#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9HB21 uniprotkb:Q12923 intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym) psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032407|mint:MINT-65960 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679(gene)|ensembl:ENST00000368990(transcript)|ensembl:ENST00000392799(transcript)|ensembl:ENST00000433307(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-1660499|rcsb pdb:1EAZ|refseq:XP_005270073.1|refseq:XP_005270078.1|ensembl:ENST00000368988|ensembl:ENSP00000357984|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416|mint:MINT-740674(identity) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-740683(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:homomint|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 intact-crc:5B174056D934A2A0|rigid:/PZDGROMtJ2lmvkCY8WdQFa229U false tag:?-?(MINT-740678)|binding-associated region:401-404(MINT-740675) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HB19 uniprotkb:Q12923 intact:EBI-4401947 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 psi-mi:pkha2_human(display_long)|uniprotkb:PLEKHA2(gene name)|psi-mi:PLEKHA2(display_short)|uniprotkb:TAPP2(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 2(gene name synonym) psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032427|mint:MINT-65961 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067636.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|reactome:R-HSA-1660499|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|mint:MINT-740658(identity) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-740667(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:homomint|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:gaDNQEdJ1GwHMQcxHJxP+GIaaXE9606 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 intact-crc:B37A6DEE24E4E0AA|rigid:VHIiS/wrc37A/4zFdZPW/0JV6is false tag:?-?(MINT-740662)|binding-associated region:301-304(MINT-740659) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HB21 uniprotkb:O75970 intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|intact:EBI-10961605|uniprotkb:B2RTS3|ensembl:ENSP00000320006 psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym) psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym) psi-mi:"MI:0096"(pull down) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032463|mint:MINT-65962 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679(gene)|ensembl:ENST00000368990(transcript)|ensembl:ENST00000392799(transcript)|ensembl:ENST00000433307(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-1660499|rcsb pdb:1EAZ|refseq:XP_005270073.1|refseq:XP_005270078.1|ensembl:ENST00000368988|ensembl:ENSP00000357984|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416|mint:MINT-740636(identity) refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:NP_003820.2|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:XP_016870742.1|ensembl:ENSG00000107186(gene)|ensembl:ENST00000319217(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1|mint:MINT-740627(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606 rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606 intact-crc:05FE3A893E7B6173|rigid:ZXHh3xxO/SrTvaCHmU9k/I03+jo false tag:?-?(MINT-740637) tag:?-?(MINT-740631)|binding-associated region:1987-2069(MINT-740628) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12923 uniprotkb:Q9HB21 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032528|mint:MINT-65966 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-740757(identity) refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679(gene)|ensembl:ENST00000368990(transcript)|ensembl:ENST00000392799(transcript)|ensembl:ENST00000433307(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-1660499|rcsb pdb:1EAZ|refseq:XP_005270073.1|refseq:XP_005270078.1|ensembl:ENST00000368988|ensembl:ENSP00000357984|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416|mint:MINT-740766(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5B|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606 intact-crc:0A56097C2C620B52|rigid:/PZDGROMtJ2lmvkCY8WdQFa229U false binding-associated region:1099-1199(MINT-740758) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75970 uniprotkb:Q9HB19 intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|intact:EBI-10961605|uniprotkb:B2RTS3|ensembl:ENSP00000320006 intact:EBI-4401947 psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym) psi-mi:pkha2_human(display_long)|uniprotkb:PLEKHA2(gene name)|psi-mi:PLEKHA2(display_short)|uniprotkb:TAPP2(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032487|mint:MINT-65963 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:NP_003820.2|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:XP_016870742.1|ensembl:ENSG00000107186(gene)|ensembl:ENST00000319217(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1|mint:MINT-740690(identity) refseq:NP_067636.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|reactome:R-HSA-1660499|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|mint:MINT-740699(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606 rogid:gaDNQEdJ1GwHMQcxHJxP+GIaaXE9606 intact-crc:D8397855C0DDD789|rigid:29sRvpCSeJUMt6/6bF/5YI/UCwE false binding-associated region:1987-2069(MINT-740691)|tag:?-?(MINT-740694) tag:?-?(MINT-740700) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12923 uniprotkb:Q9HB21 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032567|mint:MINT-65968 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-740609(identity) refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679(gene)|ensembl:ENST00000368990(transcript)|ensembl:ENST00000392799(transcript)|ensembl:ENST00000433307(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-1660499|rcsb pdb:1EAZ|refseq:XP_005270073.1|refseq:XP_005270078.1|ensembl:ENST00000368988|ensembl:ENSP00000357984|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416|mint:MINT-740618(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5B|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606 intact-crc:23407136757F063F|rigid:/PZDGROMtJ2lmvkCY8WdQFa229U false binding-associated region:1088-1990(MINT-740610)|tag:?-?(MINT-740613) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HB19 uniprotkb:Q12923 intact:EBI-4401947 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 psi-mi:pkha2_human(display_long)|uniprotkb:PLEKHA2(gene name)|psi-mi:PLEKHA2(display_short)|uniprotkb:TAPP2(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 2(gene name synonym) psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032546|mint:MINT-65967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067636.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|reactome:R-HSA-1660499|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|mint:MINT-740717(identity) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-740708(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5C|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:gaDNQEdJ1GwHMQcxHJxP+GIaaXE9606 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 intact-crc:7D988F399ADC0579|rigid:VHIiS/wrc37A/4zFdZPW/0JV6is false - tag:?-?(MINT-740712)|binding-associated region:1099-1199(MINT-740709) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12923 uniprotkb:Q9HB21 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032666|mint:MINT-65964 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-740750(identity) refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679(gene)|ensembl:ENST00000368990(transcript)|ensembl:ENST00000392799(transcript)|ensembl:ENST00000433307(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-1660499|rcsb pdb:1EAZ|refseq:XP_005270073.1|refseq:XP_005270078.1|ensembl:ENST00000368988|ensembl:ENSP00000357984|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416|mint:MINT-740746(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4B|comment:homomint|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606 intact-crc:1BE7E49BC780E62E|rigid:/PZDGROMtJ2lmvkCY8WdQFa229U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12923 uniprotkb:Q9HB21 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7032695|mint:MINT-65965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-740651(identity) refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679(gene)|ensembl:ENST00000368990(transcript)|ensembl:ENST00000392799(transcript)|ensembl:ENST00000433307(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-1660499|rcsb pdb:1EAZ|refseq:XP_005270073.1|refseq:XP_005270078.1|ensembl:ENST00000368988|ensembl:ENSP00000357984|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416|mint:MINT-740647(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4B|comment:homomint|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606 intact-crc:1F4B90F71C49ADBB|rigid:/PZDGROMtJ2lmvkCY8WdQFa229U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HB21 uniprotkb:Q12923 intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym) psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kimber et al. (2003) pubmed:14516276|mint:MINT-5216728 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7032755|mint:MINT-65969 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679(gene)|ensembl:ENST00000368990(transcript)|ensembl:ENST00000392799(transcript)|ensembl:ENST00000433307(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-1660499|rcsb pdb:1EAZ|refseq:XP_005270073.1|refseq:XP_005270078.1|ensembl:ENST00000368988|ensembl:ENSP00000357984|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416|mint:MINT-740735(identity) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|mint:MINT-740728(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6A|comment:homomint|comment:mint|partial coverage:partial coverage taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/10/13 2014/10/16 rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 intact-crc:DE006DE4547FB13B|rigid:/PZDGROMtJ2lmvkCY8WdQFa229U false yellow fluorescent protein tag:?-?(MINT-740738) mutation disrupting interaction:211-211(MINT-5206353)|ha tag:?-?(MINT-740729) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0707"(anti tag immunostaining)