#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09184 uniprotkb:P23367 intact:EBI-765033|ensemblbacteria:AAC75026|ensemblbacteria:BAA15787 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:vsr_ecoli(display_long)|uniprotkb:DNA mismatch endonuclease(gene name synonym)|uniprotkb:Vsr mismatch endonuclease(gene name synonym)|uniprotkb:V.EcoKDcm(gene name synonym)|uniprotkb:vsr(gene name)|psi-mi:vsr(display_short)|uniprotkb:b1960(locus name)|uniprotkb:JW1943(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0018"(two hybrid) Mansour et al. (2001) pubmed:11585365 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-765039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_416469.1|refseq:WP_000786005.1|dip:DIP-11114N|ensemblbacteria:AAC75026(transcript)|ensemblbacteria:b1960(gene)|ensemblbacteria:BAA15787(gene)|ensemblbacteria:BAA15787(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|rcsb pdb:1CW0|rcsb pdb:1ODG|rcsb pdb:1VSR|interpro:IPR004603(DNA mismatch endonuclease vsr) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/12/08 2014/10/16 rogid:2a0R+aMcWPpCj/cSQ9UvaJS+Qao83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:2C1C1320525934A1|rigid:yUJT0m36qKgzG64c9M+SbQxYqc8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23367 uniprotkb:P06722 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 intact:EBI-545170|uniprotkb:Q2MA06|uniprotkb:Q9R2X2|uniprotkb:Q9R3A8|uniprotkb:Q9R411|uniprotkb:Q9S6P5|uniprotkb:Q9S6P6|uniprotkb:Q9S6P7|ensemblbacteria:AAC75870|ensemblbacteria:BAE76900 psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:muth_ecoli(display_long)|uniprotkb:mutH(gene name)|psi-mi:mutH(display_short)|uniprotkb:mutR(gene name synonym)|uniprotkb:prv(gene name synonym)|uniprotkb:b2831(locus name)|uniprotkb:Methyl-directed mismatch repair protein(gene name synonym)|uniprotkb:JW2799(locus name) psi-mi:"MI:0018"(two hybrid) Mansour et al. (2001) pubmed:11585365 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-765042 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC go:"GO:0000018"(regulation of DNA recombination)|ensemblbacteria:BAE76900(transcript)|ensemblbacteria:AAC75870(transcript)|ensemblbacteria:b2831(gene)|ensemblbacteria:BAE76900(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006304"(DNA modification)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|interpro:IPR004230(DNA mismatch repair protein MutH)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011337(Restriction endonuclease, type II, EcoRV-like/DNA mismatch repair MutH, core)|interpro:IPR037057|rcsb pdb:1AZO|rcsb pdb:2AZO|go:"GO:0003677"(DNA binding)|refseq:NP_417308.1|refseq:WP_000082201.1|dip:DIP-10284N - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/12/08 2014/10/16 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 rogid:ImnYkXur2U4xVdz5PVvprq8Zgd483333 intact-crc:BCAECA6899826160|rigid:1gV7goLXeCXg0TLAfsnNcwP8LGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09184 uniprotkb:P23367 intact:EBI-765033|ensemblbacteria:AAC75026|ensemblbacteria:BAA15787 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:vsr_ecoli(display_long)|uniprotkb:DNA mismatch endonuclease(gene name synonym)|uniprotkb:Vsr mismatch endonuclease(gene name synonym)|uniprotkb:V.EcoKDcm(gene name synonym)|uniprotkb:vsr(gene name)|psi-mi:vsr(display_short)|uniprotkb:b1960(locus name)|uniprotkb:JW1943(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0014"(adenylate cyclase complementation) Mansour et al. (2001) pubmed:11585365 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-765062 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_416469.1|refseq:WP_000786005.1|dip:DIP-11114N|ensemblbacteria:AAC75026(transcript)|ensemblbacteria:b1960(gene)|ensemblbacteria:BAA15787(gene)|ensemblbacteria:BAA15787(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|rcsb pdb:1CW0|rcsb pdb:1ODG|rcsb pdb:1VSR|interpro:IPR004603(DNA mismatch endonuclease vsr) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - inhibition:Interaction is greatly diminished in mutS strain taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/12/08 2014/10/16 rogid:2a0R+aMcWPpCj/cSQ9UvaJS+Qao83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:022DD90A7AF82158|rigid:yUJT0m36qKgzG64c9M+SbQxYqc8 false sufficient binding region:21-156|necessary binding region:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06722 uniprotkb:P23367 intact:EBI-545170|uniprotkb:Q2MA06|uniprotkb:Q9R2X2|uniprotkb:Q9R3A8|uniprotkb:Q9R411|uniprotkb:Q9S6P5|uniprotkb:Q9S6P6|uniprotkb:Q9S6P7|ensemblbacteria:AAC75870|ensemblbacteria:BAE76900 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:muth_ecoli(display_long)|uniprotkb:mutH(gene name)|psi-mi:mutH(display_short)|uniprotkb:mutR(gene name synonym)|uniprotkb:prv(gene name synonym)|uniprotkb:b2831(locus name)|uniprotkb:Methyl-directed mismatch repair protein(gene name synonym)|uniprotkb:JW2799(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0014"(adenylate cyclase complementation) Mansour et al. (2001) pubmed:11585365 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-765065 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000018"(regulation of DNA recombination)|ensemblbacteria:BAE76900(transcript)|ensemblbacteria:AAC75870(transcript)|ensemblbacteria:b2831(gene)|ensemblbacteria:BAE76900(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006304"(DNA modification)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|interpro:IPR004230(DNA mismatch repair protein MutH)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011337(Restriction endonuclease, type II, EcoRV-like/DNA mismatch repair MutH, core)|interpro:IPR037057|rcsb pdb:1AZO|rcsb pdb:2AZO|go:"GO:0003677"(DNA binding)|refseq:NP_417308.1|refseq:WP_000082201.1|dip:DIP-10284N refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - inhibition:overexpression of Vsr|inhibition:Interaction is greatly diminished in mutS strain taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/12/08 2014/10/16 rogid:ImnYkXur2U4xVdz5PVvprq8Zgd483333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:E05E7974255F638B|rigid:1gV7goLXeCXg0TLAfsnNcwP8LGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23367 uniprotkb:P23367 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0014"(adenylate cyclase complementation) Mansour et al. (2001) pubmed:11585365 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-765068 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - inhibition:overexpression of Vsr|inhibition:interaction inhibited in mutH strain taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/12/08 2014/10/16 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:914765FF004F082D|rigid:Ha3JrkX3/DlzQH8+roGS7gZxKNU false - sufficient binding region:351-615 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23909 uniprotkb:P23909 intact:EBI-554920|uniprotkb:P71279|uniprotkb:Q2MA96|ensemblbacteria:AAC75775|ensemblbacteria:BAE76810 intact:EBI-554920|uniprotkb:P71279|uniprotkb:Q2MA96|ensemblbacteria:AAC75775|ensemblbacteria:BAE76810 psi-mi:muts_ecoli(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:fdv(gene name synonym)|uniprotkb:b2733(locus name)|uniprotkb:JW2703(locus name) psi-mi:muts_ecoli(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:fdv(gene name synonym)|uniprotkb:b2733(locus name)|uniprotkb:JW2703(locus name) psi-mi:"MI:0014"(adenylate cyclase complementation) Mansour et al. (2001) pubmed:11585365 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-765077 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417213.1|refseq:WP_001272928.1|dip:DIP-10287N|ensemblbacteria:AAC75775(transcript)|ensemblbacteria:b2733(gene)|ensemblbacteria:BAE76810(gene)|ensemblbacteria:BAE76810(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032136"(adenine/cytosine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|rcsb pdb:1E3M|rcsb pdb:1NG9|rcsb pdb:1OH5|rcsb pdb:1OH6|rcsb pdb:1OH7|rcsb pdb:1OH8|rcsb pdb:1W7A|rcsb pdb:1WB9|rcsb pdb:1WBB|rcsb pdb:1WBD|rcsb pdb:2OK2|rcsb pdb:2WTU|rcsb pdb:3K0S|rcsb pdb:3ZLJ|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6I5F|rcsb pdb:7AI6|rcsb pdb:7AI7|rcsb pdb:7AIB|rcsb pdb:7AIC refseq:NP_417213.1|refseq:WP_001272928.1|dip:DIP-10287N|ensemblbacteria:AAC75775(transcript)|ensemblbacteria:b2733(gene)|ensemblbacteria:BAE76810(gene)|ensemblbacteria:BAE76810(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032136"(adenine/cytosine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|rcsb pdb:1E3M|rcsb pdb:1NG9|rcsb pdb:1OH5|rcsb pdb:1OH6|rcsb pdb:1OH7|rcsb pdb:1OH8|rcsb pdb:1W7A|rcsb pdb:1WB9|rcsb pdb:1WBB|rcsb pdb:1WBD|rcsb pdb:2OK2|rcsb pdb:2WTU|rcsb pdb:3K0S|rcsb pdb:3ZLJ|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6I5F|rcsb pdb:7AI6|rcsb pdb:7AI7|rcsb pdb:7AIB|rcsb pdb:7AIC - - - inhibition:interaction inhibited in mutH strain taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/12/08 2014/10/16 rogid:dATh7ZKvCBDCX9StM+kqKD3kZ+w83333 rogid:dATh7ZKvCBDCX9StM+kqKD3kZ+w83333 intact-crc:2E9377B4A003E44C|rigid:EsuCtTBzCUrq4B7nEnffM4v37Eg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06722 uniprotkb:P23367 intact:EBI-545170|uniprotkb:Q2MA06|uniprotkb:Q9R2X2|uniprotkb:Q9R3A8|uniprotkb:Q9R411|uniprotkb:Q9S6P5|uniprotkb:Q9S6P6|uniprotkb:Q9S6P7|ensemblbacteria:AAC75870|ensemblbacteria:BAE76900 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:muth_ecoli(display_long)|uniprotkb:mutH(gene name)|psi-mi:mutH(display_short)|uniprotkb:mutR(gene name synonym)|uniprotkb:prv(gene name synonym)|uniprotkb:b2831(locus name)|uniprotkb:Methyl-directed mismatch repair protein(gene name synonym)|uniprotkb:JW2799(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0014"(adenylate cyclase complementation) Mansour et al. (2001) pubmed:11585365 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-765153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000018"(regulation of DNA recombination)|ensemblbacteria:BAE76900(transcript)|ensemblbacteria:AAC75870(transcript)|ensemblbacteria:b2831(gene)|ensemblbacteria:BAE76900(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006304"(DNA modification)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|interpro:IPR004230(DNA mismatch repair protein MutH)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011337(Restriction endonuclease, type II, EcoRV-like/DNA mismatch repair MutH, core)|interpro:IPR037057|rcsb pdb:1AZO|rcsb pdb:2AZO|go:"GO:0003677"(DNA binding)|refseq:NP_417308.1|refseq:WP_000082201.1|dip:DIP-10284N refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - inhibition:overexpression of Vsr|inhibition:Interaction is greatly diminished in mutS strain taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/12/08 2014/10/16 rogid:ImnYkXur2U4xVdz5PVvprq8Zgd483333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:B993BC27F23161C3|rigid:1gV7goLXeCXg0TLAfsnNcwP8LGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06722 uniprotkb:P23367 intact:EBI-545170|uniprotkb:Q2MA06|uniprotkb:Q9R2X2|uniprotkb:Q9R3A8|uniprotkb:Q9R411|uniprotkb:Q9S6P5|uniprotkb:Q9S6P6|uniprotkb:Q9S6P7|ensemblbacteria:AAC75870|ensemblbacteria:BAE76900 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:muth_ecoli(display_long)|uniprotkb:mutH(gene name)|psi-mi:mutH(display_short)|uniprotkb:mutR(gene name synonym)|uniprotkb:prv(gene name synonym)|uniprotkb:b2831(locus name)|uniprotkb:Methyl-directed mismatch repair protein(gene name synonym)|uniprotkb:JW2799(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0014"(adenylate cyclase complementation) Mansour et al. (2001) pubmed:11585365 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-765171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000018"(regulation of DNA recombination)|ensemblbacteria:BAE76900(transcript)|ensemblbacteria:AAC75870(transcript)|ensemblbacteria:b2831(gene)|ensemblbacteria:BAE76900(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006304"(DNA modification)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|interpro:IPR004230(DNA mismatch repair protein MutH)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011337(Restriction endonuclease, type II, EcoRV-like/DNA mismatch repair MutH, core)|interpro:IPR037057|rcsb pdb:1AZO|rcsb pdb:2AZO|go:"GO:0003677"(DNA binding)|refseq:NP_417308.1|refseq:WP_000082201.1|dip:DIP-10284N refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - inhibition:overexpression of Vsr|inhibition:interaction inhibited in mutH strain taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/12/08 2014/10/16 rogid:ImnYkXur2U4xVdz5PVvprq8Zgd483333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:AB8DA0DD44D573DF|rigid:1gV7goLXeCXg0TLAfsnNcwP8LGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)