#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q495M9 uniprotkb:Q9Y6N9 intact:EBI-8601749|ensembl:ENSP00000480279|uniprotkb:Q8N251|intact:MINT-257481 intact:EBI-954308|ensembl:ENSP00000317018|uniprotkb:Q96B29|uniprotkb:Q9UM04|uniprotkb:Q9UM17|uniprotkb:Q9UPC3|uniprotkb:A8K423|uniprotkb:Q7RTU8 psi-mi:ush1g_human(display_long)|uniprotkb:USH1G(gene name)|psi-mi:USH1G(display_short)|uniprotkb:SANS(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym) psi-mi:ush1c_human(display_long)|uniprotkb:Usher syndrome type-1C protein(gene name synonym)|uniprotkb:Autoimmune enteropathy-related antigen AIE-75(gene name synonym)|uniprotkb:Antigen NY-CO-38/NY-CO-37(gene name synonym)|uniprotkb:Protein PDZ-73(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-3(gene name synonym)|uniprotkb:USH1C(gene name)|psi-mi:USH1C(display_short)|uniprotkb:AIE75(gene name synonym) psi-mi:"MI:0428"(imaging technique) Weil et al. (2003) mint:MINT-5216123|pubmed:12588794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8601743|mint:MINT-58187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|rcsb pdb:2L7T|rcsb pdb:3K1R|ensembl:ENSG00000182040(gene)|ensembl:ENST00000614341(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3PVL|reactome:R-HSA-9662361|reactome:R-HSA-9662360|refseq:NP_775748.2|refseq:NP_001269418.1|dip:DIP-41617N|mint:MINT-728031(identity) go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030507"(spectrin binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0034622"|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:1904106"(protein localization to microvillus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:1904970"(brush border assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034|rcsb pdb:1X5N|rcsb pdb:2KBQ|rcsb pdb:2KBR|rcsb pdb:2KBS|rcsb pdb:2LSR|rcsb pdb:3K1R|rcsb pdb:5F3X|rcsb pdb:5MV8|rcsb pdb:5MV9|rcsb pdb:5XBF|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0007605"(sensory perception of sound)|ensembl:ENSG00000006611(gene)|ensembl:ENST00000318024(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|refseq:NP_005700.2|refseq:NP_001284693.1|refseq:NP_710142.1|dip:DIP-41473N|mint:MINT-728023(identity) - comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in USH1G are the cause of Usher syndrome type 1G (USH1G) [MIM:606943]. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa and sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH1 is characterized by profound congenital sensorineural deafness, absent vestibular function and prepubertal onset of progressive retinitis pigmentosa leading to blindness"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/04/04 2014/10/16 rogid:0gxWTLxy7uDKQtmmwaHpjhnR9XM9606 rogid:FZD03Nq9dvV88xyKOBIgshO3Fvg9606 intact-crc:CC3E9F03BA9DF330|rigid:IgazcWfpx2obpaYnxojpT0JamXs false binding-associated region:456-461(MINT-728032) binding-associated region:87-169(MINT-728024) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification)