#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O54824 uniprotkb:P35436 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082297|mint:MINT-72582 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373092(identity) refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|mint:MINT-373102(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090 intact-crc:BED560C80B542EE1|rigid:xr/MMz/i0KPsMFbVsM9kIyKsdGE false tag:?-?(MINT-373096)|binding-associated region:1-525(MINT-373093) tag:?-?(MINT-373106)|binding-associated region:100-1464(MINT-373103) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:Q00960 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-396905|uniprotkb:Q62684 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:nmde2_rat(display_long)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082339|mint:MINT-72584 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373242(identity) rgd:2738|refseq:NP_036706.1|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010350"(cellular response to magnesium starvation)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904644"(cellular response to curcumin)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3JPW|rcsb pdb:3JPY|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4PE5|rcsb pdb:5B3J|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5TPZ|rcsb pdb:6CNA|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|mint:Q00960|dip:DIP-33702N|mint:MINT-373252(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:dbOLObdhW/ts7GuZ0k8UIII99m010116 intact-crc:CF7574A3A8637E07|rigid:I8pC3Lte1NghSb6uobclduzZSa8 false binding-associated region:1-525(MINT-373243)|tag:?-?(MINT-373246) binding-associated region:1289-1482(MINT-373253)|tag:?-?(MINT-373256) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:Q00961 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-631045 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:nmde3_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2C(gene name synonym)|uniprotkb:Grin2c(gene name)|psi-mi:Grin2c(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082365|mint:MINT-72585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373115(identity) rgd:2739|refseq:NP_036707.3|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR018884|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009611"(response to wounding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0033058"(directional locomotion)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|refseq:XP_006247769.1|refseq:XP_006247771.1|interpro:IPR028082|refseq:XP_017452475.1|refseq:XP_017452476.1|refseq:XP_017452477.1|refseq:XP_017452478.1|refseq:XP_017452479.1|refseq:XP_017452480.1|refseq:XP_017452481.1|reactome:R-RNO-438066|reactome:R-RNO-8849932|reactome:R-RNO-9609736|mint:MINT-373125(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:DNWgJGwL2992SEfrd3xZwHfJmdY10116 intact-crc:C750AB48798E88E5|rigid:Bitkf/dWqFvUEmr0t0iOTZe73Ik false tag:?-?(MINT-373119)|binding-associated region:1-525(MINT-373116) tag:?-?(MINT-373129)|binding-associated region:975-1237(MINT-373126) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62645 uniprotkb:O54824 intact:EBI-631067|uniprotkb:Q63381|uniprotkb:Q63382|uniprotkb:Q63729|uniprotkb:Q63730|ensembl:ENSRNOP00000028615 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 psi-mi:nmde4_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2D(gene name synonym)|uniprotkb:Grin2d(gene name)|psi-mi:Grin2d(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-4(gene name synonym)|uniprotkb:GluN2D(gene name synonym) psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082427|mint:MINT-72587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2740|refseq:NP_073634.1|ensembl:ENSRNOG00000021063(gene)|ensembl:ENSRNOT00000028615(transcript)|go:"GO:0001964"(startle response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016595"(glutamate binding)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3OEK|rcsb pdb:3OEL|rcsb pdb:3OEM|rcsb pdb:3OEN|rcsb pdb:4JWY|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|refseq:XP_008757539.1|mint:MINT-373229(identity) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373219(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:EI0xEBqUTBpq1D93yQqU4XLHdc810116 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 intact-crc:45B82BA1418C45B4|rigid:jGfpkqc7z7GNoEZaaSFpklm03yE false tag:?-?(MINT-373233)|binding-associated region:1096-1323(MINT-373230) tag:?-?(MINT-373223)|binding-associated region:1-525(MINT-373220) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:P35561 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-703793|ensembl:ENSMUSP00000037192 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:kcnj2_mouse(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.1"(gene name synonym)|uniprotkb:Kcnj2(gene name)|psi-mi:Kcnj2(display_short)|uniprotkb:Irk1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082468|mint:MINT-72589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373401(identity) refseq:NP_032451.1|ensembl:ENSMUSG00000041695(gene)|ensembl:ENSMUST00000042970(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014704"(intercalated disc)|go:"GO:0014861"(regulation of skeletal muscle contraction via regulation of action potential)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003271(Potassium channel, inwardly rectifying, Kir2.1)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR013673(Potassium channel, inwardly rectifying, Kir, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:P35561|rcsb pdb:1U4F|rcsb pdb:2GIX|rcsb pdb:2XKY|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272|mint:MINT-373411(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:g9tvgEkng4AEzSRbx9ujR4nPPrQ10090 intact-crc:55970D52BBD9D996|rigid:+ZgRhVF/P+8KCO1gtzx27SwmIZs false tag:?-?(MINT-373405)|binding-associated region:1-525(MINT-373402) binding-associated region:252-428(MINT-373412)|tag:?-?(MINT-373415) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P52189 uniprotkb:O54824 intact:EBI-2309692 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 psi-mi:kcnj4_mouse(display_long)|uniprotkb:Kcnj4(gene name)|psi-mi:Kcnj4(display_short)|uniprotkb:Irk3(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 4(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir2.3"(gene name synonym) psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082523|mint:MINT-72590 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003273(Potassium channel, inwardly rectifying, Kir2.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR040445|interpro:IPR041647|reactome:R-MMU-1296041|reactome:R-MMU-1296053|reactome:R-MMU-5576886|reactome:R-MMU-997272|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|mint:MINT-373322(identity) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373312(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:o71idIrcU8IP7uaiSD/QJ/1NiBk10090 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 intact-crc:B961C01256F1AD49|rigid:E1W0MvCQEZbuaNeyAe1/LS9ZgRI false tag:?-?(MINT-373326)|binding-associated region:280-445(MINT-373323) tag:?-?(MINT-373316)|binding-associated region:1-525(MINT-373313) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:P49655 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-706185|uniprotkb:Q62790 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:kcj10_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 10(gene name synonym)|uniprotkb:ATP-sensitive inward rectifier potassium channel KAB-2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.1"(gene name synonym)|uniprotkb:BIR10(gene name synonym)|uniprotkb:"Brain-specific inwardly rectifying K(+) channel 1"(gene name synonym)|uniprotkb:Kcnj10(gene name)|psi-mi:Kcnj10(display_short)|uniprotkb:Kab-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082576|mint:MINT-72591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373138(identity) refseq:NP_113790.2|refseq:XP_008767959.1|rgd:61822|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003269(Potassium channel, inwardly rectifying, Kir1.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|refseq:XP_017454263.1|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296067|reactome:R-RNO-997272|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007601"(visual perception)|go:"GO:0007628"(adult walking behavior)|go:"GO:0009637"(response to blue light)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051935"(glutamate reuptake)|go:"GO:0051938"(L-glutamate import)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|mint:MINT-373148(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:ri6d3VbUvSLj12uMiqruQGL09sE10116 intact-crc:26BDB3BB2543CA05|rigid:nMvbHmfzJy8pjiE3IjdjC44YoOc false tag:?-?(MINT-373142)|binding-associated region:1-525(MINT-373139) tag:?-?(MINT-373149) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99712 uniprotkb:O54824 intact:EBI-7082607|ensembl:ENSP00000331698|ensembl:ENSP00000381904|ensembl:ENSP00000381905|ensembl:ENSP00000381907|ensembl:ENSP00000381911|ensembl:ENSP00000479100|ensembl:ENSP00000484960|intact:MINT-103775|uniprotkb:Q96L28|uniprotkb:D3DSH5|uniprotkb:Q99446|uniprotkb:O00564 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 psi-mi:kcj15_human(display_long)|uniprotkb:KCNJ15(gene name)|psi-mi:KCNJ15(display_short)|uniprotkb:KCNJ14(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 15(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.2"(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir1.3"(gene name synonym) psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082602|mint:MINT-72594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011527862.1|refseq:XP_011527863.1|ensembl:ENSG00000157551(gene)|ensembl:ENST00000328656(transcript)|ensembl:ENST00000398930(transcript)|ensembl:ENST00000398932(transcript)|ensembl:ENST00000398934(transcript)|ensembl:ENST00000398938(transcript)|ensembl:ENST00000612702(transcript)|ensembl:ENST00000613499(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003270(Potassium channel, inwardly rectifying, Kir1.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-HSA-1296041|reactome:R-HSA-997272|refseq:XP_016883832.1|refseq:XP_016883833.1|refseq:XP_016883834.1|refseq:NP_001263365.1|refseq:NP_733933.1|refseq:NP_001263368.1|refseq:NP_001263366.1|refseq:NP_002234.2|refseq:NP_001263364.1|refseq:NP_001263367.1|refseq:NP_733932.1|refseq:XP_005261032.1|refseq:XP_006724065.1|mint:MINT-373389(identity) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373379(identity) - comment:mint|function:Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:TiE/A9/tLsonRMg7/KsThkWgr8Q9606 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 intact-crc:91486BD94758202F|rigid:vHM+Xeu2KtFU4qo9A8/8xBoxbUA false binding-associated region:245-375(MINT-373390)|tag:?-?(MINT-373392) binding-associated region:1-525(MINT-373380)|tag:?-?(MINT-373383) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03719 uniprotkb:O54824 intact:EBI-7082666|ensembl:ENSMUSP00000009875|intact:MINT-103872|uniprotkb:Q8CC68 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 psi-mi:kcnd1_mouse(display_long)|uniprotkb:Kcnd1(gene name)|psi-mi:Kcnd1(display_short)|uniprotkb:Voltage-gated potassium channel subunit Kv4.1(gene name synonym) psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082661|mint:MINT-72595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009731(gene)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005250"("A-type (transient outward) potassium channel activity")|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003975(Potassium channel, voltage dependent, Kv4)|interpro:IPR004054(Potassium channel, voltage dependent, Kv4.1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR021645|interpro:IPR024587|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576894|ensembl:ENSMUST00000009875(transcript)|refseq:NP_032449.1|mint:MINT-373183(identity) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373173(identity) - comment:mint|function:"Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in the heart and I(Sa) current in neurons. Channel properties are modulated by subunit assembly"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:FY0ywmK7ArI3GaOFhGFtidurjHY10090 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 intact-crc:229E483CD247D435|rigid:gPB6RANDrCEowE3SBpOT//T/yEg false binding-associated region:409-651(MINT-373184)|tag:?-?(MINT-373187) binding-associated region:1-525(MINT-373174)|tag:?-?(MINT-373177) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63881 uniprotkb:O54824 intact:EBI-959735|uniprotkb:Q00090|uniprotkb:Q99249 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 psi-mi:kcnd2_rat(display_long)|uniprotkb:Kcnd2(gene name)|psi-mi:Kcnd2(display_short)|uniprotkb:Voltage-gated potassium channel subunit Kv4.2(gene name synonym)|uniprotkb:Shal1(gene name synonym)|uniprotkb:RK5(gene name synonym) psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082828|mint:MINT-72596 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:68393|refseq:NP_113918.2|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR005821(Ion transport)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003975(Potassium channel, voltage dependent, Kv4)|interpro:IPR004055(Potassium channel, voltage dependent, Kv4.2)|interpro:IPR024587|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR021645|rcsb pdb:1NN7|rcsb pdb:1S6C|go:"GO:0044853"(plasma membrane raft)|go:"GO:0001508"(action potential)|go:"GO:0005216"(ion channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005250"("A-type (transient outward) potassium channel activity")|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035690"|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR028325|interpro:IPR027359|mint:MINT-373206(identity) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373196(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:dCCK/LfSRScYhsvmD7n6/UDcCDc10116 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 intact-crc:D8A17880CACA3C80|rigid:YlBL7kqCst2YLtsn4VxxiE3c90Y false binding-associated region:407-630(MINT-373207)|tag:?-?(MINT-373210) binding-associated region:1-525(MINT-373197)|tag:?-?(MINT-373200) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62897 uniprotkb:O54824 intact:EBI-7082853|uniprotkb:Q63286|uniprotkb:O08723|uniprotkb:Q99P42|intact:MINT-103596|uniprotkb:P70622 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 psi-mi:kcnd3_rat(display_long)|uniprotkb:Kcnd3(gene name)|psi-mi:Kcnd3(display_short)|uniprotkb:Voltage-gated potassium channel subunit Kv4.3(gene name synonym) psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082894|mint:MINT-72597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-RNO-1296072|reactome:R-RNO-5576894|go:"GO:0005216"(ion channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005250"("A-type (transient outward) potassium channel activity")|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099625"(ventricular cardiac muscle cell membrane repolarization)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003975(Potassium channel, voltage dependent, Kv4)|interpro:IPR004056(Potassium channel, voltage dependent, Kv4.3)|interpro:IPR005821(Ion transport)|interpro:IPR021645|interpro:IPR024587|interpro:IPR027359|interpro:IPR028325|rcsb pdb:2I2R|interpro:IPR011333(BTB/POZ fold)|refseq:NP_113927.2|rgd:68394|refseq:NP_001257892.1|refseq:NP_001257891.1|dip:DIP-29245N|mint:MINT-373298(identity) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373288(identity) - comment:mint|function:"Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:zJN5DkxofoEqmQzUGj9XmQuwDms10116 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 intact-crc:70BCB48651000819|rigid:U7AbGxxEnYRSi0k9N4w76SEx22w false binding-associated region:423-655(MINT-373299)|tag:?-?(MINT-373302) binding-associated region:1-525(MINT-373289)|tag:?-?(MINT-373292) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:Q01815 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7082921|mint:MINT-72601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373265(identity) refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N|mint:MINT-373275(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090 intact-crc:780130A1FD2402E6|rigid:kgHA89rnmB6XmxZPnT+kq07KWQw false tag:?-?(MINT-373269)|binding-associated region:1-525(MINT-373266) tag:?-?(MINT-373279)|binding-associated region:1847-2139(MINT-373276) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:Q01098 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-2314786|ensembl:ENSMUSP00000003351|ensembl:ENSMUSP00000102164 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:nmde3_mouse(display_long)|uniprotkb:Grin2c(gene name)|psi-mi:Grin2c(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2C(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-3(gene name synonym) psi-mi:"MI:0428"(imaging technique) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7082968|mint:MINT-72586 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373160(identity) refseq:NP_034480.2|ensembl:ENSMUSG00000020734(gene)|ensembl:ENSMUST00000003351(transcript)|ensembl:ENSMUST00000106554(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009611"(response to wounding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0033058"(directional locomotion)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|reactome:R-MMU-8849932|reactome:R-MMU-9609736|mint:MINT-373165(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6|comment:homomint|comment:mint taxid:10090(mouse-cerebellum gra)|taxid:10090(Mus musculus) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:HebVX3SlMU9ggutNdrAR04X/fvo10090 intact-crc:ECB302B057E51784|rigid:0GPzRjCKGOcCbe0RvAC8DFuJTpU false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O54824 uniprotkb:Q62645 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-631067|uniprotkb:Q63381|uniprotkb:Q63382|uniprotkb:Q63729|uniprotkb:Q63730|ensembl:ENSRNOP00000028615 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:nmde4_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2D(gene name synonym)|uniprotkb:Grin2d(gene name)|psi-mi:Grin2d(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-4(gene name synonym)|uniprotkb:GluN2D(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7082985|mint:MINT-72588 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373358(identity) rgd:2740|refseq:NP_073634.1|ensembl:ENSRNOG00000021063(gene)|ensembl:ENSRNOT00000028615(transcript)|go:"GO:0001964"(startle response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016595"(glutamate binding)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3OEK|rcsb pdb:3OEL|rcsb pdb:3OEM|rcsb pdb:3OEN|rcsb pdb:4JWY|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|refseq:XP_008757539.1|mint:MINT-373368(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:EI0xEBqUTBpq1D93yQqU4XLHdc810116 intact-crc:705C87FE33AB6114|rigid:jGfpkqc7z7GNoEZaaSFpklm03yE false glutathione s tranferase tag:?-?(MINT-373362)|binding-associated region:1-297(MINT-373359) binding-associated region:839-1323(MINT-373369) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99712 uniprotkb:O54824 intact:EBI-7082607|ensembl:ENSP00000331698|ensembl:ENSP00000381904|ensembl:ENSP00000381905|ensembl:ENSP00000381907|ensembl:ENSP00000381911|ensembl:ENSP00000479100|ensembl:ENSP00000484960|intact:MINT-103775|uniprotkb:Q96L28|uniprotkb:D3DSH5|uniprotkb:Q99446|uniprotkb:O00564 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 psi-mi:kcj15_human(display_long)|uniprotkb:KCNJ15(gene name)|psi-mi:KCNJ15(display_short)|uniprotkb:KCNJ14(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 15(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.2"(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir1.3"(gene name synonym) psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:"MI:0096"(pull down) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7083050|mint:MINT-72593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011527862.1|refseq:XP_011527863.1|ensembl:ENSG00000157551(gene)|ensembl:ENST00000328656(transcript)|ensembl:ENST00000398930(transcript)|ensembl:ENST00000398932(transcript)|ensembl:ENST00000398934(transcript)|ensembl:ENST00000398938(transcript)|ensembl:ENST00000612702(transcript)|ensembl:ENST00000613499(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003270(Potassium channel, inwardly rectifying, Kir1.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-HSA-1296041|reactome:R-HSA-997272|refseq:XP_016883832.1|refseq:XP_016883833.1|refseq:XP_016883834.1|refseq:NP_001263365.1|refseq:NP_733933.1|refseq:NP_001263368.1|refseq:NP_001263366.1|refseq:NP_002234.2|refseq:NP_001263364.1|refseq:NP_001263367.1|refseq:NP_733932.1|refseq:XP_005261032.1|refseq:XP_006724065.1|mint:MINT-373434(identity) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373424(identity) - comment:mint|function:Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/22 2014/10/16 rogid:TiE/A9/tLsonRMg7/KsThkWgr8Q9606 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 intact-crc:4B0750D632332A29|rigid:vHM+Xeu2KtFU4qo9A8/8xBoxbUA false - glutathione s tranferase tag:?-?(MINT-373428)|binding-associated region:1-297(MINT-373425) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:P49655 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-706185|uniprotkb:Q62790 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:kcj10_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 10(gene name synonym)|uniprotkb:ATP-sensitive inward rectifier potassium channel KAB-2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.1"(gene name synonym)|uniprotkb:BIR10(gene name synonym)|uniprotkb:"Brain-specific inwardly rectifying K(+) channel 1"(gene name synonym)|uniprotkb:Kcnj10(gene name)|psi-mi:Kcnj10(display_short)|uniprotkb:Kab-2(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7083008|mint:MINT-72592 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373442(identity) refseq:NP_113790.2|refseq:XP_008767959.1|rgd:61822|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003269(Potassium channel, inwardly rectifying, Kir1.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|refseq:XP_017454263.1|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296067|reactome:R-RNO-997272|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007601"(visual perception)|go:"GO:0007628"(adult walking behavior)|go:"GO:0009637"(response to blue light)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051935"(glutamate reuptake)|go:"GO:0051938"(L-glutamate import)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|mint:MINT-373452(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:ri6d3VbUvSLj12uMiqruQGL09sE10116 intact-crc:1E9B5444A626A3B6|rigid:nMvbHmfzJy8pjiE3IjdjC44YoOc false glutathione s tranferase tag:?-?(MINT-373446)|binding-associated region:1-297(MINT-373443) mutation decreasing interaction:379-379,377-377,378-378(MINT-373453) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:Q01815 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7083069|mint:MINT-72602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373337(identity) refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N|mint:MINT-373347(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090 intact-crc:CF5EC1913087166B|rigid:kgHA89rnmB6XmxZPnT+kq07KWQw false binding-associated region:1-297(MINT-373338)|glutathione s tranferase tag:?-?(MINT-373341) binding-associated region:1847-2139(MINT-373348) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54824 uniprotkb:P35436 intact:EBI-641708|uniprotkb:O70236|uniprotkb:Q3TEM4|uniprotkb:Q8R0G5|uniprotkb:Q5DTR5|uniprotkb:Q9QZP6|ensembl:ENSMUSP00000001792 intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900 psi-mi:il16_mouse(display_long)|uniprotkb:Il16(gene name)|psi-mi:Il16(display_short) psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kurschner et al. (1999) pubmed:10479680|mint:MINT-5211781 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7083098|mint:MINT-72583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034681.2|refseq:XP_006507449.1|refseq:XP_011239983.1|ensembl:ENSMUSG00000001741(gene)|ensembl:ENSMUST00000001792(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:1902565"(positive regulation of neutrophil activation)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR020450|interpro:IPR036034|mint:O54824|reactome:R-MMU-449836|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0090543"(Flemming body)|mint:MINT-373466(identity) refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|mint:MINT-373473(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:homomint|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2005/11/22 2014/10/16 rogid:i4rzjOOqd/moda02EJD7CC5j+5Q10090 rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090 intact-crc:D2D84A3BA9B408F4|rigid:xr/MMz/i0KPsMFbVsM9kIyKsdGE false tag:?-?(MINT-373467) tag:?-?(MINT-373474) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)