#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51610	uniprotkb:P11161	intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473	intact:EBI-625282|uniprotkb:Q68CZ5|uniprotkb:Q8IV26|uniprotkb:Q9UNA6|uniprotkb:B3KRD7|uniprotkb:B2R724|ensembl:ENSP00000242480	psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym)	psi-mi:egr2_human(display_long)|uniprotkb:Zinc finger protein Krox-20(gene name synonym)|uniprotkb:AT591(gene name synonym)|uniprotkb:EGR2(gene name)|psi-mi:EGR2(display_short)|uniprotkb:KROX20(gene name synonym)|uniprotkb:E3 SUMO-protein transferase ERG2(gene name synonym)|uniprotkb:Early growth response protein 2(gene name synonym)	psi-mi:"MI:0232"(transcriptional complementation assay)	Luciano et al. (2003)	pubmed:14532282	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-625760	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N	refseq:NP_001307966.1|refseq:NP_000390.2|refseq:NP_001129651.1|refseq:NP_001129649.1|refseq:NP_001129650.1|ensembl:ENSP00000242480|ensembl:ENST00000411732|ensembl:ENSP00000387634|ensembl:ENSG00000122877(gene)|ensembl:ENST00000242480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010467"(gene expression)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016925"(protein sumoylation)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021659"(rhombomere 3 structural organization)|go:"GO:0021660"(rhombomere 3 formation)|go:"GO:0021665"(rhombomere 5 structural organization)|go:"GO:0021666"(rhombomere 5 formation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032868"(response to insulin)|go:"GO:0035284"(brain segmentation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042552"(myelination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR021849|interpro:IPR036236|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-9031628|reactome:R-HSA-9619665	-	-	-	comment:"The beta-propeller of hcfc1 was able to activate the reporter gene when coexpressed with either full-length or n-terminus region (AA 1-170) of egr2. The specificity of this interaction was verified using the tsBN67 version of the hcfc1 beta-propeller which contains a pro134ser mutation. Activation was not observed using the P134S mutant indicating that recruitment of egr2 to the promoter was dependant on a functional beta-propeller."	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/07/26	2014/10/16	rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606	rogid:J2XtPrvkDyR6kAQRiWzY2AUL0+49606	intact-crc:E642F9F5BD38206A|rigid:mRBmkagnseDnRQ5FKwNB+sBr8uc	false	sufficient binding region:1-380|binding-associated region:134-134|tag:?-?	sufficient binding region:1-170	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)