#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P46937	uniprotkb:O14745	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143244|mint:MINT-72745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N|mint:MINT-377112(identity)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377117(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6A|comment:homomint|comment:mint	taxid:9606(human-16hbe 14o)|taxid:9606(Homo sapiens)	-	2005/11/28	2014/10/16	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	intact-crc:E241E9E548989ADB|rigid:fMiIcPUUiDvqIDJx/hr/grgVAYo	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O14745	uniprotkb:P46937	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143327|mint:MINT-72747	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377014(identity)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N|mint:MINT-377005(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6B|comment:homomint|comment:mint	taxid:9606(human-16hbe 14o)|taxid:9606(Homo sapiens)	-	2005/11/28	2014/10/16	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	intact-crc:4A2C92CC8668DC14|rigid:fMiIcPUUiDvqIDJx/hr/grgVAYo	false	-	tag:?-?(MINT-377008)|mutation decreasing interaction:450-454(MINT-377006)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O14745	uniprotkb:P46937	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143494|mint:MINT-72736	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377152(identity)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N|mint:MINT-377143(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2C|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/28	2014/10/16	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	intact-crc:EBFE3013D8F58B67|rigid:fMiIcPUUiDvqIDJx/hr/grgVAYo	false	-	mutation decreasing interaction:444-454(MINT-377144)|tag:?-?(MINT-377146)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46937	uniprotkb:O14745	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143535|mint:MINT-72740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N|mint:MINT-377024(identity)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377033(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2D|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/28	2014/10/16	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	intact-crc:E8DB4D9B74F48E0A|rigid:fMiIcPUUiDvqIDJx/hr/grgVAYo	false	tag:?-?(MINT-377027)|mutation decreasing interaction:444-454(MINT-377025)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14745	uniprotkb:P46937	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143614|mint:MINT-72738	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377048(identity)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N|mint:MINT-377043(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/28	2014/10/16	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	intact-crc:0853BD075C1BFCE8|rigid:fMiIcPUUiDvqIDJx/hr/grgVAYo	false	glutathione s tranferase tag:?-?(MINT-377049)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P07947	uniprotkb:O14745	intact:EBI-515331|uniprotkb:A6NLB3|uniprotkb:D3DUH1|intact:EBI-28995389|ensembl:ENSP00000324740|ensembl:ENSP00000462468	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	psi-mi:yes_human(display_long)|uniprotkb:p61-Yes(gene name synonym)|uniprotkb:Proto-oncogene c-Yes(gene name synonym)|uniprotkb:YES1(gene name)|psi-mi:YES1(display_short)|uniprotkb:YES(gene name synonym)	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143754|mint:MINT-72749	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016881449.1|refseq:NP_005424.1|ensembl:ENSP00000324740|ensembl:ENSP00000462468|dip:DIP-33849N|ensembl:ENSG00000176105(gene)|ensembl:ENST00000314574(transcript)|ensembl:ENST00000584307(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050900"(leukocyte migration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035751|interpro:IPR036028|interpro:IPR036860|mint:P07947|rcsb pdb:2HDA|reactome:R-HSA-1227986|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2682334|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-8940973|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439|mint:MINT-377135(identity)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377125(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F8B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/28	2014/10/16	rogid:Wo+NWxPVSmF8W6ZHQmTPpg3YuY09606	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	intact-crc:2C8C76E79827E840|rigid:aX3V3j+eGLgSUXNJoGq4O7q9Zro	false	-	binding-associated region:150-237(MINT-377126)|glutathione s tranferase tag:?-?(MINT-377129)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46937	uniprotkb:O14745	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143687|mint:MINT-72744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N|mint:MINT-377074(identity)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377081(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5C|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/28	2014/10/16	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	intact-crc:3D301134BF26F01A|rigid:fMiIcPUUiDvqIDJx/hr/grgVAYo	false	tag:?-?(MINT-377075)	glutathione s tranferase tag:?-?(MINT-377085)|binding-associated region:150-237(MINT-377082)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46937	uniprotkb:O14745	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143874|mint:MINT-72743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N|mint:MINT-377060(identity)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377065(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:EBP50 and Yap65 are co-distributed in the apical membrane of the human nasal epithelia.|comment:homomint|comment:mint	taxid:10090(mouse-nasal epitheli)|taxid:10090(Mus musculus)	-	2005/11/28	2014/10/16	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	intact-crc:802929467440CBF0|rigid:fMiIcPUUiDvqIDJx/hr/grgVAYo	false	-	-	-	-	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:P46937	uniprotkb:O14745	intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	Mohler et al. (1999)	pubmed:10562288|mint:MINT-5211984	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7143915|mint:MINT-72741	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N|mint:MINT-377096(identity)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N|mint:MINT-377104(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3C|comment:homomint|comment:mint	taxid:10090(mouse-16hbe 14o)|taxid:10090(Mus musculus)	-	2005/11/28	2014/10/16	rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	intact-crc:53B1DFDCB257B402|rigid:fMiIcPUUiDvqIDJx/hr/grgVAYo	false	mutation decreasing interaction:171-209,444-454(MINT-377097)	-	-	-	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)