#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q63226 uniprotkb:Q62696 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-389325 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6988692|mint:MINT-69594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-1746896(identity) rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N|mint:MINT-1746908(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:1377E559003099A8|rigid:J5P8lzegDr43DNfD2OuHREWzQKk false mutation decreasing interaction:1002-1007(MINT-1746900)|binding-associated region:852-1007(MINT-1746897)|tag:?-?(MINT-1746902) tag:?-?(MINT-1746913)|binding-associated region:130-662(MINT-1746909) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63226 uniprotkb:Q63622 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6988771|mint:MINT-69595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-367162(identity) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:MINT-367174(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:338EDF802F5A990E|rigid:XDklDGHtbct7fAWiCXfCDyXLmw0 false binding-associated region:852-1007(MINT-367163)|tag:?-?(MINT-367168)|mutation decreasing interaction:1002-1007(MINT-367166) binding-associated region:83-421(MINT-367175)|tag:?-?(MINT-367178) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63226 uniprotkb:P31016 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6988809|mint:MINT-69596 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-1621596(identity) go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N|mint:MINT-1621606(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|comment:Stronger interaction with the region encompassing the three PDZ domains|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116 intact-crc:7772B5B08EB928C5|rigid:ar5DENtclsrsBOd6nSiMFNfuS+Q false tag:?-?(MINT-1621600)|binding-associated region:852-1007(MINT-1621597) binding-associated region:158-314(MINT-1621607)|tag:?-?(MINT-1621610) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62640 uniprotkb:Q63622 intact:EBI-6988856|uniprotkb:Q63225|intact:MINT-257777 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:grid1_rat(display_long)|uniprotkb:Grid1(gene name)|psi-mi:Grid1(display_short) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6988852|mint:MINT-69597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0035176"(social behavior)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|rgd:68366|interpro:IPR019594|refseq:NP_077354.1|interpro:IPR028082|rcsb pdb:6KSP|rcsb pdb:6KSS|mint:MINT-367189(identity) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:MINT-367199(identity) - function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/16 2014/10/16 rogid:Avhdy9xXioD+uqXoL83gw1dp9gk10116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:98CEDD9CA3B06184|rigid:YHBBZe1XkDkgg3WJdDsebMk/XQU false tag:?-?(MINT-367193)|binding-associated region:851-1009(MINT-367190) binding-associated region:83-421(IPR001478)|tag:?-?(MINT-367204) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63226 uniprotkb:Q63622 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6989076|mint:MINT-69598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-367215(identity) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:MINT-367224(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:EE020E53034BF415|rigid:XDklDGHtbct7fAWiCXfCDyXLmw0 false tag:?-?(MINT-367218)|mutation decreasing interaction:1005-1005(MINT-367216) tag:?-?(MINT-367225) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q63226 uniprotkb:Q63622 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6989220|mint:MINT-69599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-367236(identity) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:MINT-367245(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:35BC9633A9D1AABB|rigid:XDklDGHtbct7fAWiCXfCDyXLmw0 false tag:?-?(MINT-367239)|mutation decreasing interaction:1005-1005(MINT-367237) tag:?-?(MINT-367246) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0708"(monoclonal antibody immunostaining) uniprotkb:Q63226 uniprotkb:Q63622 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6989273|mint:MINT-69602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-1579406(identity) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:MINT-1579411(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:575DDFE936D331D6|rigid:XDklDGHtbct7fAWiCXfCDyXLmw0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q63226 uniprotkb:Q63622 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6989332|mint:MINT-69600 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-1707071(identity) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:MINT-1707076(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:80ECCA9E564B0B4B|rigid:XDklDGHtbct7fAWiCXfCDyXLmw0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q63226 uniprotkb:Q63622 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6989386|mint:MINT-69601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-1639987(identity) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:MINT-1639992(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:630384E2BE7AE958|rigid:XDklDGHtbct7fAWiCXfCDyXLmw0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q63226 uniprotkb:Q63622 intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641 intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939 psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Roche et al. (1999) pubmed:10234023|mint:MINT-5211432 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6989405|mint:MINT-69603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N|mint:MINT-1767560(identity) rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:MINT-1767565(identity) - comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus) - 2005/11/16 2014/10/16 rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116 rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116 intact-crc:7F72A9F33FB7B10E|rigid:XDklDGHtbct7fAWiCXfCDyXLmw0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)