#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P34760 uniprotkb:P36077 intact:EBI-19623|uniprotkb:D6VZE6|ensemblfungi:YML028W intact:EBI-26774|uniprotkb:D6VXK2|ensemblfungi:YKL086W psi-mi:tsa1_yeast(display_long)|uniprotkb:TSA1(gene name)|psi-mi:TSA1(display_short)|uniprotkb:TPX1(gene name synonym)|uniprotkb:TSA(gene name synonym)|uniprotkb:YML028W(locus name)|uniprotkb:Cytoplasmic thiol peroxidase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein 1(gene name synonym)|uniprotkb:ZRG14(gene name synonym)|uniprotkb:Protector protein(gene name synonym)|uniprotkb:Thioredoxin peroxidase type Ia(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin TSA1(gene name synonym) psi-mi:srx1_yeast(display_long)|uniprotkb:YKL086W(locus name)|uniprotkb:SRX1(gene name)|psi-mi:SRX1(display_short)|uniprotkb:Sulphiredoxin(gene name synonym) psi-mi:"MI:0401"(biochemical) Biteau et al. (2003) pubmed:14586471 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-519253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013684.1|sgd:S000004490|ensemblfungi:YML028W(gene)|ensemblfungi:YML028W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:3SBC|reactome:R-SCE-5628897|reactome:R-SCE-6798695|dip:DIP-1667N|mint:P34760 refseq:NP_012837.1|sgd:S000001569|dip:DIP-4344N|ensemblfungi:YKL086W(gene)|ensemblfungi:YKL086W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0032542"(sulfiredoxin activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR003115(ParB-like nuclease)|interpro:IPR016692(Sulfiredoxin)|interpro:IPR036086 - crc64:9ACF40E410F2C04A - comment:Srx1 forms a transient disulphide bond with Tsa1 during reduction of Tsa1 cysteine-sulphinic acid. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/03/16 2014/10/16 rogid:2kHGj9RnAcSVt34pqwssv9nANPM559292 rogid:ClZSsloB2B3ykSaB45MJvmT0TqY559292 intact-crc:20C8FB37583E91B1|rigid:vVqCrsSuAXzF7LZ6qleaGUcgmTo false - his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)