#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P19429	uniprotkb:Q59H18	intact:EBI-704146|ensembl:ENSP00000341838	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	psi-mi:tnni3_human(display_long)|uniprotkb:Cardiac troponin I(gene name synonym)|uniprotkb:TNNI3(gene name)|psi-mi:TNNI3(display_short)|uniprotkb:TNNC1(gene name synonym)	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000354.4|dip:DIP-34065N|ensembl:ENSG00000129991(gene)|ensembl:ENST00000344887(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001980"(regulation of systemic arterial blood pressure by ischemic conditions)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005861"(troponin complex)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006936"(muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030172"(troponin C binding)|go:"GO:0031014"(troponin T binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|interpro:IPR021666|interpro:IPR038077|mint:P19429|rcsb pdb:1J1D|rcsb pdb:1J1E|rcsb pdb:1LXF|rcsb pdb:1MXL|rcsb pdb:1OZS|rcsb pdb:2KGB|rcsb pdb:2KRD|rcsb pdb:2L1R|rcsb pdb:2MZP|rcsb pdb:2N7L|rcsb pdb:4Y99|rcsb pdb:5VLN|rcsb pdb:5W88|rcsb pdb:5WCL|rcsb pdb:6KN7|rcsb pdb:6KN8|rcsb pdb:6MV3|rcsb pdb:7JGI|reactome:R-HSA-390522|reactome:R-HSA-5578775	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/02	2014/10/16	rogid:kLAHLvln+lIzJRQ8Dit1sSKw/6Y9606	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	intact-crc:56CBA35D33471B28|rigid:Ye4rHGh4k0Td2uT7hxRcxsgJXXs	false	-	binding-associated region:632-734	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q59H18	uniprotkb:P68032	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/02	2014/10/16	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606	intact-crc:E0B51B44E6D7AF96|rigid:bCcX+75sHO4CYkZBhYBb04rWh3I	false	binding-associated region:632-734	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68133	uniprotkb:Q59H18	intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704170	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/02	2014/10/16	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	intact-crc:6BFFF4C7C9B5746C|rigid:bfwF9J+DmVqalimmgntDu/7hTy8	false	-	binding-associated region:632-734	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14896	uniprotkb:Q59H18	intact:EBI-704176|uniprotkb:Q16410|uniprotkb:Q6R2F7|uniprotkb:Q9UE27|uniprotkb:A5PL00|uniprotkb:Q9UM53|ensembl:ENSP00000442795	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	psi-mi:mypc3_human(display_long)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)|uniprotkb:MYBPC3(gene name)|psi-mi:MYBPC3(display_short)	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000247.2|ensembl:ENSG00000134571(gene)|ensembl:ENST00000545968(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014705"(C zone)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031432"(titin binding)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032971"(regulation of muscle filament sliding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q14896|rcsb pdb:1GXE|rcsb pdb:1PD6|rcsb pdb:2AVG|rcsb pdb:2K1M|rcsb pdb:2MQ0|rcsb pdb:2MQ3|rcsb pdb:2V6H|rcsb pdb:3CX2|rcsb pdb:5K6P|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|reactome:R-HSA-390522	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/02	2014/10/16	rogid:JYH9WxTpibBvj4Z6y0ZNgQEW2zE9606	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	intact-crc:BF7D8F17076E581A|rigid:8d0eHqVBT5fDx+EkWFQ3OzMAVKM	false	-	binding-associated region:632-734	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00170	uniprotkb:Q59H18	intact:EBI-704197|uniprotkb:Q2M3Q2|uniprotkb:Q99606|uniprotkb:A0SZW3|uniprotkb:A0SZW4|uniprotkb:A0SZW5|uniprotkb:A0SZW6|ensembl:ENSP00000279146	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	psi-mi:aip_human(display_long)|uniprotkb:Aryl-hydrocarbon receptor-interacting protein(gene name synonym)|uniprotkb:Immunophilin homolog ARA9(gene name synonym)|uniprotkb:HBV X-associated protein 2(gene name synonym)|uniprotkb:AIP(gene name)|psi-mi:AIP(display_short)|uniprotkb:XAP2(gene name synonym)	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704210	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003968.3|refseq:NP_001289888.1|refseq:NP_001289889.1|dip:DIP-34068N|ensembl:ENSG00000110711(gene)|ensembl:ENST00000279146(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0036004"(GAF domain binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031208|interpro:IPR039663|mint:O00170|rcsb pdb:2LKN|rcsb pdb:4AIF|rcsb pdb:4APO|reactome:R-HSA-8937144|reactome:R-HSA-8950505	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/02	2014/10/16	rogid:uCcvOG+bNnmT2zzm58nXhAzKbWo9606	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	intact-crc:F5A1572322770DB5|rigid:YqgrErZh55LMPGhjf0axgqW2R8A	false	-	binding-associated region:632-734	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q59H18	uniprotkb:P05413	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	intact:EBI-704216|uniprotkb:Q5VV93|uniprotkb:Q99957|uniprotkb:B2RAB6|ensembl:ENSP00000362817	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	psi-mi:fabph_human(display_long)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Muscle fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)|uniprotkb:FABP3(gene name)|psi-mi:FABP3(display_short)|uniprotkb:FABP11(gene name synonym)|uniprotkb:MDGI(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	refseq:NP_004093.1|ensembl:ENSG00000121769(gene)|ensembl:ENST00000373713(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P05413|rcsb pdb:1G5W|rcsb pdb:1HMR|rcsb pdb:1HMS|rcsb pdb:1HMT|rcsb pdb:2HMB|rcsb pdb:3RSW|rcsb pdb:3WBG|rcsb pdb:3WVM|rcsb pdb:3WXQ|rcsb pdb:4TJZ|rcsb pdb:4TKB|rcsb pdb:4TKH|rcsb pdb:4TKJ|rcsb pdb:4WBK|rcsb pdb:5B27|rcsb pdb:5B28|rcsb pdb:5B29|rcsb pdb:5CE4|rcsb pdb:5HZ9|rcsb pdb:6AQ1|reactome:R-HSA-163560	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/02	2014/10/16	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	rogid:19jy5yMjaN9ICcn2IR6NtqyZGuA9606	intact-crc:1D7C42F565C578A1|rigid:7JNnM3hICFZbS2uPcy4A56ne9v8	false	binding-associated region:632-734	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q59H18	uniprotkb:P55084	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/02	2014/10/16	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	intact-crc:699FFBFDF2D87458|rigid:1yDxNKZc2Ts+S8NF/hm7PsS3uSQ	false	binding-associated region:632-734	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19429	uniprotkb:Q59H18	intact:EBI-704146|ensembl:ENSP00000341838	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	psi-mi:tnni3_human(display_long)|uniprotkb:Cardiac troponin I(gene name synonym)|uniprotkb:TNNI3(gene name)|psi-mi:TNNI3(display_short)|uniprotkb:TNNC1(gene name synonym)	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000354.4|dip:DIP-34065N|ensembl:ENSG00000129991(gene)|ensembl:ENST00000344887(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001980"(regulation of systemic arterial blood pressure by ischemic conditions)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005861"(troponin complex)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006936"(muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030172"(troponin C binding)|go:"GO:0031014"(troponin T binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|interpro:IPR021666|interpro:IPR038077|mint:P19429|rcsb pdb:1J1D|rcsb pdb:1J1E|rcsb pdb:1LXF|rcsb pdb:1MXL|rcsb pdb:1OZS|rcsb pdb:2KGB|rcsb pdb:2KRD|rcsb pdb:2L1R|rcsb pdb:2MZP|rcsb pdb:2N7L|rcsb pdb:4Y99|rcsb pdb:5VLN|rcsb pdb:5W88|rcsb pdb:5WCL|rcsb pdb:6KN7|rcsb pdb:6KN8|rcsb pdb:6MV3|rcsb pdb:7JGI|reactome:R-HSA-390522|reactome:R-HSA-5578775	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	-	-	-	dataset:Cardiac - Interactions involving cardiac related proteins	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/11/02	2014/10/16	rogid:kLAHLvln+lIzJRQ8Dit1sSKw/6Y9606	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	intact-crc:A5F297057D317B78|rigid:Ye4rHGh4k0Td2uT7hxRcxsgJXXs	false	flag tag:?-?	tag:?-?	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q59H18	-	intact:EBI-704142|uniprotkb:Q17RN0|uniprotkb:Q49AR1|uniprotkb:Q6MZS9|uniprotkb:Q9Y2V6|ensembl:ENSP00000322251	-	psi-mi:tni3k_human(display_long)|uniprotkb:TNNI3-interacting kinase(gene name synonym)|uniprotkb:Cardiac ankyrin repeat kinase(gene name synonym)|uniprotkb:Cardiac troponin I-interacting kinase(gene name synonym)|uniprotkb:TNNI3K(gene name)|psi-mi:TNNI3K(display_short)|uniprotkb:CARK(gene name synonym)	-	psi-mi:"MI:0424"(protein kinase assay)	Zhao et al. (2003)	pubmed:12721663	taxid:9606(human)|taxid:9606(Homo sapiens)	-	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-704259	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	refseq:NP_057062.1|refseq:NP_001186256.2|ensembl:ENSG00000116783(gene)|ensembl:ENST00000326637(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031013"(troponin I binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0086069"(bundle of His cell to Purkinje myocyte communication)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020683|interpro:IPR036770|rcsb pdb:4YFF|rcsb pdb:4YFI|rcsb pdb:6B5J	-	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	resulting-ptm:Autophosphorylation of TNNI3K|dataset:Cardiac - Interactions involving cardiac related proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/02	2014/10/16	rogid:trOxI9wDWShTjC1604gnxBLg+Vo9606	-	intact-crc:F8DAF99ACF8D0E21	false	his tag:?-?|mutation decreasing interaction:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	-