#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O65312	uniprotkb:Q9LT47	intact:EBI-632832|ensemblplants:AT1G02580.1	intact:EBI-307146|uniprotkb:Q9XF44|ensemblplants:AT3G20740.1	psi-mi:medea_arath(display_long)|uniprotkb:EMB173(gene name synonym)|uniprotkb:Maternal embryogenesis control protein(gene name synonym)|uniprotkb:Protein FERTILIZATION-INDEPENDENT SEED 1(gene name synonym)|uniprotkb:Protein SET DOMAIN GROUP 5(gene name synonym)|uniprotkb:Protein EMBRYO DEFECTIVE 173(gene name synonym)|uniprotkb:MEA(gene name)|psi-mi:MEA(display_short)|uniprotkb:FIS1(gene name synonym)|uniprotkb:At1g02580(locus name)|uniprotkb:T14P4.11(orf name)|uniprotkb:MEDEA(gene name synonym)|uniprotkb:SDG5(gene name synonym)|uniprotkb:SET5(gene name synonym)	psi-mi:fie_arath(display_long)|uniprotkb:FIE(gene name)|psi-mi:FIE(display_short)|uniprotkb:FIS3(gene name synonym)|uniprotkb:At3g20740(locus name)|uniprotkb:MOE17.5(orf name)|uniprotkb:Protein FERTILIZATION-INDEPENDENT SEED 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Spillane et al. (2000)	pubmed:11114524	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-632841	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_563658.1|interpro:IPR001214(SET)|ensemblplants:AT1G02580.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009646"(response to absence of light)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032259"(methylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048317"(seed morphogenesis)|go:"GO:2000014"(regulation of endosperm development)|ensemblplants:AT1G02580(gene)|interpro:IPR025778|interpro:IPR026489|interpro:IPR033467|interpro:IPR041355	refseq:NP_188710.1|ensemblplants:AT3G20740(gene)|ensemblplants:AT3G20740.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0009409"(response to cold)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0043078"(polar nucleus)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:2000014"(regulation of endosperm development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-31378N	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/08/12	2014/10/16	rogid:C9eW/b2wGlafih0wMf5WLmRon103702	rogid:y18IHci3+i/YUVU3md9LUjOJ0vA3702	intact-crc:F57EED13A94F62F1|rigid:a4bID6bPOoTqoPHSz/ElRx+dUe0	false	binding-associated region:4-109	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q24338	uniprotkb:P42124	intact:EBI-88911|ensemblmetazoa:FBpp0079907	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	psi-mi:esc_drome(display_long)|uniprotkb:esc(gene name)|psi-mi:esc(display_short)|uniprotkb:CG14941(orf name)|uniprotkb:Protein extra sex combs(gene name synonym)	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Spillane et al. (2000)	pubmed:11114524	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-632868	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0000588(gene)|ensemblmetazoa:FBtr0080325(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042802"(identical protein binding)|go:"GO:0048096"|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q24338|go:"GO:0016458"(obsolete gene silencing)|refseq:NP_477431.1|flybase:FBgn0000588|dip:DIP-20069N	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/08/12	2014/10/16	rogid:owOOCkwb0LdPVnElMax3J1OIkEE7227	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	intact-crc:9C7556BB93F491AE|rigid:97CWoQ2IMfsQ4bSxZAjIKwtv42U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q24338	uniprotkb:O65312	intact:EBI-88911|ensemblmetazoa:FBpp0079907	intact:EBI-632832|ensemblplants:AT1G02580.1	psi-mi:esc_drome(display_long)|uniprotkb:esc(gene name)|psi-mi:esc(display_short)|uniprotkb:CG14941(orf name)|uniprotkb:Protein extra sex combs(gene name synonym)	psi-mi:medea_arath(display_long)|uniprotkb:EMB173(gene name synonym)|uniprotkb:Maternal embryogenesis control protein(gene name synonym)|uniprotkb:Protein FERTILIZATION-INDEPENDENT SEED 1(gene name synonym)|uniprotkb:Protein SET DOMAIN GROUP 5(gene name synonym)|uniprotkb:Protein EMBRYO DEFECTIVE 173(gene name synonym)|uniprotkb:MEA(gene name)|psi-mi:MEA(display_short)|uniprotkb:FIS1(gene name synonym)|uniprotkb:At1g02580(locus name)|uniprotkb:T14P4.11(orf name)|uniprotkb:MEDEA(gene name synonym)|uniprotkb:SDG5(gene name synonym)|uniprotkb:SET5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Spillane et al. (2000)	pubmed:11114524	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-632871	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0000588(gene)|ensemblmetazoa:FBtr0080325(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042802"(identical protein binding)|go:"GO:0048096"|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q24338|go:"GO:0016458"(obsolete gene silencing)|refseq:NP_477431.1|flybase:FBgn0000588|dip:DIP-20069N	refseq:NP_563658.1|interpro:IPR001214(SET)|ensemblplants:AT1G02580.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009646"(response to absence of light)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032259"(methylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048317"(seed morphogenesis)|go:"GO:2000014"(regulation of endosperm development)|ensemblplants:AT1G02580(gene)|interpro:IPR025778|interpro:IPR026489|interpro:IPR033467|interpro:IPR041355	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/08/12	2014/10/16	rogid:owOOCkwb0LdPVnElMax3J1OIkEE7227	rogid:C9eW/b2wGlafih0wMf5WLmRon103702	intact-crc:B23328CB45A9AC37|rigid:Y5wIUWXYQkmIr8XzLBPiPcty490	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9LT47	uniprotkb:O65312	intact:EBI-307146|uniprotkb:Q9XF44|ensemblplants:AT3G20740.1	intact:EBI-632832|ensemblplants:AT1G02580.1	psi-mi:fie_arath(display_long)|uniprotkb:FIE(gene name)|psi-mi:FIE(display_short)|uniprotkb:FIS3(gene name synonym)|uniprotkb:At3g20740(locus name)|uniprotkb:MOE17.5(orf name)|uniprotkb:Protein FERTILIZATION-INDEPENDENT SEED 3(gene name synonym)	psi-mi:medea_arath(display_long)|uniprotkb:EMB173(gene name synonym)|uniprotkb:Maternal embryogenesis control protein(gene name synonym)|uniprotkb:Protein FERTILIZATION-INDEPENDENT SEED 1(gene name synonym)|uniprotkb:Protein SET DOMAIN GROUP 5(gene name synonym)|uniprotkb:Protein EMBRYO DEFECTIVE 173(gene name synonym)|uniprotkb:MEA(gene name)|psi-mi:MEA(display_short)|uniprotkb:FIS1(gene name synonym)|uniprotkb:At1g02580(locus name)|uniprotkb:T14P4.11(orf name)|uniprotkb:MEDEA(gene name synonym)|uniprotkb:SDG5(gene name synonym)|uniprotkb:SET5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Spillane et al. (2000)	pubmed:11114524	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-632875	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_188710.1|ensemblplants:AT3G20740(gene)|ensemblplants:AT3G20740.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0009409"(response to cold)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0043078"(polar nucleus)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:2000014"(regulation of endosperm development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-31378N	refseq:NP_563658.1|interpro:IPR001214(SET)|ensemblplants:AT1G02580.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009646"(response to absence of light)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032259"(methylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048317"(seed morphogenesis)|go:"GO:2000014"(regulation of endosperm development)|ensemblplants:AT1G02580(gene)|interpro:IPR025778|interpro:IPR026489|interpro:IPR033467|interpro:IPR041355	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/08/12	2014/10/16	rogid:y18IHci3+i/YUVU3md9LUjOJ0vA3702	rogid:C9eW/b2wGlafih0wMf5WLmRon103702	intact-crc:1A0A6199AD4119E7|rigid:a4bID6bPOoTqoPHSz/ElRx+dUe0	false	-	binding-associated region:4-109	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O65312	uniprotkb:Q9LT47	intact:EBI-632832|ensemblplants:AT1G02580.1	intact:EBI-307146|uniprotkb:Q9XF44|ensemblplants:AT3G20740.1	psi-mi:medea_arath(display_long)|uniprotkb:EMB173(gene name synonym)|uniprotkb:Maternal embryogenesis control protein(gene name synonym)|uniprotkb:Protein FERTILIZATION-INDEPENDENT SEED 1(gene name synonym)|uniprotkb:Protein SET DOMAIN GROUP 5(gene name synonym)|uniprotkb:Protein EMBRYO DEFECTIVE 173(gene name synonym)|uniprotkb:MEA(gene name)|psi-mi:MEA(display_short)|uniprotkb:FIS1(gene name synonym)|uniprotkb:At1g02580(locus name)|uniprotkb:T14P4.11(orf name)|uniprotkb:MEDEA(gene name synonym)|uniprotkb:SDG5(gene name synonym)|uniprotkb:SET5(gene name synonym)	psi-mi:fie_arath(display_long)|uniprotkb:FIE(gene name)|psi-mi:FIE(display_short)|uniprotkb:FIS3(gene name synonym)|uniprotkb:At3g20740(locus name)|uniprotkb:MOE17.5(orf name)|uniprotkb:Protein FERTILIZATION-INDEPENDENT SEED 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Spillane et al. (2000)	pubmed:11114524	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-632853	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_563658.1|interpro:IPR001214(SET)|ensemblplants:AT1G02580.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009646"(response to absence of light)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032259"(methylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048317"(seed morphogenesis)|go:"GO:2000014"(regulation of endosperm development)|ensemblplants:AT1G02580(gene)|interpro:IPR025778|interpro:IPR026489|interpro:IPR033467|interpro:IPR041355	refseq:NP_188710.1|ensemblplants:AT3G20740(gene)|ensemblplants:AT3G20740.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0009409"(response to cold)|go:"GO:0016571"(histone methylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0043078"(polar nucleus)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:2000014"(regulation of endosperm development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-31378N	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/08/12	2014/10/16	rogid:C9eW/b2wGlafih0wMf5WLmRon103702	rogid:y18IHci3+i/YUVU3md9LUjOJ0vA3702	intact-crc:BBB6E829E61D63B7|rigid:a4bID6bPOoTqoPHSz/ElRx+dUe0	false	glutathione s tranferase tag:?-?	tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)