#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q24218 uniprotkb:Q9VI13 intact:EBI-74727 intact:EBI-74826|intact:EBI-123979|intact:EBI-466309|uniprotkb:Q24190|uniprotkb:Q24213|ensemblmetazoa:FBpp0081211|ensemblmetazoa:FBpp0081212|ensemblmetazoa:FBpp0081213|ensemblmetazoa:FBpp0306606|ensemblmetazoa:FBpp0306611 psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:pak_drome(display_long)|uniprotkb:Pak(gene name)|psi-mi:Pak(display_short)|uniprotkb:DPAK(gene name synonym)|uniprotkb:Dpak1(gene name synonym)|uniprotkb:CG10295(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hing et al. (1999) pubmed:10399914|mint:MINT-5211650 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7053857|mint:MINT-65944 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860|mint:MINT-370743(identity) flybase:FBgn0267698|refseq:NP_001262309.1|refseq:NP_001262313.1|refseq:NP_524681.1|refseq:NP_731073.1|refseq:NP_731074.1|ensemblmetazoa:FBgn0267698(gene)|ensemblmetazoa:FBtr0081714(transcript)|ensemblmetazoa:FBtr0081715(transcript)|ensemblmetazoa:FBtr0081716(transcript)|ensemblmetazoa:FBtr0334539(transcript)|ensemblmetazoa:FBtr0334544(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019991"(septate junction assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:MINT-370747(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/10/12 2021/06/18 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 rogid:B88kI/CaRk7fc0eQ5+Y4jk4zWwc7227 intact-crc:AF4AA75F13A74B28|rigid:RomjW24LZ1nALWWwsYaUA7gVbN0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VI13 uniprotkb:Q24218 intact:EBI-74826|intact:EBI-123979|intact:EBI-466309|uniprotkb:Q24190|uniprotkb:Q24213|ensemblmetazoa:FBpp0081211|ensemblmetazoa:FBpp0081212|ensemblmetazoa:FBpp0081213|ensemblmetazoa:FBpp0306606|ensemblmetazoa:FBpp0306611 intact:EBI-74727 psi-mi:pak_drome(display_long)|uniprotkb:Pak(gene name)|psi-mi:Pak(display_short)|uniprotkb:DPAK(gene name synonym)|uniprotkb:Dpak1(gene name synonym)|uniprotkb:CG10295(orf name) psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:"MI:0018"(two hybrid) Hing et al. (1999) pubmed:10399914|mint:MINT-5211650 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7053899|mint:MINT-65943 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0267698|refseq:NP_001262309.1|refseq:NP_001262313.1|refseq:NP_524681.1|refseq:NP_731073.1|refseq:NP_731074.1|ensemblmetazoa:FBgn0267698(gene)|ensemblmetazoa:FBtr0081714(transcript)|ensemblmetazoa:FBtr0081715(transcript)|ensemblmetazoa:FBtr0081716(transcript)|ensemblmetazoa:FBtr0334539(transcript)|ensemblmetazoa:FBtr0334544(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019991"(septate junction assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:MINT-370767(identity) flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860|mint:MINT-370756(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A F1B|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/10/12 2021/06/18 rogid:B88kI/CaRk7fc0eQ5+Y4jk4zWwc7227 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 intact-crc:01D15E7F22CC0D51|rigid:RomjW24LZ1nALWWwsYaUA7gVbN0 false binding-associated region:9-14(MINT-370768)|tag:?-?(MINT-370774)|mutation decreasing interaction:9-9,14-14(MINT-370771) tag:?-?(MINT-370762)|mutation decreasing interaction:151-151(MINT-370760)|binding-associated region:117-171(MINT-370757) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)