#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P27799	uniprotkb:Q8JZS0	intact:EBI-6982010|ensembl:ENSCAFP00000023174|ensembl:ENSCAFP00040040723|intact:MINT-91226	intact:EBI-770029|ensembl:ENSMUSP00000020057	psi-mi:s6a12_canlf(display_long)|uniprotkb:SLC6A12(gene name)|psi-mi:SLC6A12(display_short)|uniprotkb:"Na(+)/Cl(-) betaine/GABA transporter"(gene name synonym)|uniprotkb:Solute carrier family 6 member 12(gene name synonym)	psi-mi:lin7a_mouse(display_long)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Lin7a(gene name)|psi-mi:Lin7a(display_short)|uniprotkb:Mals1(gene name synonym)|uniprotkb:Veli1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Perego et al. (1999)	pubmed:10228153|mint:MINT-5211416	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6982045|mint:MINT-60063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005636741.1|refseq:XP_005636742.1|refseq:XP_005636743.1|refseq:XP_005636744.1|refseq:XP_005636745.1|refseq:XP_013963726.1|refseq:XP_013963727.1|ensembl:ENSCAFG00000015756(gene)|ensembl:ENSCAFG00040024982(gene)|ensembl:ENSCAFT00000024973(transcript)|ensembl:ENSCAFT00040046662(transcript)|go:"GO:0005332"("gamma-aminobutyric acid:sodium symporter activity")|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0043005"(neuron projection)|interpro:IPR000175("Sodium:neurotransmitter symporter")|reactome:R-CFA-888593|interpro:IPR002983("Sodium:neurotransmitter symporter, betaine")|interpro:IPR037272|reactome:R-CFA-352230|reactome:R-CFA-442660|reactome:R-CFA-71288|refseq:NP_001003322.1|mint:MINT-366859(identity)	refseq:NP_001034443.1|ensembl:ENSMUSG00000019906(gene)|ensembl:ENSMUST00000020057(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q8JZS0|reactome:R-MMU-212676|mint:MINT-366850(identity)	-	comment:mint|function:Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1B|comment:the authors also used Lin-7 from C. elegans|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/05	2014/10/16	rogid:2rPjB6JirgC2GXsPtAVd3n+unLw9615	rogid:WE2wsFc8aJ7M4lPbTJe4T4uquig10090	intact-crc:9B010E3B6DCBDFF1|rigid:HRcdbwpoiWTg8pH41hYOO51zXlk	false	binding-associated region:609-614(MINT-366860)	tag:?-?(MINT-366854)|binding-associated region:108-190(MINT-366851)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P27799	uniprotkb:Q8JZS0	intact:EBI-6982010|ensembl:ENSCAFP00000023174|ensembl:ENSCAFP00040040723|intact:MINT-91226	intact:EBI-770029|ensembl:ENSMUSP00000020057	psi-mi:s6a12_canlf(display_long)|uniprotkb:SLC6A12(gene name)|psi-mi:SLC6A12(display_short)|uniprotkb:"Na(+)/Cl(-) betaine/GABA transporter"(gene name synonym)|uniprotkb:Solute carrier family 6 member 12(gene name synonym)	psi-mi:lin7a_mouse(display_long)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Lin7a(gene name)|psi-mi:Lin7a(display_short)|uniprotkb:Mals1(gene name synonym)|uniprotkb:Veli1(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	Perego et al. (1999)	pubmed:10228153|mint:MINT-5211416	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-6982136|mint:MINT-60065	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005636741.1|refseq:XP_005636742.1|refseq:XP_005636743.1|refseq:XP_005636744.1|refseq:XP_005636745.1|refseq:XP_013963726.1|refseq:XP_013963727.1|ensembl:ENSCAFG00000015756(gene)|ensembl:ENSCAFG00040024982(gene)|ensembl:ENSCAFT00000024973(transcript)|ensembl:ENSCAFT00040046662(transcript)|go:"GO:0005332"("gamma-aminobutyric acid:sodium symporter activity")|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0043005"(neuron projection)|interpro:IPR000175("Sodium:neurotransmitter symporter")|reactome:R-CFA-888593|interpro:IPR002983("Sodium:neurotransmitter symporter, betaine")|interpro:IPR037272|reactome:R-CFA-352230|reactome:R-CFA-442660|reactome:R-CFA-71288|refseq:NP_001003322.1|mint:MINT-366881(identity)	refseq:NP_001034443.1|ensembl:ENSMUSG00000019906(gene)|ensembl:ENSMUST00000020057(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q8JZS0|reactome:R-MMU-212676|mint:MINT-366873(identity)	-	comment:mint|function:Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:The LIN7-mediated interaction is responsable for the cell surface stability of wild-type BGT|figure legend:F4 F5 F6|comment:homomint|comment:mint	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2005/07/05	2014/10/16	rogid:2rPjB6JirgC2GXsPtAVd3n+unLw9615	rogid:WE2wsFc8aJ7M4lPbTJe4T4uquig10090	intact-crc:2213009A3E1D2C86|rigid:HRcdbwpoiWTg8pH41hYOO51zXlk	false	binding-associated region:609-614(MINT-366882)	binding-associated region:108-190(MINT-366874)	-	-	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:P27799	uniprotkb:Q8JZS0	intact:EBI-6982010|ensembl:ENSCAFP00000023174|ensembl:ENSCAFP00040040723|intact:MINT-91226	intact:EBI-770029|ensembl:ENSMUSP00000020057	psi-mi:s6a12_canlf(display_long)|uniprotkb:SLC6A12(gene name)|psi-mi:SLC6A12(display_short)|uniprotkb:"Na(+)/Cl(-) betaine/GABA transporter"(gene name synonym)|uniprotkb:Solute carrier family 6 member 12(gene name synonym)	psi-mi:lin7a_mouse(display_long)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Lin7a(gene name)|psi-mi:Lin7a(display_short)|uniprotkb:Mals1(gene name synonym)|uniprotkb:Veli1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Perego et al. (1999)	pubmed:10228153|mint:MINT-5211416	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6982166|mint:MINT-60064	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005636741.1|refseq:XP_005636742.1|refseq:XP_005636743.1|refseq:XP_005636744.1|refseq:XP_005636745.1|refseq:XP_013963726.1|refseq:XP_013963727.1|ensembl:ENSCAFG00000015756(gene)|ensembl:ENSCAFG00040024982(gene)|ensembl:ENSCAFT00000024973(transcript)|ensembl:ENSCAFT00040046662(transcript)|go:"GO:0005332"("gamma-aminobutyric acid:sodium symporter activity")|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0043005"(neuron projection)|interpro:IPR000175("Sodium:neurotransmitter symporter")|reactome:R-CFA-888593|interpro:IPR002983("Sodium:neurotransmitter symporter, betaine")|interpro:IPR037272|reactome:R-CFA-352230|reactome:R-CFA-442660|reactome:R-CFA-71288|refseq:NP_001003322.1|mint:MINT-366903(identity)	refseq:NP_001034443.1|ensembl:ENSMUSG00000019906(gene)|ensembl:ENSMUST00000020057(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q8JZS0|reactome:R-MMU-212676|mint:MINT-366896(identity)	-	comment:mint|function:Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1D|comment:homomint|comment:mint	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2005/07/05	2014/10/16	rogid:2rPjB6JirgC2GXsPtAVd3n+unLw9615	rogid:WE2wsFc8aJ7M4lPbTJe4T4uquig10090	intact-crc:DCA96BE18CA0D704|rigid:HRcdbwpoiWTg8pH41hYOO51zXlk	false	binding-associated region:609-614(MINT-366904)	binding-associated region:108-190(MINT-366897)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)