#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P50527	uniprotkb:P40996	intact:EBI-767318|ensemblfungi:"SPBC1604.14c.1:pep"	intact:EBI-767302|ensemblfungi:"SPAC22H10.07.1:pep"	psi-mi:ste20_schpo(display_long)|uniprotkb:shk1(gene name)|psi-mi:shk1(display_short)|uniprotkb:orb2(gene name synonym)|uniprotkb:pak1(gene name synonym)|uniprotkb:SPBC1604.14c(orf name)|uniprotkb:ste20(gene name synonym)	psi-mi:scd2_schpo(display_long)|uniprotkb:ral3(gene name synonym)|uniprotkb:SPAC22H10.07(orf name)|uniprotkb:scd2(gene name)|psi-mi:scd2(display_short)	psi-mi:"MI:0047"(far western blotting)	Chang et al. (1999)	pubmed:10567532|mint:MINT-5211996	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-767314	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596626.1|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5627123|reactome:R-SPO-5687128|dip:DIP-949N|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120105"(mitotic actomyosin contractile ring, intermediate layer)|go:"GO:1903472"(negative regulation of mitotic actomyosin contractile ring contraction)|go:"GO:2000247"(positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|ensemblfungi:SPBC1604.14c(gene)|ensemblfungi:SPBC1604.14c.1(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032153"(cell division site)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051286"(cell tip)|go:"GO:0061161"(positive regulation of establishment of bipolar cell polarity regulating cell shape)|go:"GO:0062038"(positive regulation of pheromone response MAPK cascade)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071521"(Cdc42 GTPase complex)|reactome:R-SPO-9013148|reactome:R-SPO-9013405|reactome:R-SPO-9013406	refseq:NP_593744.1|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR030507|interpro:IPR036028|interpro:IPR036871|reactome:R-SPO-5668599|ensemblfungi:SPAC22H10.07(gene)|ensemblfungi:SPAC22H10.07.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051286"(cell tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR018247|reactome:R-SPO-1236973|reactome:R-SPO-3299685|reactome:R-SPO-9013148	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/14	2014/10/16	rogid:07tax+Ex/WhxY+isLodwTrZcGlA284812	rogid:8pVLuwhCoDW2nQTMcFKfAOqJ72s284812	intact-crc:8054D1A7E85CF3A9|rigid:2+PRfXTYAS2ddxpgZd6LjbuMbdA	false	his tag:?-?	binding-associated region:1-184|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50527	uniprotkb:P40996	intact:EBI-767318|ensemblfungi:"SPBC1604.14c.1:pep"	intact:EBI-767302|ensemblfungi:"SPAC22H10.07.1:pep"	psi-mi:ste20_schpo(display_long)|uniprotkb:shk1(gene name)|psi-mi:shk1(display_short)|uniprotkb:orb2(gene name synonym)|uniprotkb:pak1(gene name synonym)|uniprotkb:SPBC1604.14c(orf name)|uniprotkb:ste20(gene name synonym)	psi-mi:scd2_schpo(display_long)|uniprotkb:ral3(gene name synonym)|uniprotkb:SPAC22H10.07(orf name)|uniprotkb:scd2(gene name)|psi-mi:scd2(display_short)	psi-mi:"MI:0018"(two hybrid)	Chang et al. (1999)	pubmed:10567532|mint:MINT-5211996	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-767424	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596626.1|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5627123|reactome:R-SPO-5687128|dip:DIP-949N|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120105"(mitotic actomyosin contractile ring, intermediate layer)|go:"GO:1903472"(negative regulation of mitotic actomyosin contractile ring contraction)|go:"GO:2000247"(positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|ensemblfungi:SPBC1604.14c(gene)|ensemblfungi:SPBC1604.14c.1(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032153"(cell division site)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051286"(cell tip)|go:"GO:0061161"(positive regulation of establishment of bipolar cell polarity regulating cell shape)|go:"GO:0062038"(positive regulation of pheromone response MAPK cascade)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071521"(Cdc42 GTPase complex)|reactome:R-SPO-9013148|reactome:R-SPO-9013405|reactome:R-SPO-9013406	refseq:NP_593744.1|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR030507|interpro:IPR036028|interpro:IPR036871|reactome:R-SPO-5668599|ensemblfungi:SPAC22H10.07(gene)|ensemblfungi:SPAC22H10.07.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051286"(cell tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR018247|reactome:R-SPO-1236973|reactome:R-SPO-3299685|reactome:R-SPO-9013148	-	-	-	-	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2005/12/14	2014/10/16	rogid:07tax+Ex/WhxY+isLodwTrZcGlA284812	rogid:8pVLuwhCoDW2nQTMcFKfAOqJ72s284812	intact-crc:41F491490D21370B|rigid:2+PRfXTYAS2ddxpgZd6LjbuMbdA	false	binding-associated region:1-146	binding-associated region:114-177(IPR001452)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01112	uniprotkb:P50527	intact:EBI-767502|ensemblfungi:"SPAC110.03.1:pep"	intact:EBI-767318|ensemblfungi:"SPBC1604.14c.1:pep"	psi-mi:cdc42_schpo(display_long)|uniprotkb:CDC42Sp(gene name synonym)|uniprotkb:cdc42(gene name)|psi-mi:cdc42(display_short)|uniprotkb:SPAC110.03(orf name)	psi-mi:ste20_schpo(display_long)|uniprotkb:shk1(gene name)|psi-mi:shk1(display_short)|uniprotkb:orb2(gene name synonym)|uniprotkb:pak1(gene name synonym)|uniprotkb:SPBC1604.14c(orf name)|uniprotkb:ste20(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chang et al. (1999)	pubmed:10567532|mint:MINT-5211996	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-767479	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593536.1|dip:DIP-275N|mint:Q01112|ensemblfungi:SPAC110.03(gene)|ensemblfungi:SPAC110.03.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032951"(regulation of beta-glucan biosynthetic process)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5626467|reactome:R-SPO-5627123|reactome:R-SPO-5687128|reactome:R-SPO-9013148|reactome:R-SPO-9013406|reactome:R-SPO-9013409|go:"GO:0006897"(endocytosis)	refseq:NP_596626.1|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5627123|reactome:R-SPO-5687128|dip:DIP-949N|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120105"(mitotic actomyosin contractile ring, intermediate layer)|go:"GO:1903472"(negative regulation of mitotic actomyosin contractile ring contraction)|go:"GO:2000247"(positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|ensemblfungi:SPBC1604.14c(gene)|ensemblfungi:SPBC1604.14c.1(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032153"(cell division site)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051286"(cell tip)|go:"GO:0061161"(positive regulation of establishment of bipolar cell polarity regulating cell shape)|go:"GO:0062038"(positive regulation of pheromone response MAPK cascade)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071521"(Cdc42 GTPase complex)|reactome:R-SPO-9013148|reactome:R-SPO-9013405|reactome:R-SPO-9013406	-	-	-	stimulant:"Scd2 (P40996) stimulated binding of Shk1 and Cdc42."	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2005/12/14	2014/10/16	rogid:Hm+T2A2V+AZYh2VtuqATJiUDgUI284812	rogid:07tax+Ex/WhxY+isLodwTrZcGlA284812	intact-crc:CCF8A6DC5C37B2E2|rigid:LgS9+qoEMmtU4bdzQt9wIp+Q2XQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40996	uniprotkb:P50527	intact:EBI-767302|ensemblfungi:"SPAC22H10.07.1:pep"	intact:EBI-767318|ensemblfungi:"SPBC1604.14c.1:pep"	psi-mi:scd2_schpo(display_long)|uniprotkb:ral3(gene name synonym)|uniprotkb:SPAC22H10.07(orf name)|uniprotkb:scd2(gene name)|psi-mi:scd2(display_short)	psi-mi:ste20_schpo(display_long)|uniprotkb:shk1(gene name)|psi-mi:shk1(display_short)|uniprotkb:orb2(gene name synonym)|uniprotkb:pak1(gene name synonym)|uniprotkb:SPBC1604.14c(orf name)|uniprotkb:ste20(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Chang et al. (1999)	pubmed:10567532|mint:MINT-5211996	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-767474	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593744.1|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR035548|interpro:IPR035549|interpro:IPR035550|interpro:IPR030507|interpro:IPR036028|interpro:IPR036871|reactome:R-SPO-5668599|ensemblfungi:SPAC22H10.07(gene)|ensemblfungi:SPAC22H10.07.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051286"(cell tip)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR018247|reactome:R-SPO-1236973|reactome:R-SPO-3299685|reactome:R-SPO-9013148	refseq:NP_596626.1|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5627123|reactome:R-SPO-5687128|dip:DIP-949N|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120105"(mitotic actomyosin contractile ring, intermediate layer)|go:"GO:1903472"(negative regulation of mitotic actomyosin contractile ring contraction)|go:"GO:2000247"(positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|ensemblfungi:SPBC1604.14c(gene)|ensemblfungi:SPBC1604.14c.1(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032153"(cell division site)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051286"(cell tip)|go:"GO:0061161"(positive regulation of establishment of bipolar cell polarity regulating cell shape)|go:"GO:0062038"(positive regulation of pheromone response MAPK cascade)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071521"(Cdc42 GTPase complex)|reactome:R-SPO-9013148|reactome:R-SPO-9013405|reactome:R-SPO-9013406	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/14	2014/10/16	rogid:8pVLuwhCoDW2nQTMcFKfAOqJ72s284812	rogid:07tax+Ex/WhxY+isLodwTrZcGlA284812	intact-crc:C10E75A4A86EA170|rigid:2+PRfXTYAS2ddxpgZd6LjbuMbdA	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)