O60705|uniprotkb:A8K6F9|uniprotkb:Q5UW38|uniprotkb:D6RB78|uniprotkb:E9PBF5|uniprotkb:Q56VN4|ensembl:ENSP00000321746	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:pdli5_human(display_long)|uniprotkb:Enigma homolog(gene name synonym)|uniprotkb:Enigma-like PDZ and LIM domains protein(gene name synonym)|uniprotkb:PDLIM5(gene name)|psi-mi:PDLIM5(display_short)|uniprotkb:L9(orf name)|uniprotkb:ENH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001011515.1|refseq:NP_001011516.1|refseq:NP_006448.4|refseq:NP_001243358.1|mint:Q96HC4|rcsb pdb:2DAR|rcsb pdb:2UZC|reactome:R-HSA-6794361|interpro:IPR036034|ensembl:ENSG00000163110(gene)|ensembl:ENST00000317968(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0042805"(actinin binding)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061061"(muscle structure development)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|go:"GO:0005829"(cytosol)|dip:DIP-34898N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:Ngp310yfoOv8KaxchoUc39mj5HE9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P20700	-	intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O75943	-	intact:EBI-968231|ensembl:ENSP00000484854|ensembl:ENSP00000370151|ensembl:ENSP00000426191|ensembl:ENSP00000477962|ensembl:ENSP00000477996|ensembl:ENSP00000478167|ensembl:ENSP00000479160|ensembl:ENSP00000482371|uniprotkb:O75714|uniprotkb:Q7Z3S4|uniprotkb:Q9UNK7|uniprotkb:Q9UNR7|uniprotkb:Q9UNR8|uniprotkb:Q9UPF5|uniprotkb:A8K8X2|uniprotkb:D3DWA5	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:rad17_human(display_long)|uniprotkb:R24L(gene name synonym)|uniprotkb:RAD17(gene name)|psi-mi:RAD17(display_short)|uniprotkb:RF-C/activator 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENST00000380774(transcript)|ensembl:ENST00000509734(transcript)|ensembl:ENST00000610770(transcript)|ensembl:ENST00000611523(transcript)|ensembl:ENST00000612044(transcript)|ensembl:ENST00000616488(transcript)|ensembl:ENST00000616759(transcript)|ensembl:ENST00000620889(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003682"(chromatin binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042325"(regulation of phosphorylation)|ensembl:ENSG00000152942(gene)|ensembl:ENSG00000276618(gene)|reactome:R-HSA-69473|interpro:IPR004582(Checkpoint protein Rad24)|interpro:IPR018324|interpro:IPR027417|mint:O75943|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|refseq:NP_001265551.1|refseq:NP_002864.1|refseq:NP_579916.1|refseq:NP_579917.1|refseq:NP_579918.1|refseq:NP_579919.1|refseq:NP_579920.1|refseq:NP_579921.1|refseq:NP_579922.1|refseq:XP_016865168.1|refseq:XP_016865169.1|refseq:XP_016865170.1|dip:DIP-24254N|dip:DIP-34896N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:VFPeq06ilaDd09F/gQm6Dtvny2A9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q9UPT6	-	intact:EBI-717887|uniprotkb:A2A2B3|uniprotkb:Q96RY4|uniprotkb:Q9H4I4|uniprotkb:Q9H7P1|uniprotkb:Q9NUG0|uniprotkb:A7E2B3|ensembl:ENSP00000250894	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:jip3_human(display_long)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:JIP3(gene name synonym)|uniprotkb:KIAA1066(gene name synonym)|uniprotkb:MAPK8IP3(gene name)|psi-mi:MAPK8IP3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001035529.1|refseq:NP_055948.2|refseq:NP_001305781.1|ensembl:ENSG00000138834(gene)|ensembl:ENST00000250894(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031103"(axon regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0044297"(cell body)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061564"(axon development)|go:"GO:0099641"(anterograde axonal protein transport)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:Q9UPT6|rcsb pdb:4PXJ|go:"GO:1904115"(axon cytoplasm)	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:PIL9w/kseAImo5TJWUxoTzlUjMg9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q92985	-	intact:EBI-968267|intact:EBI-28973647|ensembl:ENSP00000434009|ensembl:ENSP00000480358|uniprotkb:O00331|uniprotkb:O00332|uniprotkb:O00333|uniprotkb:O75924|uniprotkb:Q9UE79|intact:EBI-2339383|uniprotkb:B9EGL3	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:irf7_human(display_long)|uniprotkb:IRF7(gene name)|psi-mi:IRF7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000185507(gene)|ensembl:ENSG00000276561(gene)|ensembl:ENST00000525445(transcript)|ensembl:ENST00000621391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-HSA-3134963|go:"GO:0006974"(cellular response to DNA damage stimulus)|reactome:R-HSA-877300|reactome:R-HSA-9013973|go:"GO:0009615"(response to virus)|go:"GO:0010008"(endosome membrane)|reactome:R-HSA-909733|go:"GO:0016064"(immunoglobulin mediated immune response)|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0019043"(establishment of viral latency)|reactome:R-HSA-936964|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|reactome:R-HSA-975110|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034124"(regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0034127"(regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q92985|rcsb pdb:2O61|ensembl:ENST00000330243|ensembl:ENSP00000329411|ensembl:ENSP00000331803|ensembl:ENST00000397566|ensembl:ENSP00000380697|ensembl:ENST00000469048|ensembl:ENSP00000434607|ensembl:ENSP00000434009|ensembl:ENST00000533182|ensembl:ENSP00000433903|ensembl:ENST00000612534|ensembl:ENSP00000479615|ensembl:ENSP00000480358|ensembl:ENST00000632827|ensembl:ENSP00000488039|ensembl:ENST00000633274|ensembl:ENSP00000488591|ensembl:ENST00000633943|ensembl:ENSP00000488666|ensembl:ENST00000634105|ensembl:ENSP00000488581|ensembl:ENST00000348655|refseq:NP_001563.2|refseq:NP_004020.1|refseq:NP_004022.2|refseq:XP_005252963.1|refseq:XP_016873163.1|dip:DIP-34895N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:Wjak+z4pcHAXB3W9k+eqP4V8SuI9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O00459	-	intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P06748	-	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P23588	-	intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O75159	-	intact:EBI-970130|ensembl:ENSP00000305133|ensembl:ENSP00000378330|uniprotkb:Q8IYZ4|uniprotkb:Q53SD4	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:socs5_human(display_long)|uniprotkb:SOCS5(gene name)|psi-mi:SOCS5(display_short)|uniprotkb:CIS6(gene name synonym)|uniprotkb:CISH5(gene name synonym)|uniprotkb:CISH6(gene name synonym)|uniprotkb:KIAA0671(gene name synonym)|uniprotkb:Cytokine-inducible SH2-containing protein 5(gene name synonym)|uniprotkb:Cytokine-inducible SH2 protein 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0097699"(vascular endothelial cell response to fluid shear stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR022252|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR028420|interpro:IPR036036|interpro:IPR036860|interpro:IPR037343|mint:O75159|reactome:R-HSA-6785807|reactome:R-HSA-8951664|ensembl:ENSG00000171150(gene)|ensembl:ENST00000306503(transcript)|ensembl:ENST00000394861(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|refseq:NP_054730.1|refseq:NP_659198.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:U2knqF85DLJAaAivguVFoun87u89606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q9UM73	-	intact:EBI-357361|ensembl:ENSP00000373700|uniprotkb:Q4ZFX9|uniprotkb:Q53QQ6|uniprotkb:Q53RZ4|uniprotkb:Q59FI3|uniprotkb:Q9Y4K6	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:alk_human(display_long)|uniprotkb:ALK(gene name)|psi-mi:ALK(display_short)|uniprotkb:Anaplastic lymphoma kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000171094(gene)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0016310"(phosphorylation)|go:"GO:0021766"(hippocampus development)|go:"GO:0030534"(adult behavior)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0036269"(swimming behavior)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045664"(regulation of neuron differentiation)|ensembl:ENST00000389048(transcript)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048666"(neuron development)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090648"(response to environmental enrichment)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000998(MAM)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR026830|interpro:IPR036055|mint:Q9UM73|rcsb pdb:2KUP|rcsb pdb:2KUQ|rcsb pdb:2XB7|rcsb pdb:2XBA|rcsb pdb:2XP2|rcsb pdb:2YFX|rcsb pdb:2YHV|rcsb pdb:2YJR|rcsb pdb:2YJS|rcsb pdb:2YS5|rcsb pdb:2YT2|rcsb pdb:3L9P|rcsb pdb:3LCS|rcsb pdb:3LCT|rcsb pdb:4ANL|rcsb pdb:4ANQ|rcsb pdb:4ANS|rcsb pdb:4CCB|rcsb pdb:4CCU|rcsb pdb:4CD0|rcsb pdb:3AOX|rcsb pdb:4CLI|rcsb pdb:4CLJ|rcsb pdb:4CMO|rcsb pdb:4CMT|rcsb pdb:4CMU|rcsb pdb:4CNH|rcsb pdb:4CTB|rcsb pdb:4CTC|rcsb pdb:4DCE|rcsb pdb:4FNW|rcsb pdb:4FNX|rcsb pdb:4FNY|rcsb pdb:4FNZ|rcsb pdb:4FOB|rcsb pdb:4FOC|rcsb pdb:4FOD|rcsb pdb:4JOA|rcsb pdb:4MKC|rcsb pdb:4TT7|rcsb pdb:4Z55|rcsb pdb:5A9U|rcsb pdb:5AA9|rcsb pdb:5AAA|rcsb pdb:5AAB|rcsb pdb:5AAC|rcsb pdb:5FTO|rcsb pdb:5FTQ|rcsb pdb:5IMX|rcsb pdb:5IUG|rcsb pdb:5IUH|rcsb pdb:5IUI|rcsb pdb:5KZ0|rcsb pdb:5VZ5|rcsb pdb:6AT9|rcsb pdb:6CDT|rcsb pdb:6E0R|rcsb pdb:6EBW|rcsb pdb:6EDL|rcsb pdb:6MX8|rcsb pdb:7BTT|rcsb pdb:7JY4|rcsb pdb:7JYR|rcsb pdb:7JYS|rcsb pdb:7JYT|rcsb pdb:5AA8|refseq:NP_004295.2|dip:DIP-5954N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:AVut3q3smPUsklP/IahGM8qzDM49606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q15286	-	intact:EBI-722275|uniprotkb:B4E390|uniprotkb:B2R6E0|ensembl:ENSP00000229340	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:rab35_human(display_long)|uniprotkb:Ras-related protein Rab-1C(gene name synonym)|uniprotkb:GTP-binding protein RAY(gene name synonym)|uniprotkb:RAB35(gene name)|psi-mi:RAB35(display_short)|uniprotkb:RAB1C(gene name synonym)|uniprotkb:RAY(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001161078.1|refseq:NP_006852.1|ensembl:ENSG00000111737(gene)|ensembl:ENST00000229340(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042470"(melanosome)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|mint:Q15286|rcsb pdb:3TW8|rcsb pdb:6EKK|rcsb pdb:6IF2|rcsb pdb:6IF3|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo9606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P45985	-	intact:EBI-447868|uniprotkb:D3DTS5|uniprotkb:Q5U0B8|uniprotkb:B2R7N7|uniprotkb:B3KYB2|uniprotkb:Q6FHX4|uniprotkb:Q6P9H2|uniprotkb:Q6PIE6|intact:EBI-28973354|ensembl:ENSP00000262445	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:mp2k4_human(display_long)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:MAP2K4(gene name)|psi-mi:MAP2K4(display_short)|uniprotkb:JNKK1(gene name synonym)|uniprotkb:MKK4(gene name synonym)|uniprotkb:PRKMK4(gene name synonym)|uniprotkb:SERK1(gene name synonym)|uniprotkb:MEK4(gene name synonym)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:SKK1(gene name synonym)|uniprotkb:SEK1(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-968188	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_003001.1|ensembl:ENSP00000262445|ensembl:ENST00000415385|ensembl:ENSP00000410402|refseq:NP_001268364.1|ensembl:ENST00000353533(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072709"(cellular response to sorbitol)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P45985|rcsb pdb:3ALN|rcsb pdb:3ALO|rcsb pdb:3VUT|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-5210891|reactome:R-HSA-5684264|ensembl:ENSG00000065559(gene)	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the alk part of the NPM-ALK protein were used in the immunoprecipitation.|figure legend:Table 2|comment:"GI:18569024 which forms part of the purified complex could not be mapped to UniProt entry."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2020/06/18	-	rogid:/ndhkIbnc9oTm68r4DwDUyfXDF89606	intact-crc:2C1EED1AC95BD131	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q9BPX3	-	intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:G45XQBcnTeSunRz57s6lJErxvjo9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q08752	-	intact:EBI-716596|uniprotkb:B2R9V2|ensembl:ENSP00000303754	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:ppid_human(display_long)|uniprotkb:Cyclophilin-40(gene name synonym)|uniprotkb:Cyclophilin-related protein(gene name synonym)|uniprotkb:PPID(gene name)|psi-mi:PPID(display_short)|uniprotkb:CYP40(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)|uniprotkb:40 kDa peptidyl-prolyl cis-trans isomerase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_005029.1|ensembl:ENSG00000171497(gene)|ensembl:ENST00000307720(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0015031"(protein transport)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071492"(cellular response to UV-A)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|reactome:R-HSA-8939211|interpro:IPR011990(Tetratricopeptide-like helical)|dip:DIP-34893N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:Vw7y4LTw7d9HE3txHGqBM0NEY5Q9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P52948	-	intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q14451	-	intact:EBI-970191|ensembl:ENSP00000310771|ensembl:ENSP00000377759|ensembl:ENSP00000377761|uniprotkb:B2RAV1|uniprotkb:B3KNL0|uniprotkb:B3KWP9|uniprotkb:B7WP75|uniprotkb:Q53YD3|uniprotkb:Q9Y220|uniprotkb:Q92568|uniprotkb:Q96DF9|intact:EBI-1257061|uniprotkb:J3KQM4	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:grb7_human(display_long)|uniprotkb:GRB7(gene name)|psi-mi:GRB7(display_short)|uniprotkb:GRB7 adapter protein(gene name synonym)|uniprotkb:Epidermal growth factor receptor GRB-7(gene name synonym)|uniprotkb:B47(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000141738(gene)|ensembl:ENST00000309156(transcript)|ensembl:ENST00000394209(transcript)|ensembl:ENST00000394211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042995"(cell projection)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015042("BPS (Between PH and SH2)")|interpro:IPR029071|interpro:IPR035032|interpro:IPR036860|interpro:IPR039664|interpro:IPR039665|mint:Q14451|rcsb pdb:1MW4|rcsb pdb:1WGR|rcsb pdb:2L4K|rcsb pdb:2QMS|rcsb pdb:3PQZ|rcsb pdb:4WWQ|rcsb pdb:4X6S|rcsb pdb:5D0J|rcsb pdb:5EEL|rcsb pdb:5EEQ|rcsb pdb:5TYI|rcsb pdb:5U06|rcsb pdb:5U1Q|go:"GO:0042802"(identical protein binding)|reactome:R-HSA-1306955|reactome:R-HSA-186763|reactome:R-HSA-210993|reactome:R-HSA-8853659|reactome:R-HSA-9696273|reactome:R-HSA-1433557|refseq:NP_001025173.1|refseq:NP_001229371.1|refseq:NP_001229372.1|refseq:NP_005301.2|refseq:NP_001317136.1|dip:DIP-502N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:XViWZjk5YwdZFTG3zs2aNdxeFVQ9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q99963	-	intact:EBI-473910|uniprotkb:O43553|uniprotkb:O43554|ensembl:ENSP00000391372	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:sh3g3_human(display_long)|uniprotkb:Endophilin-3(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 3(gene name synonym)|uniprotkb:SH3 domain protein 2C(gene name synonym)|uniprotkb:EEN-B2(gene name synonym)|uniprotkb:SH3GL3(gene name)|psi-mi:SH3GL3(display_short)|uniprotkb:CNSA3(gene name synonym)|uniprotkb:SH3D2C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001288037.1|refseq:NP_001288038.1|ensembl:ENSG00000140600(gene)|ensembl:ENST00000427482(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0006897"(endocytosis)|rcsb pdb:2Z0V|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9031628|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0098793"(presynapse)|go:"GO:0098845"(postsynaptic endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0031901"(early endosome membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR032469|interpro:IPR035824|interpro:IPR036028|mint:Q99963|rcsb pdb:2EW3|refseq:NP_003018.3|refseq:XP_011520191.1|refseq:NP_001311112.1|refseq:NP_001311114.1|refseq:NP_001311116.1|refseq:XP_016877975.1|dip:DIP-34766N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:0MBJt+lIGr7wul+tAItvkg4LqIQ9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P51532	-	intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q14980	-	intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q8WXD9	-	intact:EBI-970261|ensembl:ENSP00000345436|uniprotkb:Q9P2P0	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:cski1_human(display_long)|uniprotkb:CASKIN1(gene name)|psi-mi:CASKIN1(display_short)|uniprotkb:KIAA1306(gene name synonym)|uniprotkb:CASK-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000167971(gene)|ensembl:ENST00000343516(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR027013|interpro:IPR032117|interpro:IPR032232|interpro:IPR035495|interpro:IPR035497|interpro:IPR035498|interpro:IPR036028|interpro:IPR036770|rcsb pdb:3SEI|rcsb pdb:3SEN|rcsb pdb:7ATY|refseq:NP_065815.1|dip:DIP-34890N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:Dwn+HTlOEcw3GesOlBoVu/GksJM9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:O60729	-	intact:EBI-970231|ensembl:ENSP00000364389|uniprotkb:A6N5X8|uniprotkb:O43183|uniprotkb:O60730|uniprotkb:Q5JU08|uniprotkb:B1AL31|uniprotkb:B1AL32|uniprotkb:A8MQ20	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:cc14b_human(display_long)|uniprotkb:CDC14B(gene name)|psi-mi:CDC14B(display_short)|uniprotkb:CDC14 cell division cycle 14 homolog B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000081377(gene)|ensembl:ENST00000375241(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|mint:O60729|rcsb pdb:1OHC|rcsb pdb:1OHD|rcsb pdb:1OHE|reactome:R-HSA-5687128|refseq:NP_003662.1|refseq:NP_201588.1|refseq:XP_011517460.1|refseq:NP_001070649.1|refseq:XP_016870732.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:b0+v+nN2fk9Eo6xMg0SlaXHWQAA9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:P49454	-	intact:EBI-968343|ensembl:ENSP00000355922|uniprotkb:Q13171|uniprotkb:Q13246|uniprotkb:Q5VVM7|intact:EBI-2563723|intact:EBI-21028103	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:cenpf_human(display_long)|uniprotkb:CENPF(gene name)|psi-mi:CENPF(display_short)|uniprotkb:Kinetochore protein CENPF(gene name synonym)|uniprotkb:Mitosin(gene name synonym)|uniprotkb:AH antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970278	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000117724(gene)|ensembl:ENST00000366955(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0001822"(kidney development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0042493"|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR018302|interpro:IPR018463|interpro:IPR019513|interpro:IPR043513|mint:P49454|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-156711|refseq:NP_057427.3|refseq:XP_016855575.1	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Antibodies raised specifically against the NPM part of the protein were used to detect this interaction.|figure legend:Table 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2019/01/23	-	rogid:gPlJiOCF1/MAVT80oKwlQlLgluo9606	intact-crc:0F4D6AC63E715F9B	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
intact:EBI-1108795	uniprotkb:Q13233	-	intact:EBI-49776|ensembl:ENSP00000382423	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:m3k1_human(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:MAP3K1(gene name)|psi-mi:MAP3K1(display_short)|uniprotkb:MAPKKK1(gene name synonym)|uniprotkb:MEKK(gene name synonym)|uniprotkb:MEKK1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970373	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_005912.1|ensembl:ENSP00000382423|dip:DIP-27520N|ensembl:ENSG00000095015(gene)|ensembl:ENST00000399503(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13233|rcsb pdb:6WHB|reactome:R-HSA-166058|reactome:R-HSA-2871796|reactome:R-HSA-933542|reactome:R-HSA-975138|reactome:R-HSA-975871	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:5|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:kxdotY9M7Rd4Xr4IIlf7NVv7AC89606	intact-crc:BA820EA1ED6DD066	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P19174	-	intact:EBI-79387|uniprotkb:Q2V575|uniprotkb:B9EGH4|uniprotkb:B7ZLY7|uniprotkb:E1P5W4|intact:EBI-3959906|ensembl:ENSP00000362368	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:plcg1_human(display_long)|uniprotkb:PLC-148(gene name synonym)|uniprotkb:PLC1(gene name synonym)|uniprotkb:Phospholipase C-II(gene name synonym)|uniprotkb:PLCG1(gene name)|psi-mi:PLCG1(display_short)|uniprotkb:Phosphoinositide phospholipase C-gamma-1(gene name synonym)|uniprotkb:Phospholipase C-gamma-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970373	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_002651.2|refseq:NP_877963.1|dip:DIP-100N|ensembl:ENSG00000124181(gene)|ensembl:ENST00000373271(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0050429"(calcium-dependent phospholipase C activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028380|interpro:IPR035023|interpro:IPR035024|interpro:IPR035724|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|mint:P19174|rcsb pdb:1HSQ|rcsb pdb:2HSP|rcsb pdb:4EY0|rcsb pdb:4FBN|rcsb pdb:7NXE|reactome:R-HSA-1169408|reactome:R-HSA-1236382|reactome:R-HSA-1251932|reactome:R-HSA-1489509|reactome:R-HSA-167021|reactome:R-HSA-1855204|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029485|reactome:R-HSA-210990|reactome:R-HSA-212718|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-418890|reactome:R-HSA-5218921|reactome:R-HSA-5637810|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9026527|reactome:R-HSA-9027277|reactome:R-HSA-9034793|reactome:R-HSA-9664323|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:5|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:pJsNLrqg3cUj0SdjoyLf+/91yBo9606	intact-crc:BA820EA1ED6DD066	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P45985	-	intact:EBI-447868|uniprotkb:D3DTS5|uniprotkb:Q5U0B8|uniprotkb:B2R7N7|uniprotkb:B3KYB2|uniprotkb:Q6FHX4|uniprotkb:Q6P9H2|uniprotkb:Q6PIE6|intact:EBI-28973354|ensembl:ENSP00000262445	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:mp2k4_human(display_long)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:MAP2K4(gene name)|psi-mi:MAP2K4(display_short)|uniprotkb:JNKK1(gene name synonym)|uniprotkb:MKK4(gene name synonym)|uniprotkb:PRKMK4(gene name synonym)|uniprotkb:SERK1(gene name synonym)|uniprotkb:MEK4(gene name synonym)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:SKK1(gene name synonym)|uniprotkb:SEK1(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970373	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_003001.1|ensembl:ENSP00000262445|ensembl:ENST00000415385|ensembl:ENSP00000410402|refseq:NP_001268364.1|ensembl:ENST00000353533(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072709"(cellular response to sorbitol)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P45985|rcsb pdb:3ALN|rcsb pdb:3ALO|rcsb pdb:3VUT|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-5210891|reactome:R-HSA-5684264|ensembl:ENSG00000065559(gene)	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:5|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:/ndhkIbnc9oTm68r4DwDUyfXDF89606	intact-crc:BA820EA1ED6DD066	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P21709	-	intact:EBI-968453|ensembl:ENSP00000275815|ensembl:ENSP00000494931|uniprotkb:B5A966|uniprotkb:B5A967|uniprotkb:Q15405|uniprotkb:A1L3V3	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:epha1_human(display_long)|uniprotkb:EPHA1(gene name)|psi-mi:EPHA1(display_short)|uniprotkb:EPH(gene name synonym)|uniprotkb:EPHT(gene name synonym)|uniprotkb:EPHT1(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH(gene name synonym)|uniprotkb:EPH tyrosine kinase(gene name synonym)|uniprotkb:EPH tyrosine kinase 1(gene name synonym)|uniprotkb:Erythropoietin-producing hepatoma receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970373	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000146904(gene)|ensembl:ENSG00000284816(gene)|ensembl:ENST00000275815(transcript)|ensembl:ENST00000645847(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034251|interpro:IPR036116|mint:P21709|rcsb pdb:2K1K|rcsb pdb:2K1L|rcsb pdb:3HIL|rcsb pdb:3KKA|reactome:R-HSA-2682334|reactome:R-HSA-2892247|reactome:R-HSA-3928663|reactome:R-HSA-3928665|refseq:NP_005223.4|dip:DIP-34886N	omim:105590(see-also)|omim:164040(see-also)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:5|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:TB6kRxNntZnW6eicjTb94922jDM9606	intact-crc:BA820EA1ED6DD066	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P10809	-	intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970381	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	intact-crc:FEA03449C6C6795E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P62993	-	intact:EBI-401755|ensembl:ENSP00000339007|uniprotkb:P29354|uniprotkb:Q14450|uniprotkb:Q63057|uniprotkb:Q63059|ensembl:ENSP00000376345|ensembl:ENSP00000376347|ensembl:ENSP00000496913	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:grb2_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000177885(gene)|refseq:NP_002077.1|refseq:NP_987102.1|ensembl:ENST00000316804(transcript)|ensembl:ENST00000392562(transcript)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|ensembl:ENST00000392564(transcript)|ensembl:ENST00000648046(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0012506"(vesicle membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|mint:P62993|rcsb pdb:1AZE|rcsb pdb:1BM2|rcsb pdb:1BMB|rcsb pdb:1CJ1|rcsb pdb:1FHS|rcsb pdb:1FYR|rcsb pdb:1GCQ|rcsb pdb:1GFC|rcsb pdb:1GFD|rcsb pdb:1GHU|rcsb pdb:1GRI|rcsb pdb:1IO6|rcsb pdb:1JYQ|rcsb pdb:1JYR|rcsb pdb:1JYU|rcsb pdb:1QG1|rcsb pdb:1TZE|rcsb pdb:1X0N|rcsb pdb:1ZFP|rcsb pdb:2AOA|rcsb pdb:2AOB|rcsb pdb:2H46|rcsb pdb:2H5K|rcsb pdb:2HUW|rcsb pdb:2VVK|rcsb pdb:2VWF|rcsb pdb:2W0Z|rcsb pdb:3C7I|rcsb pdb:3IMD|rcsb pdb:3IMJ|rcsb pdb:3IN7|rcsb pdb:3IN8|rcsb pdb:3KFJ|rcsb pdb:3MXC|rcsb pdb:3N7Y|rcsb pdb:3N84|rcsb pdb:3N8M|rcsb pdb:3OV1|rcsb pdb:3OVE|rcsb pdb:3MXY|rcsb pdb:3S8L|rcsb pdb:3S8N|rcsb pdb:3S8O|rcsb pdb:3WA4|rcsb pdb:4P9V|rcsb pdb:4P9Z|rcsb pdb:5CDW|rcsb pdb:6ICG|rcsb pdb:6ICH|rcsb pdb:6SDF|rcsb pdb:6VK2|rcsb pdb:6WM1|rcsb pdb:6WO2|reactome:R-HSA-109704|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2029482|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-388841|reactome:R-HSA-389359|reactome:R-HSA-391160|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8865999|reactome:R-HSA-8875360|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8983432|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028335|reactome:R-HSA-5654689|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9645135|reactome:R-HSA-9664422|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|dip:DIP-29229N	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606	intact-crc:5511124988FC214E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P40763	-	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970393	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	crc64:6C00632211C8012D	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	intact-crc:DC41D6D50262509D	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P35568	-	intact:EBI-517592|intact:EBI-28983786|ensembl:ENSP00000304895	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:irs1_human(display_long)|uniprotkb:IRS1(gene name)|psi-mi:IRS1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_005535.1|ensembl:ENSP00000304895|dip:DIP-523N|ensembl:ENSG00000169047(gene)|ensembl:ENST00000305123(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005901"(caveola)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:P35568|rcsb pdb:1IRS|rcsb pdb:1K3A|rcsb pdb:1QQG|rcsb pdb:2Z8C|rcsb pdb:5U1M|rcsb pdb:6BNT|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-112412|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-2219530|reactome:R-HSA-2428928|reactome:R-HSA-2586552|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-9603381|reactome:R-HSA-982772	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:n/9Epczwu5jOLSKCKhmIgR7CdOw9606	intact-crc:ABDE96B2269C75B1	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P23588	-	intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606	intact-crc:A63735AA93921305	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P21709	-	intact:EBI-968453|ensembl:ENSP00000275815|ensembl:ENSP00000494931|uniprotkb:B5A966|uniprotkb:B5A967|uniprotkb:Q15405|uniprotkb:A1L3V3	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:epha1_human(display_long)|uniprotkb:EPHA1(gene name)|psi-mi:EPHA1(display_short)|uniprotkb:EPH(gene name synonym)|uniprotkb:EPHT(gene name synonym)|uniprotkb:EPHT1(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH(gene name synonym)|uniprotkb:EPH tyrosine kinase(gene name synonym)|uniprotkb:EPH tyrosine kinase 1(gene name synonym)|uniprotkb:Erythropoietin-producing hepatoma receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	ensembl:ENSG00000146904(gene)|ensembl:ENSG00000284816(gene)|ensembl:ENST00000275815(transcript)|ensembl:ENST00000645847(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034251|interpro:IPR036116|mint:P21709|rcsb pdb:2K1K|rcsb pdb:2K1L|rcsb pdb:3HIL|rcsb pdb:3KKA|reactome:R-HSA-2682334|reactome:R-HSA-2892247|reactome:R-HSA-3928663|reactome:R-HSA-3928665|refseq:NP_005223.4|dip:DIP-34886N	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:TB6kRxNntZnW6eicjTb94922jDM9606	intact-crc:9245EA23AE545B7D	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:P54753	-	intact:EBI-968308|ensembl:ENSP00000332118|uniprotkb:Q7Z740	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:ephb3_human(display_long)|uniprotkb:EPHB3(gene name)|psi-mi:EPHB3(display_short)|uniprotkb:ETK2(gene name synonym)|uniprotkb:HEK2(gene name synonym)|uniprotkb:EPH-like tyrosine kinase 2(gene name synonym)|uniprotkb:Tyrosine-protein kinase TYRO6(gene name synonym)|uniprotkb:TYRO6(gene name synonym)|uniprotkb:Embryonic kinase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970413	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034245|interpro:IPR036116|rcsb pdb:3P1I|rcsb pdb:3ZFY|rcsb pdb:5L6O|rcsb pdb:5L6P|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|ensembl:ENSG00000182580(gene)|ensembl:ENST00000330394(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001655"(urogenital system development)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0016477"(cell migration)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0005003"(ephrin receptor activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011641(GCC2 and GCC3)|refseq:NP_004434.2	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:oRkqmq4Kvbf5UvrNDLX+djq+E/I9606	intact-crc:D378AD1A1B8E2F2D	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1108795	uniprotkb:Q13233	-	intact:EBI-49776|ensembl:ENSP00000382423	psi-mi:npm_alk(display_short)|psi-mi:EBI-1108795(display_long)	psi-mi:m3k1_human(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:MAP3K1(gene name)|psi-mi:MAP3K1(display_short)|uniprotkb:MAPKKK1(gene name synonym)|uniprotkb:MEKK(gene name synonym)|uniprotkb:MEKK1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Crockett et al. (2004)	pubmed:14968112	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-970418	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q9UM73(multiple parent)|uniprotkb:P06748(multiple parent)	refseq:NP_005912.1|ensembl:ENSP00000382423|dip:DIP-27520N|ensembl:ENSG00000095015(gene)|ensembl:ENST00000399503(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13233|rcsb pdb:6WHB|reactome:R-HSA-166058|reactome:R-HSA-2871796|reactome:R-HSA-933542|reactome:R-HSA-975138|reactome:R-HSA-975871	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	antibodies:Anti ALK antibodies were used to detect interactions in this CoIP.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-karpas_299)|taxid:9606(Homo sapiens lymphoma cell line)	-	2005/11/22	2014/10/16	-	rogid:kxdotY9M7Rd4Xr4IIlf7NVv7AC89606	intact-crc:A0418AF79C654CCF	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)