#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O54874	uniprotkb:O54874	intact:EBI-689253	intact:EBI-689253	psi-mi:mrcka_rat(display_long)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:Cdc42bpa(gene name)|psi-mi:Cdc42bpa(display_short)|uniprotkb:Pk428(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_rat(display_long)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:Cdc42bpa(gene name)|psi-mi:Cdc42bpa(display_short)|uniprotkb:Pk428(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tan et al. (2001)	pubmed:11283256	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-689282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621406|refseq:NP_446109.1|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017892|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR031597|rcsb pdb:4AW2|interpro:IPR026611|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406	rgd:621406|refseq:NP_446109.1|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017892|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR031597|rcsb pdb:4AW2|interpro:IPR026611|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406	go:"GO:0042803"(protein homodimerization activity)	-	-	-	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2005/09/30	2014/10/16	rogid:oq31Mwavu9Tt7QfxaQYlPf8eS9Y10116	rogid:oq31Mwavu9Tt7QfxaQYlPf8eS9Y10116	intact-crc:317419DF00D0060F|rigid:MJK3cJNHJEZXUcCmL8/Gma/ZI/o	false	-	-	2	0	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:O54874	uniprotkb:O54874	intact:EBI-689253	intact:EBI-689253	psi-mi:mrcka_rat(display_long)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:Cdc42bpa(gene name)|psi-mi:Cdc42bpa(display_short)|uniprotkb:Pk428(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_rat(display_long)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:Cdc42bpa(gene name)|psi-mi:Cdc42bpa(display_short)|uniprotkb:Pk428(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tan et al. (2001)	pubmed:11283256	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-689286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621406|refseq:NP_446109.1|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017892|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR031597|rcsb pdb:4AW2|interpro:IPR026611|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406	rgd:621406|refseq:NP_446109.1|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017892|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR031597|rcsb pdb:4AW2|interpro:IPR026611|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406	go:"GO:0042802"(identical protein binding)	-	-	-	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2005/09/30	2014/10/16	rogid:oq31Mwavu9Tt7QfxaQYlPf8eS9Y10116	rogid:oq31Mwavu9Tt7QfxaQYlPf8eS9Y10116	intact-crc:300F3A9A203525AF|rigid:MJK3cJNHJEZXUcCmL8/Gma/ZI/o	false	-	-	4	0	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-689320	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0042802"(identical protein binding)	-	-	comment:Stoichiometry unknown but multiple	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/09/30	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:3D593B0F475A2D65|rigid:S805bT6u59oaEjK2Xv8VtyJheB4	false	flag tag:n-n	flag tag:n-n	-	0	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
intact:EBI-689328	intact:EBI-689328	-	-	psi-mi:mrcka(display_short)|psi-mi:EBI-689328(display_long)	psi-mi:mrcka(display_short)|psi-mi:EBI-689328(display_long)	psi-mi:"MI:0030"(cross-linking study)	Tan et al. (2001)	pubmed:11283256	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-689338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	-	go:"GO:0042802"(identical protein binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	no-uniprot-update:An amino acid sequence which is not represented in UniProt	comment:Stoichiometry unknown but multiple	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/09/30	2014/10/16	-	-	intact-crc:39220EDE2C4ADB42	false	-	-	-	0	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-691984	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0042802"(identical protein binding)	-	-	comment:Stoichiometry unknown but multiple	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/09/30	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:CD7F55586F5805C3|rigid:S805bT6u59oaEjK2Xv8VtyJheB4	false	binding-associated region:466-1018|flag tag:n-n	binding-associated region:466-1018|flag tag:n-n	2	0	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-692021	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0042803"(protein homodimerization activity)	-	-	comment:Molecular weight suggests product to be a homodimer	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/09/30	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:130EA9CB62B5F5DD|rigid:S805bT6u59oaEjK2Xv8VtyJheB4	false	flag tag:n-n|binding-associated region:1-473	flag tag:n-n|binding-associated region:1-473	2	0	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-689355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0042802"(identical protein binding)	-	-	-	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/09/30	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:F94F853339552C3E|rigid:CGRfSRzl/RFPsF2Wdyray8ARi/c	false	binding-associated region:466-1018|ha tag:n-n	flag tag:n-n|binding-associated region:466-1018	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-689394	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0042802"(identical protein binding)	-	-	-	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/09/30	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:14584E70B94B9DA5|rigid:CGRfSRzl/RFPsF2Wdyray8ARi/c	false	ha tag:n-n|binding-associated region:466-710|binding-associated region:710-854	flag tag:n-n|binding-associated region:466-710|binding-associated region:710-854	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-692004	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0042803"(protein homodimerization activity)	-	-	comment:Molecular weight suggests product to be a homodimer|comment:N-terminal homodimerization is required for enzyme autoactivation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/09/30	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:3C25BFC542D3F2BF|rigid:CGRfSRzl/RFPsF2Wdyray8ARi/c	false	binding-associated region:1-70|flag tag:n-n	binding-associated region:1-473|ha tag:n-n	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-692053	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0006469"(negative regulation of protein kinase activity)	-	-	comment:"Coiled-coil region will only interact with inactive kinase domain. This interaction prevents kinase domain from phosphorylating MRCL3 (MLC2)"	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/09/30	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:6CCFEB82652ED64D|rigid:CGRfSRzl/RFPsF2Wdyray8ARi/c	false	flag tag:n-n|binding-associated region:658-930	binding-associated region:70-473|flag tag:n-n	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P19105	uniprotkb:Q5VT25	intact:EBI-354418|uniprotkb:Q53X45|ensembl:ENSP00000217652|ensembl:ENSP00000441231|ensembl:ENSP00000462171|ensembl:ENSP00000463614	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:ml12a_human(display_long)|uniprotkb:MYL12A(gene name)|psi-mi:MYL12A(display_short)|uniprotkb:RLC(gene name synonym)|uniprotkb:MLCB(gene name synonym)|uniprotkb:Myosin regulatory light chain 2, nonsarcomeric(gene name synonym)|uniprotkb:Myosin RLC(gene name synonym)|uniprotkb:MLC-2B(gene name synonym)|uniprotkb:MRLC3(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC3(gene name synonym)|uniprotkb:Epididymis secretory protein Li 24(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-692039	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006462.1|refseq:NP_001289976.1|refseq:NP_001289977.1|refseq:NP_001289978.1|ensembl:ENSG00000101608(gene)|ensembl:ENST00000217652(transcript)|ensembl:ENST00000536605(transcript)|ensembl:ENST00000578611(transcript)|ensembl:ENST00000579226(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:P19105|reactome:R-HSA-3928664|reactome:R-HSA-445355	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	comment:Previous experiments have shown this construct of CDC42BPA to dimerize, and that this required for enzyme activity. A transphosphorylation event is required within the dimer for activation to occur.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/09/30	2014/10/16	rogid:Q1Uv36YgdA5rMmMOyX5+3rKKho09606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:43E0FDF40AA381CF|rigid:B25I5yoMhj4AtQuQURWcAacs1bk	false	glutathione s tranferase tag:?-?	ha tag:n-n|binding-associated region:1-473|mutation decreasing interaction:234-234|mutation decreasing interaction:106-106|mutation decreasing interaction:240-240|mutation decreasing interaction:403-403	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5VT25	uniprotkb:Q5VT25	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	intact:EBI-689171|ensembl:ENSP00000335341|intact:EBI-1383420|uniprotkb:Q59GZ1|uniprotkb:Q5H9N9|uniprotkb:Q5T797|uniprotkb:Q5VT26|uniprotkb:Q5VT27|uniprotkb:Q86XX2|uniprotkb:Q86XX3|uniprotkb:Q99646|uniprotkb:O75039	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:mrcka_human(display_long)|uniprotkb:CDC42BPA(gene name)|psi-mi:CDC42BPA(display_short)|uniprotkb:KIAA0451(gene name synonym)|uniprotkb:Myotonic dystrophy kinase-related CDC42-binding kinase alpha(gene name synonym)|uniprotkb:DMPK-like alpha(gene name synonym)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Tan et al. (2001)	pubmed:11283256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-696792	-	-	psi-mi:"MI:0503"(self)	psi-mi:"MI:0503"(self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|ensembl:ENSG00000143776(gene)|ensembl:ENST00000334218(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|refseq:NP_003598.2|refseq:NP_055641.3|refseq:XP_005273378.1|refseq:XP_005273379.1|refseq:XP_005273381.1	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	comment:Previous experiments have shown this construct of CDC42BPA to dimerize, and that this required for enzyme activity. A transphosphorylation event is required within the dimer for activation to occur.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/09/30	2014/10/16	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	rogid:UkgvBl+h8HZGHZBnI/7B6JM8kFY9606	intact-crc:804E5BC2DD9FBDA3|rigid:S805bT6u59oaEjK2Xv8VtyJheB4	false	binding-associated region:1-473(IPR000719)|mutation decreasing interaction:106-106|mutation decreasing interaction:234-234|mutation decreasing interaction:240-240|mutation decreasing interaction:403-403|ha tag:n-n	binding-associated region:1-473(IPR000719)|mutation decreasing interaction:106-106|mutation decreasing interaction:234-234|mutation decreasing interaction:240-240|mutation decreasing interaction:403-403|ha tag:n-n	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)