#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P41542 uniprotkb:Q6DFZ1 intact:EBI-4423297|ensembl:ENSRNOP00000003277 intact:EBI-761491|ensembl:ENSMUSP00000026254 psi-mi:uso1_rat(display_long)|uniprotkb:Uso1(gene name)|psi-mi:Uso1(display_short)|uniprotkb:Vdp(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym) psi-mi:q6dfz1_mouse(display_long)|uniprotkb:Gbf1(gene name)|psi-mi:Gbf1(display_short) psi-mi:"MI:0018"(two hybrid) Garcia-Mata et al. (2003) pubmed:12634853|imex:IM-23685 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-761498|imex:IM-23685-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621604|refseq:NP_062252.1|ensembl:ENSRNOG00000002301(gene)|ensembl:ENSRNOT00000003277(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0032252"(secretory granule localization)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061025"(membrane fusion)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR041209|reactome:R-RNO-204005|reactome:R-RNO-6807878 refseq:NP_849261.2|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|ensembl:ENSMUSG00000025224(gene)|ensembl:ENSMUST00000026254(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002263"(cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|go:"GO:1903420"(protein localization to endoplasmic reticulum tubular network)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000904(SEC7-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|reactome:R-MMU-199992|reactome:R-MMU-5620916|reactome:R-MMU-6807878|reactome:R-MMU-6811434 - - - comment:20 out of the 40 positive clones in the Y2H screening were identified as GBF1 ORFs.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/11/25 2015/01/15 rogid:lw2vLmxkQMppysDgr/JQoDwzAFE10116 rogid:1Fsgwz3lF1GOnNgsc+MnTyOCOdQ10090 intact-crc:601166D3456BB4AB|rigid:6e0EGsoQRFdc9vpWEIExy3tSWUM false - sufficient binding region:1752-1859 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q921M4 uniprotkb:P41542 intact:EBI-298519|ensembl:ENSMUSP00000109004|uniprotkb:A2AN43|uniprotkb:A2AN47 intact:EBI-4423297|ensembl:ENSRNOP00000003277 psi-mi:goga2_mouse(display_long)|uniprotkb:Golga2(gene name)|psi-mi:Golga2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym) psi-mi:uso1_rat(display_long)|uniprotkb:Uso1(gene name)|psi-mi:Uso1(display_short)|uniprotkb:Vdp(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Garcia-Mata et al. (2003) pubmed:12634853|imex:IM-23685 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-761782|imex:IM-23685-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019905"(syntaxin binding)|refseq:NP_001074437.1|ensembl:ENSMUSG00000002546(gene)|ensembl:ENSMUST00000113377(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051645"(Golgi localization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q921M4|reactome:R-MMU-162658|reactome:R-MMU-204005|reactome:R-MMU-6807878|reactome:R-MMU-9013148|reactome:R-MMU-9013405|refseq:XP_006498556.1 rgd:621604|refseq:NP_062252.1|ensembl:ENSRNOG00000002301(gene)|ensembl:ENSRNOT00000003277(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0032252"(secretory granule localization)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061025"(membrane fusion)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR041209|reactome:R-RNO-204005|reactome:R-RNO-6807878 - - - comment:3 out of the 40 positive clones in the Y2H screening were identified as GM130 ORFs.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/11/25 2015/01/15 rogid:GMrTr2bHQ0lyJ7MV2kNF5+7fhAk10090 rogid:lw2vLmxkQMppysDgr/JQoDwzAFE10116 intact-crc:24F305C0A2E45BA1|rigid:yQo7Kip8yHO7oSb+dTGUG99ki50 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6DFZ1 uniprotkb:P41542 intact:EBI-761491|ensembl:ENSMUSP00000026254 intact:EBI-4423297|ensembl:ENSRNOP00000003277 psi-mi:q6dfz1_mouse(display_long)|uniprotkb:Gbf1(gene name)|psi-mi:Gbf1(display_short) psi-mi:uso1_rat(display_long)|uniprotkb:Uso1(gene name)|psi-mi:Uso1(display_short)|uniprotkb:Vdp(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym) psi-mi:"MI:0096"(pull down) Garcia-Mata et al. (2003) pubmed:12634853|imex:IM-23685 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-761799|imex:IM-23685-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_849261.2|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|ensembl:ENSMUSG00000025224(gene)|ensembl:ENSMUST00000026254(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002263"(cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|go:"GO:1903420"(protein localization to endoplasmic reticulum tubular network)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000904(SEC7-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|reactome:R-MMU-199992|reactome:R-MMU-5620916|reactome:R-MMU-6807878|reactome:R-MMU-6811434 rgd:621604|refseq:NP_062252.1|ensembl:ENSRNOG00000002301(gene)|ensembl:ENSRNOT00000003277(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0032252"(secretory granule localization)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061025"(membrane fusion)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR041209|reactome:R-RNO-204005|reactome:R-RNO-6807878 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/25 2015/01/15 rogid:1Fsgwz3lF1GOnNgsc+MnTyOCOdQ10090 rogid:lw2vLmxkQMppysDgr/JQoDwzAFE10116 intact-crc:110C7B9AD1384024|rigid:6e0EGsoQRFdc9vpWEIExy3tSWUM false sufficient binding region:1752-1859|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1M8X9 uniprotkb:P41542 intact:EBI-779569|ensembl:ENSRNOP00000038037 intact:EBI-4423297|ensembl:ENSRNOP00000003277 psi-mi:f1m8x9_rat(display_long)|uniprotkb:Gbf1(gene name)|psi-mi:Gbf1(display_short) psi-mi:uso1_rat(display_long)|uniprotkb:Uso1(gene name)|psi-mi:Uso1(display_short)|uniprotkb:Vdp(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Garcia-Mata et al. (2003) pubmed:12634853|imex:IM-23685 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-761806|imex:IM-23685-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001178563.1|rgd:1307160|ensembl:ENSRNOG00000026048(gene)|ensembl:ENSRNOT00000036156(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002263"(cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|go:"GO:1903420"(protein localization to endoplasmic reticulum tubular network)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000904(SEC7-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|reactome:R-RNO-199992|reactome:R-RNO-5620916|reactome:R-RNO-6807878|reactome:R-RNO-6811434 rgd:621604|refseq:NP_062252.1|ensembl:ENSRNOG00000002301(gene)|ensembl:ENSRNOT00000003277(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0032252"(secretory granule localization)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061025"(membrane fusion)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR041209|reactome:R-RNO-204005|reactome:R-RNO-6807878 go:"GO:0005829"(cytosol) - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2005/11/25 2015/01/15 rogid:97sidkrN5HpsaswcDk8fAmUeuH410116 rogid:lw2vLmxkQMppysDgr/JQoDwzAFE10116 intact-crc:0CE4C5CF0AA33EAB|rigid:K4nhtzjrE9Ej1fmQfY5hQhcrczQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41542 uniprotkb:Q6DFZ1 intact:EBI-4423297|ensembl:ENSRNOP00000003277 intact:EBI-761491|ensembl:ENSMUSP00000026254 psi-mi:uso1_rat(display_long)|uniprotkb:Uso1(gene name)|psi-mi:Uso1(display_short)|uniprotkb:Vdp(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym) psi-mi:q6dfz1_mouse(display_long)|uniprotkb:Gbf1(gene name)|psi-mi:Gbf1(display_short) psi-mi:"MI:0018"(two hybrid) Garcia-Mata et al. (2003) pubmed:12634853|imex:IM-23685 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-761816|imex:IM-23685-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621604|refseq:NP_062252.1|ensembl:ENSRNOG00000002301(gene)|ensembl:ENSRNOT00000003277(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0032252"(secretory granule localization)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061025"(membrane fusion)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR041209|reactome:R-RNO-204005|reactome:R-RNO-6807878 refseq:NP_849261.2|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|ensembl:ENSMUSG00000025224(gene)|ensembl:ENSMUST00000026254(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002263"(cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|go:"GO:1903420"(protein localization to endoplasmic reticulum tubular network)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000904(SEC7-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|reactome:R-MMU-199992|reactome:R-MMU-5620916|reactome:R-MMU-6807878|reactome:R-MMU-6811434 - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/11/25 2015/01/15 rogid:lw2vLmxkQMppysDgr/JQoDwzAFE10116 rogid:1Fsgwz3lF1GOnNgsc+MnTyOCOdQ10090 intact-crc:2783B43B1AF327C7|rigid:6e0EGsoQRFdc9vpWEIExy3tSWUM false sufficient binding region:1-766|necessary binding region:150-371 sufficient binding region:1752-1859 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60763 uniprotkb:Q92538 intact:EBI-356164|uniprotkb:B2RAQ0|uniprotkb:Q6PK63|uniprotkb:Q8N592|uniprotkb:Q86TB8|ensembl:ENSP00000444850|intact:EBI-21358067 intact:EBI-359050|uniprotkb:Q5VXX3|uniprotkb:Q96CK6|uniprotkb:Q96HZ3|uniprotkb:Q9H473|uniprotkb:Q149P0|uniprotkb:Q149P1|ensembl:ENSP00000503207|ensembl:ENSP00000503981 psi-mi:uso1_human(display_long)|uniprotkb:USO1(gene name)|psi-mi:USO1(display_short)|uniprotkb:VDP(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym) psi-mi:gbf1_human(display_long)|uniprotkb:GBF1(gene name)|psi-mi:GBF1(display_short)|uniprotkb:KIAA0248(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Garcia-Mata et al. (2003) pubmed:12634853|imex:IM-23685 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-761833|imex:IM-23685-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003706.2|refseq:NP_001276978.1|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR041209|mint:O60763|rcsb pdb:2W3C|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|go:"GO:0061025"(membrane fusion)|ensembl:ENSG00000138768(gene)|ensembl:ENST00000514213(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030133"(transport vesicle)|go:"GO:0032252"(secretory granule localization)|go:"GO:0045056"(transcytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm) refseq:NP_001186307.1|refseq:NP_001186308.1|refseq:NP_004184.1|ensembl:ENSP00000503207|ensembl:ENSP00000503981|ensembl:ENST00000676993|ensembl:ENSP00000503918|ensembl:ENST00000677240|ensembl:ENSP00000503428|ensembl:ENSG00000107862(gene)|ensembl:ENST00000676513(transcript)|ensembl:ENST00000676939(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002263"(cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0060271"(cilium assembly)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|go:"GO:1903420"(protein localization to endoplasmic reticulum tubular network)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000904(SEC7-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|mint:Q92538|reactome:R-HSA-199992|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434 go:"GO:0005794"(Golgi apparatus) - - figure legend:Fig. 3B|comment:"GBF1 and p115 colocalizes extensively in the golgi and in periphericalvesicular tubular clusters (VTCs)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/11/25 2015/01/15 rogid:qrBH7A4Ce+01K9Mu8cdVqMYUh4M9606 rogid:4rA/2NVw35m+b6O7/+9noI3EO4o9606 intact-crc:1C30CF0A8A630F0C|rigid:h5B656I2Y5Vd3arGW0CRRKxs6h4 false - myc tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)