#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P23572	uniprotkb:Q9I7I0	intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641	intact:EBI-150964|uniprotkb:O96718|uniprotkb:Q9TYG8|ensemblmetazoa:FBpp0084103|ensemblmetazoa:FBpp0306645	psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name)	psi-mi:ccnb3_drome(display_long)|uniprotkb:CycB3(gene name)|psi-mi:CycB3(display_short)|uniprotkb:CG5814(orf name)	psi-mi:"MI:0019"(coimmunoprecipitation)	Jacobs et al. (1998)	pubmed:9851980	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-396404	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166	refseq:NP_651303.2|flybase:FBgn0015625|refseq:NP_001262934.1|dip:DIP-22205N|ensemblmetazoa:FBgn0015625(gene)|ensemblmetazoa:FBtr0084728(transcript)|ensemblmetazoa:FBtr0334578(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q9I7I0	-	-	-	-	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2004/07/28	2014/10/16	rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227	rogid:x00iO2ghcNgpERCKftXiPiDv+Is7227	intact-crc:2C06CEEE3188CE0A|rigid:SWu3ilYDeItFoK8Frfhasbhz8u0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23572	uniprotkb:P20439	intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641	intact:EBI-190039|uniprotkb:Q0E8Y2|uniprotkb:Q8MME2|uniprotkb:Q9I7V2|uniprotkb:Q9TYH6|uniprotkb:Q9TYH7|uniprotkb:Q9V3F4|ensemblmetazoa:FBpp0071822	psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name)	psi-mi:ccnb_drome(display_long)|uniprotkb:CycB(gene name)|psi-mi:CycB(display_short)|uniprotkb:CG3510(orf name)	psi-mi:"MI:0019"(coimmunoprecipitation)	Jacobs et al. (1998)	pubmed:9851980	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-396404	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166	refseq:NP_726245.2|refseq:NP_726244.1|refseq:NP_726246.1|refseq:NP_726247.1|flybase:FBgn0000405|ensemblmetazoa:FBgn0000405(gene)|ensemblmetazoa:FBtr0071911(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0051233"(spindle midzone)|go:"GO:0061952"(midbody abscission)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P20439|reactome:R-DME-174048|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166	-	-	-	-	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2004/07/28	2014/10/16	rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227	rogid:189MafBrFMpT06ZsFFwvx1UWPHw7227	intact-crc:2C06CEEE3188CE0A|rigid:SWu3ilYDeItFoK8Frfhasbhz8u0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23572	uniprotkb:Q9I7I0	intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641	intact:EBI-150964|uniprotkb:O96718|uniprotkb:Q9TYG8|ensemblmetazoa:FBpp0084103|ensemblmetazoa:FBpp0306645	psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name)	psi-mi:ccnb3_drome(display_long)|uniprotkb:CycB3(gene name)|psi-mi:CycB3(display_short)|uniprotkb:CG5814(orf name)	psi-mi:"MI:0019"(coimmunoprecipitation)	Jacobs et al. (1998)	pubmed:9851980	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-396408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166	refseq:NP_651303.2|flybase:FBgn0015625|refseq:NP_001262934.1|dip:DIP-22205N|ensemblmetazoa:FBgn0015625(gene)|ensemblmetazoa:FBtr0084728(transcript)|ensemblmetazoa:FBtr0334578(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q9I7I0	-	-	-	-	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2004/07/28	2014/10/16	rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227	rogid:x00iO2ghcNgpERCKftXiPiDv+Is7227	intact-crc:5F823C9751A712B8|rigid:KcGjSYGnvr61bB+Z3qeT7HESQG8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)