#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P28700 uniprotkb:P23246-1 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 intact:EBI-355463|ensembl:ENSP00000349748 psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:p23246-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564 intact:EBI-355453(sfpq_human)|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript) - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/05/26 2014/10/16 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 intact-crc:5D933BD5557AA75E|rigid:U43wm+YqshijEriPlfrtBxPHY5Q false binding-associated region:140-205|glutathione s tranferase tag:?-?|tag:?-? - - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:Q15233 uniprotkb:P28700 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564 - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/05/26 2014/10/16 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 intact-crc:9CFEA1BFAA951547|rigid:EJp7ee7LOUTaZvL/gBYL+f7OxMU false - binding-associated region:140-205|glutathione s tranferase tag:?-?|tag:?-? - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:P23246-1 uniprotkb:P28700 intact:EBI-355463|ensembl:ENSP00000349748 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:p23246-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591312 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-355453(sfpq_human)|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564 - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/05/26 2014/10/16 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 intact-crc:BC0ADF1B7D678ED6|rigid:U43wm+YqshijEriPlfrtBxPHY5Q false radiolabel:?-? glutathione s tranferase tag:?-?|tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04625 uniprotkb:P23246-1 intact:EBI-286261|ensembl:ENSGALP00000050455|ensembl:ENSGALP00000052375 intact:EBI-355463|ensembl:ENSP00000349748 psi-mi:tha_chick(display_long)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:NR1A1(gene name synonym) psi-mi:p23246-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_990644.1|dip:DIP-32625N|ensembl:ENSGALG00000040017(gene)|ensembl:ENSGALT00000052263(transcript)|ensembl:ENSGALT00000058539(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:3UVV intact:EBI-355453(sfpq_human)|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript) - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/05/26 2014/10/16 rogid:Q1X4sKTKPPwLgWkWtTphoDESXqk9031 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 intact-crc:07E489AD571D698F|rigid:TVm454BfD5BCSxRermkYEXwkWS8 false glutathione s tranferase tag:?-?|tag:?-? radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96ST3 uniprotkb:P23246 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591436 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/05/26 2014/10/16 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 intact-crc:BB7DAD93DE80918C|rigid:SppaD95mL/zUAKr67Jf3NzC2kow false binding-associated region:404-545|glutathione s tranferase tag:?-?|tag:?-? radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23246-1 uniprotkb:Q15233 intact:EBI-355463|ensembl:ENSP00000349748 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:p23246-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-355453(sfpq_human)|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript) refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/05/26 2014/10/16 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 intact-crc:B8626C2227C4172E|rigid:wyQQk0u7lncyT+zQRZLIAmYiz3Q false radiolabel:?-? glutathione s tranferase tag:?-?|tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y618 uniprotkb:P04625 intact:EBI-80830|uniprotkb:Q9Y5U0|uniprotkb:O00613|uniprotkb:O15416|uniprotkb:Q13354|uniprotkb:O15421|intact:EBI-28976851|uniprotkb:Q56D06|uniprotkb:Q59GM0|ensembl:ENSP00000384018 intact:EBI-286261|ensembl:ENSGALP00000050455|ensembl:ENSGALP00000052375 psi-mi:ncor2_human(display_long)|uniprotkb:NCOR2(gene name)|psi-mi:NCOR2(display_short)|uniprotkb:CTG26(gene name synonym)|uniprotkb:Silencing mediator of retinoic acid and thyroid hormone receptor(gene name synonym)|uniprotkb:Thyroid-, retinoic-acid-receptor-associated corepressor(gene name synonym)|uniprotkb:T3 receptor-associating factor(gene name synonym)|uniprotkb:CTG repeat protein 26(gene name synonym)|uniprotkb:SMAP270(gene name synonym) psi-mi:tha_chick(display_long)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:NR1A1(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591654 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000384018|refseq:NP_001070729.2|refseq:NP_001193583.1|refseq:NP_006303.4|dip:DIP-951N|ensembl:ENSG00000196498(gene)|ensembl:ENST00000405201(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007595"(lactation)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:Q9Y618|rcsb pdb:1KKQ|rcsb pdb:1R2B|rcsb pdb:1XC5|rcsb pdb:2GPV|rcsb pdb:2L5G|rcsb pdb:2LTP|rcsb pdb:2ODD|rcsb pdb:2RT5|rcsb pdb:3R29|rcsb pdb:3R2A|rcsb pdb:4A69|rcsb pdb:4OAR|rcsb pdb:5X8Q|rcsb pdb:5X8X|rcsb pdb:5ZOO|rcsb pdb:5ZOP|rcsb pdb:6A22|rcsb pdb:6IVX|rcsb pdb:6PDZ|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564 refseq:NP_990644.1|dip:DIP-32625N|ensembl:ENSGALG00000040017(gene)|ensembl:ENSGALT00000052263(transcript)|ensembl:ENSGALT00000058539(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:3UVV - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/05/26 2018/09/18 rogid:58SZfHIXN3dZN93fsiVHbbEwD0g9606 rogid:Q1X4sKTKPPwLgWkWtTphoDESXqk9031 intact-crc:30AB11E97EB6FE71|rigid:z0U0zZZzydMmP4VhH1VrRiFqHME false glutathione s tranferase tag:?-?|binding-associated region:1055-1495|tag:?-? radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23246-1 uniprotkb:P28700 intact:EBI-355463|ensembl:ENSP00000349748 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:p23246-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-355453(sfpq_human)|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564 - - - comment:Interaction is independent from receptor hormone ligand binding. taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2005/05/26 2014/10/16 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 intact-crc:5C34251FCC8D03D2|rigid:U43wm+YqshijEriPlfrtBxPHY5Q false - binding-associated region:140-239|glutathione s tranferase tag:?-?|tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P23246-1 uniprotkb:P04625 intact:EBI-355463|ensembl:ENSP00000349748 intact:EBI-286261|ensembl:ENSGALP00000050455|ensembl:ENSGALP00000052375 psi-mi:p23246-1(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym) psi-mi:tha_chick(display_long)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:NR1A1(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591416 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-355453(sfpq_human)|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript) refseq:NP_990644.1|dip:DIP-32625N|ensembl:ENSGALG00000040017(gene)|ensembl:ENSGALT00000052263(transcript)|ensembl:ENSGALT00000058539(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:3UVV - - - comment:Interaction is independent from receptor hormone ligand binding. taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2005/05/26 2014/10/16 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rogid:Q1X4sKTKPPwLgWkWtTphoDESXqk9031 intact-crc:B43167523C97F32E|rigid:TVm454BfD5BCSxRermkYEXwkWS8 false - binding-associated region:1-119|glutathione s tranferase tag:?-?|tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P23246 uniprotkb:Q96ST3 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591428 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N - - - - taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/05/26 2014/10/16 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 intact-crc:3E61DF8D3F886E13|rigid:SppaD95mL/zUAKr67Jf3NzC2kow false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28700 uniprotkb:Q96ST3 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564 refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N - - - - taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/05/26 2014/10/16 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 intact-crc:ABC59C866B5CE222|rigid:FjCNOjv7qXRv3JYQtCTfmtZDUPg false binding-associated region:140-239|glutathione s tranferase tag:?-?|tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96ST3 uniprotkb:P04625 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 intact:EBI-286261|ensembl:ENSGALP00000050455|ensembl:ENSGALP00000052375 psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:tha_chick(display_long)|uniprotkb:THRA(gene name)|psi-mi:THRA(display_short)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:NR1A1(gene name synonym) psi-mi:"MI:0096"(pull down) Mathur et al. (2001) pubmed:11259580 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-591615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N refseq:NP_990644.1|dip:DIP-32625N|ensembl:ENSGALG00000040017(gene)|ensembl:ENSGALT00000052263(transcript)|ensembl:ENSGALT00000058539(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:3UVV - - - - taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/05/26 2014/10/16 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 rogid:Q1X4sKTKPPwLgWkWtTphoDESXqk9031 intact-crc:0B5303CC35965CEB|rigid:gyJuh+BtbN/3eWF38Qs7NzxKpe0 false - binding-associated region:1-151|glutathione s tranferase tag:?-?|tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)