#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P03120	uniprotkb:Q92547	intact:EBI-1779322|uniprotkb:Q71BI4	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Boner et al. (2002)	pubmed:11934899|mint:MINT-5215244	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8281549|mint:MINT-73202	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-1579391(identity)	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N|mint:MINT-1579396(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-c33a)|taxid:9606(Homo sapiens epihelial cervix carcinoma cells)	-	2005/12/07	2014/10/16	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	intact-crc:049DB8E4C4DBDFB8|rigid:PXXfZ5L7ZiXokaM3ZpgYuLCdgPk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03120	uniprotkb:Q92547	intact:EBI-1779322|uniprotkb:Q71BI4	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Boner et al. (2002)	pubmed:11934899|mint:MINT-5215244	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8281665|mint:MINT-73200	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-1684425(identity)	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N|mint:MINT-1684434(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/07	2014/10/16	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	intact-crc:812F1587D3BFE01E|rigid:PXXfZ5L7ZiXokaM3ZpgYuLCdgPk	false	binding-associated region:50-229(MINT-1684426)|glutathione s tranferase tag:?-?(MINT-1684428)	binding-associated region:863-1522(MINT-1684435)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y244	uniprotkb:P03120	intact:EBI-696895|uniprotkb:A5HKJ2|uniprotkb:Q9HB69|uniprotkb:D6MXU3|ensembl:ENSP00000370222	intact:EBI-1779322|uniprotkb:Q71BI4	psi-mi:pomp_human(display_long)|uniprotkb:Proteassemblin(gene name synonym)|uniprotkb:Protein UMP1 homolog(gene name synonym)|uniprotkb:Voltage-gated K channel beta subunit 4.1(gene name synonym)|uniprotkb:POMP(gene name)|psi-mi:POMP(display_short)|uniprotkb:C13orf12(gene name synonym)|uniprotkb:UMP1(gene name synonym)|uniprotkb:HSPC014(orf name)|uniprotkb:HSPC036(orf name)|uniprotkb:PNAS-110(orf name)	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:"MI:0096"(pull down)	Boner et al. (2002)	pubmed:11934899|mint:MINT-5215244	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8281709|mint:MINT-73201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057016.1|ensembl:ENSG00000132963(gene)|ensembl:ENST00000380842(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0043248"(proteasome assembly)|interpro:IPR008012(Proteasome maturation factor UMP1)|mint:Q9Y244|mint:MINT-1695745(identity)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-1695738(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/07	2014/10/16	rogid:m+0wD07fgD7iQF8cB1rqhIIWLxk9606	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	intact-crc:4CDBC24B49E9D4B0|rigid:q6tUXkxwHrDt8tkgkQtsuWWdJdI	false	-	glutathione s tranferase tag:?-?(MINT-1695739)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)