#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P29597	uniprotkb:P04019	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	intact:EBI-1177232	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:ve6_hpv11(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:"MI:0096"(pull down)	Li et al. (1999)	pubmed:10523853|mint:MINT-5211902	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10580(hpv11)|taxid:10580(Human papillomavirus type 11)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7105059|mint:MINT-73132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|mint:MINT-375785(identity)	interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575|mint:P04019|mint:MINT-375778(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/05	2014/10/16	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	rogid:0sQZhDVhgh6i3Uhu40TqER+ONrM10580	intact-crc:D71943D8B9B8B52A|rigid:X59hZw/jYnAsxRkmSUc+Ec5f2sA	false	-	glutathione s tranferase tag:?-?(MINT-375779)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29597	uniprotkb:P06463	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	intact:EBI-1186926	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:"MI:0096"(pull down)	Li et al. (1999)	pubmed:10523853|mint:MINT-5211902	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7104993|mint:MINT-73131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|mint:MINT-375715(identity)	refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N|mint:MINT-375708(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/05	2014/10/16	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761	intact-crc:709F854A9AB4A853|rigid:1AYHXXeMZwS7lP0yganeYBticlM	false	-	glutathione s tranferase tag:?-?(MINT-375709)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06463	uniprotkb:P29597	intact:EBI-1186926	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:"MI:0096"(pull down)	Li et al. (1999)	pubmed:10523853|mint:MINT-5211902	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7105074|mint:MINT-73133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N|mint:MINT-375655(identity)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|mint:MINT-375662(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F8A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/05	2014/10/16	rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	intact-crc:0901C602AD0F37AC|rigid:1AYHXXeMZwS7lP0yganeYBticlM	false	glutathione s tranferase tag:?-?(MINT-375656)	mutation decreasing interaction:1-496(MINT-375663)|tag:?-?(MINT-375665)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29597	uniprotkb:P06463	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	intact:EBI-1186926	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:"MI:0096"(pull down)	Li et al. (1999)	pubmed:10523853|mint:MINT-5211902	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7105156|mint:MINT-74962	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|mint:MINT-375730(identity)	refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N|mint:MINT-375723(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/05	2014/10/16	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761	intact-crc:F27EA211042D6153|rigid:1AYHXXeMZwS7lP0yganeYBticlM	false	-	glutathione s tranferase tag:?-?(MINT-375724)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04019	uniprotkb:P29597	intact:EBI-1177232	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	psi-mi:ve6_hpv11(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:"MI:0096"(pull down)	Li et al. (1999)	pubmed:10523853|mint:MINT-5211902	taxid:10580(hpv11)|taxid:10580(Human papillomavirus type 11)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7105185|mint:MINT-74963	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575|mint:P04019|mint:MINT-375674(identity)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|mint:MINT-375681(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/05	2014/10/16	rogid:0sQZhDVhgh6i3Uhu40TqER+ONrM10580	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	intact-crc:437E1FDA4E2F1BD6|rigid:X59hZw/jYnAsxRkmSUc+Ec5f2sA	false	glutathione s tranferase tag:?-?(MINT-375675)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17181	uniprotkb:P29597	intact:EBI-1547250|uniprotkb:Q53GW9|uniprotkb:Q53H11|uniprotkb:Q8WTZ2|uniprotkb:Q6PKD7|uniprotkb:Q7M4L2|uniprotkb:B4DNT3|uniprotkb:D3DSF0|uniprotkb:B2R6L9|ensembl:ENSP00000270139	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	psi-mi:inar1_human(display_long)|uniprotkb:IFNAR1(gene name)|psi-mi:IFNAR1(display_short)|uniprotkb:IFNAR(gene name synonym)|uniprotkb:Type I interferon receptor 1(gene name synonym)|uniprotkb:Cytokine receptor family 2 member 1(gene name synonym)|uniprotkb:Cytokine receptor class-II member 1(gene name synonym)	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:"MI:0096"(pull down)	Li et al. (1999)	pubmed:10523853|mint:MINT-5211902	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7105130|mint:MINT-73134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000620.2|refseq:XP_005261021.1|dip:DIP-57N|ensembl:ENSG00000142166(gene)|ensembl:ENST00000270139(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004905"(type I interferon receptor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019962"(type I interferon binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR016669(Interferon-alpha/beta receptor 1)|interpro:IPR036116|rcsb pdb:3S98|rcsb pdb:3SE3|rcsb pdb:3SE4|rcsb pdb:4PO6|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191|mint:MINT-375738(identity)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|mint:MINT-375747(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F8B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/05	2014/10/16	rogid:DuOuIr85nya6Ti494f43fftNRyo9606	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	intact-crc:38EC6EEFE13D84DF|rigid:5F2QIZIi/tD/yOUkILohJGmUy+g	false	glutathione s tranferase tag:?-?(MINT-375741)|binding-associated region:465-557(MINT-375739)	mutation decreasing interaction:1-287(MINT-375748)|tag:?-?(MINT-375750)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29597	uniprotkb:P06463	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	intact:EBI-1186926	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:ve6_hpv18(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (1999)	pubmed:10523853|mint:MINT-5211902	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7105287|mint:MINT-73135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|mint:MINT-375698(identity)	refseq:NP_040310.1|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001334(E6 early regulatory protein)|interpro:IPR038575|rcsb pdb:2I04|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:4JOR|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6SJV|rcsb pdb:6ZFD|rcsb pdb:6ZFG|mint:P06463|dip:DIP-44730N|mint:MINT-375691(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F7|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/12/05	2014/10/16	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	rogid:X7TgcVayyyOKnVPXRlcbN6FVtYQ333761	intact-crc:5F0A25938CB494A3|rigid:1AYHXXeMZwS7lP0yganeYBticlM	false	tag:?-?(MINT-375699)	flag tag:?-?(MINT-375692)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29597	uniprotkb:P04019	intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885	intact:EBI-1177232	psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short)	psi-mi:ve6_hpv11(display_long)|uniprotkb:E6(gene name)|psi-mi:E6(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Li et al. (1999)	pubmed:10523853|mint:MINT-5211902	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10580(hpv11)|taxid:10580(Human papillomavirus type 11)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7105328|mint:MINT-73136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|mint:MINT-375768(identity)	interpro:IPR001334(E6 early regulatory protein)|go:"GO:0003677"(DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR038575|mint:P04019|mint:MINT-375761(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F7|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/12/05	2014/10/16	rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606	rogid:0sQZhDVhgh6i3Uhu40TqER+ONrM10580	intact-crc:48C627B17E382E9C|rigid:X59hZw/jYnAsxRkmSUc+Ec5f2sA	false	tag:?-?(MINT-375769)	flag tag:?-?(MINT-375762)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)