#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P89079 uniprotkb:O55164 intact:EBI-7401124|intact:MINT-431542 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 psi-mi:e4or1_ade09(display_long)|uniprotkb:E4(gene name)|psi-mi:E4(display_short)|uniprotkb:Probable dUTPase E4 ORF1(gene name synonym)|uniprotkb:Early E4 14.0 kDa protein(gene name synonym)|uniprotkb:ORF1(gene name synonym) psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10527(hadv-9)|taxid:10527(Human adenovirus D serotype 9) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401087|mint:MINT-69627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P89079|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR029054|interpro:IPR036157|dip:DIP-44835N|mint:MINT-431705(identity) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431710(identity) - comment:mint|comment:homomint|function:Plays a key role in virus oncogenecity in animals. Binds and sequesters human MUPP1/MPDZ protein in the cytoplasm, preventing it from playing a role in cellular proliferation regulation. Induces cell transformation, probably by inactivating MPDZ protein|comment:"Stoichiometry: 1.0" comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" figure legend:F4A F5C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2005/11/17 2014/10/16 rogid:NtuDlTWsr1MWfNM4ARULmS3kn/U10527 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 intact-crc:2BBC5675C5BB831F|rigid:mjNEmIL+76/C+qwwEtrxUXhy6l0 false - binding-associated region:1105-1312(MINT-431711)|ha tag:?-?(MINT-431714) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P89079 uniprotkb:O55164 intact:EBI-7401124|intact:MINT-431542 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 psi-mi:e4or1_ade09(display_long)|uniprotkb:E4(gene name)|psi-mi:E4(display_short)|uniprotkb:Probable dUTPase E4 ORF1(gene name synonym)|uniprotkb:Early E4 14.0 kDa protein(gene name synonym)|uniprotkb:ORF1(gene name synonym) psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10527(hadv-9)|taxid:10527(Human adenovirus D serotype 9) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401175|mint:MINT-69629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P89079|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR029054|interpro:IPR036157|dip:DIP-44835N|mint:MINT-431545(identity) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431550(identity) - comment:mint|comment:homomint|function:Plays a key role in virus oncogenecity in animals. Binds and sequesters human MUPP1/MPDZ protein in the cytoplasm, preventing it from playing a role in cellular proliferation regulation. Induces cell transformation, probably by inactivating MPDZ protein|comment:"Stoichiometry: 1.0" comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" figure legend:F4A F5C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2005/11/17 2014/10/16 rogid:NtuDlTWsr1MWfNM4ARULmS3kn/U10527 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 intact-crc:32BF304854D4B26B|rigid:mjNEmIL+76/C+qwwEtrxUXhy6l0 false - ha tag:?-?(MINT-431554)|binding-associated region:1606-1706(MINT-431551) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P89079 uniprotkb:O55164 intact:EBI-7401124|intact:MINT-431542 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 psi-mi:e4or1_ade09(display_long)|uniprotkb:E4(gene name)|psi-mi:E4(display_short)|uniprotkb:Probable dUTPase E4 ORF1(gene name synonym)|uniprotkb:Early E4 14.0 kDa protein(gene name synonym)|uniprotkb:ORF1(gene name synonym) psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:"MI:0049"(filter binding) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10527(hadv-9)|taxid:10527(Human adenovirus D serotype 9) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7401204|mint:MINT-69630 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P89079|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR029054|interpro:IPR036157|dip:DIP-44835N|mint:MINT-431565(identity) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431570(identity) - comment:mint|comment:homomint|function:Plays a key role in virus oncogenecity in animals. Binds and sequesters human MUPP1/MPDZ protein in the cytoplasm, preventing it from playing a role in cellular proliferation regulation. Induces cell transformation, probably by inactivating MPDZ protein|comment:"Stoichiometry: 1.0" comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" figure legend:F5B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/17 2014/10/16 rogid:NtuDlTWsr1MWfNM4ARULmS3kn/U10527 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 intact-crc:325D553D277C41FF|rigid:mjNEmIL+76/C+qwwEtrxUXhy6l0 false - binding-associated region:1606-1706(MINT-431571)|glutathione s tranferase tag:?-?(MINT-431574) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55164 uniprotkb:P89079 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 intact:EBI-7401124|intact:MINT-431542 psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:e4or1_ade09(display_long)|uniprotkb:E4(gene name)|psi-mi:E4(display_short)|uniprotkb:Probable dUTPase E4 ORF1(gene name synonym)|uniprotkb:Early E4 14.0 kDa protein(gene name synonym)|uniprotkb:ORF1(gene name synonym) psi-mi:"MI:0049"(filter binding) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10527(hadv-9)|taxid:10527(Human adenovirus D serotype 9) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7401224|mint:MINT-69631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431748(identity) mint:P89079|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR029054|interpro:IPR036157|dip:DIP-44835N|mint:MINT-431743(identity) - comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" comment:mint|comment:homomint|function:Plays a key role in virus oncogenecity in animals. Binds and sequesters human MUPP1/MPDZ protein in the cytoplasm, preventing it from playing a role in cellular proliferation regulation. Induces cell transformation, probably by inactivating MPDZ protein|comment:"Stoichiometry: 1.0" figure legend:F5B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/17 2014/10/16 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 rogid:NtuDlTWsr1MWfNM4ARULmS3kn/U10527 intact-crc:4026D058B1AD610A|rigid:mjNEmIL+76/C+qwwEtrxUXhy6l0 false binding-associated region:1105-1312(MINT-431749)|glutathione s tranferase tag:?-?(MINT-431752) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P89079 uniprotkb:O55164 intact:EBI-7401124|intact:MINT-431542 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 psi-mi:e4or1_ade09(display_long)|uniprotkb:E4(gene name)|psi-mi:E4(display_short)|uniprotkb:Probable dUTPase E4 ORF1(gene name synonym)|uniprotkb:Early E4 14.0 kDa protein(gene name synonym)|uniprotkb:ORF1(gene name synonym) psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10527(hadv-9)|taxid:10527(Human adenovirus D serotype 9) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401312|mint:MINT-69624 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P89079|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR029054|interpro:IPR036157|dip:DIP-44835N|mint:MINT-431633(identity) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431640(identity) - comment:mint|comment:homomint|function:Plays a key role in virus oncogenecity in animals. Binds and sequesters human MUPP1/MPDZ protein in the cytoplasm, preventing it from playing a role in cellular proliferation regulation. Induces cell transformation, probably by inactivating MPDZ protein|comment:"Stoichiometry: 1.0" comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/17 2014/10/16 rogid:NtuDlTWsr1MWfNM4ARULmS3kn/U10527 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 intact-crc:931E17ED37AFAE25|rigid:mjNEmIL+76/C+qwwEtrxUXhy6l0 false glutathione s tranferase tag:?-?(MINT-431634) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:O55164 uniprotkb:P89079 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 intact:EBI-7401124|intact:MINT-431542 psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:e4or1_ade09(display_long)|uniprotkb:E4(gene name)|psi-mi:E4(display_short)|uniprotkb:Probable dUTPase E4 ORF1(gene name synonym)|uniprotkb:Early E4 14.0 kDa protein(gene name synonym)|uniprotkb:ORF1(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10527(hadv-9)|taxid:10527(Human adenovirus D serotype 9) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401288|mint:MINT-69623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431695(identity) mint:P89079|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR029054|interpro:IPR036157|dip:DIP-44835N|mint:MINT-431685(identity) - comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" comment:mint|comment:homomint|function:Plays a key role in virus oncogenecity in animals. Binds and sequesters human MUPP1/MPDZ protein in the cytoplasm, preventing it from playing a role in cellular proliferation regulation. Induces cell transformation, probably by inactivating MPDZ protein|comment:"Stoichiometry: 1.0" figure legend:F3 T1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/17 2014/10/16 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 rogid:NtuDlTWsr1MWfNM4ARULmS3kn/U10527 intact-crc:8A9F955ABB2EDB44|rigid:mjNEmIL+76/C+qwwEtrxUXhy6l0 false ha tag:?-?(MINT-431696) glutathione s tranferase tag:?-?(MINT-431689)|mutation decreasing interaction:122-122,123-123(MINT-431686) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36709 uniprotkb:O55164 intact:EBI-7401351|intact:MINT-146144 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 psi-mi:e413_ade12(display_long) psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:28282(ade12)|taxid:28282("Human adenovirus A serotype 12 (HAdV-12)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401344|mint:MINT-69626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040935.1|go:"GO:0039593"(suppression by virus of host exit from mitosis)|interpro:IPR008680(Mastadenovirus early E4 13 kDa)|dip:DIP-41950N|mint:MINT-431601(identity) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431608(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/17 2014/10/16 rogid:omXyf2NP9Ds6qvb171OfqRynBwc28282 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 intact-crc:D3BA2E15B72983BB|rigid:Hq8vGdUkNlQ7J65+atItgA91Sw0 false glutathione s tranferase tag:?-?(MINT-431602) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:O55164 uniprotkb:P04489 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 intact:EBI-6398911 psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:e411_ade05(display_long) psi-mi:"MI:0096"(pull down) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401328|mint:MINT-69625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431624(identity) go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N|mint:MINT-431617(identity) - comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/17 2014/10/16 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285 intact-crc:D326A6B9527CCC18|rigid:zQ9F/8jojEPi0kkhWNYkWtT5oy4 false - glutathione s tranferase tag:?-?(MINT-431618) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55164 uniprotkb:P06463 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 intact:EBI-1186926 psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:0096"(pull down) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401411|mint:MINT-69636 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431592(identity) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N|mint:MINT-431585(identity) - comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/17 2014/10/16 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 intact-crc:18F39A79F6BA1450|rigid:CN2eGL7YLGY3xrBS0wqgLsznXLE false - glutathione s tranferase tag:?-?(MINT-431586) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55164 uniprotkb:P06463 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 intact:EBI-1186926 psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short) psi-mi:"MI:0096"(pull down) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401369|mint:MINT-69635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431658(identity) refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N|mint:MINT-431649(identity) - comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/17 2014/10/16 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761 intact-crc:57EB25EECB457151|rigid:CN2eGL7YLGY3xrBS0wqgLsznXLE false ha tag:?-?(MINT-431659) mutation decreasing interaction:158-158(MINT-431650)|glutathione s tranferase tag:?-?(MINT-431652) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P89079 uniprotkb:O55164 intact:EBI-7401124|intact:MINT-431542 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 psi-mi:e4or1_ade09(display_long)|uniprotkb:E4(gene name)|psi-mi:E4(display_short)|uniprotkb:Probable dUTPase E4 ORF1(gene name synonym)|uniprotkb:Early E4 14.0 kDa protein(gene name synonym)|uniprotkb:ORF1(gene name synonym) psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10527(hadv-9)|taxid:10527(Human adenovirus D serotype 9) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7401451|mint:MINT-69628 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P89079|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR029054|interpro:IPR036157|dip:DIP-44835N|mint:MINT-431672(identity) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431677(identity) - comment:mint|comment:homomint|function:Plays a key role in virus oncogenecity in animals. Binds and sequesters human MUPP1/MPDZ protein in the cytoplasm, preventing it from playing a role in cellular proliferation regulation. Induces cell transformation, probably by inactivating MPDZ protein|comment:"Stoichiometry: 1.0" comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10116(rat-cref)|taxid:10116(Rattus norvegicus) - 2005/11/17 2014/10/16 rogid:NtuDlTWsr1MWfNM4ARULmS3kn/U10527 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 intact-crc:BD250B59607D1662|rigid:mjNEmIL+76/C+qwwEtrxUXhy6l0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O55164 uniprotkb:P89079 intact:EBI-7401093|intact:MINT-143896|ensembl:ENSRNOP00000051321 intact:EBI-7401124|intact:MINT-431542 psi-mi:mpdz_rat(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:e4or1_ade09(display_long)|uniprotkb:E4(gene name)|psi-mi:E4(display_short)|uniprotkb:Probable dUTPase E4 ORF1(gene name synonym)|uniprotkb:Early E4 14.0 kDa protein(gene name synonym)|uniprotkb:ORF1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lee et al. (2000) pubmed:11000240|mint:MINT-5213021|doi:10.1128/JVI.74.20.9680-9693.2000 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10527(hadv-9)|taxid:10527(Human adenovirus D serotype 9) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7401472|mint:MINT-69632 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062069.1|rgd:3105|ensembl:ENSRNOG00000007894(gene)|ensembl:ENSRNOT00000051028(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O55164|rcsb pdb:1Y76|rcsb pdb:5DTH|mint:MINT-431735(identity) mint:P89079|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR029054|interpro:IPR036157|dip:DIP-44835N|mint:MINT-431725(identity) - comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses|comment:"Stoichiometry: 1.0" comment:mint|comment:homomint|function:Plays a key role in virus oncogenecity in animals. Binds and sequesters human MUPP1/MPDZ protein in the cytoplasm, preventing it from playing a role in cellular proliferation regulation. Induces cell transformation, probably by inactivating MPDZ protein|comment:"Stoichiometry: 1.0" figure legend:F6|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10116(rat-cref)|taxid:10116(Rattus norvegicus) - 2005/11/17 2014/10/16 rogid:vn3E16p8JreR8o+dedW/axYCqEg10116 rogid:NtuDlTWsr1MWfNM4ARULmS3kn/U10527 intact-crc:0FEA328E3B950D8E|rigid:mjNEmIL+76/C+qwwEtrxUXhy6l0 false - ha tag:?-?(MINT-431729)|mutation decreasing interaction:124-124,122-122(MINT-431726) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)