#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P50542	uniprotkb:O00623	intact:EBI-597835|uniprotkb:Q15115|uniprotkb:Q15266|uniprotkb:Q96FN7|uniprotkb:B7ZAD5|uniprotkb:A8K891|uniprotkb:D3DUT8|uniprotkb:B4DZ45|intact:EBI-28971432|ensembl:ENSP00000400647|ensembl:ENSP00000410159|ensembl:ENSP00000499823|ensembl:ENSP00000500509|ensembl:ENSP00000502374	intact:EBI-594836|uniprotkb:B2R6M2|ensembl:ENSP00000225873	psi-mi:pex5_human(display_long)|uniprotkb:Peroxisome receptor 1(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:PEX5(gene name)|psi-mi:PEX5(display_short)|uniprotkb:PXR1(gene name synonym)	psi-mi:pex12_human(display_long)|uniprotkb:Peroxisome assembly factor 3(gene name synonym)|uniprotkb:PEX12(gene name)|psi-mi:PEX12(display_short)|uniprotkb:PAF3(gene name synonym)|uniprotkb:Peroxin-12(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chang et al. (1999)	pubmed:10562279	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-597831	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000266563|ensembl:ENSP00000266563|ensembl:ENST00000266564|ensembl:ENSP00000266564|ensembl:ENSP00000410159|ensembl:ENST00000434354|ensembl:ENSP00000407401|ensembl:ENSP00000400647|ensembl:ENSP00000500509|ensembl:ENST00000672242|ensembl:ENSP00000500696|ensembl:ENST00000672541|ensembl:ENSP00000500043|ensembl:ENSP00000499823|ensembl:ENST00000672776|ensembl:ENSP00000500230|ensembl:ENSP00000502374|refseq:NP_001287718.1|refseq:XP_011519097.1|refseq:XP_011519099.1|refseq:XP_011519100.1|refseq:XP_011519101.1|refseq:XP_011519102.1|refseq:NP_000310.2|refseq:NP_001124496.1|refseq:NP_001124497.1|refseq:NP_001124498.1|refseq:XP_016875237.1|refseq:XP_016875238.1|refseq:NP_001124495.1|dip:DIP-34654N|refseq:XP_016875239.1|refseq:XP_016875241.1|refseq:XP_016875242.1|refseq:XP_016875243.1|refseq:XP_016875244.1|ensembl:ENSG00000139197(gene)|ensembl:ENSG00000288217(gene)|ensembl:ENST00000420616(transcript)|ensembl:ENST00000455147(transcript)|ensembl:ENST00000671993(transcript)|ensembl:ENST00000672694(transcript)|ensembl:ENST00000675855(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|interpro:IPR024113|mint:P50542|rcsb pdb:1FCH|rcsb pdb:2C0L|rcsb pdb:2C0M|rcsb pdb:2J9Q|rcsb pdb:2W84|rcsb pdb:3R9A|rcsb pdb:4BXU|rcsb pdb:4KXK|rcsb pdb:4KYO|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9664873	refseq:NP_000277.1|ensembl:ENSG00000108733(gene)|ensembl:ENST00000225873(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006845(Pex, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017375(Peroxisome assembly, p12)|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9603798	-	-	-	disease:Mutations in PEX12 result in Zellweger syndrome.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/06/13	2014/10/16	rogid:eTada01hgbdLE6GcBY29EGX+7QI9606	rogid:QrKkfoUDAZE2QfWwRY1IhGIBSiE9606	intact-crc:88C0D515817D30E3|rigid:NNYNdazj67OupmuiFBnphSYe59s	false	-	binding-associated region:259-359	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50542	uniprotkb:O00623	intact:EBI-597835|uniprotkb:Q15115|uniprotkb:Q15266|uniprotkb:Q96FN7|uniprotkb:B7ZAD5|uniprotkb:A8K891|uniprotkb:D3DUT8|uniprotkb:B4DZ45|intact:EBI-28971432|ensembl:ENSP00000400647|ensembl:ENSP00000410159|ensembl:ENSP00000499823|ensembl:ENSP00000500509|ensembl:ENSP00000502374	intact:EBI-594836|uniprotkb:B2R6M2|ensembl:ENSP00000225873	psi-mi:pex5_human(display_long)|uniprotkb:Peroxisome receptor 1(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:PEX5(gene name)|psi-mi:PEX5(display_short)|uniprotkb:PXR1(gene name synonym)	psi-mi:pex12_human(display_long)|uniprotkb:Peroxisome assembly factor 3(gene name synonym)|uniprotkb:PEX12(gene name)|psi-mi:PEX12(display_short)|uniprotkb:PAF3(gene name synonym)|uniprotkb:Peroxin-12(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Chang et al. (1999)	pubmed:10562279	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-601006	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000266563|ensembl:ENSP00000266563|ensembl:ENST00000266564|ensembl:ENSP00000266564|ensembl:ENSP00000410159|ensembl:ENST00000434354|ensembl:ENSP00000407401|ensembl:ENSP00000400647|ensembl:ENSP00000500509|ensembl:ENST00000672242|ensembl:ENSP00000500696|ensembl:ENST00000672541|ensembl:ENSP00000500043|ensembl:ENSP00000499823|ensembl:ENST00000672776|ensembl:ENSP00000500230|ensembl:ENSP00000502374|refseq:NP_001287718.1|refseq:XP_011519097.1|refseq:XP_011519099.1|refseq:XP_011519100.1|refseq:XP_011519101.1|refseq:XP_011519102.1|refseq:NP_000310.2|refseq:NP_001124496.1|refseq:NP_001124497.1|refseq:NP_001124498.1|refseq:XP_016875237.1|refseq:XP_016875238.1|refseq:NP_001124495.1|dip:DIP-34654N|refseq:XP_016875239.1|refseq:XP_016875241.1|refseq:XP_016875242.1|refseq:XP_016875243.1|refseq:XP_016875244.1|ensembl:ENSG00000139197(gene)|ensembl:ENSG00000288217(gene)|ensembl:ENST00000420616(transcript)|ensembl:ENST00000455147(transcript)|ensembl:ENST00000671993(transcript)|ensembl:ENST00000672694(transcript)|ensembl:ENST00000675855(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|interpro:IPR024113|mint:P50542|rcsb pdb:1FCH|rcsb pdb:2C0L|rcsb pdb:2C0M|rcsb pdb:2J9Q|rcsb pdb:2W84|rcsb pdb:3R9A|rcsb pdb:4BXU|rcsb pdb:4KXK|rcsb pdb:4KYO|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9664873	refseq:NP_000277.1|ensembl:ENSG00000108733(gene)|ensembl:ENST00000225873(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006845(Pex, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017375(Peroxisome assembly, p12)|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9603798	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/06/13	2014/10/16	rogid:eTada01hgbdLE6GcBY29EGX+7QI9606	rogid:QrKkfoUDAZE2QfWwRY1IhGIBSiE9606	intact-crc:835E443E412BB1A7|rigid:NNYNdazj67OupmuiFBnphSYe59s	false	tag:?-?	tag:?-?|binding-associated region:259-359	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00623	uniprotkb:P50542	intact:EBI-594836|uniprotkb:B2R6M2|ensembl:ENSP00000225873	intact:EBI-597835|uniprotkb:Q15115|uniprotkb:Q15266|uniprotkb:Q96FN7|uniprotkb:B7ZAD5|uniprotkb:A8K891|uniprotkb:D3DUT8|uniprotkb:B4DZ45|intact:EBI-28971432|ensembl:ENSP00000400647|ensembl:ENSP00000410159|ensembl:ENSP00000499823|ensembl:ENSP00000500509|ensembl:ENSP00000502374	psi-mi:pex12_human(display_long)|uniprotkb:Peroxisome assembly factor 3(gene name synonym)|uniprotkb:PEX12(gene name)|psi-mi:PEX12(display_short)|uniprotkb:PAF3(gene name synonym)|uniprotkb:Peroxin-12(gene name synonym)	psi-mi:pex5_human(display_long)|uniprotkb:Peroxisome receptor 1(gene name synonym)|uniprotkb:Peroxisomal C-terminal targeting signal import receptor(gene name synonym)|uniprotkb:PTS1-BP(gene name synonym)|uniprotkb:Peroxin-5(gene name synonym)|uniprotkb:PEX5(gene name)|psi-mi:PEX5(display_short)|uniprotkb:PXR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (1999)	pubmed:10562279	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-601763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000277.1|ensembl:ENSG00000108733(gene)|ensembl:ENST00000225873(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006845(Pex, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017375(Peroxisome assembly, p12)|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9603798	ensembl:ENST00000266563|ensembl:ENSP00000266563|ensembl:ENST00000266564|ensembl:ENSP00000266564|ensembl:ENSP00000410159|ensembl:ENST00000434354|ensembl:ENSP00000407401|ensembl:ENSP00000400647|ensembl:ENSP00000500509|ensembl:ENST00000672242|ensembl:ENSP00000500696|ensembl:ENST00000672541|ensembl:ENSP00000500043|ensembl:ENSP00000499823|ensembl:ENST00000672776|ensembl:ENSP00000500230|ensembl:ENSP00000502374|refseq:NP_001287718.1|refseq:XP_011519097.1|refseq:XP_011519099.1|refseq:XP_011519100.1|refseq:XP_011519101.1|refseq:XP_011519102.1|refseq:NP_000310.2|refseq:NP_001124496.1|refseq:NP_001124497.1|refseq:NP_001124498.1|refseq:XP_016875237.1|refseq:XP_016875238.1|refseq:NP_001124495.1|dip:DIP-34654N|refseq:XP_016875239.1|refseq:XP_016875241.1|refseq:XP_016875242.1|refseq:XP_016875243.1|refseq:XP_016875244.1|ensembl:ENSG00000139197(gene)|ensembl:ENSG00000288217(gene)|ensembl:ENST00000420616(transcript)|ensembl:ENST00000455147(transcript)|ensembl:ENST00000671993(transcript)|ensembl:ENST00000672694(transcript)|ensembl:ENST00000675855(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|interpro:IPR024113|mint:P50542|rcsb pdb:1FCH|rcsb pdb:2C0L|rcsb pdb:2C0M|rcsb pdb:2J9Q|rcsb pdb:2W84|rcsb pdb:3R9A|rcsb pdb:4BXU|rcsb pdb:4KXK|rcsb pdb:4KYO|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9664873	-	-	-	figure legend:2c	taxid:9606(human-cls)|taxid:9606("Homo sapiens fibroblast cell line (GM03318)")	-	2005/06/13	2014/10/16	rogid:QrKkfoUDAZE2QfWwRY1IhGIBSiE9606	rogid:eTada01hgbdLE6GcBY29EGX+7QI9606	intact-crc:BCF35E7F89775A76|rigid:NNYNdazj67OupmuiFBnphSYe59s	false	myc tag:?-?	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)