#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06789	uniprotkb:Q12824-1	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015639|mint:MINT-68789	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368777(identity)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368786(identity)	-	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/11/07	2014/10/16	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:2A073F9E400D7431|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	tag:?-?(MINT-368780)|binding-associated region:147-657(MINT-368778)	binding-associated region:125-385(MINT-368787)|tag:?-?(MINT-368789)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06789	uniprotkb:Q12824-1	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015745|mint:MINT-68798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368823(identity)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368830(identity)	-	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/11/07	2014/10/16	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:5219843471A69887|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	tag:?-?(MINT-368824)	tag:?-?(MINT-368833)|binding-associated region:184-247(MINT-368831)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12824-1	uniprotkb:P06789	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015723|mint:MINT-68797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368625(identity)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368618(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/11/07	2014/10/16	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	intact-crc:8628E160CD96F80F|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	binding-associated region:184-377(MINT-368626)|tag:?-?(MINT-368628)	tag:?-?(MINT-368619)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12824-1	uniprotkb:P06789	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015767|mint:MINT-68799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368606(identity)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368599(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/11/07	2014/10/16	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	intact-crc:36DE96FB8BD55666|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	tag:?-?(MINT-368609)|binding-associated region:184-331(MINT-368607)	tag:?-?(MINT-368600)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12824-1	uniprotkb:P06789	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015789|mint:MINT-68800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368813(identity)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368798(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	figure legend:F6B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/11/07	2014/10/16	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	intact-crc:F7DE110F130DF506|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	tag:?-?(MINT-368814)	tag:?-?(MINT-368807)|mutation decreasing interaction:305-305,395-395,396-396,418-418,419-419,225-225,226-226(MINT-368799)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12824-1	uniprotkb:P06789	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015850|mint:MINT-68791	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368703(identity)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368696(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	intact-crc:963052B44B0EE8A2|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	glutathione s tranferase tag:?-?(MINT-368704)	binding-associated region:147-657(MINT-368697)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06789	uniprotkb:Q12824-1	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015920|mint:MINT-68793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368730(identity)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368737(identity)	-	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:A6B8CFAC0AD3C069|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	binding-associated region:147-444(MINT-368731)	glutathione s tranferase tag:?-?(MINT-368738)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06789	uniprotkb:Q12824-1	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015901|mint:MINT-68792	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368713(identity)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368720(identity)	-	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:A136365ACD8DCEAC|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	binding-associated region:1-444(MINT-368714)	glutathione s tranferase tag:?-?(MINT-368721)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12824-1	uniprotkb:P03116	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	intact:EBI-7015985|intact:MINT-91530|uniprotkb:Q9WMH1	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:ve1_bpv1(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:337052(bpv1)|taxid:337052(Bovine papillomavirus type 1)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7016010|mint:MINT-68795	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368752(identity)	mint:P03116|refseq:NP_056739.1|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|rcsb pdb:1F08|rcsb pdb:1KSX|rcsb pdb:1KSY|rcsb pdb:2GXA|rcsb pdb:2V9P|rcsb pdb:5A9K|dip:DIP-40903N|mint:MINT-368747(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	figure legend:F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	rogid:7Fn7e9YGTrgaAWIHaZqHEKhZtfE337052	intact-crc:537E994121782720|rigid:2ZsXJTR5cB6Tpj7eiurvGBfsLeU	false	glutathione s tranferase tag:?-?(MINT-368753)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04014	uniprotkb:Q12824-1	intact:EBI-7014446|intact:MINT-95113	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	psi-mi:ve1_hpv11(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:10580(hpv11)|taxid:10580(Human papillomavirus type 11)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7015939|mint:MINT-68794	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P04014|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0034214"(protein hexamerization)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368762(identity)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368767(identity)	-	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:Xg3fdEVHcqOpmqe7MPf9EXciD3s10580	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:93E510C36F417BCD|rigid:2gn4Ll9XmoiIKYKv2i2c19Q/+qY	false	-	glutathione s tranferase tag:?-?(MINT-368768)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06789	uniprotkb:Q12824-1	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7016059|mint:MINT-68801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368639(identity)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368649(identity)	-	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F6C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:4A598D0FB05D7A15|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	mutation decreasing interaction:305-305,224-225,394-395,417-418(MINT-368640)	glutathione s tranferase tag:?-?(MINT-368650)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12824-1	uniprotkb:P06789	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7016286|mint:MINT-68796	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368669(identity)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368662(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-c33a)|taxid:9606(Homo sapiens epihelial cervix carcinoma cells)	-	2005/11/07	2014/10/16	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	intact-crc:883DD9286FF24133|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	ha tag:?-?(MINT-368670)	flag tag:?-?(MINT-368663)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12824-1	uniprotkb:P06789	intact:EBI-7015645|intact:MINT-94978|ensembl:ENSP00000479330|ensembl:ENSP00000494049	intact:EBI-7015660|intact:MINT-94927|uniprotkb:Q84181	psi-mi:q12824-1(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:INI1A(isoform synonym)	psi-mi:ve1_hpv18(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (1999)	pubmed:10365963|mint:MINT-5211547	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7016304|mint:MINT-69678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|intact:EBI-358419(isoform-parent)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|mint:MINT-368686(identity)	mint:P06789|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0019079"(viral genome replication)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1R9W|rcsb pdb:1TUE|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|refseq:NP_040312.1|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|mint:MINT-368679(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins|comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-c33a)|taxid:9606(Homo sapiens epihelial cervix carcinoma cells)	-	2005/11/07	2014/10/16	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	rogid:vEIUDcd+5AP1vg6WiMUJkrKmcrA333761	intact-crc:4F77C221BFF51BCE|rigid:NmM2ASvBN0+Fi5IkmlHuBAQMq4Y	false	ha tag:?-?(MINT-368687)	flag tag:?-?(MINT-368680)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)