#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P56371 uniprotkb:Q9JLQ0 intact:EBI-8595346|ensembl:ENSMUSP00000113401|ensembl:ENSMUSP00000113886|uniprotkb:Q3TSQ6|intact:MINT-255793 intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709 psi-mi:rab4a_mouse(display_long)|uniprotkb:Rab4a(gene name)|psi-mi:Rab4a(display_short)|uniprotkb:Rab4(gene name synonym) psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Cormont et al. (2003) mint:MINT-5216078|pubmed:12559036|doi:10.1034/j.1600-0854.2003.40205 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8595372|mint:MINT-58752 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000019478(gene)|ensembl:ENSMUST00000117702(transcript)|ensembl:ENSMUST00000118535(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|go:"GO:0005829"(cytosol)|interpro:IPR027417|interpro:IPR041819|reactome:R-MMU-1660499|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8875656|interpro:IPR005225(Small GTP-binding protein)|refseq:NP_033029.2|mint:MINT-727050(identity) refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus)|mint:MINT-727056(identity) - comment:mint|function:Protein transport. Probably involved in vesicular traffic|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/06/22 2014/10/16 rogid:Zbxmk1iz9rsuGwyA/uH6anpupLc10090 rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090 intact-crc:00A235B771B737AA|rigid:fq+9PaQHAt6GLKZZ0ijbZM8ks8k false tag:?-?(MINT-727051) binding-associated region:?-?(MINT-727057)|tag:?-?(MINT-727059) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9JLQ0 uniprotkb:P22682 intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709 intact:EBI-640919|intact:EBI-2642588|uniprotkb:Q3U527|ensembl:ENSMUSP00000146244|uniprotkb:Q8CEA1 psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym) psi-mi:cbl_mouse(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:Cbl(gene name)|psi-mi:Cbl(display_short)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym) psi-mi:"MI:0018"(two hybrid) Cormont et al. (2003) mint:MINT-5216078|pubmed:12559036|doi:10.1034/j.1600-0854.2003.40205 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8595427|mint:MINT-58756 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus)|mint:MINT-727033(identity) interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:P22682|rcsb pdb:2D9S|reactome:R-MMU-1059683|reactome:R-MMU-1295596|reactome:R-MMU-1433559|reactome:R-MMU-182971|reactome:R-MMU-2173789|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-6807004|reactome:R-MMU-8849469|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-912631|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016600"(flotillin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033574"(response to testosterone)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0045471"(response to ethanol)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0070997"(neuron death)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR024162|reactome:R-MMU-9706369|ensembl:ENSMUSG00000034342(gene)|ensembl:ENSMUST00000206720(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008584"(male gonad development)|refseq:NP_031645.2|dip:DIP-33472N|mint:MINT-727039(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/06/22 2014/10/16 rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090 rogid:8MpthfXwJFMSMC6mDaTdb063dj010090 intact-crc:79BF2FFDABF98070|rigid:iYVebwunDp9iwGYkDaeJch15dQI false tag:?-?(MINT-727034) binding-associated region:?-?(MINT-727040)|tag:?-?(MINT-727042) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9JLQ0 uniprotkb:Q9JLQ0 intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709 intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709 psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym) psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Cormont et al. (2003) mint:MINT-5216078|pubmed:12559036|doi:10.1034/j.1600-0854.2003.40205 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8595396|mint:MINT-58755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus)|mint:MINT-727022(identity) refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus)|mint:MINT-727014(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/06/22 2014/10/16 rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090 rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090 intact-crc:0ABBA5A30BB0C6AB|rigid:Ug9fWhY6MJD5Z+FyDdF1fsQGcRU false tag:?-?(MINT-727025)|binding-associated region:?-?(MINT-727023) binding-associated region:?-?(MINT-727015)|tag:?-?(MINT-727017) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P56371 uniprotkb:Q9JLQ0 intact:EBI-8595346|ensembl:ENSMUSP00000113401|ensembl:ENSMUSP00000113886|uniprotkb:Q3TSQ6|intact:MINT-255793 intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709 psi-mi:rab4a_mouse(display_long)|uniprotkb:Rab4a(gene name)|psi-mi:Rab4a(display_short)|uniprotkb:Rab4(gene name synonym) psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym) psi-mi:"MI:0096"(pull down) Cormont et al. (2003) mint:MINT-5216078|pubmed:12559036|doi:10.1034/j.1600-0854.2003.40205 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8595460|mint:MINT-58753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000019478(gene)|ensembl:ENSMUST00000117702(transcript)|ensembl:ENSMUST00000118535(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|go:"GO:0005829"(cytosol)|interpro:IPR027417|interpro:IPR041819|reactome:R-MMU-1660499|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8875656|interpro:IPR005225(Small GTP-binding protein)|refseq:NP_033029.2|mint:MINT-727082(identity) refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus)|mint:MINT-727088(identity) - comment:mint|function:Protein transport. Probably involved in vesicular traffic|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C F1D|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/06/22 2014/10/16 rogid:Zbxmk1iz9rsuGwyA/uH6anpupLc10090 rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090 intact-crc:60CF08C196340D1C|rigid:fq+9PaQHAt6GLKZZ0ijbZM8ks8k false tag:?-?(MINT-727083) tag:?-?(MINT-727089) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P56371 uniprotkb:Q9JLQ0 intact:EBI-8595346|ensembl:ENSMUSP00000113401|ensembl:ENSMUSP00000113886|uniprotkb:Q3TSQ6|intact:MINT-255793 intact:EBI-644807|uniprotkb:E9QL86|uniprotkb:O88903|uniprotkb:Q8K4Z1|uniprotkb:Q8VCI9|ensembl:ENSMUSP00000024709 psi-mi:rab4a_mouse(display_long)|uniprotkb:Rab4a(gene name)|psi-mi:Rab4a(display_short)|uniprotkb:Rab4(gene name synonym) psi-mi:cd2ap_mouse(display_long)|uniprotkb:Mesenchyme-to-epithelium transition protein with SH3 domains 1(gene name synonym)|uniprotkb:Cd2ap(gene name)|psi-mi:Cd2ap(display_short)|uniprotkb:Mets1(gene name synonym) psi-mi:"MI:0096"(pull down) Cormont et al. (2003) mint:MINT-5216078|pubmed:12559036|doi:10.1034/j.1600-0854.2003.40205 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8595478|mint:MINT-58754 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000019478(gene)|ensembl:ENSMUST00000117702(transcript)|ensembl:ENSMUST00000118535(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|go:"GO:0005829"(cytosol)|interpro:IPR027417|interpro:IPR041819|reactome:R-MMU-1660499|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8875656|interpro:IPR005225(Small GTP-binding protein)|refseq:NP_033029.2|mint:MINT-727069(identity) refseq:NP_033977.3|ensembl:ENSMUSG00000061665(gene)|ensembl:ENSMUST00000024709(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9JLQ0|rcsb pdb:2JTE|rcsb pdb:2KRM|rcsb pdb:2KRN|rcsb pdb:2KRO|rcsb pdb:2LZ6|rcsb pdb:2MCN|go:"GO:1900182"(positive regulation of protein localization to nucleus)|mint:MINT-727075(identity) - comment:mint|function:Protein transport. Probably involved in vesicular traffic|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/06/22 2014/10/16 rogid:Zbxmk1iz9rsuGwyA/uH6anpupLc10090 rogid:siNa7wmze02HJhbUEEGxQaczJCQ10090 intact-crc:CAF67548FD2154EA|rigid:fq+9PaQHAt6GLKZZ0ijbZM8ks8k false tag:?-?(MINT-727070) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)