#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04637-1	uniprotkb:P03126	intact:EBI-3895849|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-7137141|intact:EBI-7137188|intact:EBI-7203190|intact:EBI-7009236|intact:EBI-8552534|intact:EBI-8628913|intact:EBI-7009202|intact:EBI-8552575|intact:MINT-91160|intact:EBI-7203248|intact:EBI-7203213	intact:EBI-1177242|uniprotkb:Q71BI7	psi-mi:p04637-1(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:p53(isoform synonym)|uniprotkb:p53alpha(isoform synonym)	psi-mi:ve6_hpv16(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Scheffner et al. (1992)	pubmed:1321290|mint:MINT-5216689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009196|mint:MINT-69729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|intact:EBI-366083(isoform-parent)|uniprotkb:P04637-1(isoform-parent)|mint:MINT-740064(identity)	refseq:NP_041325.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:1VZN|rcsb pdb:2FK4|rcsb pdb:2KPL|rcsb pdb:2LJX|rcsb pdb:2LJY|rcsb pdb:2LJZ|rcsb pdb:4GIZ|rcsb pdb:4JOP|rcsb pdb:4XR8|rcsb pdb:6HKS|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|mint:P03126|dip:DIP-44706N|mint:MINT-740059(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1 T1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/18	2014/10/16	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:m9USUwG2VskhrMAdtZ9gSULmGBY333760	intact-crc:EE0DDE10F456958E|rigid:fXi8HoyNbTCLfO0/HczNmytJuxs	false	mutation decreasing interaction:135-135,154-154,266-266,277-277(MINT-740065)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P04637-1	uniprotkb:P03070	intact:EBI-3895849|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-7137141|intact:EBI-7137188|intact:EBI-7203190|intact:EBI-7009236|intact:EBI-8552534|intact:EBI-8628913|intact:EBI-7009202|intact:EBI-8552575|intact:MINT-91160|intact:EBI-7203248|intact:EBI-7203213	intact:EBI-617698	psi-mi:p04637-1(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:p53(isoform synonym)|uniprotkb:p53alpha(isoform synonym)	psi-mi:lt_sv40(display_long)	psi-mi:"MI:0019"(coimmunoprecipitation)	Scheffner et al. (1992)	pubmed:1321290|mint:MINT-5216689	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1891767(sv40)|taxid:1891767(sv40)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009230|mint:MINT-69730	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|intact:EBI-366083(isoform-parent)|uniprotkb:P04637-1(isoform-parent)|mint:MINT-740045(identity)	go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus,  C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N|mint:MINT-740040(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1 T1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/18	2019/10/18	rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606	rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767	intact-crc:8D0C4CDBF559D13C|rigid:VZOTDTO282G04bb2R4V1QRGy4IU	false	mutation decreasing interaction:154-154,266-266,273-273,277-277,135-135(MINT-740046)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)