#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43351	uniprotkb:Q14191	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/07	2014/10/16	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	intact-crc:D7A674E633A30509|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	-	sufficient binding region:982-1432	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43351	uniprotkb:P43351	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:"MI:0018"(two hybrid)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706466	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/07	2014/10/16	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	intact-crc:2941B909EE2C0BF6|rigid:mTBFXy9cSoK7/MNzyAIwb4HsoT4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43351	uniprotkb:Q06609	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/07	2014/10/16	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	intact-crc:40840A07252B66D2|rigid:x498yLZVdCz0lJQ3P1jyjxIZdIU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43351	uniprotkb:Q14191	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706482	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	-	-	-	comment:"The protein WRN used as the probe (bait) was found both at the location of RAD52 monomers and mulitimers bands"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	intact-crc:1F31BF8212CDFD1C|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43351	uniprotkb:Q14191	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	intact-crc:8DFB1654A43643FE|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14191	uniprotkb:P43351	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706506	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	intact-crc:D46DB7A22FC78BE7|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P43351	uniprotkb:Q14191	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706513	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	intact-crc:2C63761C0BAADE5C|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14191	uniprotkb:P43351	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	go:"GO:0005634"(nucleus)	-	-	comment:Proteins are endogenous	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/11/07	2014/10/16	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	intact-crc:19161098B2DC656F|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14191	uniprotkb:P43351	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706533	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	go:"GO:0005634"(nucleus)	-	-	comment:Proteins are endogenous	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/11/07	2014/10/16	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	intact-crc:58B46178BBCB86F1|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P43351	uniprotkb:Q14191	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706549	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)	-	-	comment:Proteins are overexpressed	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/11/07	2014/10/16	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	intact-crc:155E8A51D119D2BD|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	green fluorescent protein tag:n-n	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14191	uniprotkb:P43351	intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139	intact:EBI-706448|uniprotkb:Q13205|uniprotkb:Q9Y5T7|uniprotkb:Q9Y5T8|uniprotkb:Q9Y5T9|ensembl:ENSP00000351284|ensembl:ENSP00000387901	psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym)	psi-mi:rad52_human(display_long)|uniprotkb:RAD52(gene name)|psi-mi:RAD52(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Baynton et al. (2003)	pubmed:12750383|mint:MINT-5216387	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-706570	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N	refseq:NP_001284348.1|refseq:NP_001284349.1|refseq:NP_602296.2|refseq:XP_005253777.1|refseq:XP_005253778.1|refseq:XP_011519292.1|refseq:XP_011519293.1|refseq:XP_016875258.1|dip:DIP-333N|ensembl:ENSG00000002016(gene)|ensembl:ENST00000358495(transcript)|ensembl:ENST00000430095(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045002"(double-strand break repair via single-strand annealing)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR004585(Recombination protein Rad52)|interpro:IPR007232(Rad52/22 double-strand break repair protein)|interpro:IPR041247|interpro:IPR042525|rcsb pdb:1H2I|rcsb pdb:1KN0|rcsb pdb:5JRB|rcsb pdb:5XRZ|rcsb pdb:5XS0|reactome:R-HSA-3108214|reactome:R-HSA-5685938	go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)	-	-	comment:Proteins are overexpressed|stimulant:Treatment of mitomycin C enhanced the co-localization of RAD52 and WRN in nuclear foci|comment:RAD52 and WRN co-localize in response to DNA damage to nuclear foci corresponding to arrested replication forks	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/11/07	2014/10/16	rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606	rogid:JrWGWVeg6vTeHBSB7gMSWdHR0MM9606	intact-crc:A7D5591AE6E62918|rigid:v1RyilLvZz9vtZjfh/6cj429qFE	false	green fluorescent protein tag:n-n	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)