#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92902	uniprotkb:Q9NQG7	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	-	-	-	comment:Cells are stably transfected with HA-HPS1	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	intact-crc:884D9D970F824406|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	ha tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92902	uniprotkb:Q9NQG7	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704415	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	-	-	-	comment:Cells are stably transfected with myc-HPS4	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	intact-crc:8324033C62209080|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	-	myc tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92902	uniprotkb:Q9NQG7	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704445	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	-	-	-	comment:Proteins are endogenous	taxid:9606(human-mnt-1)|taxid:9606(Homo sapiens melanoma cell line)	-	2005/11/02	2014/10/16	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	intact-crc:31C548D7702A6CA4|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92902	uniprotkb:Q9NQG7	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704450	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	-	-	-	comment:Proteins are endogenous	taxid:9606(human-mnt-1)|taxid:9606(Homo sapiens melanoma cell line)	-	2005/11/02	2014/10/16	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	intact-crc:AD6238920AC6E172|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQG7	uniprotkb:Q92902	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704422	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	-	-	-	comment:Cells are stably transfected with HA-HPS1 and myc-HPS4	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	intact-crc:E303F1A790465DF7|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92902	uniprotkb:Q9NQG7	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	-	-	-	comment:Cells are stably transfected with HA-HPS1 and myc-HPS4	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	intact-crc:4CB559BDD4A15D5A|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQG7	uniprotkb:Q92902	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	go:"GO:0005737"(cytoplasm)	-	-	comment:Cells are transciently transfected with HA-HPS1 and myc-HPS4|comment:The velocity fractions were analyzed first by immunoprecipitation against myc-HPS4 and second by western blotting analysis of HA-HPS1|complex-properties:The sedimentation coefficient is 6.3 S	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	intact-crc:93626908E5CAD261|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQG7	uniprotkb:Q92902	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	go:"GO:0005737"(cytoplasm)	-	-	comment:Cells are transciently transfected with HA-HPS1 and myc-HPS4|comment:The velocity fractions were analyzed first by immunoprecipitation against HA-HPS1 and second by western blotting analysis of myc-HPS4|complex-properties:The sedimentation coefficient is 6.3 S	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	intact-crc:3B26F6FAB249B97E|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQG7	uniprotkb:Q92902	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	-	-	-	comment:Cells are transciently transfected with HA-HPS1 and myc-HPS4|comment:The velocity fractions were analyzed first by immunoprecipitation against myc-HPS4 and second by western blotting analysis of HA-HPS1	taxid:9606(human-mnt-1)|taxid:9606(Homo sapiens melanoma cell line)	-	2005/11/02	2014/10/16	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	intact-crc:B3166E0B7D0234DE|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQG7	uniprotkb:Q92902	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	-	-	-	comment:Cells are transciently transfected with HA-HPS1 and myc-HPS4|comment:The velocity fractions were analyzed first by immunoprecipitation against HA-HPS1 and second by western blotting analysis of Myc-HPS4	taxid:9606(human-mnt-1)|taxid:9606(Homo sapiens melanoma cell line)	-	2005/11/02	2014/10/16	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	intact-crc:D7A36A92EBDC1DC7|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQG7	uniprotkb:Q92902	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704492	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	-	-	-	comment:Cells are stably transfected with HA-HPS1 and myc-HPS4|complex-properties:The calculated molecular mass of the complex is ~175 kDa, which approximates the sum of the molecular maasses of the HSP1 and HSP4 polypeptides. the frictional ratio of ~1.8 indicates that is a moderately asymmetric complex.	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	intact-crc:63C88031CDCE610F|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92902	uniprotkb:Q9NQG7	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704517	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	-	-	-	comment:Cells are stably transfected with HA-HPS1 and myc-HPS4|comment:The size exclusion fractions were analyzed first by immunoprecipitation against myc-HPS4 and second by western blotting analysis of HA-HPS-1	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	intact-crc:66564E1A56833A4D|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQG7	uniprotkb:Q92902	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	-	-	-	comment:Cells are stably transfected with HA-HPS1 and myc-HPS4|comment:The size exlusion fractions were analyzed first by immunoprecipitation against myc-HPS1 and second by western blotting analysis of HA-HPS4	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	intact-crc:218AC658DC49DF90|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92902	uniprotkb:Q9NQG7	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704556	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	-	-	-	comment:Cells are transciently transfected with HA-HPS1 and myc-HPS4	taxid:9606(human-m1)|taxid:9606(Homo sapiens fibroblast cell line)	-	2005/11/02	2014/10/16	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	intact-crc:50EF494C933D3115|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NQG7	uniprotkb:Q92902	intact:EBI-704377|uniprotkb:Q5H8V6|uniprotkb:Q96LX6|uniprotkb:Q9BY93|uniprotkb:Q9UH37|uniprotkb:Q9UH38|uniprotkb:B1AHQ4|ensembl:ENSP00000338457|ensembl:ENSP00000381213	intact:EBI-704347|uniprotkb:A8MRT2|uniprotkb:O15402|uniprotkb:O15502|uniprotkb:Q5TAA3|uniprotkb:Q8WXE5|ensembl:ENSP00000326649|ensembl:ENSP00000355310	psi-mi:hps4_human(display_long)|uniprotkb:Light-ear protein homolog(gene name synonym)|uniprotkb:HPS4(gene name)|psi-mi:HPS4(display_short)|uniprotkb:KIAA1667(gene name synonym)	psi-mi:hps1_human(display_long)|uniprotkb:HPS1(gene name)|psi-mi:HPS1(display_short)|uniprotkb:HPS(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Martina et al. (2003)	pubmed:12756248	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704564	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071364.4|refseq:NP_690054.1|refseq:XP_016884531.1|refseq:XP_016884532.1|refseq:XP_016884533.1|ensembl:ENSP00000338457|ensembl:ENSP00000381213|ensembl:ENST00000402105|ensembl:ENSP00000384185|ensembl:ENSG00000100099(gene)|ensembl:ENST00000336873(transcript)|ensembl:ENST00000398145(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007040"(lysosome organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0007599"(hemostasis)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042827"(platelet dense granule)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048075"(positive regulation of eye pigmentation)|go:"GO:0050821"(protein stabilization)|go:"GO:1903232"(melanosome assembly)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR026091|interpro:IPR043987|interpro:IPR043989|reactome:R-HSA-8876198	refseq:NP_000186.2|refseq:NP_872577.1|refseq:XP_005269814.1|refseq:NP_001309405.1|refseq:NP_001309406.1|refseq:NP_001309407.1|refseq:NP_001309408.1|ensembl:ENSG00000107521(gene)|ensembl:ENST00000325103(transcript)|ensembl:ENST00000361490(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007601"(visual perception)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031085"(BLOC-3 complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050896"(response to stimulus)|go:"GO:1903232"(melanosome assembly)|interpro:IPR026053|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-8876198	-	-	-	comment:Cells are transciently transfected with HA-HPS1 and myc-HPS4	taxid:9606(human-mnt-1)|taxid:9606(Homo sapiens melanoma cell line)	-	2005/11/02	2014/10/16	rogid:VE5iGhD6vzr9dPNHgiAeK2G05Ik9606	rogid:Gxa0wiFS4pOWy9dRTgcXNm5BiQI9606	intact-crc:F01F924DB4CDE4A4|rigid:yU7eHQoz5mivFs+ClQ8zpObOrXQ	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)