#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8NHU6 uniprotkb:O75410 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:"MI:0018"(two hybrid) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 - - - caution:"Clones of TDRD7 (TRAP) interacting with TCC1 were described as C-terminal amino acids 520-708, however protein is 1098 amino acids long. No sequence given to enable discrepency to be corrected."|dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/25 2014/10/16 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:4D370DAFB03C529B|rigid:MiwRbd2VKz+8gwreehFUltiLRAA false binding-associated region:?-? binding-associated region:203-426 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14008 uniprotkb:O75410-6 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 intact:EBI-624278|ensembl:ENSP00000276520 psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:o75410-6(display_long)|uniprotkb:Short(isoform synonym)|uniprotkb:TACC1-S(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000276520(transcript) - - - caution:"Clones of KIAA0097 (ch-TOG) interacting with TCC1 were described as C-terminal amino acids 1776-1980, however protein is 2032 amino acids long. No sequence given to enable discrepency to be corrected."|dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/25 2014/10/16 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 rogid:GqZlv3nb5klrBQoIj7UUtl4vtSk9606 intact-crc:A6B7D142D4BD307F|rigid:SUOzP3Z+DVVFdY3sAFc4uT6NqEg false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UK45 uniprotkb:O75410-6 intact:EBI-348372|ensembl:ENSP00000252622 intact:EBI-624278|ensembl:ENSP00000276520 psi-mi:lsm7_human(display_long)|uniprotkb:LSM7(gene name)|psi-mi:LSM7(display_short) psi-mi:o75410-6(display_long)|uniprotkb:Short(isoform synonym)|uniprotkb:TACC1-S(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624536 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057283.1|interpro:IPR017132(U6 snRNA-associated Sm-like protein LSm7)|interpro:IPR044641|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|ensembl:ENSG00000130332(gene)|ensembl:ENST00000252622(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|dip:DIP-31129N intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000276520(transcript) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/25 2014/10/16 rogid:vT1gI3yzYl37cX++CUGdJowAL909606 rogid:GqZlv3nb5klrBQoIj7UUtl4vtSk9606 intact-crc:51A03E05CA81AD1D|rigid:zi+r2pu5CEZ3VrhafaHRikAp5+c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14008 uniprotkb:O75410-6 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 intact:EBI-624278|ensembl:ENSP00000276520 psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:o75410-6(display_long)|uniprotkb:Short(isoform synonym)|uniprotkb:TACC1-S(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624548 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000276520(transcript) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/25 2014/10/16 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 rogid:GqZlv3nb5klrBQoIj7UUtl4vtSk9606 intact-crc:A45F234437AC1366|rigid:SUOzP3Z+DVVFdY3sAFc4uT6NqEg false glutathione s tranferase tag:?-? myc tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q14008 uniprotkb:O75410-1 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 intact:EBI-624252|ensembl:ENSP00000321703 psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:o75410-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:TACC1-A(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624556 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/25 2014/10/16 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:C8495DBEE1EEBBB2|rigid:YsJXjEm7DASV1nWpAuG2hMyitXQ false glutathione s tranferase tag:?-? ha tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P62308 uniprotkb:O75410-1 intact:EBI-624585|uniprotkb:Q15357|uniprotkb:Q6IB86|ensembl:ENSP00000272348|intact:EBI-1056206|uniprotkb:D6W5G6 intact:EBI-624252|ensembl:ENSP00000321703 psi-mi:ruxg_human(display_long)|uniprotkb:SNRPG(gene name)|psi-mi:SNRPG(display_short)|uniprotkb:PBSCG(gene name synonym)|uniprotkb:Sm protein G(gene name synonym) psi-mi:o75410-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:TACC1-A(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624578 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097526"(spliceosomal tri-snRNP complex)|ensembl:ENSG00000143977(gene)|ensembl:ENST00000272348(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043186"(P granule)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|mint:P62308|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|refseq:NP_003087.1|dip:DIP-34627N intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/25 2014/10/16 rogid:bwbnMaq7QstuUpgUyJtFqzF5J/I9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:3C4252BA48FD35FC|rigid:nt/ql/JHU/iz24wr70fcsShzmIo false glutathione s tranferase tag:?-? ha tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8NHU6 uniprotkb:O75410-1 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-624252|ensembl:ENSP00000321703 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:o75410-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:TACC1-A(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624634 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/25 2014/10/16 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:95BE96F531934412|rigid:MiwRbd2VKz+8gwreehFUltiLRAA false glutathione s tranferase tag:?-? ha tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O75410 uniprotkb:Q14008 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:"MI:0096"(pull down) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-624701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 intact:EBI-624716(see-also) - - comment:"Authors speculate that one of the regions of interaction between TACC1 and chTOG may be indirect, in that TACC1 may be forming dimers. Region 701-805 subsequently shown to directly interact with chTOG (see EBI-624716)"|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/25 2014/10/16 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 intact-crc:07D9F1E9B8B66707|rigid:YsJXjEm7DASV1nWpAuG2hMyitXQ false myc tag:?-?|binding-associated region:422-591,701-805 glutathione s tranferase tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8NHU6 uniprotkb:O75410 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:"MI:0096"(pull down) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 - - - comment:"SPAZ (serine/proline rich AZU-1) domains are not described in InterPro but are in the feature table of the UniProt entry for this protein"|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/07/25 2014/10/16 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:2F854E9B92EB1C36|rigid:MiwRbd2VKz+8gwreehFUltiLRAA false glutathione s tranferase tag:?-? binding-associated region:152-259|myc tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O75410-1 uniprotkb:Q8NHU6 intact:EBI-624252|ensembl:ENSP00000321703 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 psi-mi:o75410-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:TACC1-A(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624604 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2005/07/25 2014/10/16 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 intact-crc:22F08FEE2B38BAE2|rigid:MiwRbd2VKz+8gwreehFUltiLRAA false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O75410-1 uniprotkb:Q14008 intact:EBI-624252|ensembl:ENSP00000321703 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 psi-mi:o75410-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:TACC1-A(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript) ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2005/07/25 2014/10/16 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 intact-crc:B28ED219E0736A9F|rigid:YsJXjEm7DASV1nWpAuG2hMyitXQ false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O14965 uniprotkb:O75410-1 intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251 intact:EBI-624252|ensembl:ENSP00000321703 psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym) psi-mi:o75410-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:TACC1-A(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624664 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2005/07/25 2014/10/16 rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:A7C8B1DC3DA56FED|rigid:PuB1WYi8VB0PYIvWsVLtmq7VLyU false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8NHU6 uniprotkb:O75410 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 - - - comment:"SPAZ (serine/proline rich AZU-1) domains are not described in InterPro but are in the feature table of the UniProt entry for this protein"|dataset:Cancer - Interactions investigated in the context of cancer taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2005/07/25 2014/10/16 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:662727AFD1221D76|rigid:MiwRbd2VKz+8gwreehFUltiLRAA false myc tag:?-? binding-associated region:203-426 - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O75410-1 uniprotkb:Q14008 intact:EBI-624252|ensembl:ENSP00000321703 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 psi-mi:o75410-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:TACC1-A(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript) ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:9606(human-mammary epithelium)|taxid:9606(Human mammary epithelium) - 2005/07/25 2014/10/16 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 intact-crc:BE840D1CB7B56A4A|rigid:YsJXjEm7DASV1nWpAuG2hMyitXQ false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8NHU6 uniprotkb:Q00537 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-624648|uniprotkb:Q8NEB8|ensembl:ENSP00000261211|uniprotkb:B2RCQ2|uniprotkb:A8K1U6 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:cdk17_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 2(gene name synonym)|uniprotkb:CDK17(gene name)|psi-mi:CDK17(display_short)|uniprotkb:PCTK2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-2(gene name synonym)|uniprotkb:Cell division protein kinase 17(gene name synonym)|uniprotkb:PCTAIRE2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-624641 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 ensembl:ENSG00000059758(gene)|ensembl:ENST00000261211(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q00537|refseq:NP_001163935.1|refseq:NP_002586.2|refseq:XP_016874894.1|refseq:XP_016874895.1 - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2005/07/25 2014/10/16 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:G0S58NAdKuGi4GfDHm5hxhGfB249606 intact-crc:DD52F3116A2B8EFF|rigid:kQIMWxvu9U22DA/i1oxaBPWiacw false myc tag:?-? - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8NHU6 uniprotkb:O75410-1 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-624252|ensembl:ENSP00000321703 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:o75410-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:TACC1-A(isoform synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:Taxin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-624641 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 intact:EBI-624237(tacc1_human)|ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2005/07/25 2014/10/16 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:DD52F3116A2B8EFF|rigid:kQIMWxvu9U22DA/i1oxaBPWiacw false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q14008 uniprotkb:O75410 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624716 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 - - - comment:"Authors speculate that one of the regions of interaction between TACC1 and chTOG may be indirect, in that TACC1 may be forming dimers. Region 701-805 subsequently shown to directly interact with chTOG (see EBI-)"|dataset:Cancer - Interactions investigated in the context of cancer taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2005/07/25 2014/10/16 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:6093A2027948D00C|rigid:YsJXjEm7DASV1nWpAuG2hMyitXQ false myc tag:?-? binding-associated region:701-805|ha tag:?-? - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O75410 uniprotkb:Q9UK45 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 intact:EBI-348372|ensembl:ENSP00000252622 psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:lsm7_human(display_long)|uniprotkb:LSM7(gene name)|psi-mi:LSM7(display_short) psi-mi:"MI:0018"(two hybrid) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 refseq:NP_057283.1|interpro:IPR017132(U6 snRNA-associated Sm-like protein LSm7)|interpro:IPR044641|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|ensembl:ENSG00000130332(gene)|ensembl:ENST00000252622(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|dip:DIP-31129N - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/25 2014/10/16 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 rogid:vT1gI3yzYl37cX++CUGdJowAL909606 intact-crc:304988E1D0A2A3C0|rigid:niEHLRp29Cb5OMlxc66sPEMS3R4 false binding-associated region:1-55 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75410 uniprotkb:P62308 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 intact:EBI-624585|uniprotkb:Q15357|uniprotkb:Q6IB86|ensembl:ENSP00000272348|intact:EBI-1056206|uniprotkb:D6W5G6 psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:ruxg_human(display_long)|uniprotkb:SNRPG(gene name)|psi-mi:SNRPG(display_short)|uniprotkb:PBSCG(gene name synonym)|uniprotkb:Sm protein G(gene name synonym) psi-mi:"MI:0018"(two hybrid) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 go:"GO:0097526"(spliceosomal tri-snRNP complex)|ensembl:ENSG00000143977(gene)|ensembl:ENST00000272348(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043186"(P granule)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|mint:P62308|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|refseq:NP_003087.1|dip:DIP-34627N - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/25 2014/10/16 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 rogid:bwbnMaq7QstuUpgUyJtFqzF5J/I9606 intact-crc:D6965ADF4257B235|rigid:nt/ql/JHU/iz24wr70fcsShzmIo false binding-associated region:1-55 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHU6 uniprotkb:O75410 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:"MI:0018"(two hybrid) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-624693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 - - - comment:"SPAZ (serine/proline rich AZU-1) domains are not described in InterPro but are in the feature table of the UniProt entry for this protein"|dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/07/25 2014/10/16 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:BF417DEF03D7BCF7|rigid:MiwRbd2VKz+8gwreehFUltiLRAA false - binding-associated region:203-259 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14965 uniprotkb:Q14008 intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym) psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-624759 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 go:"GO:0051323"(metaphase)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005819"(spindle)|go:"GO:0006445"|go:"GO:0051301"(cell division) - - disease:Cancer - breast|dataset:Cancer - Interactions investigated in the context of cancer taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2005/07/25 2014/10/16 rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 intact-crc:CE78F338FB3635B2|rigid:dXdJ2q0GPw8z5dZ3xXJNeX88rRM false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:O14965 uniprotkb:O75410 intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251 intact:EBI-624237|uniprotkb:Q8IUJ3|uniprotkb:Q8IUJ4|uniprotkb:Q8IZG2|uniprotkb:Q8NEY7|uniprotkb:Q9UPP9|uniprotkb:B2RBD9|uniprotkb:Q6Y687|uniprotkb:Q86YG7|uniprotkb:Q8IUJ2|ensembl:ENSP00000321703|uniprotkb:D3DSX6|uniprotkb:B4E302 psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym) psi-mi:tacc1_human(display_long)|uniprotkb:Taxin-1(gene name synonym)|uniprotkb:Gastric cancer antigen Ga55(gene name synonym)|uniprotkb:TACC1(gene name)|psi-mi:TACC1(display_short)|uniprotkb:KIAA1103(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Conte et al. (2003) pubmed:14603251 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-624759 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U ensembl:ENSG00000147526(gene)|ensembl:ENST00000317827(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030496"(midbody)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051301"(cell division)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O75410|go:"GO:0046966"(thyroid hormone receptor binding)|refseq:NP_001116296.1|refseq:NP_001139688.1|refseq:NP_006274.2|refseq:XP_005273682.1|refseq:XP_011542933.1|refseq:XP_011542934.1|refseq:XP_011542938.1|refseq:XP_016869261.1|refseq:XP_016869262.1|refseq:XP_016869263.1|refseq:XP_011542936.1|refseq:XP_011542939.1 go:"GO:0051323"(metaphase)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005819"(spindle)|go:"GO:0006445"|go:"GO:0051301"(cell division) - - disease:Cancer - breast|dataset:Cancer - Interactions investigated in the context of cancer taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2005/07/25 2014/10/16 rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606 rogid:o/GBmp6rt7B1GgH4gdBNaN5VrSc9606 intact-crc:CE78F338FB3635B2|rigid:dXdJ2q0GPw8z5dZ3xXJNeX88rRM false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)