#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O35430 uniprotkb:Q00975 intact:EBI-704760 intact:EBI-1055161|uniprotkb:B1AQK5|ensembl:ENSP00000360423 psi-mi:apba1_rat(display_long)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Apba1(gene name)|psi-mi:Apba1(display_short)|uniprotkb:Mint1(gene name synonym)|uniprotkb:X11(gene name synonym) psi-mi:cac1b_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:CACNA1B(gene name)|psi-mi:CACNA1B(display_short)|uniprotkb:CACH5(gene name synonym)|uniprotkb:CACNL1A5(gene name synonym) psi-mi:"MI:0096"(pull down) Maximov et al. (1999) pubmed:10455105|mint:MINT-5211756 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7076778|mint:MINT-59447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620844|refseq:NP_113967.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR030530|mint:O35430|interpro:IPR036034|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:4DBB|rcsb pdb:6KMH|reactome:R-RNO-212676|mint:MINT-372715(identity) refseq:NP_000709.1|refseq:NP_001230741.1|ensembl:ENSG00000148408(gene)|ensembl:ENST00000371372(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR043203|rcsb pdb:2LCM|reactome:R-HSA-112308|mint:MINT-372723(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/06/28 2014/10/16 rogid:ybffWeGU/EFTeYx031rgcwPB2w410116 rogid:R7OVT/57HywIdiczIgCa+cjqifA9606 intact-crc:A23543154D653755|rigid:sOKEFFrbXHlUyiU2plBjVYCxGKE false binding-associated region:647-751(MINT-372716) tag:?-?(MINT-372729)|mutation decreasing interaction:2334-2334(MINT-372727)|binding-associated region:2333-2339(MINT-372724) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14936 uniprotkb:Q02294 intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405 intact:EBI-540038 psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym) psi-mi:cac1b_rat(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:Cacna1b(gene name)|psi-mi:Cacna1b(display_short)|uniprotkb:Cach5(gene name synonym)|uniprotkb:Cacnl1a5(gene name synonym) psi-mi:"MI:0096"(pull down) Maximov et al. (1999) pubmed:10455105|mint:MINT-5211756 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7076808|mint:MINT-59448 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|ensembl:ENSG00000147044(gene)|ensembl:ENST00000378163(transcript)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS|mint:MINT-372673(identity) rgd:628852|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043679"(axon terminus)|go:"GO:0045471"(response to ethanol)|go:"GO:0048265"(response to pain)|interpro:IPR031649|interpro:IPR043203|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:0050804"(modulation of chemical synaptic transmission)|rcsb pdb:4DEX|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR027359|reactome:R-RNO-112308|mint:MINT-372682(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/06/28 2014/10/16 rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606 rogid:hpV4gZ1tOmB6Pqvsry18/tzzxhU10116 intact-crc:C63296AC5668D08D|rigid:t3OezMzogrAcM33DJ70I6d5ZzD0 false binding-associated region:547-742(MINT-372674)|tag:?-?(MINT-372677) binding-associated region:2039-2194(MINT-372683)|tag:?-?(MINT-372688)|mutation decreasing interaction:2334-2334(MINT-372686) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q00975 uniprotkb:O35430 intact:EBI-1055161|uniprotkb:B1AQK5|ensembl:ENSP00000360423 intact:EBI-704760 psi-mi:cac1b_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:CACNA1B(gene name)|psi-mi:CACNA1B(display_short)|uniprotkb:CACH5(gene name synonym)|uniprotkb:CACNL1A5(gene name synonym) psi-mi:apba1_rat(display_long)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Apba1(gene name)|psi-mi:Apba1(display_short)|uniprotkb:Mint1(gene name synonym)|uniprotkb:X11(gene name synonym) psi-mi:"MI:0096"(pull down) Maximov et al. (1999) pubmed:10455105|mint:MINT-5211756 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7076857|mint:MINT-59450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000709.1|refseq:NP_001230741.1|ensembl:ENSG00000148408(gene)|ensembl:ENST00000371372(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR043203|rcsb pdb:2LCM|reactome:R-HSA-112308|mint:MINT-372647(identity) rgd:620844|refseq:NP_113967.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR030530|mint:O35430|interpro:IPR036034|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:4DBB|rcsb pdb:6KMH|reactome:R-RNO-212676|mint:MINT-372637(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/06/28 2014/10/16 rogid:R7OVT/57HywIdiczIgCa+cjqifA9606 rogid:ybffWeGU/EFTeYx031rgcwPB2w410116 intact-crc:5E4EFA92B745CFBF|rigid:sOKEFFrbXHlUyiU2plBjVYCxGKE false binding-associated region:2333-2339(MINT-372648)|mutation decreasing interaction:2334-2334(MINT-372651) binding-associated region:647-751(MINT-372638)|tag:?-?(MINT-372642) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35430 uniprotkb:Q02294 intact:EBI-704760 intact:EBI-540038 psi-mi:apba1_rat(display_long)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Apba1(gene name)|psi-mi:Apba1(display_short)|uniprotkb:Mint1(gene name synonym)|uniprotkb:X11(gene name synonym) psi-mi:cac1b_rat(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:Cacna1b(gene name)|psi-mi:Cacna1b(display_short)|uniprotkb:Cach5(gene name synonym)|uniprotkb:Cacnl1a5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Maximov et al. (1999) pubmed:10455105|mint:MINT-5211756 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7076897|mint:MINT-59449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620844|refseq:NP_113967.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR030530|mint:O35430|interpro:IPR036034|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:4DBB|rcsb pdb:6KMH|reactome:R-RNO-212676|mint:MINT-372699(identity) rgd:628852|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043679"(axon terminus)|go:"GO:0045471"(response to ethanol)|go:"GO:0048265"(response to pain)|interpro:IPR031649|interpro:IPR043203|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:0050804"(modulation of chemical synaptic transmission)|rcsb pdb:4DEX|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR027359|reactome:R-RNO-112308|mint:MINT-372707(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1E|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2005/06/28 2014/10/16 rogid:ybffWeGU/EFTeYx031rgcwPB2w410116 rogid:hpV4gZ1tOmB6Pqvsry18/tzzxhU10116 intact-crc:23286EC89BEAC5AE|rigid:g5i95Lc9BgHASJP9C0x8YqmdgM8 false binding-associated region:647-751(MINT-372700) - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35430 uniprotkb:Q00975 intact:EBI-704760 intact:EBI-1055161|uniprotkb:B1AQK5|ensembl:ENSP00000360423 psi-mi:apba1_rat(display_long)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Apba1(gene name)|psi-mi:Apba1(display_short)|uniprotkb:Mint1(gene name synonym)|uniprotkb:X11(gene name synonym) psi-mi:cac1b_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:CACNA1B(gene name)|psi-mi:CACNA1B(display_short)|uniprotkb:CACH5(gene name synonym)|uniprotkb:CACNL1A5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Maximov et al. (1999) pubmed:10455105|mint:MINT-5211756 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7076926|mint:MINT-59446 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620844|refseq:NP_113967.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR030530|mint:O35430|interpro:IPR036034|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:4DBB|rcsb pdb:6KMH|reactome:R-RNO-212676|mint:MINT-372740(identity) refseq:NP_000709.1|refseq:NP_001230741.1|ensembl:ENSG00000148408(gene)|ensembl:ENST00000371372(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR043203|rcsb pdb:2LCM|reactome:R-HSA-112308|mint:MINT-372750(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/06/28 2014/10/16 rogid:ybffWeGU/EFTeYx031rgcwPB2w410116 rogid:R7OVT/57HywIdiczIgCa+cjqifA9606 intact-crc:DDAAFC17DB2A29F5|rigid:sOKEFFrbXHlUyiU2plBjVYCxGKE false binding-associated region:647-751(MINT-372741)|tag:?-?(MINT-372745) mutation decreasing interaction:2338-2338(MINT-372754)|binding-associated region:2333-2339(MINT-372751)|tag:?-?(MINT-372756) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)