#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10041	uniprotkb:P07207	intact:EBI-115346|uniprotkb:Q6T3F7|uniprotkb:Q6T3G1|uniprotkb:Q6T3G7|uniprotkb:Q6T3G8|uniprotkb:Q6T3H0|uniprotkb:Q6T3H3|uniprotkb:Q6T3I3|uniprotkb:Q6T3I5|uniprotkb:Q6T3I7|uniprotkb:Q6T3J1|uniprotkb:Q6T3J2|uniprotkb:Q6T3J3|uniprotkb:Q6T3J4|uniprotkb:Q6T3K0|uniprotkb:Q6T3K1|uniprotkb:Q6T3K9|uniprotkb:Q6T3L5|uniprotkb:Q6T3L7|uniprotkb:Q6T3L9|uniprotkb:Q6T3M2|uniprotkb:Q6T3M4|uniprotkb:Q6T3M7|uniprotkb:Q6T3N1|uniprotkb:Q6T3N3|uniprotkb:Q6T3N5|uniprotkb:Q6T3N7|uniprotkb:Q6T4M9|uniprotkb:Q6T4N0|uniprotkb:Q6T4N1|uniprotkb:Q6T4N2|uniprotkb:Q6T4N3|uniprotkb:Q6T4N4|uniprotkb:Q6T4N6|uniprotkb:Q95RM9|uniprotkb:Q99108|uniprotkb:Q9VDY2|ensemblmetazoa:FBpp0083153|ensemblmetazoa:FBpp0083154|ensemblmetazoa:FBpp0293200	intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201	psi-mi:dl_drome(display_long)|uniprotkb:Dl(gene name)|psi-mi:Dl(display_short)|uniprotkb:CG3619(orf name)	psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Bruckner et al. (2000)	pubmed:10935637	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-492642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001247193.1|refseq:NP_477264.1|refseq:NP_732412.1|flybase:FBgn0000463|ensemblmetazoa:FBgn0000463(gene)|ensemblmetazoa:FBtr0083739(transcript)|ensemblmetazoa:FBtr0083740(transcript)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|ensemblmetazoa:FBtr0304658(transcript)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045466"(R7 cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|rcsb pdb:4XIB|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0001708"(cell fate specification)|dip:DIP-22726N	refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N	-	-	-	comment:Extracellular domain of Dl is bound to alkaline phosphatase, enzymatic assay is used to measure interaction|stimulant:"Fringe (fng, Q24342) stimulates Dl binding to N"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/02/09	2014/10/16	rogid:2fMti94FA6yxkjlH7kgvKFV8gSM7227	rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227	intact-crc:0D6396A44727BCC5|rigid:PIo2x6TYU0AJ8rdQecSONE5alDo	false	tag:592-592|binding-associated region:1-592(IPR006209)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07207	uniprotkb:P10041	intact:EBI-103438|uniprotkb:O97458|uniprotkb:P04154|uniprotkb:Q9W4T8|ensemblmetazoa:FBpp0070483|ensemblmetazoa:FBpp0293201	intact:EBI-115346|uniprotkb:Q6T3F7|uniprotkb:Q6T3G1|uniprotkb:Q6T3G7|uniprotkb:Q6T3G8|uniprotkb:Q6T3H0|uniprotkb:Q6T3H3|uniprotkb:Q6T3I3|uniprotkb:Q6T3I5|uniprotkb:Q6T3I7|uniprotkb:Q6T3J1|uniprotkb:Q6T3J2|uniprotkb:Q6T3J3|uniprotkb:Q6T3J4|uniprotkb:Q6T3K0|uniprotkb:Q6T3K1|uniprotkb:Q6T3K9|uniprotkb:Q6T3L5|uniprotkb:Q6T3L7|uniprotkb:Q6T3L9|uniprotkb:Q6T3M2|uniprotkb:Q6T3M4|uniprotkb:Q6T3M7|uniprotkb:Q6T3N1|uniprotkb:Q6T3N3|uniprotkb:Q6T3N5|uniprotkb:Q6T3N7|uniprotkb:Q6T4M9|uniprotkb:Q6T4N0|uniprotkb:Q6T4N1|uniprotkb:Q6T4N2|uniprotkb:Q6T4N3|uniprotkb:Q6T4N4|uniprotkb:Q6T4N6|uniprotkb:Q95RM9|uniprotkb:Q99108|uniprotkb:Q9VDY2|ensemblmetazoa:FBpp0083153|ensemblmetazoa:FBpp0083154|ensemblmetazoa:FBpp0293200	psi-mi:notch_drome(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:CG3936(orf name)	psi-mi:dl_drome(display_long)|uniprotkb:Dl(gene name)|psi-mi:Dl(display_short)|uniprotkb:CG3619(orf name)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Bruckner et al. (2000)	pubmed:10935637	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-492662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476859.2|flybase:FBgn0004647|ensemblmetazoa:FBgn0004647(gene)|ensemblmetazoa:FBtr0070507(transcript)|ensemblmetazoa:FBtr0304659(transcript)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002213"(defense response to insect)|go:"GO:0003682"(chromatin binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007297"(ovarian follicle cell migration)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007391"(dorsal closure)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009608"(response to symbiont)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014019"(neuroblast development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007478"(leg disc morphogenesis)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0016348"(imaginal disc-derived leg joint morphogenesis)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0007498"(mesoderm development)|go:"GO:0007521"(muscle cell fate determination)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035167"(larval lymph gland hemopoiesis)|go:"GO:0035171"(lamellocyte differentiation)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0007616"(long-term memory)|go:"GO:0035204"(negative regulation of lamellocyte differentiation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0035214"(eye-antennal disc development)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040008"(regulation of growth)|go:"GO:0042686"(regulation of cardioblast cell fate specification)|go:"GO:0042688"(crystal cell differentiation)|go:"GO:0042691"(positive regulation of crystal cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045316"(negative regulation of compound eye photoreceptor development)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0045466"(R7 cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048052"(R1/R6 cell differentiation)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0048477"(oogenesis)|go:"GO:0048542"(lymph gland development)|go:"GO:0048627"(myoblast development)|go:"GO:0048664"(neuron fate determination)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048749"(compound eye development)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050699"(WW domain binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050877"(nervous system process)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0060289"(compartment boundary maintenance)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:0061382"(Malpighian tubule tip cell differentiation)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:1990433"(CSL-Notch-Mastermind transcription factor complex)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1OT8|rcsb pdb:2JMF|refseq:NP_001245510.1|dip:DIP-5N	refseq:NP_001247193.1|refseq:NP_477264.1|refseq:NP_732412.1|flybase:FBgn0000463|ensemblmetazoa:FBgn0000463(gene)|ensemblmetazoa:FBtr0083739(transcript)|ensemblmetazoa:FBtr0083740(transcript)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|ensemblmetazoa:FBtr0304658(transcript)|go:"GO:0048190"(wing disc dorsal/ventral pattern formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036011"(imaginal disc-derived leg segmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048800"(antennal morphogenesis)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045466"(R7 cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|rcsb pdb:4XIB|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046331"(lateral inhibition)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048056"(R3/R4 cell differentiation)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007475"(apposition of dorsal and ventral imaginal disc-derived wing surfaces)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016330"(second mitotic wave involved in compound eye morphogenesis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0001708"(cell fate specification)|dip:DIP-22726N	-	-	-	comment:N-termins of N is bound to alkaline phosphatase, enzymatic assay is used to measure interaction|stimulant:"Fringe (fng, Q24342) stimulates Dl binding to N"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/02/09	2014/10/16	rogid:T1iHJGMHXkhxbFRybmSDlizN7oQ7227	rogid:2fMti94FA6yxkjlH7kgvKFV8gSM7227	intact-crc:3C33BDAFE73F6C93|rigid:PIo2x6TYU0AJ8rdQecSONE5alDo	false	tag:1467-1467|binding-associated region:1-1467(IPR006209)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)