#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13641 uniprotkb:O14908 intact:EBI-2907663|ensembl:ENSP00000358765|ensembl:ENSP00000440049|ensembl:ENSP00000441219|ensembl:ENSP00000489140|ensembl:ENSP00000489143|ensembl:ENSP00000489447|uniprotkb:A8K555 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 psi-mi:tpbg_human(display_long)|uniprotkb:TPBG(gene name)|psi-mi:TPBG(display_short)|uniprotkb:5T4(gene name synonym)|uniprotkb:5T4 oncofetal trophoblast glycoprotein(gene name synonym)|uniprotkb:5T4 oncofetal antigen(gene name synonym)|uniprotkb:M6P1(gene name synonym)|uniprotkb:Wnt-activated inhibitory factor 1(gene name synonym) psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:"MI:0428"(imaging technique) Awan et al. (2002) pubmed:11798178|mint:MINT-5215021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8077439|mint:MINT-62472 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146242(gene)|ensembl:ENSG00000283085(gene)|ensembl:ENST00000369750(transcript)|ensembl:ENST00000535040(transcript)|ensembl:ENST00000543496(transcript)|ensembl:ENST00000634817(transcript)|ensembl:ENST00000634826(transcript)|ensembl:ENST00000635036(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043679"(axon terminus)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0140059"(dendrite arborization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|rcsb pdb:4CNC|rcsb pdb:4CNM|rcsb pdb:6HBY|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|refseq:XP_011534399.1|refseq:NP_001159864.1|refseq:NP_006661.1|mint:MINT-612250(identity) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N|mint:MINT-612241(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/09/16 2014/10/16 rogid:DYB2K9qZt/IrDJXublplXeJbCiE9606 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 intact-crc:2AE58507DD1CCCFC|rigid:YM8bzrGLzcAHv9UcvBLlpBZrUHU false binding-associated region:384-420(MINT-612251) binding-associated region:133-214(MINT-612242)|tag:?-?(MINT-612245) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q13641 uniprotkb:O14908 intact:EBI-2907663|ensembl:ENSP00000358765|ensembl:ENSP00000440049|ensembl:ENSP00000441219|ensembl:ENSP00000489140|ensembl:ENSP00000489143|ensembl:ENSP00000489447|uniprotkb:A8K555 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 psi-mi:tpbg_human(display_long)|uniprotkb:TPBG(gene name)|psi-mi:TPBG(display_short)|uniprotkb:5T4(gene name synonym)|uniprotkb:5T4 oncofetal trophoblast glycoprotein(gene name synonym)|uniprotkb:5T4 oncofetal antigen(gene name synonym)|uniprotkb:M6P1(gene name synonym)|uniprotkb:Wnt-activated inhibitory factor 1(gene name synonym) psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Awan et al. (2002) pubmed:11798178|mint:MINT-5215021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8077490|mint:MINT-62470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146242(gene)|ensembl:ENSG00000283085(gene)|ensembl:ENST00000369750(transcript)|ensembl:ENST00000535040(transcript)|ensembl:ENST00000543496(transcript)|ensembl:ENST00000634817(transcript)|ensembl:ENST00000634826(transcript)|ensembl:ENST00000635036(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043679"(axon terminus)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0140059"(dendrite arborization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|rcsb pdb:4CNC|rcsb pdb:4CNM|rcsb pdb:6HBY|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|refseq:XP_011534399.1|refseq:NP_001159864.1|refseq:NP_006661.1|mint:MINT-612272(identity) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N|mint:MINT-612263(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/09/16 2014/10/16 rogid:DYB2K9qZt/IrDJXublplXeJbCiE9606 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 intact-crc:6436E4CB28634F4D|rigid:YM8bzrGLzcAHv9UcvBLlpBZrUHU false tag:?-?(MINT-612276)|binding-associated region:384-420(MINT-612273) tag:?-?(MINT-612267)|binding-associated region:133-214(MINT-612264) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14908 uniprotkb:Q13641 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 intact:EBI-2907663|ensembl:ENSP00000358765|ensembl:ENSP00000440049|ensembl:ENSP00000441219|ensembl:ENSP00000489140|ensembl:ENSP00000489143|ensembl:ENSP00000489447|uniprotkb:A8K555 psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:tpbg_human(display_long)|uniprotkb:TPBG(gene name)|psi-mi:TPBG(display_short)|uniprotkb:5T4(gene name synonym)|uniprotkb:5T4 oncofetal trophoblast glycoprotein(gene name synonym)|uniprotkb:5T4 oncofetal antigen(gene name synonym)|uniprotkb:M6P1(gene name synonym)|uniprotkb:Wnt-activated inhibitory factor 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Awan et al. (2002) pubmed:11798178|mint:MINT-5215021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8077587|mint:MINT-62471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N|mint:MINT-612287(identity) ensembl:ENSG00000146242(gene)|ensembl:ENSG00000283085(gene)|ensembl:ENST00000369750(transcript)|ensembl:ENST00000535040(transcript)|ensembl:ENST00000543496(transcript)|ensembl:ENST00000634817(transcript)|ensembl:ENST00000634826(transcript)|ensembl:ENST00000635036(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043679"(axon terminus)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0140059"(dendrite arborization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|rcsb pdb:4CNC|rcsb pdb:4CNM|rcsb pdb:6HBY|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|refseq:XP_011534399.1|refseq:NP_001159864.1|refseq:NP_006661.1|mint:MINT-612296(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:pCMValpha tagged 5T4 and HA tagged GIPC.
|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/09/16 2014/10/16 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rogid:DYB2K9qZt/IrDJXublplXeJbCiE9606 intact-crc:37220FFB6582C894|rigid:YM8bzrGLzcAHv9UcvBLlpBZrUHU false binding-associated region:133-214(MINT-612288)|tag:?-?(MINT-612291) tag:?-?(MINT-612300)|binding-associated region:384-420(MINT-612297) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot)