#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01959 uniprotkb:Q9NRD5 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7839657|mint:MINT-73284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N|mint:MINT-576951(identity) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993|mint:MINT-576961(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2C F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/12/13 2014/10/16 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 intact-crc:319E2F32A51016AE|rigid:0SIIiOLPsOhmugHFUx8gmxonT/8 false mutation decreasing interaction:617-620(MINT-576955)|binding-associated region:583-620(MINT-576952) mutation decreasing interaction:28-28,27-27(MINT-576962) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q61327 uniprotkb:Q62083 intact:EBI-7839708|ensembl:ENSMUSP00000022100|uniprotkb:Q60719|uniprotkb:Q9R1I2|intact:MINT-576974 intact:EBI-77550|uniprotkb:E9PY04 psi-mi:sc6a3_mouse(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Dat(gene name synonym)|uniprotkb:Dat1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7839749|mint:MINT-73292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021609(gene)|ensembl:ENSMUST00000022100(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|reactome:R-MMU-379401|reactome:R-MMU-442660|go:"GO:0045121"(membrane raft)|refseq:NP_034150.1|dip:DIP-41828N|mint:MINT-577030(identity) go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993|mint:MINT-577035(identity) - function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2005/12/13 2014/10/16 rogid:k3+G+CyceTOyUuiUJvry6NMrRNA10090 rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090 intact-crc:1B4AB7197C3AD9FA|rigid:NRCn8CjvuDoXIJYFQnH6FB5pqjs false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q61327 uniprotkb:Q62083 intact:EBI-7839708|ensembl:ENSMUSP00000022100|uniprotkb:Q60719|uniprotkb:Q9R1I2|intact:MINT-576974 intact:EBI-77550|uniprotkb:E9PY04 psi-mi:sc6a3_mouse(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Dat(gene name synonym)|uniprotkb:Dat1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7839796|mint:MINT-73293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021609(gene)|ensembl:ENSMUST00000022100(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|reactome:R-MMU-379401|reactome:R-MMU-442660|go:"GO:0045121"(membrane raft)|refseq:NP_034150.1|dip:DIP-41828N|mint:MINT-576996(identity) go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993|mint:MINT-577001(identity) - function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2005/12/13 2014/10/16 rogid:k3+G+CyceTOyUuiUJvry6NMrRNA10090 rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090 intact-crc:A7179BEDC691C38B|rigid:NRCn8CjvuDoXIJYFQnH6FB5pqjs false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9NRD5 uniprotkb:Q01959 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7839840|mint:MINT-73280 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993|mint:MINT-577020(identity) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N|mint:MINT-577011(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D F1E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/12/13 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 intact-crc:45D7CEF18B4E1DAB|rigid:0SIIiOLPsOhmugHFUx8gmxonT/8 false tag:?-?(MINT-577021) tag:?-?(MINT-577014)|mutation decreasing interaction:617-620(MINT-577012) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q9NRD5 uniprotkb:Q01959 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7839862|mint:MINT-73281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993|mint:MINT-577081(identity) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N|mint:MINT-577074(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/12/13 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 intact-crc:4EFC9EA5574F185E|rigid:0SIIiOLPsOhmugHFUx8gmxonT/8 false tag:?-?(MINT-577082) tag:?-?(MINT-577075) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P23975 uniprotkb:Q9NRD5 intact:EBI-6661391|ensembl:ENSP00000369237|ensembl:ENSP00000457473|uniprotkb:B2R707|uniprotkb:Q96KH8|uniprotkb:B4DX48 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 psi-mi:sc6a2_human(display_long)|uniprotkb:SLC6A2(gene name)|psi-mi:SLC6A2(display_short)|uniprotkb:NAT1(gene name synonym)|uniprotkb:NET1(gene name synonym)|uniprotkb:SLC6A5(gene name synonym)|uniprotkb:Norepinephrine transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 2(gene name synonym) psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7839909|mint:MINT-73299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103546(gene)|ensembl:ENST00000379906(transcript)|ensembl:ENST00000568943(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005328"("neurotransmitter:sodium symporter activity")|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0015844"(monoamine transport)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051620"(norepinephrine uptake)|go:"GO:0070050"(neuron cellular homeostasis)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002435("Sodium:neurotransmitter symporter, noradrenaline")|interpro:IPR037272|reactome:R-HSA-442660|reactome:R-HSA-5619109|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035725"(sodium ion transmembrane transport)|refseq:XP_011521597.1|refseq:NP_001034.1|refseq:NP_001165972.1|refseq:NP_001165975.1|refseq:NP_001165973.1|refseq:XP_006721326.1|mint:MINT-577223(identity) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993|mint:MINT-577228(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/12/13 2014/10/16 rogid:hehF0DnHCYX/ZiRKE7nzQBciHyA9606 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 intact-crc:DB1CD2334A097C84|rigid:Sj2bRh7PTzWMIIlgcidnRYVg08I false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9NRD5 uniprotkb:P23975 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-6661391|ensembl:ENSP00000369237|ensembl:ENSP00000457473|uniprotkb:B2R707|uniprotkb:Q96KH8|uniprotkb:B4DX48 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:sc6a2_human(display_long)|uniprotkb:SLC6A2(gene name)|psi-mi:SLC6A2(display_short)|uniprotkb:NAT1(gene name synonym)|uniprotkb:NET1(gene name synonym)|uniprotkb:SLC6A5(gene name synonym)|uniprotkb:Norepinephrine transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7839880|mint:MINT-73297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993|mint:MINT-577190(identity) ensembl:ENSG00000103546(gene)|ensembl:ENST00000379906(transcript)|ensembl:ENST00000568943(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005328"("neurotransmitter:sodium symporter activity")|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0015844"(monoamine transport)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051620"(norepinephrine uptake)|go:"GO:0070050"(neuron cellular homeostasis)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002435("Sodium:neurotransmitter symporter, noradrenaline")|interpro:IPR037272|reactome:R-HSA-442660|reactome:R-HSA-5619109|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035725"(sodium ion transmembrane transport)|refseq:XP_011521597.1|refseq:NP_001034.1|refseq:NP_001165972.1|refseq:NP_001165975.1|refseq:NP_001165973.1|refseq:XP_006721326.1|mint:MINT-577185(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/12/13 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:hehF0DnHCYX/ZiRKE7nzQBciHyA9606 intact-crc:D7C3C1BB5574AAE6|rigid:Sj2bRh7PTzWMIIlgcidnRYVg08I false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8BRU6 uniprotkb:Q61327 intact:EBI-7840052|ensembl:ENSMUSP00000026084|intact:MINT-577047|uniprotkb:Q8CC55 intact:EBI-7839708|ensembl:ENSMUSP00000022100|uniprotkb:Q60719|uniprotkb:Q9R1I2|intact:MINT-576974 psi-mi:vmat2_mouse(display_long)|uniprotkb:Slc18a2(gene name)|psi-mi:Slc18a2(display_short)|uniprotkb:Vmat2(gene name synonym)|uniprotkb:Monoamine transporter(gene name synonym)|uniprotkb:Solute carrier family 18 member 2(gene name synonym)|uniprotkb:Vesicular amine transporter 2(gene name synonym) psi-mi:sc6a3_mouse(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Dat(gene name synonym)|uniprotkb:Dat1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:"MI:0428"(imaging technique) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7840043|mint:MINT-73289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-212676|reactome:R-MMU-442660|interpro:IPR036259|ensembl:ENSMUSG00000025094(gene)|ensembl:ENSMUST00000026084(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009791"(post-embryonic development)|go:"GO:0015842"(aminergic neurotransmitter loading into synaptic vesicle)|go:"GO:0015844"(monoamine transport)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030073"(insulin secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035690"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0051589"(negative regulation of neurotransmitter transport)|go:"GO:0051610"(serotonin uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098700"(neurotransmitter loading into synaptic vesicle)|go:"GO:0098794"(postsynapse)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099066"(integral component of neuronal dense core vesicle membrane)|interpro:IPR004734(Multidrug resistance protein)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|refseq:NP_766111.1|mint:MINT-577066(identity) ensembl:ENSMUSG00000021609(gene)|ensembl:ENSMUST00000022100(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|reactome:R-MMU-379401|reactome:R-MMU-442660|go:"GO:0045121"(membrane raft)|refseq:NP_034150.1|dip:DIP-41828N|mint:MINT-577061(identity) - comment:mint|function:Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis|comment:"Stoichiometry: 1.0" function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint|comment:"Stoichiometry: 1.0" figure legend:F5C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10090(mouse-midbrain neuro)|taxid:10090(Mus musculus) - 2005/12/13 2014/10/16 rogid:xs/Y3dfM/i7d+E6B/RCaPCl2DmM10090 rogid:k3+G+CyceTOyUuiUJvry6NMrRNA10090 intact-crc:6B10EDDE124A0900|rigid:+aB2h10EjBqVKPdUUQOdA8s84lc false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q61327 uniprotkb:Q62083 intact:EBI-7839708|ensembl:ENSMUSP00000022100|uniprotkb:Q60719|uniprotkb:Q9R1I2|intact:MINT-576974 intact:EBI-77550|uniprotkb:E9PY04 psi-mi:sc6a3_mouse(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Dat(gene name synonym)|uniprotkb:Dat1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7840003|mint:MINT-73286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021609(gene)|ensembl:ENSMUST00000022100(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|reactome:R-MMU-379401|reactome:R-MMU-442660|go:"GO:0045121"(membrane raft)|refseq:NP_034150.1|dip:DIP-41828N|mint:MINT-577108(identity) go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993|mint:MINT-577113(identity) - function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5A F5B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10090(mouse-midbrain neuro)|taxid:10090(Mus musculus) - 2005/12/13 2014/10/16 rogid:k3+G+CyceTOyUuiUJvry6NMrRNA10090 rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090 intact-crc:8B990EF8E63BB0BA|rigid:NRCn8CjvuDoXIJYFQnH6FB5pqjs false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q62083 uniprotkb:Q01959 intact:EBI-77550|uniprotkb:E9PY04 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:"MI:0428"(imaging technique) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7840170|mint:MINT-73294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993|mint:MINT-577100(identity) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N|mint:MINT-577091(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10090(mouse-midbrain neuro)|taxid:10090(Mus musculus) - 2005/12/13 2014/10/16 rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 intact-crc:3EB4D4416D5AF3AA|rigid:Xo3GC5lcWamrdCQ2GRBlnEax/CM false - ha tag:?-?(MINT-577094)|mutation decreasing interaction:617-620(MINT-577092) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q61327 uniprotkb:O88935 intact:EBI-7839708|ensembl:ENSMUSP00000022100|uniprotkb:Q60719|uniprotkb:Q9R1I2|intact:MINT-576974 intact:EBI-775644|uniprotkb:Q62279|uniprotkb:Q8QZT8|ensembl:ENSMUSP00000080568 psi-mi:sc6a3_mouse(display_long)|uniprotkb:Slc6a3(gene name)|psi-mi:Slc6a3(display_short)|uniprotkb:Dat(gene name synonym)|uniprotkb:Dat1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:syn1_mouse(display_long)|uniprotkb:Synapsin I(gene name synonym)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Syn-1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7840136|mint:MINT-73291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021609(gene)|ensembl:ENSMUST00000022100(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0010039"(response to iron ion)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|reactome:R-MMU-379401|reactome:R-MMU-442660|go:"GO:0045121"(membrane raft)|refseq:NP_034150.1|dip:DIP-41828N|mint:MINT-1600004(identity) refseq:NP_001104250.1|refseq:NP_038708.3|ensembl:ENSMUSG00000037217(gene)|ensembl:ENSMUST00000081893(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:O88935|reactome:R-MMU-181429|reactome:R-MMU-212676|mint:MINT-1600009(identity) - function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10090(mouse-midbrain neuro)|taxid:10090(Mus musculus) - 2005/12/13 2014/10/16 rogid:k3+G+CyceTOyUuiUJvry6NMrRNA10090 rogid:z48y84jWlS6gOiBDyvxI+aRYzdY10090 intact-crc:47F8E36564BF8057|rigid:Y4tvsoTAqN0x0tEm+D9fStfAAQE false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q9NRD5 uniprotkb:Q01959 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-6661445|ensembl:ENSP00000270349|ensembl:ENSP00000479597|uniprotkb:A2RUN4|uniprotkb:Q14996 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:sc6a3_human(display_long)|uniprotkb:SLC6A3(gene name)|psi-mi:SLC6A3(display_short)|uniprotkb:DAT1(gene name synonym)|uniprotkb:Solute carrier family 6 member 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7840247|mint:MINT-73279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993|mint:MINT-577210(identity) go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0007626"(locomotory behavior)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0016600"(flotillin complex)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030424"(axon)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051591"(response to cAMP)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002436("Sodium:neurotransmitter symporter, dopamine")|interpro:IPR037272|mint:Q01959|reactome:R-HSA-379401|reactome:R-HSA-442660|reactome:R-HSA-5619081|reactome:R-HSA-5660724|ensembl:ENSG00000142319(gene)|ensembl:ENSG00000276996(gene)|ensembl:ENST00000270349(transcript)|ensembl:ENST00000621716(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007608"(sensory perception of smell)|refseq:NP_001035.1|dip:DIP-41827N|mint:MINT-577198(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A F1B F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/12/13 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:mQKSGpeovNv4Sg8T2E3A8rVB2aY9606 intact-crc:C490893F6DAF6BFA|rigid:0SIIiOLPsOhmugHFUx8gmxonT/8 false mutation decreasing interaction:27-27,28-28(MINT-577211)|tag:?-?(MINT-577214) mutation decreasing interaction:617-620(MINT-577202)|tag:?-?(MINT-577204)|binding-associated region:578-620(MINT-577199) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23975 uniprotkb:Q9NRD5 intact:EBI-6661391|ensembl:ENSP00000369237|ensembl:ENSP00000457473|uniprotkb:B2R707|uniprotkb:Q96KH8|uniprotkb:B4DX48 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 psi-mi:sc6a2_human(display_long)|uniprotkb:SLC6A2(gene name)|psi-mi:SLC6A2(display_short)|uniprotkb:NAT1(gene name synonym)|uniprotkb:NET1(gene name synonym)|uniprotkb:SLC6A5(gene name synonym)|uniprotkb:Norepinephrine transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 2(gene name synonym) psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7840338|mint:MINT-73295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103546(gene)|ensembl:ENST00000379906(transcript)|ensembl:ENST00000568943(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005328"("neurotransmitter:sodium symporter activity")|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0015844"(monoamine transport)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051620"(norepinephrine uptake)|go:"GO:0070050"(neuron cellular homeostasis)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002435("Sodium:neurotransmitter symporter, noradrenaline")|interpro:IPR037272|reactome:R-HSA-442660|reactome:R-HSA-5619109|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035725"(sodium ion transmembrane transport)|refseq:XP_011521597.1|refseq:NP_001034.1|refseq:NP_001165972.1|refseq:NP_001165975.1|refseq:NP_001165973.1|refseq:XP_006721326.1|mint:MINT-577163(identity) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993|mint:MINT-577175(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/12/13 2014/10/16 rogid:hehF0DnHCYX/ZiRKE7nzQBciHyA9606 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 intact-crc:5849B41A1581AA2D|rigid:Sj2bRh7PTzWMIIlgcidnRYVg08I false tag:?-?(MINT-577169)|binding-associated region:575-617(MINT-577164)|mutation decreasing interaction:615-617(MINT-577167) tag:?-?(MINT-577176) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRD5 uniprotkb:P31645 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-6116107|uniprotkb:Q5EE02|ensembl:ENSP00000261707|ensembl:ENSP00000385822|ensembl:ENSP00000498537 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:sc6a4_human(display_long)|uniprotkb:SLC6A4(gene name)|psi-mi:SLC6A4(display_short)|uniprotkb:HTT(gene name synonym)|uniprotkb:SERT(gene name synonym)|uniprotkb:5HT transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7840397|mint:MINT-73296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993|mint:MINT-577153(identity) refseq:NP_001036.1|ensembl:ENSG00000108576(gene)|ensembl:ENST00000261707(transcript)|ensembl:ENST00000401766(transcript)|ensembl:ENST00000650711(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005335"("serotonin:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0015844"(monoamine transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019811"(cocaine binding)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0035176"(social behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042493"|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0051610"(serotonin uptake)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090067"(regulation of thalamus size)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099154"(serotonergic synapse)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR013086("Sodium:neurotransmitter symporter, serotonin, N-terminal")|interpro:IPR037272|rcsb pdb:5I6X|rcsb pdb:5I6Z|rcsb pdb:5I71|rcsb pdb:5I73|rcsb pdb:5I74|rcsb pdb:5I75|rcsb pdb:6AWN|rcsb pdb:6AWO|rcsb pdb:6AWP|rcsb pdb:6AWQ|rcsb pdb:6DZV|rcsb pdb:6DZW|rcsb pdb:6DZY|rcsb pdb:6DZZ|rcsb pdb:6VRH|rcsb pdb:6VRK|rcsb pdb:6VRL|rcsb pdb:6W2B|rcsb pdb:6W2C|reactome:R-HSA-380615|mint:MINT-577143(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/12/13 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:mZYK0YEOl23+K9N0+v10I6r/Y4o9606 intact-crc:AD72E8EAAB0AFAAA|rigid:rPH60IZsvONhUsgY+KVOS/epCgw false tag:?-?(MINT-577154) tag:?-?(MINT-577147)|binding-associated region:594-630(MINT-577144) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55192 uniprotkb:Q62083 intact:EBI-7840521|ensembl:ENSMUSP00000072709|ensembl:ENSMUSP00000129869|intact:MINT-1770608|uniprotkb:Q6QU62 intact:EBI-77550|uniprotkb:E9PY04 psi-mi:sc6a2_mouse(display_long)|uniprotkb:Slc6a2(gene name)|psi-mi:Slc6a2(display_short)|uniprotkb:Norepinephrine transporter(gene name synonym)|uniprotkb:Solute carrier family 6 member 2(gene name synonym) psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Torres et al. (2001) pubmed:11343649|mint:MINT-5214000 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7840516|mint:MINT-73300 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000055368(gene)|ensembl:ENSMUST00000072939(transcript)|ensembl:ENSMUST00000165470(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005328"("neurotransmitter:sodium symporter activity")|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0009986"(cell surface)|go:"GO:0015844"(monoamine transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051620"(norepinephrine uptake)|go:"GO:0098810"(neurotransmitter reuptake)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002435("Sodium:neurotransmitter symporter, noradrenaline")|interpro:IPR037272|reactome:R-MMU-442660|refseq:NP_033235.3|refseq:XP_006530856.1|refseq:XP_006530857.1|mint:MINT-1770620(identity) go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993|mint:MINT-1770625(identity) - comment:mint|function:Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10090(mouse-locus coeruleu)|taxid:10090(Mus musculus) - 2005/12/13 2014/10/16 rogid:6J7paWXSc+dcHJjRp/LgSLHNJ5k10090 rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090 intact-crc:FCC7E4E933976739|rigid:isoWh3cQ7ttfknEIx4oqj166d7E false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification)