#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8MUJ1 uniprotkb:Q9VWS4 intact:EBI-108054|intact:EBI-3423810|intact:EBI-516974|uniprotkb:Q8IGD3|uniprotkb:Q8MRW2|uniprotkb:Q8MY88|ensemblmetazoa:FBpp0087493 intact:EBI-161953|uniprotkb:Q7Z1X1|ensemblmetazoa:FBpp0074388 psi-mi:eiger_drome(display_long)|uniprotkb:egr(gene name)|psi-mi:egr(display_short)|uniprotkb:Darth(gene name synonym)|uniprotkb:CG12919(orf name) psi-mi:wgn_drome(display_long)|uniprotkb:wgn(gene name)|psi-mi:wgn(display_short)|uniprotkb:Vader(gene name synonym)|uniprotkb:CG6531(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Kanda et al. (2002) pubmed:12084706 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-516970 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_724878.2|flybase:FBgn0033483|refseq:NP_995791.1|ensemblmetazoa:FBgn0033483(gene)|ensemblmetazoa:FBtr0088405(transcript)|go:"GO:0002347"(response to tumor cell)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035006"(melanization defense response)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045087"(innate immune response)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045176"(apical protein localization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:6ZT0|reactome:R-DME-450520 refseq:NP_728186.1|flybase:FBgn0030941|ensemblmetazoa:FBgn0030941(gene)|ensemblmetazoa:FBtr0074617(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region) - - - - taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2005/03/09 2016/01/15 rogid:M6woa0RRnSQtL56wC0YDEog/IHc7227 rogid:VULEWWjStSzOVPmROq+eSbgJZtc7227 intact-crc:CF04954F95B271B6|rigid:Q9KEcwVCczlsY4KFzzNJDoJsr0Q false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8MUJ1 uniprotkb:Q9VWS4 intact:EBI-108054|intact:EBI-3423810|intact:EBI-516974|uniprotkb:Q8IGD3|uniprotkb:Q8MRW2|uniprotkb:Q8MY88|ensemblmetazoa:FBpp0087493 intact:EBI-161953|uniprotkb:Q7Z1X1|ensemblmetazoa:FBpp0074388 psi-mi:eiger_drome(display_long)|uniprotkb:egr(gene name)|psi-mi:egr(display_short)|uniprotkb:Darth(gene name synonym)|uniprotkb:CG12919(orf name) psi-mi:wgn_drome(display_long)|uniprotkb:wgn(gene name)|psi-mi:wgn(display_short)|uniprotkb:Vader(gene name synonym)|uniprotkb:CG6531(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Kanda et al. (2002) pubmed:12084706 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-516990 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_724878.2|flybase:FBgn0033483|refseq:NP_995791.1|ensemblmetazoa:FBgn0033483(gene)|ensemblmetazoa:FBtr0088405(transcript)|go:"GO:0002347"(response to tumor cell)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035006"(melanization defense response)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045087"(innate immune response)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045176"(apical protein localization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:6ZT0|reactome:R-DME-450520 refseq:NP_728186.1|flybase:FBgn0030941|ensemblmetazoa:FBgn0030941(gene)|ensemblmetazoa:FBtr0074617(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region) - - - - taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2005/03/09 2016/01/15 rogid:M6woa0RRnSQtL56wC0YDEog/IHc7227 rogid:VULEWWjStSzOVPmROq+eSbgJZtc7227 intact-crc:613823EB9CD90944|rigid:Q9KEcwVCczlsY4KFzzNJDoJsr0Q false ha tag:?-? flag tag:?-?|binding-associated region:100-130(IPR001368) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8MUJ1 uniprotkb:Q9VWS4 intact:EBI-108054|intact:EBI-3423810|intact:EBI-516974|uniprotkb:Q8IGD3|uniprotkb:Q8MRW2|uniprotkb:Q8MY88|ensemblmetazoa:FBpp0087493 intact:EBI-161953|uniprotkb:Q7Z1X1|ensemblmetazoa:FBpp0074388 psi-mi:eiger_drome(display_long)|uniprotkb:egr(gene name)|psi-mi:egr(display_short)|uniprotkb:Darth(gene name synonym)|uniprotkb:CG12919(orf name) psi-mi:wgn_drome(display_long)|uniprotkb:wgn(gene name)|psi-mi:wgn(display_short)|uniprotkb:Vader(gene name synonym)|uniprotkb:CG6531(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Kanda et al. (2002) pubmed:12084706 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-517017 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_724878.2|flybase:FBgn0033483|refseq:NP_995791.1|ensemblmetazoa:FBgn0033483(gene)|ensemblmetazoa:FBtr0088405(transcript)|go:"GO:0002347"(response to tumor cell)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035006"(melanization defense response)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045087"(innate immune response)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045176"(apical protein localization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:6ZT0|reactome:R-DME-450520 refseq:NP_728186.1|flybase:FBgn0030941|ensemblmetazoa:FBgn0030941(gene)|ensemblmetazoa:FBtr0074617(transcript)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region) - - - - taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2005/03/09 2016/01/15 rogid:M6woa0RRnSQtL56wC0YDEog/IHc7227 rogid:VULEWWjStSzOVPmROq+eSbgJZtc7227 intact-crc:5F7A8F22231B865C|rigid:Q9KEcwVCczlsY4KFzzNJDoJsr0Q false ha tag:?-?|binding-associated region:277-415(IPR001368) flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)