#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35400	uniprotkb:Q9EP80	intact:EBI-6936416|intact:MINT-146474	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm7_rat(display_long)|uniprotkb:Grm7(gene name)|psi-mi:Grm7(display_short)|uniprotkb:Gprc1g(gene name synonym)|uniprotkb:Mglur7(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405112|mint:MINT-72973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007196"(adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0014050"(negative regulation of glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050877"(nervous system process)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061564"(axon development)|go:"GO:0070085"(glycosylation)|go:"GO:0070905"(serine binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR001883(GPCR, family 3, metabotropic glutamate receptor 7)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|rcsb pdb:2E4Z|reactome:R-RNO-418594|reactome:R-RNO-420499|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001642"(group III metabotropic glutamate receptor activity)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|refseq:NP_112302.1|rgd:619857|mint:P35400|dip:DIP-41145N|mint:MINT-431965(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-431975(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/02	2014/10/16	rogid:4p27GEshqsLLsQueJLDdVAXV6BY10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:CB8A24252E073150|rigid:zPFqlGL0b9WIV2DgtxkbJZ1t5sg	false	glutathione s tranferase tag:?-?(MINT-431969)|binding-associated region:850-915(MINT-431966)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P35400	uniprotkb:Q9EP80	intact:EBI-6936416|intact:MINT-146474	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm7_rat(display_long)|uniprotkb:Grm7(gene name)|psi-mi:Grm7(display_short)|uniprotkb:Gprc1g(gene name synonym)|uniprotkb:Mglur7(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405088|mint:MINT-72972	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007196"(adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0014050"(negative regulation of glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050877"(nervous system process)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061564"(axon development)|go:"GO:0070085"(glycosylation)|go:"GO:0070905"(serine binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR001883(GPCR, family 3, metabotropic glutamate receptor 7)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|rcsb pdb:2E4Z|reactome:R-RNO-418594|reactome:R-RNO-420499|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001642"(group III metabotropic glutamate receptor activity)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|refseq:NP_112302.1|rgd:619857|mint:P35400|dip:DIP-41145N|mint:MINT-431943(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-431953(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/02	2014/10/16	rogid:4p27GEshqsLLsQueJLDdVAXV6BY10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:669E1D5A0401788E|rigid:zPFqlGL0b9WIV2DgtxkbJZ1t5sg	false	binding-associated region:850-915(MINT-431944)|glutathione s tranferase tag:?-?(MINT-431947)	mutation decreasing interaction:27-27(MINT-431954)|flag tag:?-?(MINT-431956)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P31421	uniprotkb:Q9EP80	intact:EBI-7090147|ensembl:ENSRNOP00000017607|intact:MINT-146442	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm2_rat(display_long)|uniprotkb:Grm2(gene name)|psi-mi:Grm2(display_short)|uniprotkb:Gprc1b(gene name synonym)|uniprotkb:Mglur2(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405163|mint:MINT-72975	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000013171(gene)|ensembl:ENSRNOT00000017607(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001641"(group II metabotropic glutamate receptor activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010467"(gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014048"(regulation of glutamate secretion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090461"(glutamate homeostasis)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001458(GPCR, family 3, metabotropic glutamate receptor 2)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|mint:P31421|reactome:R-RNO-418594|reactome:R-RNO-420499|refseq:XP_017450945.1|refseq:XP_017450946.1|refseq:NP_001099181.1|rgd:2743|dip:DIP-41937N|mint:MINT-431924(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-431931(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/02	2014/10/16	rogid:LVjjD/Uvv4io40UWVuFTCMetoxw10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:726D19F7A57BFE04|rigid:xZAaI8FyBv1JxeHq5HvhLSqd/Ro	false	glutathione s tranferase tag:?-?(MINT-431925)	flag tag:?-?(MINT-431934)|mutation decreasing interaction:27-27(MINT-431932)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P31421	uniprotkb:Q9EP80	intact:EBI-7090147|ensembl:ENSRNOP00000017607|intact:MINT-146442	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm2_rat(display_long)|uniprotkb:Grm2(gene name)|psi-mi:Grm2(display_short)|uniprotkb:Gprc1b(gene name synonym)|uniprotkb:Mglur2(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405149|mint:MINT-72974	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000013171(gene)|ensembl:ENSRNOT00000017607(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001641"(group II metabotropic glutamate receptor activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010467"(gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014048"(regulation of glutamate secretion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090461"(glutamate homeostasis)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001458(GPCR, family 3, metabotropic glutamate receptor 2)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|mint:P31421|reactome:R-RNO-418594|reactome:R-RNO-420499|refseq:XP_017450945.1|refseq:XP_017450946.1|refseq:NP_001099181.1|rgd:2743|dip:DIP-41937N|mint:MINT-432099(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-432106(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/02	2014/10/16	rogid:LVjjD/Uvv4io40UWVuFTCMetoxw10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:DBBA168AF8EC52D0|rigid:xZAaI8FyBv1JxeHq5HvhLSqd/Ro	false	glutathione s tranferase tag:?-?(MINT-432100)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P35400	uniprotkb:Q9EP80	intact:EBI-6936416|intact:MINT-146474	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm7_rat(display_long)|uniprotkb:Grm7(gene name)|psi-mi:Grm7(display_short)|uniprotkb:Gprc1g(gene name synonym)|uniprotkb:Mglur7(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405190|mint:MINT-72981	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007196"(adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0014050"(negative regulation of glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050877"(nervous system process)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061564"(axon development)|go:"GO:0070085"(glycosylation)|go:"GO:0070905"(serine binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR001883(GPCR, family 3, metabotropic glutamate receptor 7)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|rcsb pdb:2E4Z|reactome:R-RNO-418594|reactome:R-RNO-420499|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001642"(group III metabotropic glutamate receptor activity)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|refseq:NP_112302.1|rgd:619857|mint:P35400|dip:DIP-41145N|mint:MINT-431985(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-431990(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:mint	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2005/12/02	2014/10/16	rogid:4p27GEshqsLLsQueJLDdVAXV6BY10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:3845BE6C8D3FA81D|rigid:zPFqlGL0b9WIV2DgtxkbJZ1t5sg	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P35400	uniprotkb:Q9EP80	intact:EBI-6936416|intact:MINT-146474	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm7_rat(display_long)|uniprotkb:Grm7(gene name)|psi-mi:Grm7(display_short)|uniprotkb:Gprc1g(gene name synonym)|uniprotkb:Mglur7(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405200|mint:MINT-72982	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007196"(adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0014050"(negative regulation of glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050877"(nervous system process)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061564"(axon development)|go:"GO:0070085"(glycosylation)|go:"GO:0070905"(serine binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR001883(GPCR, family 3, metabotropic glutamate receptor 7)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|rcsb pdb:2E4Z|reactome:R-RNO-418594|reactome:R-RNO-420499|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001642"(group III metabotropic glutamate receptor activity)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|refseq:NP_112302.1|rgd:619857|mint:P35400|dip:DIP-41145N|mint:MINT-431998(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-432003(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:mint	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2005/12/02	2014/10/16	rogid:4p27GEshqsLLsQueJLDdVAXV6BY10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:C2557C1D07683719|rigid:zPFqlGL0b9WIV2DgtxkbJZ1t5sg	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P35400	uniprotkb:Q9EP80	intact:EBI-6936416|intact:MINT-146474	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm7_rat(display_long)|uniprotkb:Grm7(gene name)|psi-mi:Grm7(display_short)|uniprotkb:Gprc1g(gene name synonym)|uniprotkb:Mglur7(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405216|mint:MINT-72969	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007196"(adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0014050"(negative regulation of glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050877"(nervous system process)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061564"(axon development)|go:"GO:0070085"(glycosylation)|go:"GO:0070905"(serine binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR001883(GPCR, family 3, metabotropic glutamate receptor 7)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|rcsb pdb:2E4Z|reactome:R-RNO-418594|reactome:R-RNO-420499|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001642"(group III metabotropic glutamate receptor activity)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|refseq:NP_112302.1|rgd:619857|mint:P35400|dip:DIP-41145N|mint:MINT-432039(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-432053(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/12/02	2014/10/16	rogid:4p27GEshqsLLsQueJLDdVAXV6BY10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:24322655BB8FA927|rigid:zPFqlGL0b9WIV2DgtxkbJZ1t5sg	false	binding-associated region:900-915(MINT-432040)|mutation decreasing interaction:915-915,913-913,914-914(MINT-432043)|tag:?-?(MINT-432047)	tag:?-?(MINT-432054)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35400	uniprotkb:Q9EP80	intact:EBI-6936416|intact:MINT-146474	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm7_rat(display_long)|uniprotkb:Grm7(gene name)|psi-mi:Grm7(display_short)|uniprotkb:Gprc1g(gene name synonym)|uniprotkb:Mglur7(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405264|mint:MINT-72971	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007196"(adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0014050"(negative regulation of glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050877"(nervous system process)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061564"(axon development)|go:"GO:0070085"(glycosylation)|go:"GO:0070905"(serine binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR001883(GPCR, family 3, metabotropic glutamate receptor 7)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|rcsb pdb:2E4Z|reactome:R-RNO-418594|reactome:R-RNO-420499|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001642"(group III metabotropic glutamate receptor activity)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|refseq:NP_112302.1|rgd:619857|mint:P35400|dip:DIP-41145N|mint:MINT-432013(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-432023(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1B|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/12/02	2014/10/16	rogid:4p27GEshqsLLsQueJLDdVAXV6BY10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:954796B25A571CD6|rigid:zPFqlGL0b9WIV2DgtxkbJZ1t5sg	false	binding-associated region:850-915(MINT-432014)|tag:?-?(MINT-432017)	tag:?-?(MINT-432030)|binding-associated region:13-358(MINT-432024)|mutation decreasing interaction:28-28,27-27(MINT-432027)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35400	uniprotkb:Q9EP80	intact:EBI-6936416|intact:MINT-146474	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:grm7_rat(display_long)|uniprotkb:Grm7(gene name)|psi-mi:Grm7(display_short)|uniprotkb:Gprc1g(gene name synonym)|uniprotkb:Mglur7(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405317|mint:MINT-72977	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007196"(adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0014050"(negative regulation of glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050877"(nervous system process)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061564"(axon development)|go:"GO:0070085"(glycosylation)|go:"GO:0070905"(serine binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR001883(GPCR, family 3, metabotropic glutamate receptor 7)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|rcsb pdb:2E4Z|reactome:R-RNO-418594|reactome:R-RNO-420499|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001642"(group III metabotropic glutamate receptor activity)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|refseq:NP_112302.1|rgd:619857|mint:P35400|dip:DIP-41145N|mint:MINT-432114(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-432124(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3A|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/12/02	2014/10/16	rogid:4p27GEshqsLLsQueJLDdVAXV6BY10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:9E3F668A71B21780|rigid:zPFqlGL0b9WIV2DgtxkbJZ1t5sg	false	binding-associated region:850-915(MINT-432115)|flag tag:?-?(MINT-432118)	tag:?-?(MINT-432125)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35400	uniprotkb:P05696	intact:EBI-6936416|intact:MINT-146474	intact:EBI-935801	psi-mi:grm7_rat(display_long)|uniprotkb:Grm7(gene name)|psi-mi:Grm7(display_short)|uniprotkb:Gprc1g(gene name synonym)|uniprotkb:Mglur7(gene name synonym)	psi-mi:kpca_rat(display_long)|uniprotkb:Prkca(gene name)|psi-mi:Prkca(display_short)|uniprotkb:Pkca(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405354|mint:MINT-72985	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007196"(adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010855"(adenylate cyclase inhibitor activity)|go:"GO:0014050"(negative regulation of glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050877"(nervous system process)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061564"(axon development)|go:"GO:0070085"(glycosylation)|go:"GO:0070905"(serine binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR001883(GPCR, family 3, metabotropic glutamate receptor 7)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|rcsb pdb:2E4Z|reactome:R-RNO-418594|reactome:R-RNO-420499|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001642"(group III metabotropic glutamate receptor activity)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|refseq:NP_112302.1|rgd:619857|mint:P35400|dip:DIP-41145N|mint:MINT-432072(identity)	interpro:IPR017892|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rgd:3395|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR020454|interpro:IPR011009(Protein kinase-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034663|mint:P05696|interpro:IPR035892|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002159"(desmosome assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035403"("histone kinase activity (H3-T6 specific)")|go:"GO:0035408"(histone H3-T6 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045471"(response to ethanol)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047484"(regulation of response to osmotic stress)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000707"(positive regulation of dense core granule biogenesis)|rcsb pdb:1DSY|rcsb pdb:2NCE|rcsb pdb:3GPE|rcsb pdb:3RDJ|rcsb pdb:3TWY|rcsb pdb:4L1L|rcsb pdb:5W4S|reactome:R-RNO-111933|reactome:R-RNO-114516|reactome:R-RNO-1250196|reactome:R-RNO-1433557|reactome:R-RNO-1433559|reactome:R-RNO-2179392|reactome:R-RNO-3000170|reactome:R-RNO-399997|reactome:R-RNO-416993|reactome:R-RNO-4419969|reactome:R-RNO-450520|reactome:R-RNO-5099900|reactome:R-RNO-5218921|reactome:R-RNO-5668599|reactome:R-RNO-76005|reactome:R-RNO-8853659|mint:MINT-432065(identity)	-	function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/12/02	2014/10/16	rogid:4p27GEshqsLLsQueJLDdVAXV6BY10116	rogid:wWfVnOun9EFrE7DtrG8RRwPIpLs10116	intact-crc:AC1C74F049D15053|rigid:/KbR0ldreaPyKAyEdhb17KqE4YI	false	flag tag:?-?(MINT-432073)	ha tag:?-?(MINT-432066)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05696	uniprotkb:Q9EP80	intact:EBI-935801	intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1	psi-mi:kpca_rat(display_long)|uniprotkb:Prkca(gene name)|psi-mi:Prkca(display_short)|uniprotkb:Pkca(gene name synonym)	psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dev et al. (2000)	pubmed:11007882|mint:MINT-5213031	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7405337|mint:MINT-72983	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR017892|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rgd:3395|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR020454|interpro:IPR011009(Protein kinase-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034663|mint:P05696|interpro:IPR035892|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002159"(desmosome assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035403"("histone kinase activity (H3-T6 specific)")|go:"GO:0035408"(histone H3-T6 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045471"(response to ethanol)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047484"(regulation of response to osmotic stress)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000707"(positive regulation of dense core granule biogenesis)|rcsb pdb:1DSY|rcsb pdb:2NCE|rcsb pdb:3GPE|rcsb pdb:3RDJ|rcsb pdb:3TWY|rcsb pdb:4L1L|rcsb pdb:5W4S|reactome:R-RNO-111933|reactome:R-RNO-114516|reactome:R-RNO-1250196|reactome:R-RNO-1433557|reactome:R-RNO-1433559|reactome:R-RNO-2179392|reactome:R-RNO-3000170|reactome:R-RNO-399997|reactome:R-RNO-416993|reactome:R-RNO-4419969|reactome:R-RNO-450520|reactome:R-RNO-5099900|reactome:R-RNO-5218921|reactome:R-RNO-5668599|reactome:R-RNO-76005|reactome:R-RNO-8853659|mint:MINT-432082(identity)	rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N|mint:MINT-432089(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5|comment:homomint|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/12/02	2014/10/16	rogid:wWfVnOun9EFrE7DtrG8RRwPIpLs10116	rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116	intact-crc:119C1A471E365106|rigid:24c6RWJBPoKV1SQtSUJ4pYcsw3w	false	ha tag:?-?(MINT-432083)	flag tag:?-?(MINT-432090)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)