#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06462	uniprotkb:Q15942	intact:EBI-7069993|intact:MINT-104603	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	psi-mi:ve6_hpv6b(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Degenhardt et al. (2001)	pubmed:11689660|mint:MINT-5214749|doi:10.1128/JVI.75.23.11791-11802.2001	taxid:10600(hpv6b)|taxid:10600(Human papillomavirus type 6b)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8027527|mint:MINT-73233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06462|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_040296.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|mint:MINT-593959(identity)	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1|mint:MINT-593964(identity)	-	comment:mint|function:Transcriptional transactivator. Binds double stranded DNA|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/08	2014/10/16	rogid:4BeLLSoGSoKx9MQ2JT6lTbXpGGw10600	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	intact-crc:C0362016712E7532|rigid:xh8Xb7SMBkPR57D5zkKsV/8d5DM	false	-	flag tag:?-?(MINT-593965)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13227	uniprotkb:P06463	intact:EBI-713355|ensembl:ENSP00000370104|ensembl:ENSP00000379841|ensembl:ENSP00000500255|ensembl:ENSP00000500677|uniprotkb:B4DXA1|uniprotkb:Q6FHM8	intact:EBI-1186926	psi-mi:gps2_human(display_long)|uniprotkb:GPS2(gene name)|psi-mi:GPS2(display_short)	psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Degenhardt et al. (2001)	pubmed:11689660|mint:MINT-5214749|doi:10.1128/JVI.75.23.11791-11802.2001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8027557|mint:MINT-73235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004480.1|ensembl:ENSG00000132522(gene)|ensembl:ENSG00000288325(gene)|ensembl:ENST00000380728(transcript)|ensembl:ENST00000389167(transcript)|ensembl:ENST00000672046(transcript)|ensembl:ENST00000673265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900045"(negative regulation of protein K63-linked ubiquitination)|interpro:IPR026094|rcsb pdb:2L5G|reactome:R-HSA-1989781|reactome:R-HSA-3214815|reactome:R-HSA-9022537|go:"GO:0003713"(transcription coactivator activity)|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|dip:DIP-34427N|mint:MINT-593887(identity)	refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N|mint:MINT-593882(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/08	2014/10/16	rogid:zMNwbPfMT2dBTxgcwiMD92QHJtM9606	rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761	intact-crc:8EB65AF0E81E4BD9|rigid:JE1EiyYacYcd8tOcyJ5U9LHvq/Q	false	flag tag:?-?(MINT-593888)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06462	uniprotkb:Q13227	intact:EBI-7069993|intact:MINT-104603	intact:EBI-713355|ensembl:ENSP00000370104|ensembl:ENSP00000379841|ensembl:ENSP00000500255|ensembl:ENSP00000500677|uniprotkb:B4DXA1|uniprotkb:Q6FHM8	psi-mi:ve6_hpv6b(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:gps2_human(display_long)|uniprotkb:GPS2(gene name)|psi-mi:GPS2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Degenhardt et al. (2001)	pubmed:11689660|mint:MINT-5214749|doi:10.1128/JVI.75.23.11791-11802.2001	taxid:10600(hpv6b)|taxid:10600(Human papillomavirus type 6b)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8027542|mint:MINT-73234	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06462|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_040296.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|mint:MINT-593897(identity)	refseq:NP_004480.1|ensembl:ENSG00000132522(gene)|ensembl:ENSG00000288325(gene)|ensembl:ENST00000380728(transcript)|ensembl:ENST00000389167(transcript)|ensembl:ENST00000672046(transcript)|ensembl:ENST00000673265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900045"(negative regulation of protein K63-linked ubiquitination)|interpro:IPR026094|rcsb pdb:2L5G|reactome:R-HSA-1989781|reactome:R-HSA-3214815|reactome:R-HSA-9022537|go:"GO:0003713"(transcription coactivator activity)|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|dip:DIP-34427N|mint:MINT-593902(identity)	-	comment:mint|function:Transcriptional transactivator. Binds double stranded DNA|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/08	2014/10/16	rogid:4BeLLSoGSoKx9MQ2JT6lTbXpGGw10600	rogid:zMNwbPfMT2dBTxgcwiMD92QHJtM9606	intact-crc:FEE6C7A45489F785|rigid:UhkJnRDr8fzfE5HzarF1y8CumFQ	false	-	flag tag:?-?(MINT-593903)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06462	uniprotkb:Q15942	intact:EBI-7069993|intact:MINT-104603	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	psi-mi:ve6_hpv6b(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0096"(pull down)	Degenhardt et al. (2001)	pubmed:11689660|mint:MINT-5214749|doi:10.1128/JVI.75.23.11791-11802.2001	taxid:10600(hpv6b)|taxid:10600(Human papillomavirus type 6b)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8027596|mint:MINT-73232	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06462|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_040296.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|mint:MINT-593914(identity)	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1|mint:MINT-593921(identity)	-	comment:mint|function:Transcriptional transactivator. Binds double stranded DNA|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1 F6C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/08	2014/10/16	rogid:4BeLLSoGSoKx9MQ2JT6lTbXpGGw10600	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	intact-crc:1B2D1FBA5290EB02|rigid:xh8Xb7SMBkPR57D5zkKsV/8d5DM	false	glutathione s tranferase tag:?-?(MINT-593915)	binding-associated region:383-572(MINT-593922)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06462	uniprotkb:Q15942	intact:EBI-7069993|intact:MINT-104603	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	psi-mi:ve6_hpv6b(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0018"(two hybrid)	Degenhardt et al. (2001)	pubmed:11689660|mint:MINT-5214749|doi:10.1128/JVI.75.23.11791-11802.2001	taxid:10600(hpv6b)|taxid:10600(Human papillomavirus type 6b)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8027623|mint:MINT-73231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06462|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|refseq:NP_040296.1|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|mint:MINT-593935(identity)	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1|mint:MINT-593944(identity)	-	comment:mint|function:Transcriptional transactivator. Binds double stranded DNA|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/12/08	2014/10/16	rogid:4BeLLSoGSoKx9MQ2JT6lTbXpGGw10600	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	intact-crc:C7D4A18E61C2641B|rigid:xh8Xb7SMBkPR57D5zkKsV/8d5DM	false	mutation decreasing interaction:1-37(MINT-593936)|tag:?-?(MINT-593938)	binding-associated region:299-572(MINT-593945)|tag:?-?(MINT-593949)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)