#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P83917	uniprotkb:Q64127	intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-307946	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:W2npW/vFRcuTkStKpknsAP69q6I10090	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	intact-crc:52CA26B3FDEFB01E|rigid:l+fuNUaxP5JceMzkHVds/uKECCM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:Q61686	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-307983	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	intact-crc:37C7E85AA4058E15|rigid:AxLlh0THNbMgBSo3u2TqwltkvkU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q62318	uniprotkb:Q61686	intact:EBI-346909|uniprotkb:P70391|uniprotkb:Q8C283|uniprotkb:Q99PN4|ensembl:ENSMUSP00000005705	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:tif1b_mouse(display_long)|uniprotkb:Trim28(gene name)|psi-mi:Trim28(display_short)|uniprotkb:Krip1(gene name synonym)|uniprotkb:Tif1b(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:KRAB-A-interacting protein(gene name synonym)|uniprotkb:KRIP-1(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:Kap1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-307986	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035718.2|dip:DIP-31477N|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q62318|rcsb pdb:6O5K|reactome:R-MMU-212436|ensembl:ENSMUSG00000005566(gene)|ensembl:ENSMUST00000005705(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:DvGJxQNohVWs++QEAyrqe4ngcz810090	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	intact-crc:E1A0E60D800DEADA|rigid:bI9oKcdsh0oKlx4l986UHwYm+08	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:Q61686	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346705	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	-	-	-	comment:AA 675-701 of Tif1 sufficient for interaction.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	intact-crc:B8296FBC77247358|rigid:AxLlh0THNbMgBSo3u2TqwltkvkU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:P83917	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N	-	-	-	comment:AA 675-701 of Tif1 sufficient for interaction.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:W2npW/vFRcuTkStKpknsAP69q6I10090	intact-crc:3CA3E5C6ADD79C15|rigid:l+fuNUaxP5JceMzkHVds/uKECCM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:P28700	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564	-	-	-	comment:AA 726-735 sufficient of Tif1 sufficient for interaction.  Interaction is ligand dependent.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090	intact-crc:F6BADB3E619F3282|rigid:AxH1ciCAvXhrdDYmfHMLZEFMIB0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:P11416	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-346736|uniprotkb:P22603|ensembl:ENSMUSP00000069744|ensembl:ENSMUSP00000103098|ensembl:ENSMUSP00000103099|ensembl:ENSMUSP00000129791	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:rara_mouse(display_long)|uniprotkb:Rara(gene name)|psi-mi:Rara(display_short)|uniprotkb:Nr1b1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	refseq:NP_001169999.1|refseq:NP_001170773.1|refseq:NP_001170774.1|refseq:NP_033050.2|refseq:XP_006532655.1|refseq:XP_006532656.1|refseq:XP_017169842.1|dip:DIP-31480N|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060348"(bone development)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|go:"GO:0030852"(regulation of granulocyte differentiation)|ensembl:ENSMUSG00000037992(gene)|ensembl:ENSMUST00000068133(transcript)|ensembl:ENSMUST00000107474(transcript)|ensembl:ENSMUST00000107475(transcript)|ensembl:ENSMUST00000164748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P11416|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9616222	-	-	-	comment:AA 726-735 of Tif1 was sufficient for interaction. In an independent experiment RAR alpha region AA 408-416 was found to be necessary for interaction. Interaction is ligand dependent.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:Au9WAaW0hYj2SCVF3NjQMw0rGOw10090	intact-crc:4114698746706F93|rigid:acb5osam3GP0GAaLhIBwBTGFhqU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:P19785	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-346765|uniprotkb:Q9JJT5|uniprotkb:Q9QY51|uniprotkb:Q9QY52|ensembl:ENSMUSP00000070070|ensembl:ENSMUSP00000101214|ensembl:ENSMUSP00000101215	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:esr1_mouse(display_long)|uniprotkb:Esr1(gene name)|psi-mi:Esr1(display_short)|uniprotkb:Esr(gene name synonym)|uniprotkb:Estr(gene name synonym)|uniprotkb:Estra(gene name synonym)|uniprotkb:Nr3a1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346794	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	refseq:XP_011241368.1|refseq:XP_011241369.1|refseq:XP_011241370.1|refseq:NP_031982.1|refseq:NP_001289460.1|refseq:NP_001289461.1|refseq:XP_006512496.1|refseq:XP_006512497.1|refseq:XP_006512498.1|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-5689896|reactome:R-MMU-6811558|reactome:R-MMU-8866910|reactome:R-MMU-8931987|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9018519|reactome:R-MMU-1257604|go:"GO:0035327"|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042562"(hormone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060011"(Sertoli cell proliferation)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P19785|reactome:R-MMU-1251985|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|ensembl:ENSMUSG00000019768(gene)|ensembl:ENSMUST00000067086(transcript)|ensembl:ENSMUST00000105589(transcript)|ensembl:ENSMUST00000105590(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030315"(T-tubule)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031798"(type 1 metabotropic glutamate receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)	-	-	-	comment:AA 726-735 of Tif1 sufficient for interaction.  Interaction is ligand dependent.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:rGimZuxFcndkD0fWkLb/pZLxcZc10090	intact-crc:E2FF31667EEB2700|rigid:ytzDsWq6V1rGd7cnGUbf1KOkC+4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:P48281	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791	-	-	-	comment:AA 726-735 of Tif1 sufficient for interaction.   Interaction ligand dependent.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090	intact-crc:EA036FBF4C61C7F3|rigid:VJeKDJTRD8ONSUWYfYqbBrjuvTo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:Q00175	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-346821|uniprotkb:A6H6A5|uniprotkb:E9QPW3|ensembl:ENSMUSP00000063562|ensembl:ENSMUSP00000140124	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:prgr_mouse(display_long)|uniprotkb:Pgr(gene name)|psi-mi:Pgr(display_short)|uniprotkb:Nr3c3(gene name synonym)|uniprotkb:Pr(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	refseq:NP_032855.2|ensembl:ENSMUST00000189181(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042220"(response to cocaine)|go:"GO:0042562"(hormone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043679"(axon terminus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060180"(female mating behavior)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:1904709"(negative regulation of granulosa cell apoptotic process)|interpro:IPR000128(Progesterone receptor, N-terminal)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:Q00175|reactome:R-MMU-3371497|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-9018519|ensembl:ENSMUST00000070463(transcript)|ensembl:ENSMUSG00000031870(gene)	-	-	-	comment:AA 726-735 of Tif1 sufficient for interaction.  Interaction ligand dependent.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2017/01/20	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:YHp5BFVM985LT1P6WRmbBUoMc9g10090	intact-crc:C7C78A8C40995690|rigid:yKDmJZcnRYygESgqa6ngDQmirP8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q64127	uniprotkb:Q61686	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346842	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	-	-	-	comment:AA 434-791 of Tif1 interacts with AA 121-180 of HP1 alpha.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	intact-crc:F74DAFF9B69DC542|rigid:AxLlh0THNbMgBSo3u2TqwltkvkU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P83917	uniprotkb:Q64127	intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-346851	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	-	-	-	comment:AA 675-750 of Tif1 sufficient for interaction.  AA 21-67 of MOD1 necessary fo rinteraction.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/04/22	2014/10/16	rogid:W2npW/vFRcuTkStKpknsAP69q6I10090	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	intact-crc:42F839C70C2A8E53|rigid:l+fuNUaxP5JceMzkHVds/uKECCM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q61686	uniprotkb:Q64127	intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-307992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	-	-	-	comment:Tif1 is His tagged. cbx5 is expressed as a GST fusion protein.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/04/22	2014/10/16	rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	intact-crc:2A5EBD6C57F931FB|rigid:AxLlh0THNbMgBSo3u2TqwltkvkU	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P83917	uniprotkb:Q64127	intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475	intact:EBI-307947|uniprotkb:Q64126|ensembl:ENSMUSP00000031859	psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)	psi-mi:tif1a_mouse(display_long)|uniprotkb:Trim24(gene name)|psi-mi:Trim24(display_short)|uniprotkb:Tif1a(gene name synonym)|uniprotkb:Tif1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Trim24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Le et al. (1996)	pubmed:8978696	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-307996	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N	interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|ensembl:ENSMUSG00000029833(gene)|ensembl:ENSMUST00000031859(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR017907|interpro:IPR018359|refseq:NP_001259005.1|interpro:IPR019787|interpro:IPR036427|interpro:IPR019786|mint:Q64127|refseq:NP_659542.3|refseq:NP_001258993.1|dip:DIP-31476N	-	-	-	comment:Tif1alpha is his tagged and CBX1 is expressed as a GST fusion protein.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/04/22	2014/10/16	rogid:W2npW/vFRcuTkStKpknsAP69q6I10090	rogid:F6mVOG5O0f8v9e1ePKYGxtvK5Ts10090	intact-crc:5ECF7B91E33C536B|rigid:l+fuNUaxP5JceMzkHVds/uKECCM	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)