#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9VZZ9	uniprotkb:Q08012	intact:EBI-104022|intact:EBI-868924|uniprotkb:Q24452|uniprotkb:Q9W000|ensemblmetazoa:FBpp0072803	intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817	psi-mi:dos_drome(display_long)|uniprotkb:dos(gene name)|psi-mi:dos(display_short)|uniprotkb:CG1044(orf name)	psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name)	psi-mi:"MI:0096"(pull down)	Feller et al. (2002)	pubmed:12128212|mint:MINT-5215568	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8500427|mint:MINT-58628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523890.2|refseq:NP_728757.1|flybase:FBgn0016794|ensemblmetazoa:FBtr0072926(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-180292|reactome:R-DME-1963642|reactome:R-DME-2730905|reactome:R-DME-5654689|reactome:R-DME-5654695|reactome:R-DME-5654710|ensemblmetazoa:FBgn0016794(gene)|reactome:R-DME-6811558|reactome:R-DME-9027276|reactome:R-DME-5654720|mint:MINT-717933(identity)	refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N|mint:MINT-717924(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/15	2014/10/16	rogid:8+7DM2mtq2Y/RMZxXwE+oyjrT247227	rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227	intact-crc:4F79ADB6362F5E20|rigid:k/4rOjHr0TRNGs/4z/meIAeutPI	false	binding-associated region:477-878(MINT-717934)|tag:?-?(MINT-717936)	tag:?-?(MINT-717928)|binding-associated region:155-210(MINT-717925)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9VZZ9	uniprotkb:Q08012	intact:EBI-104022|intact:EBI-868924|uniprotkb:Q24452|uniprotkb:Q9W000|ensemblmetazoa:FBpp0072803	intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817	psi-mi:dos_drome(display_long)|uniprotkb:dos(gene name)|psi-mi:dos(display_short)|uniprotkb:CG1044(orf name)	psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name)	psi-mi:"MI:0096"(pull down)	Feller et al. (2002)	pubmed:12128212|mint:MINT-5215568	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8500537|mint:MINT-58630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523890.2|refseq:NP_728757.1|flybase:FBgn0016794|ensemblmetazoa:FBtr0072926(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-180292|reactome:R-DME-1963642|reactome:R-DME-2730905|reactome:R-DME-5654689|reactome:R-DME-5654695|reactome:R-DME-5654710|ensemblmetazoa:FBgn0016794(gene)|reactome:R-DME-6811558|reactome:R-DME-9027276|reactome:R-DME-5654720|mint:MINT-717912(identity)	refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N|mint:MINT-717903(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/15	2014/10/16	rogid:8+7DM2mtq2Y/RMZxXwE+oyjrT247227	rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227	intact-crc:0A7A92C232E64AF4|rigid:k/4rOjHr0TRNGs/4z/meIAeutPI	false	binding-associated region:638-650(MINT-717913)|tag:?-?(MINT-717916)	binding-associated region:155-210(MINT-717904)|tag:?-?(MINT-717907)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9VZZ9	uniprotkb:Q08012	intact:EBI-104022|intact:EBI-868924|uniprotkb:Q24452|uniprotkb:Q9W000|ensemblmetazoa:FBpp0072803	intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817	psi-mi:dos_drome(display_long)|uniprotkb:dos(gene name)|psi-mi:dos(display_short)|uniprotkb:CG1044(orf name)	psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name)	psi-mi:"MI:0096"(pull down)	Feller et al. (2002)	pubmed:12128212|mint:MINT-5215568	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8500509|mint:MINT-58629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523890.2|refseq:NP_728757.1|flybase:FBgn0016794|ensemblmetazoa:FBtr0072926(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-180292|reactome:R-DME-1963642|reactome:R-DME-2730905|reactome:R-DME-5654689|reactome:R-DME-5654695|reactome:R-DME-5654710|ensemblmetazoa:FBgn0016794(gene)|reactome:R-DME-6811558|reactome:R-DME-9027276|reactome:R-DME-5654720|mint:MINT-717973(identity)	refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N|mint:MINT-717964(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/15	2014/10/16	rogid:8+7DM2mtq2Y/RMZxXwE+oyjrT247227	rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227	intact-crc:0D473F51781BF6D4|rigid:k/4rOjHr0TRNGs/4z/meIAeutPI	false	mutation decreasing interaction:696-696,644-644(MINT-717974)|tag:?-?(MINT-717977)	binding-associated region:155-210(MINT-717965)|tag:?-?(MINT-717968)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9VZZ9	uniprotkb:Q08012	intact:EBI-104022|intact:EBI-868924|uniprotkb:Q24452|uniprotkb:Q9W000|ensemblmetazoa:FBpp0072803	intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817	psi-mi:dos_drome(display_long)|uniprotkb:dos(gene name)|psi-mi:dos(display_short)|uniprotkb:CG1044(orf name)	psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name)	psi-mi:"MI:0096"(pull down)	Feller et al. (2002)	pubmed:12128212|mint:MINT-5215568	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8500564|mint:MINT-58631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523890.2|refseq:NP_728757.1|flybase:FBgn0016794|ensemblmetazoa:FBtr0072926(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-180292|reactome:R-DME-1963642|reactome:R-DME-2730905|reactome:R-DME-5654689|reactome:R-DME-5654695|reactome:R-DME-5654710|ensemblmetazoa:FBgn0016794(gene)|reactome:R-DME-6811558|reactome:R-DME-9027276|reactome:R-DME-5654720|mint:MINT-717994(identity)	refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N|mint:MINT-717985(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/15	2014/10/16	rogid:8+7DM2mtq2Y/RMZxXwE+oyjrT247227	rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227	intact-crc:DC9E758865BAA440|rigid:k/4rOjHr0TRNGs/4z/meIAeutPI	false	tag:?-?(MINT-717998)|binding-associated region:690-702(MINT-717995)	binding-associated region:155-210(MINT-717986)|tag:?-?(MINT-717989)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08012	uniprotkb:Q9VZZ9	intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817	intact:EBI-104022|intact:EBI-868924|uniprotkb:Q24452|uniprotkb:Q9W000|ensemblmetazoa:FBpp0072803	psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name)	psi-mi:dos_drome(display_long)|uniprotkb:dos(gene name)|psi-mi:dos(display_short)|uniprotkb:CG1044(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Feller et al. (2002)	pubmed:12128212|mint:MINT-5215568	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8500599|mint:MINT-58632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N|mint:MINT-717946(identity)	refseq:NP_523890.2|refseq:NP_728757.1|flybase:FBgn0016794|ensemblmetazoa:FBtr0072926(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-DME-109704|reactome:R-DME-1257604|reactome:R-DME-180292|reactome:R-DME-1963642|reactome:R-DME-2730905|reactome:R-DME-5654689|reactome:R-DME-5654695|reactome:R-DME-5654710|ensemblmetazoa:FBgn0016794(gene)|reactome:R-DME-6811558|reactome:R-DME-9027276|reactome:R-DME-5654720|mint:MINT-717952(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/06/15	2014/10/16	rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227	rogid:8+7DM2mtq2Y/RMZxXwE+oyjrT247227	intact-crc:71B349CF02F7F2D4|rigid:k/4rOjHr0TRNGs/4z/meIAeutPI	false	tag:?-?(MINT-717947)	tag:?-?(MINT-717956)|mutation decreasing interaction:644-644,696-696(MINT-717953)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)