#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P29310	uniprotkb:Q8IPH9	intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137	intact:EBI-142379|uniprotkb:O61564|uniprotkb:Q95SL3|uniprotkb:Q9VLZ4|uniprotkb:Q5BIJ6|ensemblmetazoa:FBpp0303540|ensemblmetazoa:FBpp0303542	psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym)	psi-mi:slob_drome(display_long)|uniprotkb:Slob(gene name)|psi-mi:Slob(display_short)|uniprotkb:CG43756(orf name)	psi-mi:"MI:0018"(two hybrid)	Zhou et al. (1999)	pubmed:10230800	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529084	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399	flybase:FBgn0264087|refseq:NP_001033881.1|refseq:NP_001188710.1|refseq:NP_477349.1|refseq:NP_723292.1|refseq:NP_723293.1|ensemblmetazoa:FBgn0264087(gene)|ensemblmetazoa:FBtr0330697(transcript)|ensemblmetazoa:FBtr0330699(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042594"(response to starvation)|go:"GO:0043271"(negative regulation of ion transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|interpro:IPR011009(Protein kinase-like)	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227	rogid:l3TJmhm+mVIuo4XzeG7+wVRY1YI7227	intact-crc:B32EBF089A45D35C|rigid:UMP1D2cgvFyw9DZ5tsIZrEloZUE	false	-	-	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:P29310	uniprotkb:Q03720	intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137	intact:EBI-426805|uniprotkb:Q24369|uniprotkb:Q59DU0|uniprotkb:Q59DU1|uniprotkb:Q59DU2|uniprotkb:Q59DU3|uniprotkb:Q59DU4|uniprotkb:Q59DU5|uniprotkb:Q59DU6|uniprotkb:Q59DU7|uniprotkb:Q59DU8|uniprotkb:Q59DU9|uniprotkb:Q59DV0|uniprotkb:Q59DV1|uniprotkb:Q59DV2|uniprotkb:Q7KS13|uniprotkb:Q86NK5|uniprotkb:Q8IMV9|uniprotkb:Q9TWA1|uniprotkb:Q9VC51|uniprotkb:A4V3D4|uniprotkb:Q24384|uniprotkb:Q24385|uniprotkb:Q7JP74|ensemblmetazoa:FBpp0100095	psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym)	psi-mi:slo_drome(display_long)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:slo(gene name)|psi-mi:slo(display_short)|uniprotkb:CG10693(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhou et al. (1999)	pubmed:10230800	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529090	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399	refseq:NP_001014660.1|refseq:NP_001014661.2|refseq:NP_001014662.1|refseq:NP_001014663.1|refseq:NP_001014664.1|refseq:NP_524486.2|refseq:NP_733029.1|refseq:NP_996289.1|flybase:FBgn0003429|refseq:NP_001014651.1|refseq:NP_001014652.1|refseq:NP_001014653.1|refseq:NP_001014654.1|refseq:NP_001014655.1|refseq:NP_001014656.1|refseq:NP_001014657.1|refseq:NP_001014658.1|refseq:NP_001014659.1|ensemblmetazoa:FBgn0003429(gene)|ensemblmetazoa:FBtr0100635(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0048512"(circadian behavior)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-DME-1300642	-	-	-	figure legend:Fig 4	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/04/12	2014/10/16	rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227	rogid:RJ1d6NqNTG7hU0pHboPIRa1PesE7227	intact-crc:4A64D0162E9E293F|rigid:PCsMuQNmttfn/W/B1UxRWBa9wqI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29310	uniprotkb:Q8IPH9	intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137	intact:EBI-142379|uniprotkb:O61564|uniprotkb:Q95SL3|uniprotkb:Q9VLZ4|uniprotkb:Q5BIJ6|ensemblmetazoa:FBpp0303540|ensemblmetazoa:FBpp0303542	psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym)	psi-mi:slob_drome(display_long)|uniprotkb:Slob(gene name)|psi-mi:Slob(display_short)|uniprotkb:CG43756(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhou et al. (1999)	pubmed:10230800	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529090	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399	flybase:FBgn0264087|refseq:NP_001033881.1|refseq:NP_001188710.1|refseq:NP_477349.1|refseq:NP_723292.1|refseq:NP_723293.1|ensemblmetazoa:FBgn0264087(gene)|ensemblmetazoa:FBtr0330697(transcript)|ensemblmetazoa:FBtr0330699(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042594"(response to starvation)|go:"GO:0043271"(negative regulation of ion transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|interpro:IPR011009(Protein kinase-like)	-	-	-	figure legend:Fig 4	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/04/12	2014/10/16	rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227	rogid:l3TJmhm+mVIuo4XzeG7+wVRY1YI7227	intact-crc:4A64D0162E9E293F|rigid:PCsMuQNmttfn/W/B1UxRWBa9wqI	false	-	mutation disrupting interaction strength:54-54,79-79|mutation decreasing interaction strength:54-54	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29310	uniprotkb:Q03720	intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137	intact:EBI-426805|uniprotkb:Q24369|uniprotkb:Q59DU0|uniprotkb:Q59DU1|uniprotkb:Q59DU2|uniprotkb:Q59DU3|uniprotkb:Q59DU4|uniprotkb:Q59DU5|uniprotkb:Q59DU6|uniprotkb:Q59DU7|uniprotkb:Q59DU8|uniprotkb:Q59DU9|uniprotkb:Q59DV0|uniprotkb:Q59DV1|uniprotkb:Q59DV2|uniprotkb:Q7KS13|uniprotkb:Q86NK5|uniprotkb:Q8IMV9|uniprotkb:Q9TWA1|uniprotkb:Q9VC51|uniprotkb:A4V3D4|uniprotkb:Q24384|uniprotkb:Q24385|uniprotkb:Q7JP74|ensemblmetazoa:FBpp0100095	psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym)	psi-mi:slo_drome(display_long)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:slo(gene name)|psi-mi:slo(display_short)|uniprotkb:CG10693(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhou et al. (1999)	pubmed:10230800	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529099	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399	refseq:NP_001014660.1|refseq:NP_001014661.2|refseq:NP_001014662.1|refseq:NP_001014663.1|refseq:NP_001014664.1|refseq:NP_524486.2|refseq:NP_733029.1|refseq:NP_996289.1|flybase:FBgn0003429|refseq:NP_001014651.1|refseq:NP_001014652.1|refseq:NP_001014653.1|refseq:NP_001014654.1|refseq:NP_001014655.1|refseq:NP_001014656.1|refseq:NP_001014657.1|refseq:NP_001014658.1|refseq:NP_001014659.1|ensemblmetazoa:FBgn0003429(gene)|ensemblmetazoa:FBtr0100635(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0048512"(circadian behavior)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-DME-1300642	-	-	-	stimulant:The RQED1 fly line with constitutively active rat CaMKII increased interaction between SLOB and 14-3-3-ZETA.|inhibition:The ala2 fly line which expresses a peptide inhibitor of CaMKII decreased the interaction between SLOB and 14-3-3-ZETA.	taxid:7227(drome-head)|taxid:7227(Drosophila melanogaster)	-	2005/04/12	2014/10/16	rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227	rogid:RJ1d6NqNTG7hU0pHboPIRa1PesE7227	intact-crc:FBA21D9751EFB21C|rigid:PCsMuQNmttfn/W/B1UxRWBa9wqI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29310	uniprotkb:Q8IPH9	intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137	intact:EBI-142379|uniprotkb:O61564|uniprotkb:Q95SL3|uniprotkb:Q9VLZ4|uniprotkb:Q5BIJ6|ensemblmetazoa:FBpp0303540|ensemblmetazoa:FBpp0303542	psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym)	psi-mi:slob_drome(display_long)|uniprotkb:Slob(gene name)|psi-mi:Slob(display_short)|uniprotkb:CG43756(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhou et al. (1999)	pubmed:10230800	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529099	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399	flybase:FBgn0264087|refseq:NP_001033881.1|refseq:NP_001188710.1|refseq:NP_477349.1|refseq:NP_723292.1|refseq:NP_723293.1|ensemblmetazoa:FBgn0264087(gene)|ensemblmetazoa:FBtr0330697(transcript)|ensemblmetazoa:FBtr0330699(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042594"(response to starvation)|go:"GO:0043271"(negative regulation of ion transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|interpro:IPR011009(Protein kinase-like)	-	-	-	stimulant:The RQED1 fly line with constitutively active rat CaMKII increased interaction between SLOB and 14-3-3-ZETA.|inhibition:The ala2 fly line which expresses a peptide inhibitor of CaMKII decreased the interaction between SLOB and 14-3-3-ZETA.	taxid:7227(drome-head)|taxid:7227(Drosophila melanogaster)	-	2005/04/12	2014/10/16	rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227	rogid:l3TJmhm+mVIuo4XzeG7+wVRY1YI7227	intact-crc:FBA21D9751EFB21C|rigid:PCsMuQNmttfn/W/B1UxRWBa9wqI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29310	uniprotkb:Q8IPH9	intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137	intact:EBI-142379|uniprotkb:O61564|uniprotkb:Q95SL3|uniprotkb:Q9VLZ4|uniprotkb:Q5BIJ6|ensemblmetazoa:FBpp0303540|ensemblmetazoa:FBpp0303542	psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym)	psi-mi:slob_drome(display_long)|uniprotkb:Slob(gene name)|psi-mi:Slob(display_short)|uniprotkb:CG43756(orf name)	psi-mi:"MI:0096"(pull down)	Zhou et al. (1999)	pubmed:10230800	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399	flybase:FBgn0264087|refseq:NP_001033881.1|refseq:NP_001188710.1|refseq:NP_477349.1|refseq:NP_723292.1|refseq:NP_723293.1|ensemblmetazoa:FBgn0264087(gene)|ensemblmetazoa:FBtr0330697(transcript)|ensemblmetazoa:FBtr0330699(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042594"(response to starvation)|go:"GO:0043271"(negative regulation of ion transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|interpro:IPR011009(Protein kinase-like)	-	-	-	comment:There is one other place where CaMKII can cause phosphorylation.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/04/12	2018/03/15	rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227	rogid:l3TJmhm+mVIuo4XzeG7+wVRY1YI7227	intact-crc:F515E38C0CC41984|rigid:UMP1D2cgvFyw9DZ5tsIZrEloZUE	false	-	mutation decreasing interaction strength:54-54,79-79|O-phospho-L-serine:54-54,79-79|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)