#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9QZE2	uniprotkb:O35601	intact:EBI-8040679|uniprotkb:Q8C479|uniprotkb:Q9JMJ3|intact:MINT-263696|ensembl:ENSMUSP00000128473	intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947	psi-mi:clnk_mouse(display_long)|uniprotkb:Mast cell immunoreceptor signal transducer(gene name synonym)|uniprotkb:Clnk(gene name)|psi-mi:Clnk(display_short)|uniprotkb:Mist(gene name synonym)	psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631074|mint:MINT-58741	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011239036.1|refseq:NP_038776.3|refseq:XP_006504037.1|ensembl:ENSMUSG00000039315(gene)|ensembl:ENSMUST00000169819(transcript)|go:"GO:0002729"(positive regulation of natural killer cell cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010941"(regulation of cell death)|go:"GO:0032815"(negative regulation of natural killer cell activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042629"(mast cell granule)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|mint:Q9QZE2|mint:MINT-732383(identity)	refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-732389(identity)	-	function:"Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT"|comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:BIOSOURCE= RBL-2H3 rat cells|comment:homomint|comment:mint	taxid:10116(rat-rbl_2h3)|taxid:10116(Rat basophilic leukemia cell line)	-	2005/06/22	2014/10/16	rogid:38yghnd92MMW2BTGaThW9cRqyeg10090	rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090	intact-crc:2F2811764883152A|rigid:iFYa+Hm3HeLJe5wfaJzYJHNlkBo	false	tag:?-?(MINT-732384)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0093"(protein sequence identification)
uniprotkb:Q9QZE2	uniprotkb:P25911	intact:EBI-8040679|uniprotkb:Q8C479|uniprotkb:Q9JMJ3|intact:MINT-263696|ensembl:ENSMUSP00000128473	intact:EBI-643537|uniprotkb:Q62127|ensembl:ENSMUSP00000038838	psi-mi:clnk_mouse(display_long)|uniprotkb:Mast cell immunoreceptor signal transducer(gene name synonym)|uniprotkb:Clnk(gene name)|psi-mi:Clnk(display_short)|uniprotkb:Mist(gene name synonym)	psi-mi:lyn_mouse(display_long)|uniprotkb:Lyn(gene name)|psi-mi:Lyn(display_short)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631097|mint:MINT-58742	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011239036.1|refseq:NP_038776.3|refseq:XP_006504037.1|ensembl:ENSMUSG00000039315(gene)|ensembl:ENSMUST00000169819(transcript)|go:"GO:0002729"(positive regulation of natural killer cell cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010941"(regulation of cell death)|go:"GO:0032815"(negative regulation of natural killer cell activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042629"(mast cell granule)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|mint:Q9QZE2|mint:MINT-732546(identity)	refseq:NP_001104566.1|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043200"(response to amino acid)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|ensembl:ENSMUSG00000042228(gene)|ensembl:ENSMUST00000041377(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0002576"(platelet degranulation)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0002768"(immune response-regulating cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0002902"(regulation of B cell apoptotic process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005128"(erythropoietin receptor binding)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006991"(response to sterol depletion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009725"(response to hormone)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0070304"(positive regulation of stress-activated protein kinase signaling cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070667"(negative regulation of mast cell proliferation)|go:"GO:0070668"(positive regulation of mast cell proliferation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090025"(regulation of monocyte chemotaxis)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1902532"(negative regulation of intracellular signal transduction)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050855"(regulation of B cell receptor signaling pathway)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060369"(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|reactome:R-MMU-2871837|reactome:R-MMU-389356|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928665|reactome:R-MMU-5621480|reactome:R-MMU-5621575|reactome:R-MMU-5690714|reactome:R-MMU-69231|reactome:R-MMU-75892|reactome:R-MMU-9027276|reactome:R-MMU-9027284|reactome:R-MMU-912631|reactome:R-MMU-9674555|reactome:R-MMU-9705462|reactome:R-MMU-982772|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035748|interpro:IPR035852|interpro:IPR036028|interpro:IPR036860|mint:P25911|rcsb pdb:2ZV7|rcsb pdb:2ZV8|rcsb pdb:2ZV9|rcsb pdb:2ZVA|rcsb pdb:4TZI|reactome:R-MMU-114604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202733|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-2454202|reactome:R-MMU-2730905|interpro:IPR020635|reactome:R-MMU-2871796|reactome:R-MMU-2871809|dip:DIP-37806N|mint:MINT-732555(identity)	-	function:"Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:The interaction occurs in cells coexpressing SKAP55 and SLAP-130|comment:homomint|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/06/22	2014/10/16	rogid:38yghnd92MMW2BTGaThW9cRqyeg10090	rogid:LjzRpfHDK7fzcRGOrdNV3LH/N2U10090	intact-crc:1667BBCC95459441|rigid:ApNX2MaIL09DlBwzubqYAwJreb0	false	tag:?-?(MINT-732550)|binding-associated region:309-392(MINT-732547)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9QZE2	uniprotkb:Q3UND0	intact:EBI-8040679|uniprotkb:Q8C479|uniprotkb:Q9JMJ3|intact:MINT-263696|ensembl:ENSMUSP00000128473	intact:EBI-642769|uniprotkb:Q8BK74|uniprotkb:Q9Z2K4|ensembl:ENSMUSP00000145462	psi-mi:clnk_mouse(display_long)|uniprotkb:Mast cell immunoreceptor signal transducer(gene name synonym)|uniprotkb:Clnk(gene name)|psi-mi:Clnk(display_short)|uniprotkb:Mist(gene name synonym)	psi-mi:skap2_mouse(display_long)|uniprotkb:Src family-associated phosphoprotein 2(gene name synonym)|uniprotkb:Src kinase-associated phosphoprotein 55-related protein(gene name synonym)|uniprotkb:SKAP55 homolog(gene name synonym)|uniprotkb:Src-associated adapter protein with PH and SH3 domains(gene name synonym)|uniprotkb:Pyk2/RAFTK-associated protein(gene name synonym)|uniprotkb:Skap2(gene name)|psi-mi:Skap2(display_short)|uniprotkb:Prap(gene name synonym)|uniprotkb:Saps(gene name synonym)|uniprotkb:Ra70(gene name synonym)|uniprotkb:Scap2(gene name synonym)|uniprotkb:Skap55r(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631116|mint:MINT-58743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011239036.1|refseq:NP_038776.3|refseq:XP_006504037.1|ensembl:ENSMUSG00000039315(gene)|ensembl:ENSMUST00000169819(transcript)|go:"GO:0002729"(positive regulation of natural killer cell cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010941"(regulation of cell death)|go:"GO:0032815"(negative regulation of natural killer cell activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042629"(mast cell granule)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|mint:Q9QZE2|mint:MINT-732399(identity)	refseq:NP_061243.1|ensembl:ENSMUSG00000059182(gene)|ensembl:ENSMUST00000204778(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042113"(B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|interpro:IPR037781|rcsb pdb:1M0V|rcsb pdb:1U5E|rcsb pdb:1U5F|rcsb pdb:1U5G|rcsb pdb:2OTX|reactome:R-MMU-391160|mint:MINT-732408(identity)	-	function:"Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:Interaction occurs in presence of SLAP-130|comment:homomint|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/06/22	2014/10/16	rogid:38yghnd92MMW2BTGaThW9cRqyeg10090	rogid:2WPz/JocPjHR9w8dHv5ha396QWQ10090	intact-crc:D11914BB2406D76C|rigid:A+5baPX2Fc6FcSge/QqgFLk3PWc	false	tag:?-?(MINT-732403)|binding-associated region:309-392(MINT-732400)	tag:?-?(MINT-732409)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9QZE2	uniprotkb:P39688	intact:EBI-8040679|uniprotkb:Q8C479|uniprotkb:Q9JMJ3|intact:MINT-263696|ensembl:ENSMUSP00000128473	intact:EBI-524514|uniprotkb:Q3TAT3|uniprotkb:Q3U0T5|uniprotkb:Q8K2A3|ensembl:ENSMUSP00000097547	psi-mi:clnk_mouse(display_long)|uniprotkb:Mast cell immunoreceptor signal transducer(gene name synonym)|uniprotkb:Clnk(gene name)|psi-mi:Clnk(display_short)|uniprotkb:Mist(gene name synonym)	psi-mi:fyn_mouse(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Fyn(gene name)|psi-mi:Fyn(display_short)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631173|mint:MINT-58745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011239036.1|refseq:NP_038776.3|refseq:XP_006504037.1|ensembl:ENSMUSG00000039315(gene)|ensembl:ENSMUST00000169819(transcript)|go:"GO:0002729"(positive regulation of natural killer cell cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010941"(regulation of cell death)|go:"GO:0032815"(negative regulation of natural killer cell activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042629"(mast cell granule)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|mint:Q9QZE2|mint:MINT-732420(identity)	ensembl:ENSMUSG00000019843(gene)|ensembl:ENSMUST00000099967(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001764"(neuron migration)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003015"(heart process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042552"(myelination)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0015631"(tubulin binding)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0014069"(postsynaptic density)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR036028|mint:P39688|rcsb pdb:3UF4|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1227986|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202733|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-373753|reactome:R-MMU-375165|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-5621480|reactome:R-MMU-5621575|reactome:R-MMU-5673001|reactome:R-MMU-6811558|reactome:R-MMU-75892|reactome:R-MMU-8866376|reactome:R-MMU-9032759|reactome:R-MMU-912631|refseq:NP_001116364.1|refseq:NP_001116365.1|refseq:NP_032080.2|refseq:XP_006512602.1|refseq:XP_006512603.1|refseq:XP_011241419.1|dip:DIP-198N|mint:MINT-732424(identity)	-	function:"Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5A|comment:BIOSOURCE= MC/9 mouse cells|comment:homomint|comment:mint	taxid:10090(mouse-mc/9)|taxid:10090(Mus musculus)	-	2005/06/22	2014/10/16	rogid:38yghnd92MMW2BTGaThW9cRqyeg10090	rogid:QVU98HrNOdxdJIzSvFWdhZ914MQ10090	intact-crc:DDAF4FFD2534FE13|rigid:+6ji0jZmMDu/GGcygNQKAppQcNg	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P06240	uniprotkb:Q3UND0	intact:EBI-1401|ensembl:ENSMUSP00000066209|ensembl:ENSMUSP00000099656|uniprotkb:Q62320|uniprotkb:Q61795|uniprotkb:Q61794|uniprotkb:Q91X65	intact:EBI-642769|uniprotkb:Q8BK74|uniprotkb:Q9Z2K4|ensembl:ENSMUSP00000145462	psi-mi:lck_mouse(display_long)|uniprotkb:Lck(gene name)|psi-mi:Lck(display_short)|uniprotkb:Lsk-t(gene name synonym)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:skap2_mouse(display_long)|uniprotkb:Src family-associated phosphoprotein 2(gene name synonym)|uniprotkb:Src kinase-associated phosphoprotein 55-related protein(gene name synonym)|uniprotkb:SKAP55 homolog(gene name synonym)|uniprotkb:Src-associated adapter protein with PH and SH3 domains(gene name synonym)|uniprotkb:Pyk2/RAFTK-associated protein(gene name synonym)|uniprotkb:Skap2(gene name)|psi-mi:Skap2(display_short)|uniprotkb:Prap(gene name synonym)|uniprotkb:Saps(gene name synonym)|uniprotkb:Ra70(gene name synonym)|uniprotkb:Scap2(gene name synonym)|uniprotkb:Skap55r(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631208|mint:MINT-58746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000409(gene)|ensembl:ENSMUST00000067240(transcript)|ensembl:ENSMUST00000102596(transcript)|go:"GO:0000242"(pericentriolar material)|refseq:NP_001155905.1|refseq:NP_034823.1|refseq:XP_006502881.1|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003823"(antigen binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010038"(response to metal ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070474"(positive regulation of uterine smooth muscle contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-6811558|reactome:R-MMU-9013407|reactome:R-MMU-9020558|reactome:R-MMU-9706374|mint:MINT-732514(identity)	refseq:NP_061243.1|ensembl:ENSMUSG00000059182(gene)|ensembl:ENSMUST00000204778(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042113"(B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|interpro:IPR037781|rcsb pdb:1M0V|rcsb pdb:1U5E|rcsb pdb:1U5F|rcsb pdb:1U5G|rcsb pdb:2OTX|reactome:R-MMU-391160|mint:MINT-732523(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/22	2014/10/16	rogid:yjMU0fxTseBSR5/aEXmp2cR7Mts10090	rogid:2WPz/JocPjHR9w8dHv5ha396QWQ10090	intact-crc:FB8D58728CF52B20|rigid:/yC6cPG5sgY1CzMB3D7OzzyuxGY	false	tag:?-?(MINT-732518)|binding-associated region:126-208(MINT-732515)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35601	uniprotkb:P39688	intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947	intact:EBI-524514|uniprotkb:Q3TAT3|uniprotkb:Q3U0T5|uniprotkb:Q8K2A3|ensembl:ENSMUSP00000097547	psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym)	psi-mi:fyn_mouse(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Fyn(gene name)|psi-mi:Fyn(display_short)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631286|mint:MINT-58748	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-732491(identity)	ensembl:ENSMUSG00000019843(gene)|ensembl:ENSMUST00000099967(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001764"(neuron migration)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003015"(heart process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042552"(myelination)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0015631"(tubulin binding)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0014069"(postsynaptic density)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR036028|mint:P39688|rcsb pdb:3UF4|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1227986|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202733|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-373753|reactome:R-MMU-375165|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-5621480|reactome:R-MMU-5621575|reactome:R-MMU-5673001|reactome:R-MMU-6811558|reactome:R-MMU-75892|reactome:R-MMU-8866376|reactome:R-MMU-9032759|reactome:R-MMU-912631|refseq:NP_001116364.1|refseq:NP_001116365.1|refseq:NP_032080.2|refseq:XP_006512602.1|refseq:XP_006512603.1|refseq:XP_011241419.1|dip:DIP-198N|mint:MINT-732482(identity)	-	comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/22	2014/10/16	rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090	rogid:QVU98HrNOdxdJIzSvFWdhZ914MQ10090	intact-crc:1D6A8D573F34BE15|rigid:ykgQJrNyDAYlh36U6JmRBFm00N4	false	-	binding-associated region:?-?(MINT-732483)|tag:?-?(MINT-732486)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35601	uniprotkb:P06240	intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947	intact:EBI-1401|ensembl:ENSMUSP00000066209|ensembl:ENSMUSP00000099656|uniprotkb:Q62320|uniprotkb:Q61795|uniprotkb:Q61794|uniprotkb:Q91X65	psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym)	psi-mi:lck_mouse(display_long)|uniprotkb:Lck(gene name)|psi-mi:Lck(display_short)|uniprotkb:Lsk-t(gene name synonym)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631247|mint:MINT-58747	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-732507(identity)	ensembl:ENSMUSG00000000409(gene)|ensembl:ENSMUST00000067240(transcript)|ensembl:ENSMUST00000102596(transcript)|go:"GO:0000242"(pericentriolar material)|refseq:NP_001155905.1|refseq:NP_034823.1|refseq:XP_006502881.1|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003823"(antigen binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010038"(response to metal ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070474"(positive regulation of uterine smooth muscle contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-6811558|reactome:R-MMU-9013407|reactome:R-MMU-9020558|reactome:R-MMU-9706374|mint:MINT-732498(identity)	-	comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/22	2014/10/16	rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090	rogid:yjMU0fxTseBSR5/aEXmp2cR7Mts10090	intact-crc:5990BE1D3C0CA166|rigid:Hbd+ZguNPWY4EzTVvx5t+c1XJF4	false	-	binding-associated region:126-208(MINT-732499)|tag:?-?(MINT-732502)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q3UND0	uniprotkb:P25911	intact:EBI-642769|uniprotkb:Q8BK74|uniprotkb:Q9Z2K4|ensembl:ENSMUSP00000145462	intact:EBI-643537|uniprotkb:Q62127|ensembl:ENSMUSP00000038838	psi-mi:skap2_mouse(display_long)|uniprotkb:Src family-associated phosphoprotein 2(gene name synonym)|uniprotkb:Src kinase-associated phosphoprotein 55-related protein(gene name synonym)|uniprotkb:SKAP55 homolog(gene name synonym)|uniprotkb:Src-associated adapter protein with PH and SH3 domains(gene name synonym)|uniprotkb:Pyk2/RAFTK-associated protein(gene name synonym)|uniprotkb:Skap2(gene name)|psi-mi:Skap2(display_short)|uniprotkb:Prap(gene name synonym)|uniprotkb:Saps(gene name synonym)|uniprotkb:Ra70(gene name synonym)|uniprotkb:Scap2(gene name synonym)|uniprotkb:Skap55r(gene name synonym)	psi-mi:lyn_mouse(display_long)|uniprotkb:Lyn(gene name)|psi-mi:Lyn(display_short)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631358|mint:MINT-58750	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061243.1|ensembl:ENSMUSG00000059182(gene)|ensembl:ENSMUST00000204778(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042113"(B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|interpro:IPR037781|rcsb pdb:1M0V|rcsb pdb:1U5E|rcsb pdb:1U5F|rcsb pdb:1U5G|rcsb pdb:2OTX|reactome:R-MMU-391160|mint:MINT-732443(identity)	refseq:NP_001104566.1|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043200"(response to amino acid)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|ensembl:ENSMUSG00000042228(gene)|ensembl:ENSMUST00000041377(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0002576"(platelet degranulation)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0002768"(immune response-regulating cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0002902"(regulation of B cell apoptotic process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005128"(erythropoietin receptor binding)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006991"(response to sterol depletion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009725"(response to hormone)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0070304"(positive regulation of stress-activated protein kinase signaling cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070667"(negative regulation of mast cell proliferation)|go:"GO:0070668"(positive regulation of mast cell proliferation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090025"(regulation of monocyte chemotaxis)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1902532"(negative regulation of intracellular signal transduction)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050855"(regulation of B cell receptor signaling pathway)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060369"(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|reactome:R-MMU-2871837|reactome:R-MMU-389356|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928665|reactome:R-MMU-5621480|reactome:R-MMU-5621575|reactome:R-MMU-5690714|reactome:R-MMU-69231|reactome:R-MMU-75892|reactome:R-MMU-9027276|reactome:R-MMU-9027284|reactome:R-MMU-912631|reactome:R-MMU-9674555|reactome:R-MMU-9705462|reactome:R-MMU-982772|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035748|interpro:IPR035852|interpro:IPR036028|interpro:IPR036860|mint:P25911|rcsb pdb:2ZV7|rcsb pdb:2ZV8|rcsb pdb:2ZV9|rcsb pdb:2ZVA|rcsb pdb:4TZI|reactome:R-MMU-114604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202733|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-2454202|reactome:R-MMU-2730905|interpro:IPR020635|reactome:R-MMU-2871796|reactome:R-MMU-2871809|dip:DIP-37806N|mint:MINT-732434(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/22	2014/10/16	rogid:2WPz/JocPjHR9w8dHv5ha396QWQ10090	rogid:LjzRpfHDK7fzcRGOrdNV3LH/N2U10090	intact-crc:E9E7ED3844CACAD5|rigid:n8FOn7ZjtQUcjyPuYJrllKwA+c0	false	-	binding-associated region:128-210(MINT-732435)|tag:?-?(MINT-732438)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q3UND0	uniprotkb:P39688	intact:EBI-642769|uniprotkb:Q8BK74|uniprotkb:Q9Z2K4|ensembl:ENSMUSP00000145462	intact:EBI-524514|uniprotkb:Q3TAT3|uniprotkb:Q3U0T5|uniprotkb:Q8K2A3|ensembl:ENSMUSP00000097547	psi-mi:skap2_mouse(display_long)|uniprotkb:Src family-associated phosphoprotein 2(gene name synonym)|uniprotkb:Src kinase-associated phosphoprotein 55-related protein(gene name synonym)|uniprotkb:SKAP55 homolog(gene name synonym)|uniprotkb:Src-associated adapter protein with PH and SH3 domains(gene name synonym)|uniprotkb:Pyk2/RAFTK-associated protein(gene name synonym)|uniprotkb:Skap2(gene name)|psi-mi:Skap2(display_short)|uniprotkb:Prap(gene name synonym)|uniprotkb:Saps(gene name synonym)|uniprotkb:Ra70(gene name synonym)|uniprotkb:Scap2(gene name synonym)|uniprotkb:Skap55r(gene name synonym)	psi-mi:fyn_mouse(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Fyn(gene name)|psi-mi:Fyn(display_short)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631337|mint:MINT-58749	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061243.1|ensembl:ENSMUSG00000059182(gene)|ensembl:ENSMUST00000204778(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042113"(B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|interpro:IPR037781|rcsb pdb:1M0V|rcsb pdb:1U5E|rcsb pdb:1U5F|rcsb pdb:1U5G|rcsb pdb:2OTX|reactome:R-MMU-391160|mint:MINT-732459(identity)	ensembl:ENSMUSG00000019843(gene)|ensembl:ENSMUST00000099967(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001764"(neuron migration)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003015"(heart process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042552"(myelination)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0015631"(tubulin binding)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0014069"(postsynaptic density)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR036028|mint:P39688|rcsb pdb:3UF4|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1227986|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202733|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-373753|reactome:R-MMU-375165|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-5621480|reactome:R-MMU-5621575|reactome:R-MMU-5673001|reactome:R-MMU-6811558|reactome:R-MMU-75892|reactome:R-MMU-8866376|reactome:R-MMU-9032759|reactome:R-MMU-912631|refseq:NP_001116364.1|refseq:NP_001116365.1|refseq:NP_032080.2|refseq:XP_006512602.1|refseq:XP_006512603.1|refseq:XP_011241419.1|dip:DIP-198N|mint:MINT-732450(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/22	2014/10/16	rogid:2WPz/JocPjHR9w8dHv5ha396QWQ10090	rogid:QVU98HrNOdxdJIzSvFWdhZ914MQ10090	intact-crc:888ED88EB992E5DD|rigid:7RcCJz9S7wlMWs/GhGJLZjmB+iY	false	-	binding-associated region:?-?(MINT-732451)|tag:?-?(MINT-732454)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35601	uniprotkb:P25911	intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947	intact:EBI-643537|uniprotkb:Q62127|ensembl:ENSMUSP00000038838	psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym)	psi-mi:lyn_mouse(display_long)|uniprotkb:Lyn(gene name)|psi-mi:Lyn(display_short)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631376|mint:MINT-58751	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-732475(identity)	refseq:NP_001104566.1|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043200"(response to amino acid)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|ensembl:ENSMUSG00000042228(gene)|ensembl:ENSMUST00000041377(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0002513"(tolerance induction to self antigen)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0002576"(platelet degranulation)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0002768"(immune response-regulating cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0002902"(regulation of B cell apoptotic process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005128"(erythropoietin receptor binding)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006991"(response to sterol depletion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009725"(response to hormone)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0070304"(positive regulation of stress-activated protein kinase signaling cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070667"(negative regulation of mast cell proliferation)|go:"GO:0070668"(positive regulation of mast cell proliferation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090025"(regulation of monocyte chemotaxis)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1902532"(negative regulation of intracellular signal transduction)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050855"(regulation of B cell receptor signaling pathway)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060369"(positive regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0043407"(negative regulation of MAP kinase activity)|reactome:R-MMU-2871837|reactome:R-MMU-389356|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928665|reactome:R-MMU-5621480|reactome:R-MMU-5621575|reactome:R-MMU-5690714|reactome:R-MMU-69231|reactome:R-MMU-75892|reactome:R-MMU-9027276|reactome:R-MMU-9027284|reactome:R-MMU-912631|reactome:R-MMU-9674555|reactome:R-MMU-9705462|reactome:R-MMU-982772|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035748|interpro:IPR035852|interpro:IPR036028|interpro:IPR036860|mint:P25911|rcsb pdb:2ZV7|rcsb pdb:2ZV8|rcsb pdb:2ZV9|rcsb pdb:2ZVA|rcsb pdb:4TZI|reactome:R-MMU-114604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202733|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-2454202|reactome:R-MMU-2730905|interpro:IPR020635|reactome:R-MMU-2871796|reactome:R-MMU-2871809|dip:DIP-37806N|mint:MINT-732466(identity)	-	comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/22	2014/10/16	rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090	rogid:LjzRpfHDK7fzcRGOrdNV3LH/N2U10090	intact-crc:31FE38CFF41E51BB|rigid:JhuZl/iEce9batBtasLGT4yMbWk	false	-	tag:?-?(MINT-732470)|binding-associated region:128-210(MINT-732467)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9QZE2	uniprotkb:Q4V7G1	intact:EBI-8040679|uniprotkb:Q8C479|uniprotkb:Q9JMJ3|intact:MINT-263696|ensembl:ENSMUSP00000128473	intact:EBI-8631431|ensembl:ENSRNOP00000033594|uniprotkb:Q8CHI6|intact:MINT-263796	psi-mi:clnk_mouse(display_long)|uniprotkb:Mast cell immunoreceptor signal transducer(gene name synonym)|uniprotkb:Clnk(gene name)|psi-mi:Clnk(display_short)|uniprotkb:Mist(gene name synonym)	psi-mi:skap1_rat(display_long)|uniprotkb:Skap1(gene name)|psi-mi:Skap1(display_short)|uniprotkb:Scap1(gene name synonym)|uniprotkb:Skap55(gene name synonym)|uniprotkb:Src family-associated phosphoprotein 1(gene name synonym)|uniprotkb:Src kinase-associated phosphoprotein of 55 kDa(gene name synonym)|uniprotkb:SKAP55 adapter protein(gene name synonym)|uniprotkb:pp55(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631459|mint:MINT-58740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011239036.1|refseq:NP_038776.3|refseq:XP_006504037.1|ensembl:ENSMUSG00000039315(gene)|ensembl:ENSMUST00000169819(transcript)|go:"GO:0002729"(positive regulation of natural killer cell cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010941"(regulation of cell death)|go:"GO:0032815"(negative regulation of natural killer cell activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042629"(mast cell granule)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|mint:Q9QZE2|mint:MINT-732532(identity)	ensembl:ENSRNOG00000023881(gene)|ensembl:ENSRNOT00000030159(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035765|interpro:IPR036028|interpro:IPR037781|rgd:708436|refseq:NP_775433.2|mint:MINT-732538(identity)	-	function:"Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT"|comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:"Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells (By similarity). May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells"|comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:BIOSOURCE= RBL-2H3 rat cells|comment:homomint|comment:mint	taxid:10116(rat-rbl_2h3)|taxid:10116(Rat basophilic leukemia cell line)	-	2005/06/22	2014/10/16	rogid:38yghnd92MMW2BTGaThW9cRqyeg10090	rogid:/XiyOx1YVYonFMjd9D3LPFjWJAg10116	intact-crc:24CED2B548EA0AFF|rigid:bFkMq8LStORFHfWlTa40A0Ae/1k	false	tag:?-?(MINT-732533)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0093"(protein sequence identification)
uniprotkb:O35601	uniprotkb:Q9QZE2	intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947	intact:EBI-8040679|uniprotkb:Q8C479|uniprotkb:Q9JMJ3|intact:MINT-263696|ensembl:ENSMUSP00000128473	psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym)	psi-mi:clnk_mouse(display_long)|uniprotkb:Mast cell immunoreceptor signal transducer(gene name synonym)|uniprotkb:Clnk(gene name)|psi-mi:Clnk(display_short)|uniprotkb:Mist(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujii et al. (2003)	mint:MINT-5216317|pubmed:12681493	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631500|mint:MINT-58744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-732574(identity)	refseq:XP_011239036.1|refseq:NP_038776.3|refseq:XP_006504037.1|ensembl:ENSMUSG00000039315(gene)|ensembl:ENSMUST00000169819(transcript)|go:"GO:0002729"(positive regulation of natural killer cell cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010941"(regulation of cell death)|go:"GO:0032815"(negative regulation of natural killer cell activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042629"(mast cell granule)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|mint:Q9QZE2|mint:MINT-732565(identity)	-	comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0"	function:"Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT"|comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/06/22	2014/10/16	rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090	rogid:38yghnd92MMW2BTGaThW9cRqyeg10090	intact-crc:E38F6F2F47AF43FC|rigid:iFYa+Hm3HeLJe5wfaJzYJHNlkBo	false	tag:?-?(MINT-732575)	binding-associated region:309-392(MINT-732566)|tag:?-?(MINT-732569)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)